Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Coccidiodis immitis RMSCC 2394
Locus:
CIRG_00096
Length:
322
Number of sequences:
10408
Description:
glutamate-cysteine ligase modifier subunit
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P48508    274   GSH0_RAT Glutamate--cysteine ligase regulator...2162e-23     101     29     52GO:0017109; C:glutamate-cysteine ligase complex; IDA:RGD.::GO:0005625; C:soluble fraction; ISS:UniProtKB.
GO:0004357; F:glutamate-cysteine ligase activity; IDA:RGD.::GO:0035226; F:glutamate-cysteine ligase catalytic subunit binding; ISS:UniProtKB.::GO:0046982; F:protein heterodimerization activity; IDA:RGD.
GO:0006536; P:glutamate metabolic process; ISS:UniProtKB.::GO:0006750; P:glutathione biosynthetic process; ISS:UniProtKB.::GO:0043524; P:negative regulation of neuron apoptotic process; IMP:RGD.::GO:0035229; P:positive regulation of glutamate-cysteine ligase activity; IDA:RGD.::GO:0050880; P:regulation of blood vessel size; ISS:UniProtKB.::GO:0042493; P:response to drug; ISS:UniProtKB.::GO:0051409; P:response to nitrosative stress; IMP:RGD.::GO:0006979; P:response to oxidative stress; ISS:UniProtKB.
2Q2T9Y6    274   GSH0_BOVIN Glutamate--cysteine ligase regulat...2167e-23     99.8     28     52GO:0005625; C:soluble fraction; ISS:UniProtKB.
GO:0035226; F:glutamate-cysteine ligase catalytic subunit binding; ISS:UniProtKB.
GO:0006536; P:glutamate metabolic process; ISS:UniProtKB.::GO:0006750; P:glutathione biosynthetic process; ISS:UniProtKB.::GO:0050880; P:regulation of blood vessel size; ISS:UniProtKB.::GO:0042493; P:response to drug; ISS:UniProtKB.::GO:0006979; P:response to oxidative stress; ISS:UniProtKB.
3O09172    274   GSH0_MOUSE Glutamate--cysteine ligase regulat...2162e-22     98.6     29     53GO:0017109; C:glutamate-cysteine ligase complex; IDA:MGI.::GO:0005625; C:soluble fraction; ISS:UniProtKB.
GO:0035226; F:glutamate-cysteine ligase catalytic subunit binding; ISS:UniProtKB.::GO:0046982; F:protein heterodimerization activity; IPI:MGI.
GO:0006534; P:cysteine metabolic process; IMP:MGI.::GO:0006536; P:glutamate metabolic process; ISS:UniProtKB.::GO:0006750; P:glutathione biosynthetic process; ISS:UniProtKB.::GO:0035229; P:positive regulation of glutamate-cysteine ligase activity; IDA:MGI.::GO:0050880; P:regulation of blood vessel size; ISS:UniProtKB.::GO:0051900; P:regulation of mitochondrial depolarization; IGI:MGI.::GO:0042493; P:response to drug; ISS:UniProtKB.::GO:0006979; P:response to oxidative stress; ISS:UniProtKB.
4P48507    274   GSH0_HUMAN Glutamate--cysteine ligase regulat...2168e-22     96.7     29     53GO:0005829; C:cytosol; NAS:UniProtKB.::GO:0005625; C:soluble fraction; IDA:UniProtKB.
GO:0035226; F:glutamate-cysteine ligase catalytic subunit binding; IPI:UniProtKB.
GO:0006536; P:glutamate metabolic process; IDA:UniProtKB.::GO:0006750; P:glutathione biosynthetic process; IDA:UniProtKB.::GO:0050880; P:regulation of blood vessel size; IMP:UniProtKB.::GO:0042493; P:response to drug; IDA:UniProtKB.::GO:0006979; P:response to oxidative stress; IDA:UniProtKB.::GO:0006805; P:xenobiotic metabolic process; TAS:Reactome.
5O94246    287   GSH0_SCHPO Putative glutamate--cysteine ligas...2193e-18     86.3     26     46GO:0005829; C:cytosol; IDA:PomBase.::GO:0017109; C:glutamate-cysteine ligase complex; ISS:PomBase.
GO:0030234; F:enzyme regulator activity; ISS:PomBase.::GO:0035226; F:glutamate-cysteine ligase catalytic subunit binding; ISS:PomBase.
