| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
541 | Q6R0J2 | 292 | DHI1_MESAU Corticosteroid 11-beta-dehydrogena... | 241 | 0.013 | 40.4 | 28 | 44 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0070524; F:11-beta-hydroxysteroid dehydrogenase (NADP+) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0008202; P:steroid metabolic process; IEA:UniProtKB-KW. | 542 | Q4V8F9 | 524 | HSDL2_RAT Hydroxysteroid dehydrogenase-like p... | 136 | 0.013 | 40.8 | 27 | 48 | GO:0005777; C:peroxisome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.::GO:0032934; F:sterol binding; IEA:InterPro. | | | | | | | | | | | 543 | P54398 | 256 | FBP2_DROME Fat body protein 2 OS=Drosophila m... | 258 | 0.014 | 40 | 21 | 40 | GO:0005811; C:lipid particle; IDA:FlyBase. | | | | | | | | | | GO:0004022; F:alcohol dehydrogenase (NAD) activity; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0045735; F:nutrient reservoir activity; NAS:UniProtKB. | | | | | | | | | | | 544 | Q1RMJ5 | 311 | DRS7C_BOVIN Dehydrogenase/reductase SDR famil... | 211 | 0.015 | 40 | 27 | 43 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 545 | Q9VLU5 | 409 | WWOX_DROME WW domain-containing oxidoreductas... | 228 | 0.015 | 40.4 | 23 | 39 | GO:0005737; C:cytoplasm; IDA:UniProtKB. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:2000377; P:regulation of reactive oxygen species metabolic process; IMP:FlyBase.::GO:0010212; P:response to ionizing radiation; IMP:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. | 546 | P12854 | 254 | ADH1_DRONA Alcohol dehydrogenase 1 OS=Drosoph... | 193 | 0.015 | 40 | 25 | 41 | | | | | | | | | | | GO:0004022; F:alcohol dehydrogenase (NAD) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006066; P:alcohol metabolic process; IEA:InterPro. | 547 | Q9NZC7 | 414 | WWOX_HUMAN WW domain-containing oxidoreductas... | 120 | 0.016 | 40.4 | 28 | 41 | GO:0005829; C:cytosol; IDA:BHF-UCL.::GO:0005794; C:Golgi apparatus; IDA:UniProtKB.::GO:0005739; C:mitochondrion; ISS:BHF-UCL.::GO:0005634; C:nucleus; IDA:BHF-UCL. | | | | | | | | | | GO:0050662; F:coenzyme binding; TAS:UniProtKB.::GO:0019899; F:enzyme binding; IPI:BHF-UCL.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; NAS:UniProtKB.::GO:0046983; F:protein dimerization activity; TAS:UniProtKB. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0071560; P:cellular response to transforming growth factor beta stimulus; IDA:BHF-UCL.::GO:0006917; P:induction of apoptosis; ISS:BHF-UCL.::GO:0030178; P:negative regulation of Wnt receptor signaling pathway; IDA:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:BHF-UCL.::GO:0048705; P:skeletal system morphogenesis; ISS:BHF-UCL.::GO:0008202; P:steroid metabolic process; TAS:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. | 548 | P48587 | 254 | ADH2_DROMN Alcohol dehydrogenase 2 OS=Drosoph... | 207 | 0.017 | 39.7 | 22 | 40 | | | | | | | | | | | GO:0004022; F:alcohol dehydrogenase (NAD) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006066; P:alcohol metabolic process; IEA:InterPro. | 549 | P27581 | 254 | ADH2_DROAR Alcohol dehydrogenase 2 OS=Drosoph... | 193 | 0.017 | 39.7 | 25 | 41 | | | | | | | | | | | GO:0004022; F:alcohol dehydrogenase (NAD) activity; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006066; P:alcohol metabolic process; IEA:InterPro. | 550 | Q6WAU1 | 314 | IPIPR_MENPI (-)-isopiperitenone reductase OS=... | 123 | 0.018 | 40 | 29 | 43 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0052581; F:(-)-isopiperitenone reductase activity; IDA:UniProtKB.::GO:0070402; F:NADPH binding; IDA:UniProtKB. | | | | | | | | | | GO:0031525; P:menthol biosynthetic process; IDA:UniProtKB. | 551 | Q5RCU5 | 277 | CBR1_PONAB Carbonyl reductase [NADPH] 1 OS=Po... | 239 | 0.018 | 39.7 | 26 | 39 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0047021; F:15-hydroxyprostaglandin