| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
511 | Q9QWY8 | 1147 | ASAP1_MOUSE Arf-GAP with SH3 domain, ANK repe... | 77 | 2.4 | 35.4 | 29 | 48 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0008093; F:cytoskeletal adaptor activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0017124; F:SH3 domain binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0060271; P:cilium morphogenesis; ISS:UniProtKB.::GO:0046847; P:filopodium assembly; IEA:InterPro.::GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.::GO:0007165; P:signal transduction; IEA:InterPro. | 512 | Q8CIH5 | 1265 | PLCG2_MOUSE 1-phosphatidylinositol 4,5-bispho... | 55 | 2.4 | 35.4 | 31 | 51 | GO:0005829; C:cytosol; IMP:UniProtKB.::GO:0005886; C:plasma membrane; ISS:UniProtKB. | | | | | | | | | | GO:0004435; F:phosphatidylinositol phospholipase C activity; ISS:UniProtKB.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0032237; P:activation of store-operated calcium channel activity; IMP:MGI.::GO:0050853; P:B cell receptor signaling pathway; IMP:UniProtKB.::GO:0002316; P:follicular B cell differentiation; IMP:MGI.::GO:0032959; P:inositol trisphosphate biosynthetic process; IDA:MGI.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0043069; P:negative regulation of programmed cell death; IMP:MGI.::GO:0006661; P:phosphatidylinositol biosynthetic process; ISS:UniProtKB.::GO:0009395; P:phospholipid catabolic process; IEA:InterPro.::GO:0010468; P:regulation of gene expression; IMP:MGI.::GO:0051209; P:release of sequestered calcium ion into cytosol; IMP:UniProtKB.::GO:0032496; P:response to lipopolysaccharide; IDA:MGI.::GO:0050852; P:T cell receptor signaling pathway; IDA:MGI. | 513 | Q92882 | 214 | OSTF1_HUMAN Osteoclast-stimulating factor 1 O... | 49 | 4 | 33.9 | 37 | 49 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0001503; P:ossification; TAS:ProtInc.::GO:0007165; P:signal transduction; TAS:ProtInc. | 514 | O75044 | 1071 | FNBP2_HUMAN SLIT-ROBO Rho GTPase-activating p... | 264 | 2.6 | 35.4 | 18 | 35 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007411; P:axon guidance; TAS:Reactome.::GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. | 515 | P24135 | 1265 | PLCG2_RAT 1-phosphatidylinositol 4,5-bisphosp... | 55 | 2.6 | 35.4 | 31 | 51 | GO:0005624; C:membrane fraction; IDA:RGD.::GO:0005886; C:plasma membrane; ISS:UniProtKB. | | | | | | | | | | GO:0004435; F:phosphatidylinositol phospholipase C activity; IDA:RGD.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:RGD.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0006661; P:phosphatidylinositol biosynthetic process; ISS:UniProtKB.::GO:0009395; P:phospholipid catabolic process; IEA:InterPro.::GO:0051209; P:release of sequestered calcium ion into cytosol; ISS:UniProtKB.::GO:0033198; P:response to ATP; IDA:RGD.::GO:0032026; P:response to magnesium ion; IDA:RGD. | 516 | Q8MJ49 | 214 | OSTF1_PIG Osteoclast-stimulating factor 1 OS=... | 49 | 4.2 | 33.5 | 37 | 49 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 517 | D3YZU1 | 2167 | SHAN1_MOUSE SH3 and multiple ankyrin repeat d... | 59 | 2.6 | 35.4 | 36 | 54 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0060076; C:excitatory synapse; IDA:BHF-UCL.::GO:0005886; C:plasma membrane; IDA:BHF-UCL.::GO:0014069; C:postsynaptic density; IDA:BHF-UCL.::GO:0045211; C:postsynaptic membrane; IDA:MGI.::GO:0019717; C:synaptosome; IDA:BHF-UCL. | | | | | | | | | | GO:0071532; F:ankyrin repeat binding; ISS:BHF-UCL.::GO:0030160; F:GKAP/Homer scaffold activity; IMP:BHF-UCL.::GO:0042802; F:identical protein binding; ISS:BHF-UCL.::GO:0035255; F:ionotropic glutamate receptor binding; IPI:BHF-UCL.::GO:0097110; F:scaffold protein binding; ISS:BHF-UCL.::GO:0017124; F:SH3 domain