| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
421 | Q9CX99 | 217 | GRAP_MOUSE GRB2-related adapter protein OS=Mu... | 48 | 0.5 | 36.6 | 27 | 54 | | | | | | | | | | | | | | | | | | | | | | 422 | Q6GM14 | 376 | DBNLB_XENLA Drebrin-like protein B OS=Xenopus... | 50 | 8.1 | 33.1 | 36 | 44 | GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW. | | | | | | | | | | | 423 | B3LXF2 | 1916 | DGKH_DROAN Diacylglycerol kinase eta OS=Droso... | 53 | 0.37 | 38.1 | 26 | 51 | GO:0005768; C:endosome; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004143; F:diacylglycerol kinase activity; ISS:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0007205; P:activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway; ISS:UniProtKB.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0051259; P:protein oligomerization; ISS:UniProtKB. | 424 | P35991 | 659 | BTK_MOUSE Tyrosine-protein kinase BTK OS=Mus ... | 68 | 0.38 | 37.7 | 29 | 51 | GO:0031410; C:cytoplasmic vesicle; IDA:MGI.::GO:0005634; C:nucleus; IDA:MGI.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0048469; P:cell maturation; IMP:MGI.::GO:0007249; P:I-kappaB kinase/NF-kappaB cascade; IMP:MGI.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW.::GO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:MGI.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 425 | Q99JB8 | 424 | PACN3_MOUSE Protein kinase C and casein kinas... | 53 | 8.3 | 33.1 | 32 | 51 | GO:0005737; C:cytoplasm; IDA:MGI.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008092; F:cytoskeletal protein binding; IDA:MGI. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0045806; P:negative regulation of endocytosis; IDA:MGI. | 426 | P49710 | 486 | HCLS1_MOUSE Hematopoietic lineage cell-specif... | 48 | 0.39 | 37.7 | 42 | 52 | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:UniProtKB. | | | | | | | | | | GO:0032403; F:protein complex binding; IPI:MGI.::GO:0017124; F:SH3 domain binding; IDA:MGI. | | | | | | | | | | GO:0030218; P:erythrocyte differentiation; IMP:UniProtKB.::GO:0008284; P:positive regulation of cell proliferation; IMP:UniProtKB.::GO:0042531; P:positive regulation of tyrosine phosphorylation of STAT protein; IMP:UniProtKB.::GO:0009725; P:response to hormone stimulus; IDA:UniProtKB. | 427 | Q62420 | 352 | SH3G2_MOUSE Endophilin-A1 OS=Mus musculus (Mo... | 50 | 0.4 | 37.4 | 38 | 48 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008289; F:lipid binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0002090; P:regulation of receptor internalization; IDA:MGI.::GO:0048488; P:synaptic vesicle endocytosis; IGI:MGI. | 428 | Q63356 | 1107 | MYO1E_RAT Unconventional myosin-Ie OS=Rattus ... | 138 | 0.42 | 37.7 | 28 | 38 | GO:0005912; C:adherens junction; ISS:UniProtKB.::GO:0005911; C:cell-cell junction; ISS:UniProtKB.::GO:0030136; C:clathrin-coated vesicle; IEA:UniProtKB-SubCell.::GO:0016459; C:myosin complex; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051015; F:actin filament binding; ISS:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042623; F:ATPase activity, coupled; ISS:UniProtKB.::GO:0005516; F:calmodulin binding; ISS:UniProtKB.::GO:0003774; F:motor activity; IEA:InterPro.::GO:0035091; F:phosphatidylinositol binding; ISS:UniProtKB.::GO:0032403; F:protein complex binding; IDA:RGD. | | | | | | | | | | GO:0006897; P:endocytosis; ISS:UniProtKB.::GO:0032836; P:glomerular basement membrane development; ISS:UniProtKB.::GO:0003094; P:glomerular filtration; ISS:UniProtKB.::GO:0072015; P:glomerular visceral epithelial cell development; ISS:UniProtKB. | 429 | O35179 | 352 | SH3G2_RAT Endophilin-A1 OS=Rattus norvegicus ... | 50 | 0.42 | 37.4 | 38 | 48 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; TAS:Reactome. | | | | | | | | | | GO:0008289; F:lipid binding; IEA:UniProtKB-KW. | | | | | | | | | | | 430 | Q9UNA1 | 814 | RHG26_HUMAN Rho GTPase-activating protein 26 ... | 62 | 6.3 | 33.9 | 34 | 47 | GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008093; F:cytoskeletal adaptor activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005100; F:Rho GTPase activator activity; NAS:UniProtKB.::GO:0017124; F:SH3 domain binding; IEA:InterPro. | | | | | | | | | | GO:0030036; P:actin cytoskeleton organization; NAS:UniProtKB.::GO:0046847; P:filopodium assembly; IEA:InterPro.::GO:0007399; P:nervous system development; NAS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. | 431 | A8WVU9 | 1194 | ROCK_CAEBR Rho-associated protein kinase let-... | 45 | 0.43 | 37.7 | 31 | 53 | GO:0032154; C:cleavage furrow; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0048477; P:oogenesis; IEA:UniProtKB-KW. | 432 | Q2HDI2 | 1214 | MYO1_CHAGB Myosin-1 OS=6347 / NRRL 1970) (Soi... | 51 | 0.44 | 37.7 | 33 | 59 | GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0016459; C:myosin complex; IEA:UniProtKB-KW. