| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | Q4U3Y2 | 549 | HXK1_ASPFU Hexokinase-1 OS=A1100) (Aspergillu... | 577 | 6e-41 | 160 | 27 | 44 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004396; F:hexokinase activity; IEA:EC. | | | | | | | | | | GO:0006096; P:glycolysis; IEA:UniProtKB-KW. | 2 | Q9SQ76 | 496 | HXK2_SOLTU Hexokinase-2 OS=Solanum tuberosum ... | 587 | 4e-33 | 136 | 25 | 43 | GO:0009707; C:chloroplast outer membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004396; F:hexokinase activity; IEA:EC. | | | | | | | | | | GO:0006096; P:glycolysis; IEA:UniProtKB-KW. | 3 | Q9NFT7 | 486 | HXK2_DROME Hexokinase type 2 OS=Drosophila me... | 408 | 8e-32 | 132 | 29 | 43 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004396; F:hexokinase activity; NAS:UniProtKB. | | | | | | | | | | GO:0006096; P:glycolysis; NAS:UniProtKB. | 4 | Q9SEK2 | 497 | HXK1_TOBAC Hexokinase-1 OS=Nicotiana tabacum ... | 561 | 5e-31 | 130 | 26 | 42 | GO:0009707; C:chloroplast outer membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004396; F:hexokinase activity; IEA:EC. | | | | | | | | | | GO:0006096; P:glycolysis; IEA:UniProtKB-KW. | 5 | P35557 | 465 | HXK4_HUMAN Glucokinase OS=Homo sapiens (Human... | 404 | 1e-29 | 125 | 27 | 45 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005654; C:nucleoplasm; TAS:Reactome. | | | | | | | | | | GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0004340; F:glucokinase activity; IDA:UniProtKB.::GO:0005536; F:glucose binding; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0032869; P:cellular response to insulin stimulus; ISS:BHF-UCL.::GO:0044320; P:cellular response to leptin stimulus; ISS:BHF-UCL.::GO:0051594; P:detection of glucose; IMP:UniProtKB.::GO:0031018; P:endocrine pancreas development; TAS:Reactome.::GO:0042593; P:glucose homeostasis; IMP:UniProtKB.::GO:0015758; P:glucose transport; TAS:Reactome.::GO:0006096; P:glycolysis; IEA:UniProtKB-KW.::GO:0045721; P:negative regulation of gluconeogenesis; IMP:UniProtKB.::GO:0045725; P:positive regulation of glycogen biosynthetic process; IMP:UniProtKB.::GO:0032024; P:positive regulation of insulin secretion; IMP:UniProtKB.::GO:0010827; P:regulation of glucose transport; TAS:Reactome.::GO:0006110; P:regulation of glycolysis; NAS:BHF-UCL.::GO:0055085; P:transmembrane transport; TAS:Reactome. | 6 | P50521 | 455 | HXK2_SCHPO Hexokinase-2 OS=Schizosaccharomyce... | 419 | 2e-28 | 122 | 28 | 43 | GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008865; F:fructokinase activity; IDA:PomBase.::GO:0004340; F:glucokinase activity; IDA:PomBase.::GO:0019158; F:mannokinase activity; IDA:PomBase. | | | | | | | | | | GO:0006002; P:fructose 6-phosphate metabolic process; IDA:PomBase.::GO:0006096; P:glycolysis; IEA:UniProtKB-KW.::GO:0006013; P:mannose metabolic process; IDA:PomBase. | 7 | Q26609 | 451 | HXK_SCHMA Hexokinase OS=Schistosoma mansoni (... | 351 | 2e-28 | 122 | 30 | 46 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004396; F:hexokinase activity; IEA:EC. | | | | | | | | | | GO:0006096; P:glycolysis; IEA:UniProtKB-KW. | 8 | P17712 | 465 | HXK4_RAT Glucokinase OS=Rattus norvegicus (Ra... | 404 | 3e-28 | 121 | 27 | 46 | GO:0044448; C:cell cortex part; IDA:RGD.::GO:0005829; C:cytosol; IDA:RGD.::GO:0005739; C:mitochondrion; IDA:RGD.::GO:0005654; C:nucleoplasm; IDA:RGD.::GO:0030141; C:secretory granule; IDA:RGD. | | | | | | | | | | GO:0043531; F:ADP