Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Coccidiodis immitis RS
Locus:
CIMG_00161
Length:
1071
Number of sequences:
9910
Description:
HLH transcription factor
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
61B8XIA5    439   MYC_MACMU Myc proto-oncogene protein OS=Macac...1020.007     43.9     28     42GO:0005730; C:nucleolus; ISS:UniProtKB.
GO:0070888; F:E-box binding; ISS:UniProtKB.::GO:0032403; F:protein complex binding; ISS:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; ISS:UniProtKB.
GO:0060070; P:canonical Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0006879; P:cellular iron ion homeostasis; ISS:UniProtKB.::GO:0006338; P:chromatin remodeling; ISS:UniProtKB.::GO:0000165; P:MAPK cascade; ISS:UniProtKB.::GO:0051782; P:negative regulation of cell division; ISS:UniProtKB.::GO:0045656; P:negative regulation of monocyte differentiation; ISS:UniProtKB.::GO:0032873; P:negative regulation of stress-activated MAPK cascade; ISS:UniProtKB.::GO:2000573; P:positive regulation of DNA biosynthetic process; ISS:UniProtKB.::GO:0050679; P:positive regulation of epithelial cell proliferation; ISS:UniProtKB.::GO:0048146; P:positive regulation of fibroblast proliferation; ISS:UniProtKB.::GO:2001022; P:positive regulation of response to DNA damage stimulus; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0032204; P:regulation of telomere maintenance; ISS:UniProtKB.::GO:0006974; P:response to DNA damage stimulus; ISS:UniProtKB.::GO:0010332; P:response to gamma radiation; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
62Q9MZT6    438   MYC_SYLFL Myc proto-oncogene protein OS=Sylvi...1020.007     43.9     28     42GO:0005730; C:nucleolus; ISS:UniProtKB.::GO:0005654; C:nucleoplasm; ISS:UniProtKB.
GO:0070888; F:E-box binding; ISS:UniProtKB.::GO:0032403; F:protein complex binding; ISS:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; ISS:UniProtKB.
GO:0060070; P:canonical Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0006879; P:cellular iron ion homeostasis; ISS:UniProtKB.::GO:0006338; P:chromatin remodeling; ISS:UniProtKB.::GO:0000165; P:MAPK cascade; ISS:UniProtKB.::GO:0051782; P:negative regulation of cell division; ISS:UniProtKB.::GO:0045656; P:negative regulation of monocyte differentiation; ISS:UniProtKB.::GO:0043280; P:positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; ISS:UniProtKB.::GO:2000573; P:positive regulation of DNA biosynthetic process; ISS:UniProtKB.::GO:0050679; P:positive regulation of epithelial cell proliferation; ISS:UniProtKB.::GO:0048146; P:positive regulation of fibroblast proliferation; ISS:UniProtKB.::GO:2001022; P:positive regulation of response to DNA damage stimulus; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0032204; P:regulation of telomere maintenance; ISS:UniProtKB.::GO:0006974; P:response to DNA damage stimulus; ISS:UniProtKB.::GO:0010332; P:response to gamma radiation; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
63P01106    439   MYC_HUMAN Myc proto-oncogene protein OS=Homo ...1020.007     43.9     28     42GO:0005730; C:nucleolus; IDA:UniProtKB.::GO:0043234; C:protein complex; IDA:UniProtKB.
GO:0070888; F:E-box binding; IDA:UniProtKB.::GO:0032403; F:protein complex binding; IDA:UniProtKB.::GO:0070491; F:repressing transcription factor binding; IPI:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.
