| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
181 | Q9QUS6 | 705 | TRIM1_MOUSE Probable E3 ubiquitin-protein lig... | 59 | 0.81 | 35.8 | 41 | 46 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005874; C:microtubule; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 182 | Q864U1 | 1849 | BRCA1_BOVIN Breast cancer type 1 susceptibili... | 27 | 0.81 | 36.2 | 48 | 59 | GO:0031436; C:BRCA1-BARD1 complex; ISS:UniProtKB. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.::GO:0045717; P:negative regulation of fatty acid biosynthetic process; ISS:UniProtKB.::GO:0051865; P:protein autoubiquitination; ISS:UniProtKB.::GO:0085020; P:protein K6-linked ubiquitination; ISS:UniProtKB. | 183 | Q6P9F5 | 258 | TRI40_HUMAN Tripartite motif-containing prote... | 57 | 0.82 | 35.4 | 32 | 39 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 184 | Q96A37 | 237 | RN166_HUMAN RING finger protein 166 OS=Homo s... | 65 | 0.83 | 35 | 32 | 42 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 185 | Q95153 | 1878 | BRCA1_CANFA Breast cancer type 1 susceptibili... | 27 | 0.84 | 36.2 | 48 | 59 | GO:0031436; C:BRCA1-BARD1 complex; ISS:UniProtKB. | | | | | | | | | | GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.::GO:0045717; P:negative regulation of fatty acid biosynthetic process; ISS:UniProtKB.::GO:0051865; P:protein autoubiquitination; ISS:UniProtKB.::GO:0085020; P:protein K6-linked ubiquitination; ISS:UniProtKB. | 186 | Q9FNG6 | 378 | C3H51_ARATH Zinc finger CCCH domain-containin... | 26 | 0.85 | 35.4 | 46 | 54 | GO:0016020; C:membrane; IDA:TAIR. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 187 | Q55BF8 | 999 | Y1372_DICDI RING finger domain and kelch repe... | 31 | 0.86 | 35.8 | 48 | 55 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005524; F:ATP binding; ISS:dictyBase.::GO:0004672; F:protein kinase activity; ISS:dictyBase.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 188 | P48754 | 1812 | BRCA1_MOUSE Breast cancer type 1 susceptibili... | 27 | 0.88 | 35.8 | 48 | 59 | GO:0031436; C:BRCA1-BARD1 complex; ISS:UniProtKB.::GO:0005813; C:centrosome; TAS:UniProtKB.::GO:0000794; C:condensed nuclear chromosome; IDA:MGI.::GO:0005654; C:nucleoplasm; TAS:Reactome. | | | | | | | | | | GO:0003684; F:damaged DNA binding; IDA:MGI.::GO:0005515; F:protein binding; ISS:UniProtKB.::GO:0044212; F:transcription regulatory region DNA binding; IDA:BHF-UCL.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0051298; P:centrosome duplication; TAS:UniProtKB.::GO:0043009; P:chordate embryonic development; IMP:MGI.::GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006260; P:DNA replication; IMP:MGI.::GO:0009048; P:dosage compensation by inactivation of X chromosome; IDA:MGI.::GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.::GO:0045717; P:negative regulation of fatty acid biosynthetic process; ISS:UniProtKB.::GO:0035067; P:negative regulation of histone acetylation; IMP:BHF-UCL.::GO:0051572; P:negative regulation of histone H3-K4 methylation; IMP:BHF-UCL.::GO:0051573; P:negative regulation of histone H3-K9 methylation; IMP:BHF-UCL.::GO:0051571; P:positive regulation of histone H3-K4 methylation; IMP:BHF-UCL.::GO:2000617; P:positive regulation of histone H3-K9 acetylation; IMP:BHF-UCL.::GO:0051574; P:positive regulation of histone H3-K9 methylation; IMP:BHF-UCL.::GO:2000620; P:positive regulation of histone H4-K16 acetylation; IMP:BHF-UCL.::GO:0070512; P:positive regulation of histone H4-K20 methylation; IMP:BHF-UCL.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.::GO:0051865; P:protein autoubiquitination; ISS:UniProtKB.::GO:0085020; P:protein K6-linked ubiquitination; ISS:UniProtKB.::GO:0044030; P:regulation of DNA methylation; IMP:BHF-UCL.::GO:0006349; P:regulation of gene expression by genetic imprinting; IMP:BHF-UCL. | 189 | Q7ZUK0 | 364 | RN146_DANRE E3 ubiquitin-protein ligase rnf14... | 49 | 0.89 | 35.4 | 35 | 53 | GO:0005829; C:cytosol; ISS:UniProtKB. | | | | | | | | | | GO:0072572; F:poly-ADP-D-ribose binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0090263; P:positive regulation of canonical Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0051865; P:protein autoubiquitination; ISS:UniProtKB.::GO:0070936; P:protein K48-linked ubiquitination; ISS:UniProtKB.