binding; IDA:RGD.::GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0004340; F:glucokinase activity; ISS:UniProtKB.::GO:0005536; F:glucose binding; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; IDA:RGD.::GO:0019903; F:protein phosphatase binding; IPI:RGD. | | | | | | | | | | GO:0001678; P:cellular glucose homeostasis; IMP:RGD.::GO:0042149; P:cellular response to glucose starvation; IMP:RGD.::GO:0032869; P:cellular response to insulin stimulus; IDA:BHF-UCL.::GO:0044320; P:cellular response to leptin stimulus; IDA:BHF-UCL.::GO:0051594; P:detection of glucose; ISS:UniProtKB.::GO:0007204; P:elevation of cytosolic calcium ion concentration; IDA:RGD.::GO:0006003; P:fructose 2,6-bisphosphate metabolic process; IDA:RGD.::GO:0005978; P:glycogen biosynthetic process; IDA:RGD.::GO:0006096; P:glycolysis; IDA:RGD.::GO:0032811; P:negative regulation of epinephrine secretion; IMP:RGD.::GO:0045721; P:negative regulation of gluconeogenesis; ISS:UniProtKB.::GO:0045725; P:positive regulation of glycogen biosynthetic process; ISS:UniProtKB.::GO:0045821; P:positive regulation of glycolysis; IDA:RGD.::GO:0032024; P:positive regulation of insulin secretion; ISS:UniProtKB.::GO:0042327; P:positive regulation of phosphorylation; IDA:RGD.::GO:0019932; P:second-messenger-mediated signaling; IDA:RGD. | 9 | P33284 | 485 | HXK_KLULA Hexokinase OS=1267 / NRRL Y-1140 / ... | 465 | 7e-28 | 120 | 25 | 43 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004396; F:hexokinase activity; IEA:EC. | | | | | | | | | | GO:0006096; P:glycolysis; IEA:UniProtKB-KW. | 10 | P52792 | 465 | HXK4_MOUSE Glucokinase OS=Mus musculus (Mouse... | 404 | 2e-27 | 119 | 26 | 45 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005739; C:mitochondrion; IDA:MGI.::GO:0005625; C:soluble fraction; IDA:MGI. | | | | | | | | | | GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0004340; F:glucokinase activity; ISS:UniProtKB.::GO:0005536; F:glucose binding; ISS:UniProtKB. | | | | | | | | | | GO:0070509; P:calcium ion import; IMP:UniProtKB.::GO:0001678; P:cellular glucose homeostasis; IMP:MGI.::GO:0051594; P:detection of glucose; ISS:UniProtKB.::GO:0031018; P:endocrine pancreas development; TAS:Reactome.::GO:0006096; P:glycolysis; IEA:UniProtKB-KW.::GO:0006739; P:NADP metabolic process; IMP:MGI.::GO:0045721; P:negative regulation of gluconeogenesis; ISS:UniProtKB.::GO:0045725; P:positive regulation of glycogen biosynthetic process; ISS:UniProtKB.::GO:0032024; P:positive regulation of insulin secretion; IMP:UniProtKB.::GO:0043266; P:regulation of potassium ion transport; IMP:MGI. | 11 | O08528 | 917 | HXK2_MOUSE Hexokinase-2 OS=Mus musculus (Mous... | 455 | 7e-26 | 117 | 27 | 41 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004396; F:hexokinase activity; IDA:MGI. | | | | | | | | | | GO:0006096; P:glycolysis; IEA:UniProtKB-KW.::GO:0046324; P:regulation of glucose import; IMP:MGI. | 12 | Q9SEK3 | 498 | HXK1_SPIOL Hexokinase-1 OS=Spinacia oleracea ... | 572 | 6e-27 | 118 | 25 | 40 | GO:0009707; C:chloroplast outer membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004396; F:hexokinase activity; IEA:EC. | | | | | | | | | | GO:0006096; P:glycolysis; IEA:UniProtKB-KW. | 13 | P50506 | 478 | HXK_SCHOC Hexokinase OS=Schwanniomyces occide... | 467 | 6e-27 | 117 | 26 | 45 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004396; F:hexokinase activity; IEA:EC. | | | | | | | | | | GO:0006096; P:glycolysis; IEA:UniProtKB-KW. | 