GO:0001658; P:branching involved in ureteric bud morphogenesis; ISS:UniProtKB.::GO:0060070; P:canonical Wnt receptor signaling pathway; IDA:UniProtKB.::GO:0007050; P:cell cycle arrest; IDA:UniProtKB.::GO:0006879; P:cellular iron ion homeostasis; IDA:UniProtKB.::GO:0035690; P:cellular response to drug; IDA:UniProtKB.::GO:0034644; P:cellular response to UV; IEP:UniProtKB.::GO:0006338; P:chromatin remodeling; IDA:UniProtKB.::GO:0006112; P:energy reserve metabolic process; NAS:UniProtKB.::GO:0044346; P:fibroblast apoptotic process; TAS:UniProtKB.::GO:0000165; P:MAPK cascade; IMP:UniProtKB.::GO:0051782; P:negative regulation of cell division; IDA:UniProtKB.::GO:0048147; P:negative regulation of fibroblast proliferation; IDA:UniProtKB.::GO:2001220; P:negative regulation of G2 phase of mitotic cell cycle; IDA:UniProtKB.::GO:0045656; P:negative regulation of monocyte differentiation; IMP:UniProtKB.::GO:0032873; P:negative regulation of stress-activated MAPK cascade; ISS:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0007219; P:Notch signaling pathway; TAS:Reactome.::GO:0015671; P:oxygen transport; NAS:UniProtKB.::GO:2000573; P:positive regulation of DNA biosynthetic process; IMP:UniProtKB.::GO:0050679; P:positive regulation of epithelial cell proliferation; IDA:UniProtKB.::GO:0048146; P:positive regulation of fibroblast proliferation; IDA:UniProtKB.::GO:0090096; P:positive regulation of metanephric cap mesenchymal cell proliferation; ISS:UniProtKB.::GO:2001022; P:positive regulation of response to DNA damage stimulus; IDA:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:UniProtKB.::GO:0032204; P:regulation of telomere maintenance; IMP:BHF-UCL.::GO:0006974; P:response to DNA damage stimulus; IDA:UniProtKB.::GO:0010332; P:response to gamma radiation; IDA:UniProtKB.::GO:0070848; P:response to growth factor stimulus; TAS:UniProtKB.
64P49032    438   MYC_CALJA Myc proto-oncogene protein OS=Calli...1020.007     43.9     28     42GO:0005730; C:nucleolus; ISS:UniProtKB.
GO:0070888; F:E-box binding; ISS:UniProtKB.::GO:0032403; F:protein complex binding; ISS:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; ISS:UniProtKB.
GO:0060070; P:canonical Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0006879; P:cellular iron ion homeostasis; ISS:UniProtKB.::GO:0006338; P:chromatin remodeling; ISS:UniProtKB.::GO:0000165; P:MAPK cascade; ISS:UniProtKB.::GO:0051782; P:negative regulation of cell division; ISS:UniProtKB.::GO:0045656; P:negative regulation of monocyte differentiation; ISS:UniProtKB.::GO:0032873; P:negative regulation of stress-activated MAPK cascade; ISS:UniProtKB.::GO:2000573; P:positive regulation of DNA biosynthetic process; ISS:UniProtKB.::GO:0050679; P:positive regulation of epithelial cell proliferation; ISS:UniProtKB.::GO:0048146; P:positive regulation of fibroblast proliferation; ISS:UniProtKB.::GO:2001022; P:positive regulation of response to DNA damage stimulus; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0032204; P:regulation of telomere maintenance; ISS:UniProtKB.::GO:0006974; P:response to DNA damage stimulus; ISS:UniProtKB.::GO:0010332; P:response to gamma radiation; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
65Q28566    439   MYC_SHEEP Myc proto-oncogene protein OS=Ovis ...1020.008     43.9     28     42GO:0016604; C:nuclear body; ISS:AgBase.::GO:0005730; C:nucleolus; ISS:UniProtKB.::GO:0005819; C:spindle; ISS:AgBase.
GO:0070888; F:E-box binding; ISS:UniProtKB.::GO:0032403; F:protein complex binding; ISS:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; ISS:UniProtKB.
