| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
121 | Q9QUS4 | 339 | HEY2_MOUSE Hairy/enhancer-of-split related wi... | 102 | 2.2 | 35.4 | 26 | 43 | GO:0005737; C:cytoplasm; IDA:UniProtKB. | | | | | | | | | | GO:0035939; F:microsatellite binding; IDA:UniProtKB.::GO:0000988; F:protein binding transcription factor activity; IDA:UniProtKB.::GO:0000983; F:RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity; IDA:UniProtKB. | | | | | | | | | | GO:0009948; P:anterior/posterior axis specification; IGI:MGI.::GO:0060840; P:artery development; IGI:MGI.::GO:0003171; P:atrioventricular valve development; IMP:MGI.::GO:0014898; P:cardiac muscle hypertrophy in response to stress; IDA:MGI.::GO:0060948; P:cardiac vascular smooth muscle cell development; IMP:MGI.::GO:0045165; P:cell fate commitment; IMP:MGI.::GO:0090102; P:cochlea development; IMP:MGI.::GO:0060977; P:coronary vasculature morphogenesis; IMP:MGI.::GO:0003199; P:endocardial cushion to mesenchymal transition involved in heart valve formation; IGI:MGI.::GO:0010667; P:negative regulation of cardiac muscle cell apoptotic process; IMP:MGI.::GO:0045746; P:negative regulation of Notch signaling pathway; IMP:UniProtKB.::GO:2000820; P:negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation; IDA:BHF-UCL.::GO:2000678; P:negative regulation of transcription regulatory region DNA binding; IDA:BHF-UCL.::GO:0007219; P:Notch signaling pathway; IDA:UniProtKB.::GO:0060045; P:positive regulation of cardiac muscle cell proliferation; IMP:MGI.::GO:0010460; P:positive regulation of heart rate; IMP:MGI.::GO:0045747; P:positive regulation of Notch signaling pathway; TAS:BHF-UCL.::GO:0065004; P:protein-DNA complex assembly; IDA:MGI.::GO:0045607; P:regulation of auditory receptor cell differentiation; IGI:MGI.::GO:0003195; P:tricuspid valve formation; IMP:MGI.::GO:0001570; P:vasculogenesis; IGI:MGI.::GO:0055015; P:ventricular cardiac muscle cell development; IMP:BHF-UCL.::GO:0003222; P:ventricular trabecula myocardium morphogenesis; IGI:MGI. | 122 | Q9NQ87 | 328 | HEYL_HUMAN Hairy/enhancer-of-split related wi... | 101 | 2.3 | 35.4 | 28 | 46 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB. | | | | | | | | | | GO:0050683; F:AF-1 domain binding; IPI:UniProtKB.::GO:0035939; F:microsatellite binding; IDA:UniProtKB.::GO:0046982; F:protein heterodimerization activity; IDA:UniProtKB.::GO:0000983; F:RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity; ISS:UniProtKB.::GO:0008134; F:transcription factor binding; NAS:UniProtKB. | | | | | | | | | | GO:0003198; P:epithelial to mesenchymal transition involved in endocardial cushion formation; ISS:UniProtKB.::GO:2000824; P:negative regulation of androgen receptor activity; IDA:UniProtKB.::GO:0060766; P:negative regulation of androgen receptor signaling pathway; IDA:UniProtKB.::GO:0007219; P:Notch signaling pathway; IDA:UniProtKB.::GO:0045666; P:positive regulation of neuron differentiation; ISS:UniProtKB. | 123 | Q7XHI7 | 307 | BH127_ARATH Transcription factor bHLH127 OS=A... | 84 | 2.3 | 35.4 | 29 | 42 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 124 | Q2NL18 | 328 | HEYL_BOVIN Hairy/enhancer-of-split related wi... | 100 | 2.8 | 35 | 28 | 45 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0007219; P:Notch signaling pathway; IEA:UniProtKB-KW. | 125 | Q39204 | 623 | RAP1_ARATH Transcription factor MYC2 OS=Arabi... | 94 | 3.5 | 35 | 24 | 45 | GO:0005634; C:nucleus; IDA:TAIR. | | | | | | | | | | GO:0003677; F:DNA binding; IDA:TAIR.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0009738; P:abscisic acid mediated signaling pathway; IEA:UniProtKB-KW.::GO:0009963; P:positive regulation of flavonoid biosynthetic process; IEP:TAIR.