Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Coccidiodis immitis RS
Locus:
CIMG_00161
Length:
1071
Number of sequences:
9910
Description:
HLH transcription factor
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
91P21438    437   MYC_FLVTT Viral myc transforming protein OS=F...1020.12     39.7     27     41GO:0042025; C:host cell nucleus; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:InterPro.
GO:0070888; F:E-box binding; ISS:UniProtKB.::GO:0032403; F:protein complex binding; ISS:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; ISS:UniProtKB.
GO:0060070; P:canonical Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0006879; P:cellular iron ion homeostasis; ISS:UniProtKB.::GO:0006338; P:chromatin remodeling; ISS:UniProtKB.::GO:0000165; P:MAPK cascade; ISS:UniProtKB.::GO:0051782; P:negative regulation of cell division; ISS:UniProtKB.::GO:0045656; P:negative regulation of monocyte differentiation; ISS:UniProtKB.::GO:0043280; P:positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; ISS:UniProtKB.::GO:2000573; P:positive regulation of DNA biosynthetic process; ISS:UniProtKB.::GO:0050679; P:positive regulation of epithelial cell proliferation; ISS:UniProtKB.::GO:0048146; P:positive regulation of fibroblast proliferation; ISS:UniProtKB.::GO:2001022; P:positive regulation of response to DNA damage stimulus; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0032204; P:regulation of telomere maintenance; ISS:UniProtKB.::GO:0006974; P:response to DNA damage stimulus; ISS:UniProtKB.::GO:0010332; P:response to gamma radiation; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
92P19484    476   TFEB_HUMAN Transcription factor EB OS=Homo sa...1070.13     39.7     28     45GO:0005737; C:cytoplasm; IDA:UniProtKB.
GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.::GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB.
GO:0001892; P:embryonic placenta development; ISS:UniProtKB.::GO:0006959; P:humoral immune response; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
93Q15853    346   USF2_HUMAN Upstream stimulatory factor 2 OS=H...1060.13     39.7     28     47GO:0005634; C:nucleus; IDA:BHF-UCL.
GO:0043425; F:bHLH transcription factor binding; IPI:BHF-UCL.::GO:0046982; F:protein heterodimerization activity; IPI:BHF-UCL.::GO:0042803; F:protein homodimerization activity; IPI:BHF-UCL.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IMP:BHF-UCL.::GO:0043565; F:sequence-specific DNA binding; IDA:BHF-UCL.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
GO:0019086; P:late viral mRNA transcription; IC:BHF-UCL.::GO:0055088; P:lipid homeostasis; ISS:BHF-UCL.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.::GO:0000432; P:positive regulation of transcription from RNA polymerase II promoter by glucose; IMP:BHF-UCL.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
94Q9FHA2    210   ALC_ARATH Transcription factor ALC OS=Arabido...780.15     38.5     28     50GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
GO:0010047; P:fruit dehiscence; IMP:TAIR.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
95Q9FUA4    373   SPT_ARATH Transcription factor SPATULA OS=Ara...820.16     39.3     29     49GO:0005634; C:nucleus; IDA:TAIR.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0048440; P:carpel development; IMP:TAIR.::GO:0007623; P:circadian rhythm; IEP:TAIR.::GO:0010154; P:fruit development; IMP:TAIR.::GO:0010187; P:negative regulation of seed germination; IMP:TAIR.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0009409; P:response to cold; IMP:TAIR.::GO:0010114; P:response to red light; IMP:TAIR.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
96Q8S3F1    320   BH020_ARATH Transcription factor NAI1 OS=Arab...1420.18     38.9     24     40GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
GO:0006355; P:regulation of transcription, DNA-dependent; TAS:TAIR.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
97Q63665    346   USF2_RAT Upstream stimulatory factor 2 OS=Rat...1050.27     38.5     28     46GO:0005634; C:nucleus; IDA:RGD.
GO:0003690; F:double-stranded DNA binding; IDA:RGD.::GO:0046982; F:protein heterodimerization activity; IMP:RGD.::GO:0042803; F:protein homodimerization activity; IMP:RGD.::GO:0000978; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding; IDA:RGD.
98Q64705    346   USF2_MOUSE Upstream stimulatory factor 2 OS=M...1050.27     38.5     28     46GO:0005634; C:nucleus; IDA:MGI.