binding; ISS:BHF-UCL. | | | | | | | | | | GO:0008306; P:associative learning; IMP:BHF-UCL.::GO:0060997; P:dendritic spine morphogenesis; IMP:BHF-UCL.::GO:0046959; P:habituation; IMP:BHF-UCL.::GO:0007616; P:long-term memory; IMP:BHF-UCL.::GO:0032232; P:negative regulation of actin filament bundle assembly; IDA:MGI.::GO:0050885; P:neuromuscular process controlling balance; IMP:BHF-UCL.::GO:0042048; P:olfactory behavior; IMP:BHF-UCL.::GO:2000463; P:positive regulation of excitatory postsynaptic membrane potential; IMP:BHF-UCL.::GO:0006461; P:protein complex assembly; ISS:BHF-UCL.::GO:0035418; P:protein localization to synapse; IMP:BHF-UCL.::GO:2000311; P:regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity; IMP:BHF-UCL.::GO:0060013; P:righting reflex; IMP:BHF-UCL.::GO:0035176; P:social behavior; IMP:BHF-UCL.::GO:0071625; P:vocalization behavior; IMP:BHF-UCL. | 518 | Q9WV48 | 2167 | SHAN1_RAT SH3 and multiple ankyrin repeat dom... | 59 | 2.6 | 35.4 | 36 | 54 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0060076; C:excitatory synapse; ISS:BHF-UCL.::GO:0005624; C:membrane fraction; IDA:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.::GO:0014069; C:postsynaptic density; ISS:BHF-UCL.::GO:0045211; C:postsynaptic membrane; IDA:RGD. | | | | | | | | | | GO:0071532; F:ankyrin repeat binding; IPI:BHF-UCL.::GO:0030160; F:GKAP/Homer scaffold activity; IDA:BHF-UCL.::GO:0042802; F:identical protein binding; IPI:BHF-UCL.::GO:0035255; F:ionotropic glutamate receptor binding; IPI:RGD.::GO:0008022; F:protein C-terminus binding; IPI:RGD.::GO:0097110; F:scaffold protein binding; IPI:BHF-UCL.::GO:0017124; F:SH3 domain binding; IPI:BHF-UCL.::GO:0031877; F:somatostatin receptor binding; IPI:UniProtKB. | | | | | | | | | | GO:0008306; P:associative learning; ISS:BHF-UCL.::GO:0007016; P:cytoskeletal anchoring at plasma membrane; NAS:UniProtKB.::GO:0060997; P:dendritic spine morphogenesis; ISS:BHF-UCL.::GO:0007616; P:long-term memory; ISS:BHF-UCL.::GO:0050885; P:neuromuscular process controlling balance; ISS:BHF-UCL.::GO:0060999; P:positive regulation of dendritic spine development; IDA:UniProtKB.::GO:2000463; P:positive regulation of excitatory postsynaptic membrane potential; ISS:BHF-UCL.::GO:0006461; P:protein complex assembly; IDA:BHF-UCL.::GO:0035418; P:protein localization to synapse; ISS:BHF-UCL.::GO:2000311; P:regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity; ISS:BHF-UCL.::GO:0060074; P:synapse maturation; IDA:UniProtKB. | 519 | P38339 | 666 | RGD1_YEAST RHO GTPase-activating protein RGD1... | 242 | 2.6 | 35 | 19 | 46 | GO:0030479; C:actin cortical patch; IDA:SGD.::GO:0005933; C:cellular bud; IDA:SGD.::GO:0043332; C:mating projection tip; IDA:SGD. | | | | | | | | | | GO:0080025; F:phosphatidylinositol-3,5-bisphosphate binding; IMP:SGD.::GO:0032266; F:phosphatidylinositol-3-phosphate binding; IMP:SGD.::GO:0005546; F:phosphatidylinositol-4,5-bisphosphate binding; IDA:SGD.::GO:0070273; F:phosphatidylinositol-4-phosphate binding; IMP:SGD.::GO:0010314; F:phosphatidylinositol-5-phosphate binding; IMP:SGD.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0005100; F:Rho GTPase activator activity; IDA:SGD. | | | | | | | | | | GO:0007231; P:osmosensory signaling pathway; IGI:SGD.::GO:0001101; P:response to acid; IMP:SGD. | 520 | Q05080 | 669 | CYK2_YEAST Cytokinesis protein 2 OS=Saccharom... | 229 | 2.6 | 35 | 23 | 42 | GO:0000142; C:cellular bud neck contractile ring; IDA:SGD.::GO:0000144; C:cellular bud neck septin ring; IDA:SGD. | | | | | | | | | | GO:0008092; F:cytoskeletal protein binding; IPI:SGD. | | | | | | | | | | GO:0071937; P:barrier septum assembly involved in cell cycle cytokinesis; IMP:SGD.::GO:0000281; P:cytokinesis after mitosis; IMP:SGD.