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003774; F:motor activity; IEA:InterPro. | | | | | | | | | | | 433 | Q99962 | 352 | SH3G2_HUMAN Endophilin-A1 OS=Homo sapiens (Hu... | 50 | 0.44 | 37.4 | 38 | 48 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0000139; C:Golgi membrane; TAS:Reactome.::GO:0005886; C:plasma membrane; TAS:Reactome. | | | | | | | | | | GO:0042802; F:identical protein binding; IPI:IntAct.::GO:0008289; F:lipid binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007411; P:axon guidance; TAS:Reactome.::GO:0016044; P:cellular membrane organization; TAS:Reactome.::GO:0007417; P:central nervous system development; TAS:ProtInc.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0042059; P:negative regulation of epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0006892; P:post-Golgi vesicle-mediated transport; TAS:Reactome. | 434 | Q06187 | 659 | BTK_HUMAN Tyrosine-protein kinase BTK OS=Homo... | 58 | 0.44 | 37.7 | 29 | 55 | GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0045121; C:membrane raft; IDA:HGNC.::GO:0005634; C:nucleus; TAS:UniProtKB.::GO:0005886; C:plasma membrane; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; TAS:HGNC.::GO:0042802; F:identical protein binding; IPI:IntAct.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; TAS:UniProtKB.::GO:0005547; F:phosphatidylinositol-3,4,5-trisphosphate binding; IDA:UniProtKB. | | | | | | | | | | GO:0002250; P:adaptive immune response; TAS:UniProtKB.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0042113; P:B cell activation; TAS:UniProtKB.::GO:0050853; P:B cell receptor signaling pathway; TAS:UniProtKB.::GO:0019722; P:calcium-mediated signaling; TAS:HGNC.::GO:0008624; P:induction of apoptosis by extracellular signals; TAS:ProtInc.::GO:0045087; P:innate immune response; TAS:UniProtKB.::GO:0007498; P:mesoderm development; TAS:ProtInc.::GO:0045579; P:positive regulation of B cell differentiation; TAS:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; TAS:UniProtKB.::GO:0002902; P:regulation of B cell apoptotic process; TAS:UniProtKB.::GO:0002721; P:regulation of B cell cytokine production; TAS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 435 | O74653 | 871 | POB1_SCHPO Protein pob1 OS=Schizosaccharomyce... | 57 | 0.44 | 37.7 | 32 | 60 | GO:0051285; C:cell cortex of cell tip; IDA:PomBase.::GO:0032153; C:cell division site; IDA:PomBase.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0000920; P:cytokinetic cell separation; IMP:PomBase.::GO:0008360; P:regulation of cell shape; IMP:PomBase. | 436 | O43586 | 416 | PPIP1_HUMAN Proline-serine-threonine phosphat... | 83 | 0.45 | 37.4 | 29 | 45 | GO:0032154; C:cleavage furrow; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016491; F:oxidoreductase activity; IEA:InterPro. | | | | | | | | | | GO:0007155; P:cell adhesion; TAS:ProtInc.::GO:0045087; P:innate immune response; TAS:Reactome.::GO:0035872; P:nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway; TAS:Reactome. | 437 | B3NYS4 | 1918 | DGKH_DROER Diacylglycerol kinase eta OS=Droso... | 53 | 0.45 | 37.7 | 26 | 51 | GO:0005768; C:endosome; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004143; F:diacylglycerol kinase activity; ISS:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0007205; P:activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway; ISS:UniProtKB.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0051259; P:protein oligomerization; ISS:UniProtKB. | 438 | B4R0A5 | 1905 | DGKH_DROSI Diacylglycerol kinase eta OS=Droso... | 53 | 0.46 | 37.7 | 26 | 51 | GO:0005768; C:endosome; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004143; F:diacylglycerol kinase activity; ISS:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0007205; P:activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway; ISS:UniProtKB.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0051259; P:protein oligomerization; ISS:UniProtKB. | 439 | B4I4Y1 | 1914 | DGKH_DROSE Diacylglycerol kinase eta OS=Droso... | 53 | 0.47 | 37.7 | 26 | 51 | GO:0005768; C:endosome; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004143; F:diacylglycerol kinase activity; ISS:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0007205; P:activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway; ISS:UniProtKB.