GO:0006919; P:activation of cysteine-type endopeptidase activity involved in apoptotic process; ISS:AgBase.::GO:0008633; P:activation of pro-apoptotic gene products; ISS:AgBase.::GO:0060070; P:canonical Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0006879; P:cellular iron ion homeostasis; ISS:UniProtKB.::GO:0006338; P:chromatin remodeling; ISS:UniProtKB.::GO:0006309; P:DNA fragmentation involved in apoptotic nuclear change; ISS:AgBase.::GO:0008629; P:induction of apoptosis by intracellular signals; ISS:AgBase.::GO:0000165; P:MAPK cascade; ISS:UniProtKB.::GO:0051782; P:negative regulation of cell division; ISS:UniProtKB.::GO:0045656; P:negative regulation of monocyte differentiation; ISS:UniProtKB.::GO:0032873; P:negative regulation of stress-activated MAPK cascade; ISS:UniProtKB.::GO:0008634; P:negative regulation of survival gene product expression; ISS:AgBase.::GO:2000573; P:positive regulation of DNA biosynthetic process; ISS:UniProtKB.::GO:0050679; P:positive regulation of epithelial cell proliferation; ISS:UniProtKB.::GO:0048146; P:positive regulation of fibroblast proliferation; ISS:UniProtKB.::GO:2001022; P:positive regulation of response to DNA damage stimulus; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0032204; P:regulation of telomere maintenance; ISS:UniProtKB.::GO:0001836; P:release of cytochrome c from mitochondria; ISS:AgBase.::GO:0006974; P:response to DNA damage stimulus; ISS:UniProtKB.::GO:0042493; P:response to drug; ISS:UniProtKB.::GO:0010332; P:response to gamma radiation; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
66P68272    439   MYC_FLV Viral myc transforming protein OS=Fel...1020.009     43.5     28     42GO:0042025; C:host cell nucleus; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0070888; F:E-box binding; ISS:UniProtKB.::GO:0032403; F:protein complex binding; ISS:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; ISS:UniProtKB.
GO:0060070; P:canonical Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0006879; P:cellular iron ion homeostasis; ISS:UniProtKB.::GO:0006338; P:chromatin remodeling; ISS:UniProtKB.::GO:0000165; P:MAPK cascade; ISS:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0051782; P:negative regulation of cell division; ISS:UniProtKB.::GO:0045656; P:negative regulation of monocyte differentiation; ISS:UniProtKB.::GO:0032873; P:negative regulation of stress-activated MAPK cascade; ISS:UniProtKB.::GO:0043280; P:positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; ISS:UniProtKB.::GO:2000573; P:positive regulation of DNA biosynthetic process; ISS:UniProtKB.::GO:0050679; P:positive regulation of epithelial cell proliferation; ISS:UniProtKB.::GO:0048146; P:positive regulation of fibroblast proliferation; ISS:UniProtKB.::GO:2001022; P:positive regulation of response to DNA damage stimulus; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0032204; P:regulation of telomere maintenance; ISS:UniProtKB.::GO:0006974; P:response to DNA damage stimulus; ISS:UniProtKB.::GO:0042493; P:response to drug; ISS:UniProtKB.::GO:0010332; P:response to gamma radiation; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
67P68271    439   MYC_FELCA Myc proto-oncogene protein OS=Felis...1020.009     43.5     28     42GO:0005730; C:nucleolus; ISS:UniProtKB.
GO:0070888; F:E-box binding; ISS:UniProtKB.::GO:0032403; F:protein complex binding; ISS:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; ISS:UniProtKB.
GO:0060070; P:canonical Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0006879; P:cellular iron ion homeostasis; ISS:UniProtKB.::GO:0006338; P:chromatin remodeling; ISS:UniProtKB.::GO:0000165; P:MAPK cascade; ISS:UniProtKB.::GO:0051782; P:negative regulation of cell division; ISS:UniProtKB.::GO:0045656; P:negative regulation of monocyte differentiation; ISS:UniProtKB.::GO:0032873; P:negative regulation of stress-activated MAPK cascade; ISS:UniProtKB.::GO:2000573; P:positive regulation of DNA biosynthetic process; ISS:UniProtKB.::GO:0050679; P:positive regulation of epithelial cell proliferation; ISS:UniProtKB.::GO:0048146; P:positive regulation of fibroblast proliferation; ISS:UniProtKB.::GO:2001022; P:positive regulation of response to DNA damage stimulus; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0032204; P:regulation of telomere maintenance; ISS:UniProtKB.::GO:0006974; P:response to DNA damage stimulus; ISS:UniProtKB.::GO:0010332; P:response to gamma radiation; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
68P01108    439   MYC_MOUSE Myc proto-oncogene protein OS=Mus m...1020.011     43.1     28     41GO:0030424; C:axon; IDA:MGI.::GO:0016604; C:nuclear body; IDA:MGI.::GO:0005730; C:nucleolus; ISS:UniProtKB.::GO:0005819; C:spindle; IDA:MGI.
