rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
181 | P16543 | 249 | DHK2_STRVN Granaticin polyketide synthase put... | 275 | 0.000000000000003 | 77 | 28 | 44 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0017000; P:antibiotic biosynthetic process; IEA:UniProtKB-KW. | 182 | Q8VID1 | 279 | DHRS4_RAT Dehydrogenase/reductase SDR family ... | 256 | 0.000000000000003 | 77.4 | 26 | 46 | GO:0005739; C:mitochondrion; ISS:UniProtKB.::GO:0005777; C:peroxisome; IDA:RGD. | | | | | | | | | | GO:0004090; F:carbonyl reductase (NADPH) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | | 183 | Q21929 | 251 | DCXR_CAEEL Probable L-xylulose reductase OS=C... | 257 | 0.000000000000003 | 77 | 29 | 43 | GO:0005886; C:plasma membrane; IDA:WormBase. | | | | | | | | | | GO:0050038; F:L-xylulose reductase (NADP+) activity; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0042732; P:D-xylose metabolic process; IEA:UniProtKB-KW.::GO:0006006; P:glucose metabolic process; ISS:UniProtKB.::GO:0051289; P:protein homotetramerization; ISS:UniProtKB.::GO:0005998; P:xylulose catabolic process; IDA:WormBase. | 184 | Q49WS9 | 246 | Y1627_STAS1 Uncharacterized oxidoreductase SS... | 262 | 0.000000000000006 | 76.3 | 30 | 47 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 185 | Q68ER2 | 236 | CBR4_XENTR Carbonyl reductase family member 4... | 195 | 0.000000000000007 | 75.9 | 27 | 45 | GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW. | 186 | P51659 | 736 | DHB4_HUMAN Peroxisomal multifunctional enzyme... | 201 | 0.000000000000008 | 78.6 | 31 | 50 | GO:0005782; C:peroxisomal matrix; TAS:Reactome. | | | | | | | | | | GO:0003857; F:3-hydroxyacyl-CoA dehydrogenase activity; TAS:Reactome.::GO:0033989; F:3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity; TAS:Reactome.::GO:0016853; F:isomerase activity; IEA:UniProtKB-KW.::GO:0016508; F:long-chain-enoyl-CoA hydratase activity; TAS:Reactome.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0032934; F:sterol binding; IEA:InterPro. | | | | | | | | | | GO:0008209; P:androgen metabolic process; IDA:UniProtKB.::GO:0006699; P:bile acid biosynthetic process; TAS:Reactome.::GO:0008210; P:estrogen metabolic process; IDA:UniProtKB.::GO:0033540; P:fatty acid beta-oxidation using acyl-CoA oxidase; TAS:Reactome. | 187 | Q99LB2 | 279 | DHRS4_MOUSE Dehydrogenase/reductase SDR famil... | 256 | 0.000000000000009 | 76.3 | 27 | 46 | GO:0005739; C:mitochondrion; IDA:UniProtKB.::GO:0005777; C:peroxisome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004090; F:carbonyl reductase (NADPH) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | | 188 | Q9XT00 | 259 | DHB8_PIG Estradiol 17-beta-dehydrogenase 8 OS... | 265 | 0.000000000000009 | 75.9 | 28 | 47 | GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004303; F:estradiol 17-beta-dehydrogenase activity; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0050327; F:testosterone 17-beta-dehydrogenase (NAD+) activity; IEA:EC. | | | | | | | | | | GO:0006703; P:estrogen biosynthetic process; ISS:UniProtKB.::GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW. | 189 | O70351 | 261 | HCD2_RAT 3-hydroxyacyl-CoA dehydrogenase type... | 217 | 0.00000000000001 | 75.9 | 29 | 46 | | | | | | | | | | | GO:0047015; F:3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity; IEA:EC.::GO:0003857; F:3-hydroxyacyl-CoA dehydrogenase activity; IEA:EC.::GO:0018454; F:acetoacetyl-CoA reductase activity; IDA:RGD.::GO:0001540; F:beta-amyloid binding; IDA:RGD.::GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IDA:RGD.::GO:0030331; F:estrogen receptor binding; IPI:RGD.::GO:0042802; F:identical