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:TAIR.::GO:2000068; P:regulation of defense response to insect; IMP:TAIR.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IMP:TAIR.::GO:0043619; P:regulation of transcription from RNA polymerase II promoter in response to oxidative stress; IMP:TAIR.::GO:0010200; P:response to chitin; IEP:TAIR.::GO:0009269; P:response to desiccation; IEP:TAIR.::GO:0009753; P:response to jasmonic acid stimulus; IMP:TAIR.::GO:0009611; P:response to wounding; IEP:TAIR.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 126 | Q62912 | 206 | MAD3_RAT Max dimerization protein 3 OS=Rattus... | 48 | 3.9 | 34.3 | 40 | 54 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 127 | O08789 | 591 | MNT_MOUSE Max-binding protein MNT OS=Mus musc... | 136 | 4.7 | 34.7 | 26 | 38 | GO:0005634; C:nucleus; IC:MGI. | | | | | | | | | | GO:0003682; F:chromatin binding; IDA:MGI.::GO:0003677; F:DNA binding; IDA:MGI.::GO:0005515; F:protein binding; IPI:MGI.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IMP:MGI. | | | | | | | | | | GO:0007569; P:cell aging; IMP:MGI.::GO:0042981; P:regulation of apoptotic process; IMP:MGI.::GO:0051726; P:regulation of cell cycle; IMP:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 128 | Q9ERS6 | 686 | IRPL2_MOUSE X-linked interleukin-1 receptor a... | 87 | 4.7 | 34.7 | 31 | 45 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0004910; F:interleukin-1, Type II, blocking receptor activity; IEA:InterPro. | | | | | | | | | | GO:0045087; P:innate immune response; IEA:InterPro. | 129 | P24793 | 437 | MYCN_XENLA N-myc protein OS=Xenopus laevis (A... | 75 | 5 | 34.7 | 28 | 41 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro. | | | | | | | | | | | 130 | Q14582 | 209 | MAD4_HUMAN Max dimerization protein 4 OS=Homo... | 105 | 5.4 | 33.9 | 29 | 45 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003714; F:transcription corepressor activity; TAS:ProtInc. | | | | | | | | | | GO:0008285; P:negative regulation of cell proliferation; TAS:ProtInc.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 131 | Q99583 | 582 | MNT_HUMAN Max-binding protein MNT OS=Homo sap... | 136 | 6.3 | 34.3 | 26 | 38 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.::GO:0003713; F:transcription coactivator activity; TAS:ProtInc.::GO:0003714; F:transcription corepressor activity; TAS:ProtInc. | | | | | | | | | | GO:0007275; P:multicellular organismal development; TAS:ProtInc.::GO:0008285; P:negative regulation of cell proliferation; TAS:ProtInc.::GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc. | 132 | Q9I9L0 | 324 | HEY2_DANRE Hairy/enhancer-of-split related wi... | 86 | 6.3 | 33.9 | 28 | 43 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:ZFIN. | | | | | | | | | | GO:0035912; P:dorsal aorta morphogenesis; IMP:ZFIN.::GO:0007507; P:heart development; IMP:ZFIN.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IGI:ZFIN.::GO:0060853; P:Notch signaling pathway involved in arterial endothelial cell fate commitment; IMP:ZFIN.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0001570; P:vasculogenesis; IMP:ZFIN. | 133 | Q9UBP5 | 337 | HEY2_HUMAN Hairy/enhancer-of-split related wi... | 86 | 7.1 | 33.9 | 28 | 43 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0017053; C:transcriptional repressor complex; IDA:BHF-UCL. | | | | | | | | | | GO:0042826; F:histone deacetylase binding; IPI:BHF-UCL.::GO:0035939; F:microsatellite binding; IDA:UniProtKB.::GO:0000988; F:protein binding transcription factor activity; IDA:UniProtKB.::GO:0001102; F:RNA polymerase II activating