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. | 190 | Q1XHT8 | 229 | TRI40_PANTR Tripartite motif-containing prote... | 57 | 0.9 | 35 | 32 | 39 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 191 | O54952 | 1817 | BRCA1_RAT Breast cancer type 1 susceptibility... | 27 | 0.91 | 35.8 | 48 | 59 | GO:0031436; C:BRCA1-BARD1 complex; ISS:UniProtKB.::GO:0005759; C:mitochondrial matrix; IDA:RGD. | | | | | | | | | | GO:0003684; F:damaged DNA binding; TAS:RGD.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007420; P:brain development; IEP:RGD.::GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.::GO:0045717; P:negative regulation of fatty acid biosynthetic process; ISS:UniProtKB.::GO:0051865; P:protein autoubiquitination; ISS:UniProtKB.::GO:0085020; P:protein K6-linked ubiquitination; ISS:UniProtKB.::GO:0032355; P:response to estradiol stimulus; IEP:RGD.::GO:0033993; P:response to lipid; IEP:RGD.::GO:0007584; P:response to nutrient; IEP:RGD. | 192 | Q3UWA4 | 246 | TRI40_MOUSE Tripartite motif-containing prote... | 63 | 0.93 | 35 | 30 | 43 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 193 | Q11096 | 347 | YWZ6_CAEEL Uncharacterized RING finger protei... | 47 | 0.98 | 35.4 | 36 | 49 | | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 194 | P14373 | 513 | TRI27_HUMAN Zinc finger protein RFP OS=Homo s... | 54 | 1.1 | 35.4 | 37 | 46 | GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005887; C:integral to plasma membrane; TAS:ProtInc.::GO:0005624; C:membrane fraction; TAS:ProtInc.::GO:0031965; C:nuclear membrane; IDA:MGI.::GO:0016605; C:PML body; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004714; F:transmembrane receptor protein tyrosine kinase activity; TAS:ProtInc.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0008283; P:cell proliferation; TAS:ProtInc.::GO:0072643; P:interferon-gamma secretion; IMP:UniProtKB.::GO:0002820; P:negative regulation of adaptive immune response; IMP:UniProtKB.::GO:0090281; P:negative regulation of calcium ion import; IMP:UniProtKB.::GO:0045814; P:negative regulation of gene expression, epigenetic; IDA:MGI.::GO:1900041; P:negative regulation of interleukin-2 secretion; IMP:UniProtKB.::GO:0006469; P:negative regulation of protein kinase activity; IDA:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:MGI.::GO:0032720; P:negative regulation of tumor necrosis factor production; IMP:UniProtKB.::GO:0070206; P:protein trimerization; IDA:UniProtKB.::GO:0007283; P:spermatogenesis; TAS:ProtInc.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 195 | Q4WZJ6 | 418 | RAD18_ASPFU Postreplication repair E3 ubiquit... | 40 | 1.1 | 35.4 | 38 | 48 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003684; F:damaged DNA binding; IEA:InterPro.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006281; P:DNA repair; IEA:UniProtKB-KW. | 196 | Q6J6I9 | 1863 | BRCA1_MACMU Breast cancer type 1 susceptibili... | 27 | 1.1 | 35.4 | 48 | 56 | GO:0031436; C:BRCA1-BARD1 complex; ISS:UniProtKB. | | | | | | | | | | GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.::GO:0045717; P:negative regulation of fatty acid biosynthetic process; ISS:UniProtKB.::GO:0051865; P:protein autoubiquitination; ISS:UniProtKB.::GO:0085020; P:protein K6-linked ubiquitination; ISS:UniProtKB. | 197 | Q9BSJ1 | 452 | SPRY5_HUMAN SPRY domain-containing protein 5 ... | 44 | 1.2 | 35 | 39 | 55 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 198 | O00635 | 465 | TRI38_HUMAN Tripartite motif-containing prote... | 75 | 1.2 | 35 | 29 | 41 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0004871; F:signal transducer activity; IMP:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; IMP:UniProtKB. | 199 | A2BTN8 | 455 | CLPX_PROMS ATP-dependent Clp protease ATP-bin... | 76 | 1.2 | 35 | 28 | 49 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.::GO:0046983; F:protein dimerization activity; IEA:InterPro.::GO:0051082; F:unfolded protein binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006457; P:protein folding; IEA:InterPro. | 200 | Q8C0E3 | 641 | TRI47_MOUSE Tripartite motif-containing prote... | 60 | 1.2 | 35.4 | 35 | 40 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 201 | Q1L721 | 222 | RN138_XENLA E3 ubiquitin-protein ligase RNF13... | 80 | 1.2 | 34.7 | 26 | 41 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0031624; F:ubiquitin conjugating enzyme binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0051865; P:protein autoubiquitination; IDA:UniProtKB.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IMP:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. | 202 | Q8IWZ4 | 208 | TRI48_HUMAN Tripartite motif-containing prote... | 31 | 1.3 | 34.7 | 39 | 55 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 203 | Q5AVC5 | 332 | CWC24_EMENI Pre-mRNA-splicing factor cwc24 OS... | 26 | 1.3 | 35 | 42 | 54 | GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW. | 204 | A6NDI0 | 452 | TR49B_HUMAN Putative tripartite motif-contain... | 31 | 1.3 | 35 | 39 | 58 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 205 | Q6ZMU5 | 477 | TRI72_HUMAN Tripartite motif-containing prote... | 82 | 1.4 | 35 | 32 | 43 | GO:0030659; C:cytoplasmic vesicle membrane; ISS:UniProtKB.::GO:0042383; C:sarcolemma; ISS:UniProtKB. | | | | | | | | | | GO:0001786; F:phosphatidylserine binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006887; P:exocytosis; IEA:UniProtKB-KW.::GO:0007517; P:muscle organ development; ISS:UniProtKB.::GO:0003012; P:muscle system process; ISS:UniProtKB.::GO:0001778; P:plasma membrane repair; ISS:UniProtKB.::GO:0051260; P:protein homooligomerization; ISS:UniProtKB. | 206 | Q5C8T6 | 493 | TRIM5_GORGO Tripartite motif-containing prote... | 89 | 1.4 | 35 | 30 | 39 | GO:0000932; C:cytoplasmic mRNA processing body; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 207 | Q5RBG2 | 492 | TRI35_PONAB Tripartite motif-containing prote... | 34 | 1.4 | 35 | 35 | 53 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW. | 208 | Q9UPQ4 | 493 | TRI35_HUMAN Tripartite motif-containing prote... | 34 | 1.4 | 35 | 35 | 53 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0006917; P:induction of apoptosis; ISS:UniProtKB.::GO:0045930; P:negative regulation of mitotic cell cycle; IDA:UniProtKB. | 209 | Q5RKG6 | 501 | TRI35_RAT Tripartite motif-containing protein... | 60 | 1.4 | 35 | 28 | 42 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW. | 210 | Q6NRG0 | 532 | RNF8B_XENLA E3 ubiquitin-protein ligase RNF8-... | 82 | 1.4 | 35 | 26 | 40 | GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0000151; C:ubiquitin ligase complex; ISS:UniProtKB. | | | | | | | | | | GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0042393; F:histone binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0051301; P:cell division; IEA:InterPro.::GO:0006302; P:double-strand break repair; ISS:UniProtKB.::GO:0033522; P:histone H2A ubiquitination; ISS:UniProtKB.::GO:0033523; P:histone H2B ubiquitination; ISS:UniProtKB.::GO:0045739; P:positive regulation of DNA repair; ISS:UniProtKB.::GO:0010212; P:response to ionizing radiation; ISS:UniProtKB. | 211 | Q7ZX20 | 540 | RNF8A_XENLA E3 ubiquitin-protein ligase RNF8-... | 82 | 1.4 | 35 | 24 | 40 | GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0000151; C:ubiquitin ligase complex; ISS:UniProtKB. | | | | | | | | | | GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0042393; F:histone binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0051301; P:cell division; IEA:InterPro.::GO:0006302; P:double-strand break repair; ISS:UniProtKB.::GO:0033522; P:histone H2A ubiquitination; ISS:UniProtKB.::GO:0033523; P:histone H2B ubiquitination; ISS:UniProtKB.::GO:0045739; P:positive regulation of DNA repair; ISS:UniProtKB.::GO:0010212; P:response to ionizing radiation; ISS:UniProtKB. |