GO:0006750; P:glutathione biosynthetic process; IEA:UniProtKB-KW.::GO:0035229; P:positive regulation of glutamate-cysteine ligase activity; ISS:PomBase.
6Q6IMN8    297   ALRA_DICDI Aldose reductase A OS=Dictyosteliu...1530.0000002     55.5     25     49GO:0005829; C:cytosol; IDA:dictyBase.::GO:0005615; C:extracellular space; IDA:dictyBase.::GO:0045335; C:phagocytic vesicle; IDA:dictyBase.
GO:0004032; F:alditol:NADP+ 1-oxidoreductase activity; IDA:dictyBase.
GO:0006928; P:cellular component movement; IMP:dictyBase.::GO:0042593; P:glucose homeostasis; IMP:dictyBase.::GO:0031158; P:negative regulation of aggregate size involved in sorocarp development; IMP:dictyBase.::GO:0009617; P:response to bacterium; IEP:dictyBase.::GO:0006979; P:response to oxidative stress; IMP:dictyBase.
7Q10494    321   YDG7_SCHPO Uncharacterized oxidoreductase C26...990.000003     52     27     54GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
GO:0047935; F:glucose 1-dehydrogenase (NADP+) activity; ISS:PomBase.
GO:0019568; P:arabinose catabolic process; ISS:PomBase.::GO:0033554; P:cellular response to stress; IEP:PomBase.::GO:0042843; P:D-xylose catabolic process; ISS:PomBase.
8Q3ZCJ2    325   AK1A1_BOVIN Alcohol dehydrogenase [NADP(+)] O...1190.000004     51.6     24     50
9Q8X195    321   XYL1_CANBO NADPH-dependent D-xylose reductase...1250.000004     51.2     32     52
GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
GO:0042732; P:D-xylose metabolic process; IEA:UniProtKB-KW.
10P27800    323   ALDX_SPOSA Aldehyde reductase 1 OS=Sporobolom...1340.000006     50.8     26     51GO:0005623; C:cell; IDA:UniProtKB.
GO:0008106; F:alcohol dehydrogenase (NADP+) activity; IDA:UniProtKB.
11O94735    317   XYL1_PICGU NADPH-dependent D-xylose reductase...1260.000008     50.4     31     49
GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
GO:0042732; P:D-xylose metabolic process; IEA:UniProtKB-KW.
12Q8VCX1    325   AK1D1_MOUSE 3-oxo-5-beta-steroid 4-dehydrogen...1370.000009     50.4     28     49
GO:0047787; F:delta4-3-oxosteroid 5beta-reductase activity; IEA:EC.
GO:0030573; P:bile acid catabolic process; IEA:UniProtKB-KW.
13O70473    228   AK1A1_CRIGR Alcohol dehydrogenase [NADP(+)] O...1460.00001     49.3     23     48
GO:0008106; F:alcohol dehydrogenase (NADP+) activity; IEA:EC.
14Q9TV64    326   AK1D1_RABIT 3-oxo-5-beta-steroid 4-dehydrogen...1320.00002     49.3     29     49
GO:0047787; F:delta4-3-oxosteroid 5beta-reductase activity; IEA:EC.
GO:0030573; P:bile acid catabolic process; IEA:UniProtKB-KW.
15P51635    325   AK1A1_RAT Alcohol dehydrogenase [NADP(+)] OS=...1520.00002     49.3     22     47
16Q0CUL0    320   XYL1_ASPTN Probable NAD(P)H-dependent D-xylos...1210.00002     49.3     29     47
GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
GO:0042732; P:D-xylose metabolic process; IEA:UniProtKB-KW.
17Q54NZ7    311   ALRB_DICDI Aldose reductase B OS=Dictyosteliu...1080.00002     49.3     28     54
GO:0004032; F:alditol:NADP+ 1-oxidoreductase activity; ISS:dictyBase.
18Q9JII6    325   AK1A1_MOUSE Alcohol dehydrogenase [NADP(+)] O...1250.00002     48.9     26     47GO:0016324; C:apical plasma membrane; IDA:MGI.::GO:0005829; C:cytosol; IDA:MGI.
GO:0004032; F:alditol:NADP+ 1-oxidoreductase activity; IDA:MGI.::GO:0047939; F:L-glucuronate reductase activity; IDA:MGI.