14 | P27881 | 917 | HXK2_RAT Hexokinase-2 OS=Rattus norvegicus (R... | 455 | 3e-26 | 118 | 27 | 41 | GO:0005741; C:mitochondrial outer membrane; TAS:RGD. | | | | | | | | | | GO:0005524; F:ATP binding; IDA:RGD.::GO:0005536; F:glucose binding; IDA:RGD.::GO:0004396; F:hexokinase activity; IDA:RGD. | | | | | | | | | | GO:0006096; P:glycolysis; IEA:UniProtKB-KW.::GO:0007595; P:lactation; IEP:RGD. | 15 | Q91W97 | 915 | HKDC1_MOUSE Putative hexokinase HKDC1 OS=Mus ... | 317 | 7e-26 | 116 | 30 | 43 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004396; F:hexokinase activity; IEA:EC. | | | | | | | | | | GO:0006096; P:glycolysis; IEA:UniProtKB-KW. | 16 | P80581 | 490 | HXK_EMENI Hexokinase OS=194 / M139) (Aspergil... | 483 | 1e-26 | 117 | 27 | 45 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004396; F:hexokinase activity; IEA:EC. | | | | | | | | | | GO:0006096; P:glycolysis; IEA:UniProtKB-KW. | 17 | Q1W674 | 917 | HXK2_PIG Hexokinase-2 OS=Sus scrofa (Pig). GN... | 362 | 2e-24 | 112 | 27 | 43 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004396; F:hexokinase activity; IEA:EC. | | | | | | | | | | GO:0006096; P:glycolysis; IEA:UniProtKB-KW. | 18 | Q09756 | 484 | HXK1_SCHPO Hexokinase-1 OS=Schizosaccharomyce... | 422 | 2e-26 | 116 | 28 | 44 | GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008865; F:fructokinase activity; IDA:PomBase.::GO:0004340; F:glucokinase activity; IDA:PomBase.::GO:0019158; F:mannokinase activity; IDA:PomBase. | | | | | | | | | | GO:0006002; P:fructose 6-phosphate metabolic process; IDA:PomBase.::GO:0006096; P:glycolysis; IC:PomBase.::GO:0006013; P:mannose metabolic process; IDA:PomBase.::GO:0009051; P:pentose-phosphate shunt, oxidative branch; TAS:PomBase. | 19 | Q2KNB7 | 502 | HXK9_ORYSJ Hexokinase-9 OS=Oryza sativa subsp... | 545 | 4e-26 | 115 | 25 | 41 | GO:0009707; C:chloroplast outer membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004396; F:hexokinase activity; IEA:EC. | | | | | | | | | | GO:0006096; P:glycolysis; IEA:UniProtKB-KW. | 20 | Q2TB90 | 917 | HKDC1_HUMAN Putative hexokinase HKDC1 OS=Homo... | 314 | 2e-24 | 112 | 29 | 44 | GO:0005739; C:mitochondrion; IDA:HPA.::GO:0005634; C:nucleus; IDA:HPA. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004396; F:hexokinase activity; IEA:EC. | | | | | | | | | | GO:0006096; P:glycolysis; IEA:UniProtKB-KW. | 21 | Q5RC71 | 917 | HXK1_PONAB Hexokinase-1 OS=Pongo abelii (Suma... | 473 | 9e-22 | 103 | 24 | 42 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004396; F:hexokinase activity; IEA:EC. | | | | | | | | | | GO:0006096; P:glycolysis; IEA:UniProtKB-KW. | 22 | Q42525 | 496 | HXK1_ARATH Hexokinase-1 OS=Arabidopsis thalia... | 560 | 1e-25 | 114 | 25 | 42 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:TAIR.::GO:0009536; C:plastid; IDA:TAIR.::GO:0005774; C:vacuolar membrane; IDA:TAIR. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008865; F:fructokinase activity; IDA:TAIR.::GO:0004340; F:glucokinase activity; IDA:TAIR.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0008270; F:zinc ion binding; IDA:TAIR. | | | | | | | | | | GO:0010255; P:glucose mediated signaling pathway; IMP:TAIR.::GO:0006096; P:glycolysis; IEA:UniProtKB-KW.::GO:0012501; P:programmed cell death; IMP:TAIR. | 23 | P52789 | 917 | HXK2_HUMAN Hexokinase-2 OS=Homo sapiens (Huma... | 315 | 2e-22 | 106 | 28 | 43 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005741; C:mitochondrial outer membrane; IDA:MGI. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004396; F:hexokinase activity; TAS:ProtInc. | | | | | | | | | | GO:0008637; P:apoptotic mitochondrial changes; IDA:MGI.::GO:0015758; P:glucose transport; TAS:Reactome.::GO:0006096; P:glycolysis; IEA:UniProtKB-KW.::GO:0055085; P:transmembrane transport; TAS:Reactome. | 24 | Q6Z398 | 509 | HXK4_ORYSJ Hexokinase-4, chloroplastic OS=Ory... | 412 | 2e-25 | 114 | 26 | 42 | GO:0009570; C:chloroplast stroma; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006096; P:glycolysis; IEA:UniProtKB-KW. | 25 | P17710 | 974 | HXK1_MOUSE Hexokinase-1 OS=Mus musculus (Mous... | 479 | 1e-22 | 106 | 24 | 41 | GO:0005829; C:cytosol; IDA:MGI.::GO:0045121; C:membrane raft; IDA:MGI.::GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004396; F:hexokinase activity; IDA:MGI. | | | | | | | | | | GO:0006096; P:glycolysis; TAS:MGI. | 26 | P19367 | 917 | HXK1_HUMAN Hexokinase-1 OS=Homo sapiens (Huma... | 473 | 2e-22 | 106 | 24 | 42 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:HPA. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004396; F:hexokinase activity; TAS:ProtInc. | | | | | | | | | | GO:0015758; P:glucose transport; TAS:Reactome.::GO:0006096; P:glycolysis; TAS:ProtInc.::GO:0055085; P:transmembrane transport; TAS:Reactome. | 27 | Q92407 | 495 | HXKG_ASPNG Glucokinase OS=Aspergillus niger. ... | 435 | 3e-25 | 113 | 25 | 42 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004340; F:glucokinase activity; IEA:EC. | | | | | | | | | | GO:0006096; P:glycolysis; IEA:UniProtKB-KW. | 28 | P05708 | 918 | HXK1_RAT Hexokinase-1 OS=Rattus norvegicus (R... | 387 | 1e-21 | 103 | 25 | 43 | GO:0005901; C:caveola; IDA:RGD.::GO:0005829; C:cytosol; IDA:RGD.::GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.::GO:0043234; C:protein complex; IDA:RGD. | | | | | | | | | | GO:0005524; F:ATP binding; IDA:RGD.::GO:0016887; F:ATPase activity; IC:RGD.::GO:0004340; F:glucokinase activity; IDA:RGD.::GO:0005536; F:glucose binding; IDA:RGD.::GO:0032403; F:protein complex binding; IDA:RGD.::GO:0042803; F:protein homodimerization activity; IDA:RGD.::GO:0004672; F:protein kinase activity; IDA:RGD. | | | | | | | | | | GO:0006096; P:glycolysis; IDA:RGD.::GO:0043066; P:negative regulation of apoptotic process; IMP:RGD.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:RGD.::GO:0018107; P:peptidyl-threonine phosphorylation; IDA:RGD.::GO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:RGD.::GO:0046777; P:protein autophosphorylation; IDA:RGD.::GO:0010359; P:regulation of anion channel activity; IDA:RGD. | 29 | P27595 | 918 | HXK1_BOVIN Hexokinase-1 OS=Bos taurus (Bovine... | 473 | 4e-17 | 89 | 22 | 40 | GO:0005829; C:cytosol; ISS:AgBase.::GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004396; F:hexokinase activity; ISS:AgBase. | | | | | | | | | | GO:0006096; P:glycolysis; IEA:UniProtKB-KW. | 30 | A2PYL6 | 917 | HXK2_HORSE Hexokinase-2 OS=Equus caballus (Ho... | 457 | 4e-24 | 111 | 26 | 42 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004396; F:hexokinase activity; IEA:EC. | | | | | | | | | | GO:0006096; P:glycolysis; IEA:UniProtKB-KW. | 31 | A2PYL7 | 917 | HXK2_EQUZE Hexokinase-2 OS=Equus zebra (Mount... | 457 | 4e-24 | 111 | 26 | 42 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004396; F:hexokinase activity; IEA:EC. | | | | | | | | | | GO:0006096; P:glycolysis; IEA:UniProtKB-KW. |