protein binding; IDA:RGD.::GO:0051287; F:NAD binding; IDA:RGD.::GO:0005496; F:steroid binding; IDA:RGD. | | | | | | | | | | GO:0007569; P:cell aging; IEP:RGD.::GO:0033327; P:Leydig cell differentiation; IEP:RGD.::GO:0051289; P:protein homotetramerization; IDA:RGD.::GO:0008033; P:tRNA processing; IEA:UniProtKB-KW. | 190 | O00058 | 256 | MTDH_UROFA Probable NADP-dependent mannitol d... | 262 | 0.00000000000001 | 75.5 | 33 | 47 | | | | | | | | | | | GO:0050085; F:mannitol 2-dehydrogenase (NADP+) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | | 191 | P50203 | 248 | PHAB_ACISR Acetoacetyl-CoA reductase OS=Acine... | 257 | 0.00000000000002 | 74.7 | 31 | 47 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0018454; F:acetoacetyl-CoA reductase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0042619; P:poly-hydroxybutyrate biosynthetic process; IEA:InterPro. | 192 | O93868 | 262 | MTDH_AGABI NADP-dependent mannitol dehydrogen... | 264 | 0.00000000000002 | 75.1 | 31 | 45 | | | | | | | | | | | GO:0050085; F:mannitol 2-dehydrogenase (NADP+) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | | 193 | Q8WNV7 | 279 | DHRS4_PIG Dehydrogenase/reductase SDR family ... | 258 | 0.00000000000002 | 75.1 | 27 | 47 | GO:0005739; C:mitochondrion; ISS:UniProtKB.::GO:0005777; C:peroxisome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004090; F:carbonyl reductase (NADPH) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | | 194 | Q56841 | 249 | HCDS_XANP2 2-(S)-hydroxypropyl-CoM dehydrogen... | 262 | 0.00000000000002 | 74.7 | 31 | 45 | | | | | | | | | | | GO:0050575; F:2-(S)-hydroxypropyl-CoM dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | | 195 | P19992 | 255 | HSD_STREX 3-alpha-(or 20-beta)-hydroxysteroid... | 204 | 0.00000000000002 | 74.7 | 34 | 47 | | | | | | | | | | | GO:0047044; F:androstan-3-alpha,17-beta-diol dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0008202; P:steroid metabolic process; IEA:UniProtKB-KW. | 196 | P37769 | 253 | KDUD_ECOLI 2-dehydro-3-deoxy-D-gluconate 5-de... | 262 | 0.00000000000002 | 74.7 | 27 | 44 | | | | | | | | | | | GO:0047001; F:2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase activity; IEA:EC.::GO:0008678; F:2-deoxy-D-gluconate 3-dehydrogenase activity; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | | 197 | Q08632 | 271 | SDR1_PICAB Short-chain type dehydrogenase/red... | 266 | 0.00000000000002 | 75.1 | 30 | 43 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 198 | Q5HLD8 | 230 | Y2049_STAEQ Uncharacterized oxidoreductase SE... | 215 | 0.00000000000002 | 74.3 | 29 | 49 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 199 | Q8CN40 | 230 | Y2036_STAES Uncharacterized oxidoreductase SE... | 215 | 0.00000000000002 | 74.3 | 29 | 49 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 200 | Q9Y6Z9 | 255 | SOU1_SCHPO Sorbose reductase sou1 OS=Schizosa... | 195 | 0.00000000000003 | 74.7 | 34 | 48 | GO:0005739; C:mitochondrion; IDA:PomBase. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0032115; F:sorbose reductase activity; IEA:EC. | | | | | | | | | | GO:0005975; P:carbohydrate metabolic process; IEA:UniProtKB-KW. | 201 | Q9HBH5 | 336 | RDH14_HUMAN Retinol dehydrogenase 14 OS=Homo ... | 241 | 0.00000000000003 | 75.9 | 30 | 44 | GO:0005783; C:endoplasmic reticulum; IDA:LIFEdb. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 202 | P50205 | 241 | PHBB_RHIME Acetoacetyl-CoA reductase OS=melil... | 175 | 0.00000000000003 | 73.9 | 30 | 51 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0018454; F:acetoacetyl-CoA reductase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0042619; P:poly-hydroxybutyrate biosynthetic process; IEA:UniProtKB-KW. | 203 | O02691 | 261 | HCD2_BOVIN 3-hydroxyacyl-CoA dehydrogenase ty... | 216 | 0.00000000000004 | 73.9 | 29 | 45 | | | | | | | | | | | GO:0047015; F:3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity; IEA:EC.::GO:0003857; F:3-hydroxyacyl-CoA dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0008033; P:tRNA processing; IEA:UniProtKB-KW. | 204 | Q9X6U2 | 258 | BDHA_CUPNH D-beta-hydroxybutyrate dehydrogena... | 269 | 0.00000000000005 | 73.9 | 27 | 43 | | | | | | | | | | | GO:0003858; F:3-hydroxybutyrate dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | | 205 | P97852 | 735 | DHB4_RAT Peroxisomal multifunctional enzyme t... | 199 | 0.00000000000005 | 75.9 | 31 | 49 | GO:0005777; C:peroxisome; IDA:HGNC. | | | | | | | | | | GO:0033989; F:3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity; IEA:EC.::GO:0016853; F:isomerase activity; IEA:UniProtKB-KW.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0032934; F:sterol binding; IEA:InterPro.::GO:0030283; F:testosterone dehydrogenase [NAD(P) activity; TAS:RGD. | | | | | | | | | | GO:0008203; P:cholesterol metabolic process; NAS:RGD.::GO:0006631; P:fatty acid metabolic process; IEA:UniProtKB-KW.] | 206 | P50165 | 268 | TRNH_DATST Tropinone reductase homolog OS=Dat... | 261 | 0.00000000000007 | 73.6 | 26 | 46 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 207 | P19871 | 254 | 3BHD_COMTE 3-beta-hydroxysteroid dehydrogenas... | 257 | 0.00000000000007 | 73.2 | 30 | 45 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0030283; F:testosterone dehydrogenase [NAD(P) activity; IEA:EC. | | | | | | | | | | GO:0008202; P:steroid metabolic process; IEA:UniProtKB-KW.] | 208 | P50164 | 260 | TRN2_HYONI Tropinone reductase 2 OS=Hyoscyamu... | 272 | 0.00000000000007 | 73.2 | 29 | 44 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0050358; F:tropinone reductase activity; IEA:EC. | | | | | | | | | | | 209 | Q7Z4W1 | 244 | DCXR_HUMAN L-xylulose reductase OS=Homo sapie... | 261 | 0.0000000000001 | 72.8 | 28 | 45 | GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0050038; F:L-xylulose reductase (NADP+) activity; IDA:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016655; F:oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor; IDA:UniProtKB. | | | | | | | | | | GO:0042732; P:D-xylose metabolic process; IEA:UniProtKB-KW.::GO:0006006; P:glucose metabolic process; IDA:UniProtKB.::GO:0051289; P:protein homotetramerization; IDA:UniProtKB.::GO:0005997; P:xylulose metabolic process; IDA:UniProtKB. | 210 | Q99714 | 261 | HCD2_HUMAN 3-hydroxyacyl-CoA dehydrogenase ty... | 205 | 0.0000000000001 | 72.8 | 29 | 45 | GO:0005759; C:mitochondrial matrix; TAS:Reactome.::GO:0005886; C:plasma membrane; TAS:ProtInc. | | | | | | | | | | GO:0047015; F:3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity; IEA:EC.::GO:0003857; F:3-hydroxyacyl-CoA dehydrogenase activity; EXP:Reactome.::GO:0008709; F:cholate 7-alpha-dehydrogenase activity; TAS:ProtInc. | | | | | | | | | | GO:0009083; P:branched chain family amino acid catabolic process; TAS:Reactome.::GO:0006629; P:lipid metabolic process; TAS:ProtInc.::GO:0008033; P:tRNA processing; IEA:UniProtKB-KW. | 211 | P0A9P9 | 254 | IDNO_ECOLI Gluconate 5-dehydrogenase OS=Esche... | 260 | 0.0000000000001 | 72.8 | 27 | 44 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008874; F:gluconate 5-dehydrogenase activity; IDA:EcoCyc.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0019521; P:D-gluconate metabolic process; IEA:UniProtKB-KW.::GO:0046183; P:L-idonate catabolic process; IEP:EcoCyc. |