Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Coccidiodis immitis RMSCC 2394
Locus:
CIRG_00164
Length:
696
Number of sequences:
10408
Description:
transforming growth factor beta 1
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P36166    706   PXL1_YEAST Paxillin-like protein 1 OS=Sacchar...1223e-23     108     36     54GO:0005935; C:cellular bud neck; IDA:SGD.::GO:0005934; C:cellular bud tip; IDA:SGD.::GO:0005737; C:cytoplasm; IDA:SGD.::GO:0000131; C:incipient cellular bud site; IDA:SGD.::GO:0043332; C:mating projection tip; IDA:SGD.
GO:0005094; F:Rho GDP-dissociation inhibitor activity; IGI:SGD.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030011; P:maintenance of cell polarity; IMP:SGD.::GO:0035023; P:regulation of Rho protein signal transduction; IPI:SGD.
2Q8VI36    591   PAXI_MOUSE Paxillin OS=Mus musculus (Mouse). ...1250.0002     48.5     24     40GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IDA:MGI.::GO:0030027; C:lamellipodium; IDA:MGI.
GO:0051435; F:BH4 domain binding; IPI:MGI.::GO:0030159; F:receptor signaling complex scaffold activity; TAS:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0000187; P:activation of MAPK activity; IDA:MGI.::GO:0048754; P:branching morphogenesis of a tube; IDA:MGI.::GO:0006928; P:cellular component movement; IMP:MGI.::GO:0007010; P:cytoskeleton organization; IMP:MGI.::GO:0048041; P:focal adhesion assembly; IDA:MGI.::GO:0007229; P:integrin-mediated signaling pathway; IMP:MGI.::GO:0030032; P:lamellipodium assembly; IDA:MGI.::GO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:MGI.
3P49023    591   PAXI_HUMAN Paxillin OS=Homo sapiens (Human). ...1250.0005     47     24     40GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IDA:BHF-UCL.::GO:0030027; C:lamellipodium; IDA:BHF-UCL.::GO:0005875; C:microtubule associated complex; TAS:ProtInc.
GO:0008013; F:beta-catenin binding; IPI:UniProtKB.::GO:0017166; F:vinculin binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0034614; P:cellular response to reactive oxygen species; IEP:BHF-UCL.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0060396; P:growth hormone receptor signaling pathway; IDA:BHF-UCL.::GO:0006936; P:muscle contraction; TAS:Reactome.::GO:0007172; P:signal complex assembly; TAS:ProtInc.
4P49024    559   PAXI_CHICK Paxillin OS=Gallus gallus (Chicken...1250.0004     47     24     39GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007160; P:cell-matrix adhesion; IEA:InterPro.
5Q5R7I1    591   PAXI_PONAB Paxillin OS=Pongo abelii (Sumatran...1250.0006     47     24     40GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007160; P:cell-matrix adhesion; IEA:InterPro.
6Q66H76    586   PAXI_RAT Paxillin OS=Rattus norvegicus (Rat)....1250.0006     46.6     24     40GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IDA:RGD.
GO:0005178; F:integrin binding; IPI:RGD.::GO:0019901; F:protein kinase binding; IPI:RGD.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007160; P:cell-matrix adhesion; IEA:InterPro.
7Q3MHZ4    456   TGFI1_BOVIN Transforming growth factor beta-1...1320.075     39.7     30     39GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.::GO:0016363; C:nuclear matrix; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
8O43294    461   TGFI1_HUMAN Transforming growth factor beta-1...1320.08     39.7     30     39GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.::GO:0016363; C:nuclear matrix; IEA:UniProtKB-SubCell.
GO:0050681; F:androgen receptor binding; IPI:UniProtKB.::GO:0070411; F:I-SMAD binding; IPI:BHF-UCL.::GO:0048495; F:Roundabout binding; IPI:UniProtKB.::GO:0003713; F:transcription coactivator activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030521; P:androgen receptor signaling pathway; NAS:UniProtKB.::GO:0007155; P:cell adhesion; TAS:ProtInc.::GO:0008285; P:negative regulation of cell proliferation; TAS:ProtInc.::GO:0030512; P:negative regulation of transforming growth factor beta receptor signaling pathway; IDA:BHF-UCL.::GO:0010718; P:positive regulation of epithelial to mesenchymal transition; IDA:BHF-UCL.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0030511; P:positive regulation of transforming growth factor beta receptor signaling pathway; IDA:BHF-UCL.::GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.::GO:0030579; P:ubiquitin-dependent SMAD protein catabolic process; IDA:BHF-UCL.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
9Q2TCH4    506   TGFI1_XENLA Transforming growth factor beta-1...1070.0003     47.4     26     40GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.::GO:0016363; C:nuclear matrix; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
10Q62219    461   TGFI1_MOUSE Transforming growth factor beta-1...1320.04     40.8     29     39GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IDA:MGI.::GO:0016363; C:nuclear matrix; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0045165; P:cell fate commitment; IGI:MGI.::GO:0030855; P:epithelial cell differentiation; IGI:MGI.::GO:0016331; P:morphogenesis of embryonic epithelium; IMP:MGI.::GO:0045599; P:negative regulation of fat cell differentiation; IGI:MGI.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
11O60711    386   LPXN_HUMAN Leupaxin OS=Homo sapiens (Human). ...1252.4     35     22     38GO:0042995; C:cell projection; IEA:UniProtKB-KW.::GO:0005925; C:focal adhesion; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0002102; C:podosome; IDA:UniProtKB.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0003712; F:transcription cofactor activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007155; P:cell adhesion; NAS:ProtInc.::GO:0050859; P:negative regulation of B cell receptor signaling pathway; IDA:UniProtKB.::GO:0007162; P:negative regulation of cell adhesion; IDA:UniProtKB.::GO:0006461; P:protein complex assembly; TAS:ProtInc.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0007165; P:signal transduction; TAS:ProtInc.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
12Q99PD6    461   TGFI1_RAT Transforming growth factor beta-1-i...1320.052     40.4     29     39GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; TAS:RGD.::GO:0016363; C:nuclear matrix; IEA:UniProtKB-SubCell.