transcription factor binding; IPI:BHF-UCL.::GO:0000983; F:RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity; ISS:UniProtKB. | | | | | | | | | | GO:2000723; P:negative regulation of cardiac vascular smooth muscle cell differentiation; ISS:BHF-UCL.::GO:0010621; P:negative regulation of transcription by transcription factor localization; ISS:BHF-UCL.::GO:2000820; P:negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation; ISS:BHF-UCL.::GO:0060633; P:negative regulation of transcription initiation from RNA polymerase II promoter; IDA:BHF-UCL.::GO:2000678; P:negative regulation of transcription regulatory region DNA binding; IDA:BHF-UCL.::GO:0007219; P:Notch signaling pathway; ISS:UniProtKB.::GO:0055015; P:ventricular cardiac muscle cell development; ISS:UniProtKB. | 134 | P38165 | 486 | RTG3_YEAST Retrograde regulation protein 3 OS... | 94 | 7.1 | 34.3 | 29 | 44 | GO:0005737; C:cytoplasm; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD. | | | | | | | | | | GO:0001085; F:RNA polymerase II transcription factor binding; IPI:SGD.::GO:0043565; F:sequence-specific DNA binding; IDA:SGD.::GO:0000981; F:sequence-specific DNA binding RNA polymerase II transcription factor activity; IDA:SGD. | | | | | | | | | | GO:0071400; P:cellular response to oleic acid; IMP:SGD.::GO:0031930; P:mitochondria-nucleus signaling pathway; IDA:SGD.::GO:0000422; P:mitochondrion degradation; IMP:SGD.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:SGD.::GO:0042991; P:transcription factor import into nucleus; IMP:SGD. | 135 | P43062 | 465 | CG12_CANAX G1/S-specific cyclin CLN2 OS=Candi... | 67 | 7.2 | 33.9 | 34 | 54 | | | | | | | | | | | | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW. | 136 | Q9DBX7 | 326 | HEYL_MOUSE Hairy/enhancer-of-split related wi... | 87 | 8.2 | 33.5 | 25 | 45 | GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005654; C:nucleoplasm; TAS:Reactome. | | | | | | | | | | GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.::GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IDA:UniProtKB.::GO:0000979; F:RNA polymerase II core promoter sequence-specific DNA binding; IDA:UniProtKB.::GO:0000983; F:RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.::GO:0001106; F:RNA polymerase II transcription corepressor activity; IDA:UniProtKB. | | | | | | | | | | GO:0071773; P:cellular response to BMP stimulus; IEP:UniProtKB.::GO:0003198; P:epithelial to mesenchymal transition involved in endocardial cushion formation; IGI:MGI.::GO:0032835; P:glomerulus development; IEP:UniProtKB.::GO:2000824; P:negative regulation of androgen receptor activity; ISS:UniProtKB.::GO:0060766; P:negative regulation of androgen receptor signaling pathway; ISS:UniProtKB.::GO:0007219; P:Notch signaling pathway; ISS:UniProtKB.::GO:0007422; P:peripheral nervous system development; NAS:UniProtKB.::GO:0045666; P:positive regulation of neuron differentiation; IDA:UniProtKB.::GO:0072014; P:proximal tubule development; IEP:UniProtKB. | 137 | P49379 | 359 | CBF1_KLULA Centromere-binding protein 1 OS=12... | 75 | 8.9 | 33.5 | 28 | 44 | GO:0000775; C:chromosome, centromeric region; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW. | | | | | | | | | | | 138 | Q7KM13 | 425 | HEY_DROME Hairy/enhancer-of-split related wit... | 91 | 9 | 33.9 | 29 | 45 | GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0003677; F:DNA binding; ISS:UniProtKB. | | | | | | | | | | GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0045746; P:negative regulation of Notch signaling pathway; ISS:UniProtKB.::GO:0007219; P:Notch signaling pathway; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. |