GO:0070888; F:E-box binding; ISS:UniProtKB.::GO:0032403; F:protein complex binding; ISS:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; ISS:UniProtKB.
GO:0006919; P:activation of cysteine-type endopeptidase activity involved in apoptotic process; IDA:MGI.::GO:0008633; P:activation of pro-apoptotic gene products; IDA:MGI.::GO:0001783; P:B cell apoptotic process; IMP:MGI.::GO:0001658; P:branching involved in ureteric bud morphogenesis; IMP:UniProtKB.::GO:0060070; P:canonical Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0006879; P:cellular iron ion homeostasis; ISS:UniProtKB.::GO:0035690; P:cellular response to drug; IDA:UniProtKB.::GO:0006338; P:chromatin remodeling; ISS:UniProtKB.::GO:0050910; P:detection of mechanical stimulus involved in sensory perception of sound; IMP:MGI.::GO:0006309; P:DNA fragmentation involved in apoptotic nuclear change; IDA:MGI.::GO:0008629; P:induction of apoptosis by intracellular signals; IDA:MGI.::GO:0000165; P:MAPK cascade; ISS:UniProtKB.::GO:0042474; P:middle ear morphogenesis; IMP:MGI.::GO:0051782; P:negative regulation of cell division; ISS:UniProtKB.::GO:0045656; P:negative regulation of monocyte differentiation; ISS:UniProtKB.::GO:0032091; P:negative regulation of protein binding; IDA:MGI.::GO:0008634; P:negative regulation of survival gene product expression; IDA:MGI.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:MGI.::GO:0043473; P:pigmentation; IMP:MGI.::GO:0002904; P:positive regulation of B cell apoptotic process; IGI:MGI.::GO:2000573; P:positive regulation of DNA biosynthetic process; ISS:UniProtKB.::GO:0050679; P:positive regulation of epithelial cell proliferation; ISS:UniProtKB.::GO:0048146; P:positive regulation of fibroblast proliferation; ISS:UniProtKB.::GO:0090096; P:positive regulation of metanephric cap mesenchymal cell proliferation; IMP:UniProtKB.::GO:2001022; P:positive regulation of response to DNA damage stimulus; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:MGI.::GO:0016485; P:protein processing; IMP:MGI.::GO:0032204; P:regulation of telomere maintenance; ISS:UniProtKB.::GO:0001836; P:release of cytochrome c from mitochondria; IDA:MGI.::GO:0043279; P:response to alkaloid; IMP:MGI.::GO:0006974; P:response to DNA damage stimulus; ISS:UniProtKB.::GO:0010332; P:response to gamma radiation; ISS:UniProtKB.::GO:0048705; P:skeletal system morphogenesis; IMP:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
69Q8AXV6    317   HEY1_DANRE Hairy/enhancer-of-split related wi...1020.011     42.7     30     42GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0007219; P:Notch signaling pathway; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
70P10166    368   MYCL1_MOUSE Protein L-Myc-1 OS=Mus musculus (...870.013     42.7     30     47GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:MGI.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
71P06646    414   MYC_ONCMY Transcriptional regulator Myc OS=On...1070.022     42.4     29     44GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
72P09416    439   MYC_RAT Myc proto-oncogene protein OS=Rattus ...1020.022     42.4     28     41GO:0005737; C:cytoplasm; IDA:RGD.::GO:0005730; C:nucleolus; ISS:UniProtKB.
GO:0003690; F:double-stranded DNA binding; IDA:RGD.::GO:0070888; F:E-box binding; ISS:UniProtKB.::GO:0032403; F:protein complex binding; ISS:UniProtKB.::GO:0046982; F:protein heterodimerization activity; IPI:RGD.::GO:0043565; F:sequence-specific DNA binding; IDA:RGD.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:RGD.