GO:0007595; P:lactation; IMP:MGI.::GO:0055088; P:lipid homeostasis; IMP:BHF-UCL.::GO:0000432; P:positive regulation of transcription from RNA polymerase II promoter by glucose; IMP:BHF-UCL.
99Q9WV93    299   HEY1_MOUSE Hairy/enhancer-of-split related wi...880.43     37.7     31     44GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005654; C:nucleoplasm; TAS:Reactome.
GO:0035939; F:microsatellite binding; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0000988; F:protein binding transcription factor activity; IDA:UniProtKB.::GO:0001078; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription; IDA:UniProtKB.::GO:0000983; F:RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.
GO:0072049; P:comma-shaped body morphogenesis; IEP:UniProtKB.::GO:0045665; P:negative regulation of neuron differentiation; IMP:UniProtKB.::GO:0007219; P:Notch signaling pathway; IDA:UniProtKB.::GO:0045747; P:positive regulation of Notch signaling pathway; TAS:BHF-UCL.::GO:0072087; P:renal vesicle development; IEP:UniProtKB.::GO:0072050; P:S-shaped body morphogenesis; IEP:UniProtKB.::GO:0060675; P:ureteric bud morphogenesis; IEP:UniProtKB.
100P97831    160   TWST2_RAT Twist-related protein 2 OS=Rattus n...670.52     36.6     39     52GO:0005737; C:cytoplasm; ISS:UniProtKB.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
GO:0043066; P:negative regulation of apoptotic process; IDA:RGD.::GO:0045668; P:negative regulation of osteoblast differentiation; ISS:UniProtKB.
101Q8WVJ9    160   TWST2_HUMAN Twist-related protein 2 OS=Homo s...670.52     36.6     39     52GO:0005737; C:cytoplasm; IDA:UniProtKB.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
GO:0045668; P:negative regulation of osteoblast differentiation; IDA:UniProtKB.
102Q9D030    160   TWST2_MOUSE Twist-related protein 2 OS=Mus mu...670.55     36.2     39     52GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005667; C:transcription factor complex; IPI:MGI.
GO:0003682; F:chromatin binding; IDA:MGI.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0019904; F:protein domain specific binding; IPI:MGI.::GO:0001076; F:RNA polymerase II transcription factor binding transcription factor activity; IDA:MGI.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:MGI.
GO:0061303; P:cornea development in camera-type eye; IMP:MGI.::GO:0048701; P:embryonic cranial skeleton morphogenesis; IGI:MGI.::GO:0060325; P:face morphogenesis; IMP:MGI.::GO:0008285; P:negative regulation of cell proliferation; IMP:MGI.::GO:0043392; P:negative regulation of DNA binding; IDA:MGI.::GO:0045638; P:negative regulation of myeloid cell differentiation; IMP:MGI.::GO:0045668; P:negative regulation of osteoblast differentiation; ISS:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:MGI.::GO:0032720; P:negative regulation of tumor necrosis factor production; IMP:MGI.::GO:0001649; P:osteoblast differentiation; IMP:MGI.::GO:0010838; P:positive regulation of keratinocyte proliferation; IMP:MGI.
103O80536    524   PIF3_ARATH Transcription factor PIF3 OS=Arabi...740.56     37.7     30     49GO:0005634; C:nucleus; IDA:TAIR.
GO:0003677; F:DNA binding; IDA:TAIR.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0009704; P:de-etiolation; IMP:TAIR.::GO:0009740; P:gibberellic acid mediated signaling pathway; IMP:TAIR.::GO:0031539; P:positive regulation of anthocyanin metabolic process; IMP:TAIR.::GO:0009585; P:red, far-red light phototransduction; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; TAS:TAIR.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
104Q6XBT4    310   USF1_BOVIN Upstream stimulatory factor 1 OS=B...850.58     37.4     29     45
105O02818    310   USF1_RABIT Upstream stimulatory factor 1 OS=O...850.6     37.4     29     45
106P22415    310   USF1_HUMAN Upstream stimulatory factor 1 OS=H...850.64     37.4     29     45GO:0005667; C:transcription factor complex; IDA:BHF-UCL.