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0051259; P:protein oligomerization; ISS:UniProtKB. | 440 | B4PRE2 | 1917 | DGKH_DROYA Diacylglycerol kinase eta OS=Droso... | 53 | 0.47 | 37.7 | 26 | 51 | GO:0005768; C:endosome; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004143; F:diacylglycerol kinase activity; ISS:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0007205; P:activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway; ISS:UniProtKB.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0051259; P:protein oligomerization; ISS:UniProtKB. | 441 | Q9VTT9 | 492 | DEFI8_DROME Differentially expressed in FDCP ... | 62 | 0.49 | 37.4 | 32 | 40 | | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 442 | Q8AXU9 | 353 | SH3G3_CHICK Endophilin-A3 OS=Gallus gallus (C... | 50 | 0.51 | 37 | 38 | 48 | GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008289; F:lipid binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW. | 443 | O97902 | 1129 | ASAP1_BOVIN Arf-GAP with SH3 domain, ANK repe... | 104 | 0.51 | 37.4 | 29 | 45 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0008093; F:cytoskeletal adaptor activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0017124; F:SH3 domain binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0060271; P:cilium morphogenesis; ISS:UniProtKB.::GO:0046847; P:filopodium assembly; IEA:InterPro.::GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.::GO:0007165; P:signal transduction; IEA:InterPro. | 444 | P47941 | 303 | CRKL_MOUSE Crk-like protein OS=Mus musculus (... | 57 | 3 | 34.7 | 26 | 46 | | | | | | | | | | | GO:0005515; F:protein binding; IPI:MGI. | | | | | | | | | | GO:0009952; P:anterior/posterior pattern specification; IGI:MGI.::GO:0001568; P:blood vessel development; IGI:MGI.::GO:0007507; P:heart development; IGI:MGI.::GO:0009887; P:organ morphogenesis; IMP:MGI.::GO:0060017; P:parathyroid gland development; IGI:MGI.::GO:0048538; P:thymus development; IGI:MGI. | 445 | A8JQ65 | 1895 | DGKH_DROME Diacylglycerol kinase eta OS=Droso... | 53 | 0.54 | 37.4 | 26 | 51 | GO:0005768; C:endosome; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004143; F:diacylglycerol kinase activity; ISS:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0007205; P:activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway; ISS:UniProtKB.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0051259; P:protein oligomerization; ISS:UniProtKB. | 446 | A8MVU1 | 366 | NCF1C_HUMAN Putative neutrophil cytosol facto... | 144 | 0.55 | 37 | 24 | 40 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.::GO:0016175; F:superoxide-generating NADPH oxidase activity; IEA:InterPro. | | | | | | | | | | GO:0007154; P:cell communication; IEA:InterPro. | 447 | A6NI72 | 391 | NCF1B_HUMAN Putative neutrophil cytosol facto... | 144 | 0.56 | 37 | 24 | 40 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0035091; F:phosphatidylinositol binding; IEA:InterPro. | | | | | | | | | | GO:0007154; P:cell communication; IEA:InterPro. | 448 | P14598 | 390 | NCF1_HUMAN Neutrophil cytosol factor 1 OS=Hom... | 144 | 0.58 | 37 | 24 | 40 | GO:0005829; C:cytosol; TAS:ProtInc.::GO:0043020; C:NADPH oxidase complex; TAS:BHF-UCL.::GO:0032010; C:phagolysosome; TAS:Reactome.::GO:0005625; C:soluble fraction; TAS:ProtInc. | | | | | | | | | | GO:0009055; F:electron carrier activity; TAS:UniProtKB.::GO:0005525; F:GTP binding; TAS:ProtInc.::GO:0003924; F:GTPase activity; TAS:ProtInc.::GO:0035091; F:phosphatidylinositol binding; IDA:UniProtKB.::GO:0017124; F:SH3 domain binding; IPI:BHF-UCL. | | | | | | | | | | GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.::GO:0007154; P:cell communication; IEA:InterPro.::GO:0006968; P:cellular defense response; TAS:ProtInc.::GO:0045087; P:innate immune response; TAS:BHF-UCL.::GO:0006612; P:protein targeting to membrane; IDA:UniProtKB.::GO:0042554; P:superoxide anion generation; TAS:BHF-UCL. | 449 | Q4JIM5 | 1182 | ABL2_MOUSE Abelson tyrosine-protein kinase 2 ... | 113 | 1.2 | 36.2 | 23 | 47 | GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0030145; F:manganese ion binding; IDA:UniProtKB.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | GO:0030036; P:actin cytoskeleton organization; IDA:UniProtKB.::GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:UniProtKB. | 450 | Q9P2A4 | 366 | ABI3_HUMAN ABI gene family member 3 OS=Homo s... | 52 | 1 | 36.2 | 35 | 50 | GO:0005737; C:cytoplasm; NAS:UniProtKB.::GO:0030027; C:lamellipodium; IDA:MGI. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0006928; P:cellular component movement; NAS:UniProtKB.::GO:0030334; P:regulation of cell migration; IDA:MGI. | 451 | O60861 | 476 | GAS7_HUMAN Growth arrest-specific protein 7 O... | 264 | 0.65 | 37 | 19 | 39 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc. | | | | | | | | | | GO:0007050; P:cell cycle arrest; TAS:ProtInc. |