GO:0001658; P:branching involved in ureteric bud morphogenesis; ISS:UniProtKB.::GO:0060070; P:canonical Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0006879; P:cellular iron ion homeostasis; ISS:UniProtKB.::GO:0006338; P:chromatin remodeling; ISS:UniProtKB.::GO:0006006; P:glucose metabolic process; IMP:RGD.::GO:0000165; P:MAPK cascade; ISS:UniProtKB.::GO:0051782; P:negative regulation of cell division; ISS:UniProtKB.::GO:0045656; P:negative regulation of monocyte differentiation; ISS:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:UniProtKB.::GO:0009405; P:pathogenesis; TAS:RGD.::GO:2000573; P:positive regulation of DNA biosynthetic process; ISS:UniProtKB.::GO:0050679; P:positive regulation of epithelial cell proliferation; ISS:UniProtKB.::GO:0048146; P:positive regulation of fibroblast proliferation; ISS:UniProtKB.::GO:0090096; P:positive regulation of metanephric cap mesenchymal cell proliferation; ISS:UniProtKB.::GO:2001022; P:positive regulation of response to DNA damage stimulus; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:RGD.::GO:0032204; P:regulation of telomere maintenance; ISS:UniProtKB.::GO:0006974; P:response to DNA damage stimulus; ISS:UniProtKB.::GO:0010332; P:response to gamma radiation; ISS:UniProtKB.::GO:0006366; P:transcription from RNA polymerase II promoter; IDA:RGD.::GO:0006352; P:transcription initiation, DNA-dependent; IDA:RGD.
73O35779    410   BHE41_RAT Class E basic helix-loop-helix prot...1060.023     42     27     45GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
GO:0009649; P:entrainment of circadian clock; IDA:RGD.::GO:0007399; P:nervous system development; NAS:RGD.::GO:0048168; P:regulation of neuronal synaptic plasticity; IEP:RGD.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
74Q2KIN4    304   HEY1_BOVIN Hairy/enhancer-of-split related wi...1030.023     42     30     45GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003198; P:epithelial to mesenchymal transition involved in endocardial cushion formation; ISS:UniProtKB.::GO:0007219; P:Notch signaling pathway; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
75Q17103    407   MYC_ASTRU Myc protein OS=Asterias rubens (Com...1220.023     42     29     43GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
76Q9TSZ2    304   HEY1_CANFA Hairy/enhancer-of-split related wi...1230.024     41.6     28     42GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003198; P:epithelial to mesenchymal transition involved in endocardial cushion formation; ISS:UniProtKB.::GO:0007219; P:Notch signaling pathway; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
77P52160    408   MYCA_DANRE Transcriptional regulator Myc-A OS...1070.027     42     29     44GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0003677; F:DNA binding; ISS:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:UniProtKB.
GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
78Q99PV5    410   BHE41_MOUSE Class E basic helix-loop-helix pr...1060.028     42     27     45GO:0017053; C:transcriptional repressor complex; TAS:MGI.
GO:0070888; F:E-box binding; IDA:BHF-UCL.::GO:0042826; F:histone deacetylase binding; IDA:BHF-UCL.::GO:0043426; F:MRF binding; IDA:BHF-UCL.::GO:0046982; F:protein heterodimerization activity; IDA:BHF-UCL.::GO:0042803; F:protein homodimerization activity; IPI:BHF-UCL.::GO:0001102; F:RNA polymerase II activating transcription factor binding; IDA:BHF-UCL.::GO:0000978; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding; IDA:BHF-UCL.::GO:0001078; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription; IDA:BHF-UCL.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IDA:BHF-UCL.::GO:0001191; F:RNA polymerase II transcription factor binding transcription factor activity involved in negative regulation of transcription; IDA:BHF-UCL.::GO:0003714; F:transcription corepressor activity; TAS:MGI.
GO:0032922; P:circadian regulation of gene expression; IMP:BHF-UCL.::GO:0010832; P:negative regulation of myotube differentiation; IDA:BHF-UCL.::GO:0010944; P:negative regulation of transcription by competitive promoter binding; IDA:BHF-UCL.