GO:0043425; F:bHLH transcription factor binding; IPI:BHF-UCL.::GO:0042826; F:histone deacetylase binding; IPI:BHF-UCL.::GO:0046982; F:protein heterodimerization activity; IPI:BHF-UCL.::GO:0042803; F:protein homodimerization activity; IPI:BHF-UCL.::GO:0019901; F:protein kinase binding; IPI:BHF-UCL.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IDA:BHF-UCL.::GO:0043565; F:sequence-specific DNA binding; IDA:BHF-UCL.
GO:0032869; P:cellular response to insulin stimulus; IDA:BHF-UCL.::GO:0042593; P:glucose homeostasis; TAS:BHF-UCL.::GO:0019086; P:late viral mRNA transcription; IDA:BHF-UCL.::GO:0055088; P:lipid homeostasis; ISS:BHF-UCL.::GO:0051918; P:negative regulation of fibrinolysis; IC:BHF-UCL.::GO:0000432; P:positive regulation of transcription from RNA polymerase II promoter by glucose; IMP:BHF-UCL.::GO:0001666; P:response to hypoxia; IMP:BHF-UCL.::GO:0009411; P:response to UV; ISS:BHF-UCL.
107O35185    411   BHE40_MOUSE Class E basic helix-loop-helix pr...1130.64     37.4     27     43GO:0005654; C:nucleoplasm; TAS:Reactome.
GO:0070888; F:E-box binding; IDA:BHF-UCL.::GO:0043426; F:MRF binding; IDA:BHF-UCL.::GO:0046982; F:protein heterodimerization activity; IDA:BHF-UCL.::GO:0001102; F:RNA polymerase II activating transcription factor binding; IDA:BHF-UCL.::GO:0001078; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription; IDA:BHF-UCL.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IDA:BHF-UCL.
GO:0032922; P:circadian regulation of gene expression; IMP:BHF-UCL.::GO:0043153; P:entrainment of circadian clock by photoperiod; IMP:BHF-UCL.
108Q1LWL8    404   MCL1B_DANRE Protein L-Myc-1b OS=Danio rerio (...850.67     37.4     26     46GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
109P32607    177   RTG1_YEAST Retrograde regulation protein 1 OS...1020.82     36.2     25     44GO:0005737; C:cytoplasm; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0000981; F:sequence-specific DNA binding RNA polymerase II transcription factor activity; IDA:SGD.
GO:0071400; P:cellular response to oleic acid; IMP:SGD.::GO:0031930; P:mitochondria-nucleus signaling pathway; IDA:SGD.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:SGD.
110Q61069    310   USF1_MOUSE Upstream stimulatory factor 1 OS=M...850.93     36.6     29     45GO:0005667; C:transcription factor complex; IC:MGI.
GO:0003677; F:DNA binding; IDA:MGI.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:MGI.
GO:0055088; P:lipid homeostasis; IMP:BHF-UCL.::GO:0000432; P:positive regulation of transcription from RNA polymerase II promoter by glucose; IMP:BHF-UCL.::GO:0009411; P:response to UV; IMP:BHF-UCL.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
111Q07957    307   USF1_XENBO Upstream stimulatory factor 1 OS=X...1011     36.6     32     45GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
112Q2HIV9    248   BH035_ARATH Transcription factor bHLH35 OS=Ar...1211.1     36.2     28     44GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
GO:0006355; P:regulation of transcription, DNA-dependent; TAS:TAIR.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
113P23999    429   MYCS_RAT Protein S-Myc OS=Rattus norvegicus (...1021.2     36.6     27     40GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
114P91664    161   MAX_DROME Protein max OS=Drosophila melanogas...1401.3     35.4     25     42GO:0005634; C:nucleus; IC:UniProtKB.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0046982; F:protein heterodimerization activity; IPI:FlyBase.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.
GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:FlyBase.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
115O14503    412   BHE40_HUMAN Class E basic helix-loop-helix pr...1131.3     36.6     26     43GO:0005794; C:Golgi apparatus; IDA:HPA.::GO:0005730; C:nucleolus; IDA:HPA.
GO:0070888; F:E-box binding; IDA:BHF-UCL.::GO:0043426; F:MRF binding; ISS:BHF-UCL.::GO:0019904; F:protein domain specific binding; IPI:BHF-UCL.::GO:0046982; F:protein heterodimerization activity; IPI:BHF-UCL.::GO:0042803; F:protein homodimerization activity; IDA:BHF-UCL.::GO:0001102; F:RNA polymerase II activating transcription factor binding; ISS:BHF-UCL.::GO:0001078; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription; IDA:BHF-UCL.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; ISS:BHF-UCL.::GO:0001191; F:RNA polymerase II transcription factor binding transcription factor activity involved in negative regulation of transcription; IDA:BHF-UCL.