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006974; P:response to DNA damage stimulus; IMP:SGD. | 521 | O01738 | 486 | DEFI8_CAEEL Differentially expressed in FDCP ... | 92 | 2.7 | 35 | 33 | 41 | | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 522 | Q7Z8J6 | 1282 | MYO1_USTMA Myosin-1 OS=Ustilago maydis (strai... | 51 | 7.5 | 33.9 | 33 | 55 | GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0016459; C:myosin complex; IEA:UniProtKB-KW. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003774; F:motor activity; IEA:InterPro. | | | | | | | | | | | 523 | Q8N3K9 | 4069 | CMYA5_HUMAN Cardiomyopathy-associated protein... | 166 | 3.2 | 35 | 23 | 45 | GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 524 | Q5ZJJ9 | 202 | OSTF1_CHICK Osteoclast-stimulating factor 1 O... | 54 | 3.2 | 33.9 | 30 | 52 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 525 | Q6BVC2 | 304 | SHO1_DEBHA High osmolarity signaling protein ... | 54 | 3.4 | 34.3 | 33 | 54 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006950; P:response to stress; IEA:UniProtKB-KW. | 526 | Q64010 | 304 | CRK_MOUSE Adapter molecule crk OS=Mus musculu... | 85 | 3.4 | 34.3 | 22 | 48 | GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046875; F:ephrin receptor binding; IPI:UniProtKB.::GO:0045309; F:protein phosphorylated amino acid binding; IDA:MGI.::GO:0005070; F:SH3/SH2 adaptor activity; IPI:BHF-UCL. | | | | | | | | | | GO:0048013; P:ephrin receptor signaling pathway; ISS:UniProtKB.::GO:0032956; P:regulation of actin cytoskeleton organization; ISS:UniProtKB.::GO:0032319; P:regulation of Rho GTPase activity; ISS:UniProtKB. | 527 | Q8MJ50 | 214 | OSTF1_BOVIN Osteoclast-stimulating factor 1 O... | 49 | 9.1 | 32.7 | 37 | 49 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 528 | Q9XVN3 | 769 | IASPP_CAEEL Apoptotic enhancer 1 protein OS=C... | 49 | 3.7 | 34.7 | 33 | 55 | GO:0005634; C:nucleus; ISS:WormBase. | | | | | | | | | | GO:0002039; F:p53 binding; IPI:WormBase. | | | | | | | | | | GO:0006915; P:apoptotic process; IMP:WormBase.::GO:0043066; P:negative regulation of apoptotic process; IMP:WormBase. | 529 | Q54GD0 | 920 | MGP1_DICDI Mental retardation GTPase activati... | 243 | 3.8 | 34.7 | 20 | 40 | GO:0000331; C:contractile vacuole; IDA:dictyBase.::GO:0005829; C:cytosol; IDA:dictyBase. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0033298; P:contractile vacuole organization; IMP:dictyBase.::GO:0006887; P:exocytosis; IGI:dictyBase.::GO:0051490; P:negative regulation of filopodium assembly; IMP:dictyBase.::GO:0042331; P:phototaxis; IGI:dictyBase.::GO:0051270; P:regulation of cellular component movement; IMP:dictyBase.::GO:0007165; P:signal transduction; IEA:InterPro. | 530 | Q96HL8 | 342 | SH3Y1_HUMAN SH3 domain-containing YSC84-like ... | 52 | 3.8 | 34.3 | 33 | 54 | | | | | | | | | | | | | | | | | | | | | | 531 | Q91ZR2 | 614 | SNX18_MOUSE Sorting nexin-18 OS=Mus musculus ... | 54 | 3.9 | 34.7 | 31 | 54 | GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0031234; C:extrinsic to internal side of plasma membrane; ISS:UniProtKB. | | | | | | | | | | GO:0035091; F:phosphatidylinositol binding; IEA:InterPro. | | | | | | | | | | GO:0007154; P:cell communication; IEA:InterPro.::GO:0006897; P:endocytosis; ISS:UniProtKB.::GO:0043547; P:positive regulation of GTPase activity; ISS:UniProtKB.::GO:0015031; P:protein transport; IEA:UniProtKB-KW. | 532 | Q751J2 | 330 | SHO1_ASHGO High osmolarity signaling protein ... | 53 | 4.1 | 34.3 | 38 | 58 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006950; P:response to stress; IEA:UniProtKB-KW. | 533 | Q3SZ01 | 341 | SH3Y1_BOVIN SH3 domain-containing YSC84-like ... | 52 | 4.1 | 34.3 | 33 | 54 | | | | | | | | | | | | | | | | | | | | | | 534 | Q8TEJ3 | 882 | SH3R3_HUMAN SH3 domain-containing