GO:0046185; P:aldehyde catabolic process; IDA:MGI.::GO:0042840; P:D-glucuronate catabolic process; IDA:MGI.::GO:0019853; P:L-ascorbic acid biosynthetic process; IDA:MGI.
19Q55FL3    321   ALRC_DICDI Aldose reductase C OS=Dictyosteliu...1160.00003     48.9     27     53
GO:0004032; F:alditol:NADP+ 1-oxidoreductase activity; ISS:dictyBase.
GO:0005975; P:carbohydrate metabolic process; ISS:dictyBase.
20Q7G765    322   NADO2_ORYSJ Probable NAD(P)H-dependent oxidor...1300.00003     48.5     25     46
GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
21P51857    326   AK1D1_HUMAN 3-oxo-5-beta-steroid 4-dehydrogen...1320.00003     48.5     27     51GO:0005829; C:cytosol; IDA:UniProtKB.
GO:0047787; F:delta4-3-oxosteroid 5beta-reductase activity; IEA:EC.::GO:0005496; F:steroid binding; TAS:UniProtKB.
GO:0008209; P:androgen metabolic process; IDA:UniProtKB.::GO:0006699; P:bile acid biosynthetic process; IDA:UniProtKB.::GO:0030573; P:bile acid catabolic process; IEA:UniProtKB-KW.::GO:0008207; P:C21-steroid hormone metabolic process; IDA:UniProtKB.::GO:0006707; P:cholesterol catabolic process; IDA:UniProtKB.::GO:0007586; P:digestion; IDA:UniProtKB.
22Q5R5D5    325   AK1A1_PONAB Alcohol dehydrogenase [NADP(+)] O...920.00006     47.8     26     53
GO:0008106; F:alcohol dehydrogenase (NADP+) activity; IEA:EC.
23P14550    325   AK1A1_HUMAN Alcohol dehydrogenase [NADP(+)] O...1190.00006     47.8     23     50
GO:0004032; F:alditol:NADP+ 1-oxidoreductase activity; TAS:ProtInc.::GO:0009055; F:electron carrier activity; TAS:UniProtKB.
GO:0006006; P:glucose metabolic process; TAS:ProtInc.
24Q2UKD0    319   XYL1_ASPOR Probable NAD(P)H-dependent D-xylos...1190.00007     47.4     29     48
GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
GO:0042732; P:D-xylose metabolic process; IEA:UniProtKB-KW.
25B8N195    319   XYL1_ASPFN Probable NAD(P)H-dependent D-xylos...1190.00007     47.4     29     48
GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
GO:0042732; P:D-xylose metabolic process; IEA:UniProtKB-KW.
26O74237    322   XYL1_CANTE NAD(P)H-dependent D-xylose reducta...1260.00009     47     29     48
GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
GO:0042732; P:D-xylose metabolic process; IEA:UniProtKB-KW.
27P50578    325   AK1A1_PIG Alcohol dehydrogenase [NADP(+)] OS=...1190.0001     47     23     49
GO:0008106; F:alcohol dehydrogenase (NADP+) activity; IEA:EC.
28C5FFQ7    327   XYL1_ARTOC Probable NAD(P)H-dependent D-xylos...1240.0001     46.6     31     45
GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
GO:0042732; P:D-xylose metabolic process; IEA:UniProtKB-KW.
29Q9P430    323   XYL1_CANSH NAD(P)H-dependent D-xylose reducta...1260.0001     46.6     30     48
GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
GO:0042732; P:D-xylose metabolic process; IEA:UniProtKB-KW.
30P31210    326   AK1D1_RAT 3-oxo-5-beta-steroid 4-dehydrogenas...970.0002     46.2     31     54
GO:0047568; F:3-oxo-5-beta-steroid 4-dehydrogenase activity; IDA:MGI.::GO:0047787; F:delta4-3-oxosteroid 5beta-reductase activity; IEA:EC.
GO:0030573; P:bile acid catabolic process; IEA:UniProtKB-KW.
31O42888    325   YBN4_SCHPO Uncharacterized oxidoreductase C8E...940.0002     45.8     23     53GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
GO:0004033; F:aldo-keto reductase (NADP) activity; ISS:PomBase.
GO:0019568; P:arabinose catabolic process; ISS:PomBase.::GO:0042843; P:D-xylose catabolic process; ISS:PomBase.
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