GO:0070411; F:I-SMAD binding; IPI:BHF-UCL.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0009408; P:response to heat; IDA:RGD.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
13Q09476    413   PXL1_CAEEL Paxillin homolog 1 OS=Caenorhabdit...1260.000004     53.5     29     41GO:0005912; C:adherens junction; IDA:WormBase.::GO:0031430; C:M band; IDA:WormBase.::GO:0002102; C:podosome; IDA:WormBase.::GO:0055120; C:striated muscle dense body; IDA:WormBase.
GO:0017166; F:vinculin binding; IPI:WormBase.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040007; P:growth; IMP:WormBase.::GO:0061061; P:muscle structure development; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0043050; P:pharyngeal pumping; IMP:WormBase.::GO:0040010; P:positive regulation of growth rate; IMP:WormBase.
14Q8MML5    569   PAXB_DICDI Paxillin-B OS=Dictyostelium discoi...590.31     38.1     31     49GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0032433; C:filopodium tip; IDA:dictyBase.::GO:0005925; C:focal adhesion; IDA:dictyBase.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0016339; P:calcium-dependent cell-cell adhesion; IMP:dictyBase.::GO:0016477; P:cell migration; IMP:dictyBase.::GO:0031589; P:cell-substrate adhesion; IMP:dictyBase.::GO:0043326; P:chemotaxis to folate; IMP:dictyBase.::GO:0031154; P:culmination involved in sorocarp development; IMP:dictyBase.::GO:0007109; P:cytokinesis, completion of separation; IMP:dictyBase.
15A1Z6W3    1299   PRIC1_DROME Protein prickle OS=Drosophila mel...1250.000008     53.1     26     41GO:0005737; C:cytoplasm; TAS:FlyBase.::GO:0005886; C:plasma membrane; IDA:UniProtKB.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0009948; P:anterior/posterior axis specification; IMP:UniProtKB.::GO:0001737; P:establishment of imaginal disc-derived wing hair orientation; IMP:FlyBase.::GO:0042067; P:establishment of ommatidial planar polarity; IMP:FlyBase.::GO:0045184; P:establishment of protein localization; TAS:FlyBase.::GO:0045185; P:maintenance of protein location; TAS:FlyBase.
16Q6H8Q1    611   ABLM2_HUMAN Actin-binding LIM protein 2 OS=Ho...1120.00009     49.3     29     42GO:0015629; C:actin cytoskeleton; IDA:MGI.::GO:0005737; C:cytoplasm; IDA:HPA.::GO:0045111; C:intermediate filament cytoskeleton; IDA:HPA.::GO:0005634; C:nucleus; IDA:HPA.
GO:0003779; F:actin binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007411; P:axon guidance; TAS:Reactome.::GO:0007010; P:cytoskeleton organization; IEA:InterPro.
17O14639    778   ABLM1_HUMAN Actin-binding LIM protein 1 OS=Ho...1610.000002     55.1     27     41GO:0015629; C:actin cytoskeleton; TAS:ProtInc.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; TAS:ProtInc.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007411; P:axon guidance; TAS:Reactome.::GO:0007010; P:cytoskeleton organization; IEA:InterPro.::GO:0009887; P:organ morphogenesis; TAS:ProtInc.::GO:0007601; P:visual perception; TAS:ProtInc.
18Q8K4G5    861   ABLM1_MOUSE Actin-binding LIM protein 1 OS=Mu...1120.0000006     56.6     29     46GO:0015629; C:actin cytoskeleton; IDA:MGI.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; IDA:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007411; P:axon guidance; IDA:MGI.::GO:0007010; P:cytoskeleton organization; IEA:InterPro.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:MGI.
19Q292U2    1353   PRIC1_DROPS Protein prickle OS=Drosophila pse...1250.000003     54.3     27     41GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0009948; P:anterior/posterior axis specification; ISS:UniProtKB.::GO:0001736; P:establishment of planar polarity; ISS:UniProtKB.