dehydrogenase (NADP+) activity; IEA:EC.::GO:0004090; F:carbonyl reductase (NADPH) activity; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0050221; F:prostaglandin-E2 9-reductase activity; IEA:EC. | | | | | | | | | | GO:0017144; P:drug metabolic process; ISS:UniProtKB.::GO:0042373; P:vitamin K metabolic process; ISS:UniProtKB. | 552 | Q4V8B7 | 330 | HSDL1_RAT Inactive hydroxysteroid dehydrogena... | 234 | 0.019 | 40 | 21 | 39 | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:InterPro. | | | | | | | | | | | 553 | P48586 | 254 | ADH1_DROMN Alcohol dehydrogenase 1 OS=Drosoph... | 208 | 0.02 | 39.7 | 23 | 41 | | | | | | | | | | | GO:0004022; F:alcohol dehydrogenase (NAD) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006066; P:alcohol metabolic process; IEA:InterPro. | 554 | P29147 | 343 | BDH_RAT D-beta-hydroxybutyrate dehydrogenase,... | 277 | 0.02 | 40 | 24 | 40 | GO:0005743; C:mitochondrial inner membrane; IDA:RGD.::GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003858; F:3-hydroxybutyrate dehydrogenase activity; IDA:RGD.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0005543; F:phospholipid binding; IDA:RGD. | | | | | | | | | | GO:0060612; P:adipose tissue development; IEP:RGD.::GO:0007420; P:brain development; IEP:RGD.::GO:0001889; P:liver development; IEP:RGD.::GO:0046686; P:response to cadmium ion; IEP:RGD.::GO:0051412; P:response to corticosterone stimulus; IEP:RGD.::GO:0042493; P:response to drug; IEP:RGD.::GO:0032355; P:response to estradiol stimulus; IEP:RGD.::GO:0045471; P:response to ethanol; IEP:RGD.::GO:0060416; P:response to growth hormone stimulus; IEP:RGD.::GO:0032868; P:response to insulin stimulus; IEP:RGD.::GO:0007584; P:response to nutrient; IEP:RGD.::GO:0042594; P:response to starvation; IEP:RGD.::GO:0009636; P:response to toxin; IEP:RGD. | 555 | P07160 | 254 | ADH2_DROMU Alcohol dehydrogenase 2 OS=Drosoph... | 193 | 0.021 | 39.7 | 25 | 41 | | | | | | | | | | | GO:0004022; F:alcohol dehydrogenase (NAD) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006066; P:alcohol metabolic process; IEA:InterPro. | 556 | P28845 | 292 | DHI1_HUMAN Corticosteroid 11-beta-dehydrogena... | 176 | 0.021 | 39.7 | 30 | 44 | GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0070524; F:11-beta-hydroxysteroid dehydrogenase (NADP+) activity; IEA:EC.::GO:0003845; F:11-beta-hydroxysteroid dehydrogenase [NAD(P) activity; TAS:Reactome.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006704; P:glucocorticoid biosynthetic process; TAS:Reactome.::GO:0044281; P:small molecule metabolic process; TAS:Reactome.] | 557 | Q5R9W5 | 414 | WWOX_PONAB WW domain-containing oxidoreductas... | 212 | 0.022 | 40 | 24 | 38 | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0030178; P:negative regulation of Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. | 558 | P51549 | 254 | ADH_DROHA Alcohol dehydrogenase OS=Drosophila... | 187 | 0.022 | 39.3 | 24 | 42 | | | | | | | | | | | GO:0004022; F:alcohol dehydrogenase (NAD) activity; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006066; P:alcohol metabolic process; IEA:InterPro. | 559 | P23236 | 254 | ADH1_DROHY Alcohol dehydrogenase 1 OS=Drosoph... | 193 | 0.022 | 39.3 | 25 | 43 | | | | | | | | | | | GO:0004022; F:alcohol dehydrogenase (NAD) activity; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006066; P:alcohol metabolic process; IEA:InterPro. | 560 | O54939 | 306 | DHB3_RAT Testosterone 17-beta-dehydrogenase 3... | 243 | 0.022 | 39.7 | 24 | 40 | GO:0005792; C:microsome; IDA:RGD. | | | | | | | | | | GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IDA:RGD.