RING finger... | 56 | 8.4 | 33.5 | 36 | 52 | | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 535 | P00528 | 552 | SRC64_DROME Tyrosine-protein kinase Src64B OS... | 66 | 4.2 | 34.3 | 32 | 52 | GO:0045172; C:germline ring canal; IDA:FlyBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0007349; P:cellularization; IMP:FlyBase.::GO:0007391; P:dorsal closure; TAS:FlyBase.::GO:0008302; P:female germline ring canal formation, actin assembly; IMP:FlyBase.::GO:0008335; P:female germline ring canal stabilization; IMP:FlyBase.::GO:0030708; P:germarium-derived female germ-line cyst encapsulation; IMP:FlyBase.::GO:0007254; P:JNK cascade; TAS:FlyBase.::GO:0030717; P:karyosome formation; IMP:FlyBase.::GO:0016319; P:mushroom body development; IMP:FlyBase.::GO:0008355; P:olfactory learning; IMP:FlyBase.::GO:0030723; P:ovarian fusome organization; IMP:FlyBase.::GO:0030046; P:parallel actin filament bundle assembly; IMP:FlyBase.::GO:0018108; P:peptidyl-tyrosine phosphorylation; IGI:FlyBase.::GO:0008064; P:regulation of actin polymerization or depolymerization; IMP:FlyBase.::GO:0007435; P:salivary gland morphogenesis; IMP:FlyBase. | 536 | P55345 | 433 | ANM2_HUMAN Protein arginine N-methyltransfera... | 50 | 4.3 | 34.3 | 30 | 56 | GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB. | | | | | | | | | | GO:0050681; F:androgen receptor binding; IPI:UniProtKB.::GO:0030331; F:estrogen receptor binding; IDA:UniProtKB.::GO:0008469; F:histone-arginine N-methyltransferase activity; ISS:UniProtKB.::GO:0008168; F:methyltransferase activity; IEA:InterPro.::GO:0042975; F:peroxisome proliferator activated receptor binding; IPI:UniProtKB.::GO:0033142; F:progesterone receptor binding; IPI:UniProtKB.::GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.::GO:0042974; F:retinoic acid receptor binding; IPI:UniProtKB.::GO:0004871; F:signal transducer activity; TAS:ProtInc.::GO:0046966; F:thyroid hormone receptor binding; IPI:UniProtKB.::GO:0003713; F:transcription coactivator activity; IDA:UniProtKB. | | | | | | | | | | GO:0048588; P:developmental cell growth; ISS:UniProtKB.::GO:0006917; P:induction of apoptosis; IDA:UniProtKB.::GO:2000134; P:negative regulation of G1/S transition of mitotic cell cycle; ISS:UniProtKB.::GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; IDA:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0060765; P:regulation of androgen receptor signaling pathway; IDA:UniProtKB. | 537 | Q5RAQ2 | 342 | SH3Y1_PONAB SH3 domain-containing YSC84-like ... | 52 | 4.4 | 33.9 | 33 | 54 | | | | | | | | | | | | | | | | | | | | | | 538 | Q80U22 | 1514 | RUSC2_MOUSE Iporin OS=Mus musculus (Mouse). G... | 58 | 4.4 | 34.7 | 33 | 55 | GO:0005829; C:cytosol; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 539 | O70145 | 525 | NCF2_MOUSE Neutrophil cytosol factor 2 OS=Mus... | 81 | 4.6 | 34.3 | 25 | 47 | GO:0001669; C:acrosomal vesicle; IDA:MGI. | | | | | | | | | | GO:0048365; F:Rac GTPase binding; IPI:MGI. | | | | | | | | | | GO:0042554; P:superoxide anion generation; IDA:MGI. | 540 | O32041 | 518 | YRVJ_BACSU Putative N-acetylmuramoyl-L-alanin... | 138 | 4.7 | 34.3 | 24 | 41 | GO:0005618; C:cell wall; IEA:UniProtKB-SubCell.::GO:0005576; C:extracellular region; IEA:UniProtKB-KW. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008745; F:N-acetylmuramoyl-L-alanine amidase activity; IEA:EC. | | | | | | | | | | GO:0007047; P:cellular cell wall organization; IEA:UniProtKB-KW.::GO:0009253; P:peptidoglycan catabolic process; IEA:InterPro. | 541 | P70297 | 548 | STAM1_MOUSE Signal transducing adapter molecu... | 76 | 4.8 | 34.3 | 24 | 51 | GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005515; F:protein binding; IPI:MGI. | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. |