20Q8BL65    612   ABLM2_MOUSE Actin-binding LIM protein 2 OS=Mu...1290.0003     47.8     29     43GO:0030016; C:myofibril; IDA:MGI.
GO:0003779; F:actin binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007010; P:cytoskeleton organization; IEA:InterPro.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:MGI.
21Q54NW4    553   LIMB_DICDI LIM domain-containing protein B OS...663.9     34.3     29     45GO:0005938; C:cell cortex; IDA:dictyBase.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; ISS:dictyBase.
GO:0031152; P:aggregation involved in sorocarp development; IMP:dictyBase.::GO:0007155; P:cell adhesion; IMP:dictyBase.::GO:0006935; P:chemotaxis; IMP:dictyBase.::GO:0031154; P:culmination involved in sorocarp development; IMP:dictyBase.
22O75112    727   LDB3_HUMAN LIM domain-binding protein 3 OS=Ho...630.0002     48.5     32     43GO:0005856; C:cytoskeleton; IDA:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0031143; C:pseudopodium; IEA:UniProtKB-SubCell.::GO:0030018; C:Z disc; IEA:UniProtKB-SubCell.
GO:0008092; F:cytoskeletal protein binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
23Q99N69    386   LPXN_MOUSE Leupaxin OS=Mus musculus (Mouse). ...1260.048     40.4     27     40GO:0042995; C:cell projection; IEA:UniProtKB-KW.::GO:0005925; C:focal adhesion; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0002102; C:podosome; IDA:UniProtKB.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0003712; F:transcription cofactor activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0050859; P:negative regulation of B cell receptor signaling pathway; IDA:UniProtKB.::GO:0033628; P:regulation of cell adhesion mediated by integrin; IMP:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
24Q6KC51    612   ABLM2_RAT Actin-binding LIM protein 2 OS=Ratt...1290.0005     47     29     43GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007010; P:cytoskeleton organization; IEA:InterPro.
25Q9JKS4    723   LDB3_MOUSE LIM domain-binding protein 3 OS=Mu...630.0003     48.1     32     43GO:0005856; C:cytoskeleton; ISS:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0031143; C:pseudopodium; IEA:UniProtKB-SubCell.::GO:0030018; C:Z disc; IDA:MGI.
GO:0005080; F:protein kinase C binding; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
26Q9N261    386   LPXN_RABIT Leupaxin OS=Oryctolagus cuniculus ...1061.9     35     25     40GO:0042995; C:cell projection; IEA:UniProtKB-KW.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0002102; C:podosome; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
27Q96HC4    596   PDLI5_HUMAN PDZ and LIM domain protein 5 OS=H...370.02     42     35     49GO:0015629; C:actin cytoskeleton; IDA:LIFEdb.::GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.::GO:0014069; C:postsynaptic density; ISS:UniProtKB.::GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-KW.::GO:0019717; C:synaptosome; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; ISS:UniProtKB.::GO:0042805; F:actinin binding; ISS:UniProtKB.::GO:0005080; F:protein kinase C binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0061001; P:regulation of dendritic spine morphogenesis; ISS:UniProtKB.::GO:0051963; P:regulation of synapse assembly; ISS:UniProtKB.
28O43052    1150   RGA1_SCHPO Rho-type GTPase-activating protein...1290.00000003     60.8     30     43GO:0032153; C:cell division site; IDA:PomBase.::GO:0030428; C:cell septum; IEA:UniProtKB-SubCell.::GO:0051286; C:cell tip; IDA:PomBase.::GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
GO:0005100; F:Rho GTPase activator activity; ISS:PomBase.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0051666; P:actin cortical patch localization; IMP:PomBase.::GO:0030036; P:actin cytoskeleton organization; IMP:PomBase.::GO:0071937; P:barrier septum assembly involved in cell cycle cytokinesis; IMP:PomBase.::GO:0009272; P:fungal-type cell wall biogenesis; IMP:PomBase.::GO:0008360; P:regulation of cell shape; IMP:PomBase.::GO:0007165; P:signal transduction; IEA:InterPro.
29Q174I2    916   PRIC1_AEDAE Protein prickle OS=Aedes aegypti ...1260.00005     50.4     28     40GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0009948; P:anterior/posterior axis specification; ISS:UniProtKB.::GO:0001736; P:establishment of planar polarity; ISS:UniProtKB.
30Q9VY77    728   AJUBA_DROME LIM domain-containing protein jub...1550.000001     55.5     28     38GO:0005912; C:adherens junction; IDA:FlyBase.
GO:0003779; F:actin binding; ISS:FlyBase.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0035329; P:hippo signaling cascade; IMP:FlyBase.::GO:0045572; P:positive regulation of imaginal disc growth; IMP:FlyBase.
31Q96A47    359   ISL2_HUMAN Insulin gene enhancer protein ISL-...1780.00000008     58.5     27     40GO:0005634; C:nucleus; IC:BHF-UCL.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0048935; P:peripheral nervous system neuron development; TAS:BHF-UCL.
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