GO:0032922; P:circadian regulation of gene expression; IDA:BHF-UCL.::GO:0043153; P:entrainment of circadian clock by photoperiod; ISS:BHF-UCL.::GO:0043433; P:negative regulation of sequence-specific DNA binding transcription factor activity; IDA:BHF-UCL.
116P26014    427   MYCN_SERCA N-myc proto-oncogene protein OS=Se...981.4     36.6     27     41GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
117Q5RAI7    412   BHE40_PONAB Class E basic helix-loop-helix pr...1131.4     36.2     26     43GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
118B3F209    412   BHE40_SHEEP Class E basic helix-loop-helix pr...1131.4     36.2     26     43GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
119Q5EA15    412   BHE40_BOVIN Class E basic helix-loop-helix pr...1131.5     36.2     26     43
120Q9QUS4    339   HEY2_MOUSE Hairy/enhancer-of-split related wi...1021.5     36.2     26     43GO:0005737; C:cytoplasm; IDA:UniProtKB.
GO:0035939; F:microsatellite binding; IDA:UniProtKB.::GO:0000988; F:protein binding transcription factor activity; IDA:UniProtKB.::GO:0000983; F:RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.
GO:0009948; P:anterior/posterior axis specification; IGI:MGI.::GO:0060840; P:artery development; IGI:MGI.::GO:0003171; P:atrioventricular valve development; IMP:MGI.::GO:0014898; P:cardiac muscle hypertrophy in response to stress; IDA:MGI.::GO:0060948; P:cardiac vascular smooth muscle cell development; IMP:MGI.::GO:0045165; P:cell fate commitment; IMP:MGI.::GO:0090102; P:cochlea development; IMP:MGI.::GO:0060977; P:coronary vasculature morphogenesis; IMP:MGI.::GO:0003199; P:endocardial cushion to mesenchymal transition involved in heart valve formation; IGI:MGI.::GO:0010667; P:negative regulation of cardiac muscle cell apoptotic process; IMP:MGI.::GO:0045746; P:negative regulation of Notch signaling pathway; IMP:UniProtKB.::GO:2000820; P:negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation; IDA:BHF-UCL.::GO:2000678; P:negative regulation of transcription regulatory region DNA binding; IDA:BHF-UCL.::GO:0007219; P:Notch signaling pathway; IDA:UniProtKB.::GO:0060045; P:positive regulation of cardiac muscle cell proliferation; IMP:MGI.::GO:0010460; P:positive regulation of heart rate; IMP:MGI.::GO:0045747; P:positive regulation of Notch signaling pathway; TAS:BHF-UCL.::GO:0065004; P:protein-DNA complex assembly; IDA:MGI.::GO:0045607; P:regulation of auditory receptor cell differentiation; IGI:MGI.::GO:0003195; P:tricuspid valve formation; IMP:MGI.::GO:0001570; P:vasculogenesis; IGI:MGI.::GO:0055015; P:ventricular cardiac muscle cell development; IMP:BHF-UCL.::GO:0003222; P:ventricular trabecula myocardium morphogenesis; IGI:MGI.
121Q9NQ87    328   HEYL_HUMAN Hairy/enhancer-of-split related wi...1012     35.8     28     46GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0050683; F:AF-1 domain binding; IPI:UniProtKB.::GO:0035939; F:microsatellite binding; IDA:UniProtKB.::GO:0046982; F:protein heterodimerization activity; IDA:UniProtKB.::GO:0000983; F:RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity; ISS:UniProtKB.::GO:0008134; F:transcription factor binding; NAS:UniProtKB.
GO:0003198; P:epithelial to mesenchymal transition involved in endocardial cushion formation; ISS:UniProtKB.::GO:2000824; P:negative regulation of androgen receptor activity; IDA:UniProtKB.::GO:0060766; P:negative regulation of androgen receptor signaling pathway; IDA:UniProtKB.::GO:0007219; P:Notch signaling pathway; IDA:UniProtKB.::GO:0045666; P:positive regulation of neuron differentiation; ISS:UniProtKB.
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