rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
61 | Q9Z1N3 | 2626 | MYO9A_RAT Unconventional myosin-IXa OS=Rattus... | 170 | 0.0000000001 | 69.7 | 28 | 47 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0016459; C:myosin complex; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0003774; F:motor activity; IEA:InterPro. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 62 | Q8SSN9 | 1140 | GACF_DICDI Rho GTPase-activating protein gacF... | 205 | 0.0000000002 | 69.3 | 27 | 43 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 63 | Q9P227 | 1491 | RHG23_HUMAN Rho GTPase-activating protein 23 ... | 204 | 0.0000000002 | 69.3 | 26 | 45 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 64 | B2RTY4 | 2548 | MYO9A_HUMAN Unconventional myosin-IXa OS=Homo... | 170 | 0.0000000002 | 69.3 | 28 | 47 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0016461; C:unconventional myosin complex; NAS:UniProtKB. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0003774; F:motor activity; IEA:InterPro. | | | | | | | | | | GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.::GO:0007601; P:visual perception; TAS:ProtInc. | 65 | Q07960 | 439 | RHG01_HUMAN Rho GTPase-activating protein 1 O... | 167 | 0.0000000002 | 67.8 | 31 | 50 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0043231; C:intracellular membrane-bounded organelle; IDA:HPA. | | | | | | | | | | GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW.::GO:0005070; F:SH3/SH2 adaptor activity; TAS:ProtInc. | | | | | | | | | | GO:0007266; P:Rho protein signal transduction; TAS:ProtInc. | 66 | Q6IFT4 | 1182 | RHG20_MOUSE Rho GTPase-activating protein 20 ... | 184 | 0.0000000002 | 68.9 | 29 | 45 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 67 | Q8N392 | 663 | RHG18_HUMAN Rho GTPase-activating protein 18 ... | 202 | 0.0000000002 | 68.6 | 24 | 46 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. | 68 | Q5ZMM3 | 475 | RHG15_CHICK Rho GTPase-activating protein 15 ... | 201 | 0.0000000002 | 68.2 | 27 | 49 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 69 | Q69ZH9 | 1483 | RHG23_MOUSE Rho GTPase-activating protein 23 ... | 204 | 0.0000000002 | 68.9 | 26 | 45 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 70 | Q5TG30 | 622 | RHG40_HUMAN Rho GTPase-activating protein 40 ... | 199 | 0.0000000002 | 68.2 | 27 | 44 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. | 71 | O14559 | 1287 | RHG33_HUMAN Rho GTPase-activating protein 33 ... | 214 | 0.0000000002 | 68.6 | 27 | 46 | | | | | | | | | | | GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007165; P:signal transduction; IEA:InterPro. | 72 | P11274 | 1271 | BCR_HUMAN Breakpoint cluster region protein O... | 198 | 0.0000000003 | 68.6 | 26 | 43 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; TAS:ProtInc.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. | 73 | Q54VW7 | 1203 | GACGG_DICDI Rho GTPase-activating protein gac... | 177 | 0.0000000003 | 68.2 | 29 | 48 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 74 | Q6PAJ1 | 1270 | BCR_MOUSE Breakpoint cluster region protein O... | 198 | 0.0000000004 | 68.2 | 26 | 43 | GO:0005829; C:cytosol; IDA:MGI.::GO:0005886; C:plasma membrane; IDA:MGI. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:MGI.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0030675; F:Rac GTPase activator activity; IGI:MGI.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0030036; P:actin cytoskeleton organization; IGI:MGI.::GO:0007420; P:brain development; IGI:MGI.::GO:0042472; P:inner ear morphogenesis; IGI:MGI.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0030336; P:negative regulation of cell migration; IGI:MGI.::GO:0050728; P:negative regulation of inflammatory response; IMP:MGI.::GO:0043314; P:negative regulation of neutrophil degranulation; IGI:MGI.::GO:0050885; P:neuromuscular process controlling balance; IGI:MGI.::GO:0050766; P:positive regulation of phagocytosis; IGI:MGI.::GO:0051726; P:regulation of cell cycle; IDA:MGI.::GO:0032496; P:response to lipopolysaccharide; IMP:MGI. | 75 | Q9P2N2 | 729 | RHG28_HUMAN Rho GTPase-activating protein 28 ... | 215 | 0.0000000005 | 67.4 | 25 | 40 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IDA:HPA. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. | 76 | Q54FG5 | 873 | GACJJ_DICDI Rho GTPase-activating protein gac... | 172 | 0.0000000006 | 67 | 27 | 48 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 77 | Q3KRB8 | 267 | RHGBB_HUMAN Rho GTPase-activating protein 11B... | 212 | 0.0000000007 | 64.7 | 29 | 47 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. | 78 | Q80YF9 | 1305 | RHG33_MOUSE Rho GTPase-activating protein 33 ... | 169 | 0.0000000007 | 67 | 28 | 47 | GO:0005737; C:cytoplasm; IDA:MGI.::GO:0005886; C:plasma membrane; IDA:MGI. | | | | | | | | | | GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.::GO:0030675; F:Rac GTPase activator activity; IDA:MGI. | | | | | | | | | | GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007165; P:signal transduction; IEA:InterPro. | 79 | O75044 | 1071 | FNBP2_HUMAN SLIT-ROBO Rho GTPase-activating p... | 199 | 0.0000000008 | 67 | 24 | 42 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007411; P:axon guidance; TAS:Reactome.::GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. | 80 | Q54YV1 | 817 | GACII_DICDI Rho GTPase-activating protein gac... | 154 | 0.0000000009 | 66.6 | 29 | 47 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 81 | P98171 | 946 | RHG04_HUMAN Rho GTPase-activating protein 4 O... | 187 | 0.000000001 | 66.6 | 30 | 41 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005925; C:focal adhesion; IDA:HPA.::GO:0005634; C:nucleus; IDA:HPA. | | | | | | | | | | GO:0005100; F:Rho GTPase activator activity; TAS:ProtInc.::GO:0005070; F:SH3/SH2 adaptor activity; TAS:ProtInc. | | | | | | | | | | GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0007010; P:cytoskeleton organization; TAS:ProtInc.::GO:0008624; P:induction of apoptosis by extracellular signals; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0007266; P:Rho protein signal transduction; TAS:ProtInc. | 82 | Q9NRY4 | 1513 | RHG35_HUMAN Rho GTPase-activating protein 35 ... | 166 | 0.000000001 | 66.6 | 23 | 48 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IC:UniProtKB. | | | | | | | | | | GO:0003677; F:DNA binding; TAS:ProtInc.::GO:0005525; F:GTP binding; IEA:InterPro.::GO:0005100; F:Rho GTPase activator activity; TAS:Reactome.::GO:0003714; F:transcription corepressor activity; TAS:ProtInc. | | | | | | | | | | GO:0007411; P:axon guidance; TAS:Reactome.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.::GO:0006351; P:transcription, DNA-dependent; TAS:ProtInc. | 83 | Q9VIS1 | 1843 | CDGAP_DROME GTPase-activating protein CdGAPr ... | 173 | 0.000000002 | 66.2 | 26 | 44 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0031290; P:retinal ganglion cell axon guidance; IMP:UniProtKB.::GO:0007165; P:signal transduction; IEA:InterPro. | 84 | Q03070 | 295 | CHIO_RAT Beta-chimaerin OS=Rattus norvegicus ... | 202 | 0.000000002 | 63.9 | 28 | 44 | GO:0005622; C:intracellular; IEA:InterPro.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0001565; F:phorbol ester receptor activity; TAS:RGD.::GO:0030675; F:Rac GTPase activator activity; IDA:RGD. | | | | | | | | | | GO:0001675; P:acrosome assembly; IEP:RGD.::GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 85 | P81128 | 1513 | RHG35_RAT Rho GTPase-activating protein 35 OS... | 166 | 0.000000002 | 66.2 | 23 | 48 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0005525; F:GTP binding; IEA:InterPro.::GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 86 | Q80XD1 | 332 | CHIO_MOUSE Beta-chimaerin OS=Mus musculus (Mo... | 202 | 0.000000002 | 64.3 | 28 | 44 | GO:0005622; C:intracellular; IEA:InterPro.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 87 | Q91YM2 | 1499 | RHG35_MOUSE Rho GTPase-activating protein 35 ... | 166 | 0.000000002 | 65.5 | 23 | 48 | GO:0015629; C:actin cytoskeleton; IDA:MGI.::GO:0005737; C:cytoplasm; IDA:MGI.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0005525; F:GTP binding; IEA:InterPro.::GO:0005096; F:GTPase activator activity; TAS:MGI. | | | | | | | | | | GO:0043010; P:camera-type eye development; IMP:MGI.::GO:0030900; P:forebrain development; IMP:MGI.::GO:0007229; P:integrin-mediated signaling pathway; TAS:MGI.::GO:0043116; P:negative regulation of vascular permeability; IMP:MGI.::GO:0001843; P:neural tube closure; IMP:MGI.::GO:0008360; P:regulation of cell shape; IDA:MGI.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 88 | P83509 | 1500 | RHG35_CANFA Rho GTPase-activating protein 35 ... | 166 | 0.000000002 | 65.5 | 23 | 48 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0005525; F:GTP binding; IEA:InterPro.::GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0042478; P:regulation of eye photoreceptor cell development; NAS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 89 | Q80Y19 | 987 | RHGBA_MOUSE Rho GTPase-activating protein 11A... | 197 | 0.000000003 | 65.1 | 27 | 45 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 90 | P32873 | 1128 | BEM3_YEAST GTPase-activating protein BEM3 OS=... | 222 | 0.000000003 | 65.1 | 27 | 42 | GO:0005938; C:cell cortex; IDA:SGD.::GO:0005934; C:cellular bud tip; IDA:SGD.::GO:0000131; C:incipient cellular bud site; IDA:SGD.::GO:0043332; C:mating projection tip; IDA:SGD. | | | | | | | | | | GO:0032266; F:phosphatidylinositol-3-phosphate binding; IDA:SGD.::GO:0005100; F:Rho GTPase activator activity; IDA:SGD. | | | | | | | | | | GO:0030010; P:establishment of cell polarity; TAS:SGD.::GO:0035024; P:negative regulation of Rho protein signal transduction; IMP:SGD.::GO:0007165; P:signal transduction; IEA:InterPro. | 91 | P34288 | 1605 | PAC1_CAEEL GTPase-activating protein pac-1 OS... | 213 | 0.000000003 | 65.1 | 23 | 45 | GO:0030054; C:cell junction; IDA:WormBase.::GO:0005737; C:cytoplasm; NAS:UniProtKB. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005100; F:Rho GTPase activator activity; IDA:UniProtKB. | | | | | | | | | | GO:0008105; P:asymmetric protein localization; IMP:WormBase.::GO:0010470; P:regulation of gastrulation; IMP:WormBase.::GO:0007266; P:Rho protein signal transduction; IDA:UniProtKB. |