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0050327; F:testosterone 17-beta-dehydrogenase (NAD+) activity; IDA:RGD.::GO:0047045; F:testosterone 17-beta-dehydrogenase (NADP+) activity; IEA:EC. | | | | | | | | | | GO:0018879; P:biphenyl metabolic process; IEP:RGD.::GO:0071236; P:cellular response to antibiotic; IEP:RGD.::GO:0071371; P:cellular response to gonadotropin stimulus; IEP:RGD.::GO:0021766; P:hippocampus development; IEP:RGD.::GO:0017143; P:insecticide metabolic process; IEP:RGD.::GO:0033327; P:Leydig cell differentiation; IEP:RGD.::GO:0006082; P:organic acid metabolic process; IEP:RGD.::GO:0018958; P:phenol-containing compound metabolic process; IEP:RGD.::GO:0014823; P:response to activity; IEP:RGD.::GO:0046685; P:response to arsenic-containing substance; IEP:RGD.::GO:0046686; P:response to cadmium ion; IEP:RGD.::GO:0051412; P:response to corticosterone stimulus; IEP:RGD.::GO:0043627; P:response to estrogen stimulus; IEP:RGD.::GO:0045471; P:response to ethanol; IEP:RGD.::GO:0070542; P:response to fatty acid; IEP:RGD.::GO:0060992; P:response to fungicide; IEP:RGD.::GO:0009635; P:response to herbicide; IEP:RGD.::GO:0033591; P:response to L-ascorbic acid; IEP:RGD.::GO:0010288; P:response to lead ion; IEP:RGD.::GO:0014070; P:response to organic cyclic compound; IEP:RGD.::GO:0033197; P:response to vitamin E; IEP:RGD.::GO:0006694; P:steroid biosynthetic process; IDA:RGD. | 561 | Q59V93 | 349 | MKAR_CANAL 3-ketoacyl-CoA reductase OS=Candid... | 208 | 0.023 | 39.7 | 25 | 41 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW. | 562 | P50172 | 292 | DHI1_MOUSE Corticosteroid 11-beta-dehydrogena... | 206 | 0.023 | 39.7 | 28 | 43 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0070524; F:11-beta-hydroxysteroid dehydrogenase (NADP+) activity; IEA:EC.::GO:0003845; F:11-beta-hydroxysteroid dehydrogenase [NAD(P) activity; IDA:MGI.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0030324; P:lung development; IMP:MGI.::GO:0008202; P:steroid metabolic process; IEA:UniProtKB-KW.] | 563 | P48585 | 254 | ADH_DROFL Alcohol dehydrogenase OS=Drosophila... | 207 | 0.023 | 39.3 | 22 | 40 | | | | | | | | | | | GO:0004022; F:alcohol dehydrogenase (NAD) activity; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006066; P:alcohol metabolic process; IEA:InterPro. | 564 | P24267 | 254 | ADH2_DROWH Alcohol dehydrogenase 2 OS=Drosoph... | 193 | 0.024 | 39.3 | 25 | 40 | | | | | | | | | | | GO:0004022; F:alcohol dehydrogenase (NAD) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006066; P:alcohol metabolic process; IEA:InterPro. | 565 | P40579 | 254 | YIV5_YEAST Uncharacterized oxidoreductase YIR... | 204 | 0.024 | 39.3 | 25 | 47 | GO:0005737; C:cytoplasm; IDA:SGD. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 566 | Q2TPA8 | 490 | HSDL2_MOUSE Hydroxysteroid dehydrogenase-like... | 300 | 0.025 | 39.7 | 22 | 38 | GO:0005739; C:mitochondrion; IDA:MGI.::GO:0005777; C:peroxisome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.::GO:0032934; F:sterol binding; IEA:InterPro. | | | | | | | | | | | 567 | A6ZLA1 | 347 | MKAR_YEAS7 3-ketoacyl-CoA reductase OS=Saccha... | 209 | 0.025 | 39.7 | 26 | 43 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW. | 568 | B3LN00 | 347 | MKAR_YEAS1 3-ketoacyl-CoA reductase OS=Saccha... | 209 | 0.025 | 39.7 | 26 | 43 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW. | 569 | P25721 | 254 | ADH_DROMY Alcohol dehydrogenase OS=Drosophila... | 193 | 0.026 | 39.3 | 25 | 41 | | | | | | | | | | | GO:0004022; F:alcohol dehydrogenase (NAD) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006066; P:alcohol metabolic process; IEA:InterPro. | 570 | Q5BL28 | 318 | DS7CB_DANRE Dehydrogenase/reductase SDR famil... | 203 | 0.027 | 39.3 | 23 | 44 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 571 | Q27404 | 254 | ADH_DROLA Alcohol dehydrogenase OS=Drosophila... | 207 | 0.028 | 39.3 | 22 | 40 | | | | | | | | | | | GO:0004022; F:alcohol dehydrogenase (NAD) activity; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006066; P:alcohol metabolic process; IEA:InterPro. |