79Q9Y5J3    304   HEY1_HUMAN Hairy/enhancer-of-split related wi...1030.029     41.6     30     45GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0035939; F:microsatellite binding; IDA:UniProtKB.::GO:0000988; F:protein binding transcription factor activity; IDA:UniProtKB.::GO:0000983; F:RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity; ISS:UniProtKB.::GO:0008134; F:transcription factor binding; NAS:UniProtKB.
GO:0001525; P:angiogenesis; IEP:UniProtKB.::GO:0003198; P:epithelial to mesenchymal transition involved in endocardial cushion formation; ISS:UniProtKB.::GO:0045746; P:negative regulation of Notch signaling pathway; IDA:BHF-UCL.::GO:2000820; P:negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation; IDA:BHF-UCL.::GO:2000678; P:negative regulation of transcription regulatory region DNA binding; IDA:BHF-UCL.::GO:0007219; P:Notch signaling pathway; IDA:UniProtKB.
80Q29031    439   MYC_PIG Myc proto-oncogene protein OS=Sus scr...1020.03     42     27     41GO:0016604; C:nuclear body; ISS:AgBase.::GO:0005730; C:nucleolus; ISS:UniProtKB.::GO:0005819; C:spindle; ISS:AgBase.
GO:0070888; F:E-box binding; ISS:UniProtKB.::GO:0032403; F:protein complex binding; ISS:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; ISS:UniProtKB.
GO:0006919; P:activation of cysteine-type endopeptidase activity involved in apoptotic process; ISS:AgBase.::GO:0008633; P:activation of pro-apoptotic gene products; ISS:AgBase.::GO:0060070; P:canonical Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0006879; P:cellular iron ion homeostasis; ISS:UniProtKB.::GO:0006338; P:chromatin remodeling; ISS:UniProtKB.::GO:0006309; P:DNA fragmentation involved in apoptotic nuclear change; ISS:AgBase.::GO:0008629; P:induction of apoptosis by intracellular signals; ISS:AgBase.::GO:0000165; P:MAPK cascade; ISS:UniProtKB.::GO:0051782; P:negative regulation of cell division; ISS:UniProtKB.::GO:0045656; P:negative regulation of monocyte differentiation; ISS:UniProtKB.::GO:0032873; P:negative regulation of stress-activated MAPK cascade; ISS:UniProtKB.::GO:0008634; P:negative regulation of survival gene product expression; ISS:AgBase.::GO:2000573; P:positive regulation of DNA biosynthetic process; ISS:UniProtKB.::GO:0050679; P:positive regulation of epithelial cell proliferation; ISS:UniProtKB.::GO:0048146; P:positive regulation of fibroblast proliferation; ISS:UniProtKB.::GO:2001022; P:positive regulation of response to DNA damage stimulus; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0032204; P:regulation of telomere maintenance; ISS:UniProtKB.::GO:0001836; P:release of cytochrome c from mitochondria; ISS:AgBase.::GO:0006974; P:response to DNA damage stimulus; ISS:UniProtKB.::GO:0042493; P:response to drug; ISS:UniProtKB.::GO:0010332; P:response to gamma radiation; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
81Q90342    401   MYC2_CYPCA Transcriptional regulator Myc-2 OS...1070.031     41.6     29     44GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
82P49709    399   MYC_CARAU Transcriptional regulator Myc OS=Ca...1070.038     41.2     29     44GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
83Q9FN69    637   GL3_ARATH Transcription factor GLABRA 3 OS=Ar...800.05     41.2     31     44GO:0005634; C:nucleus; IDA:TAIR.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0009957; P:epidermal cell fate specification; IMP:TAIR.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0010091; P:trichome branching; IMP:TAIR.
84Q8AXV5    310   HEYL_DANRE Hairy/enhancer-of-split related wi...1000.057     40.4     31     45GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0007219; P:Notch signaling pathway; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
85Q9C0J9    482   BHE41_HUMAN Class E basic helix-loop-helix pr...1060.066     40.8     27     45GO:0005634; C:nucleus; NAS:UniProtKB.
GO:0070888; F:E-box binding; IDA:BHF-UCL.::GO:0042826; F:histone deacetylase binding; ISS:BHF-UCL.::GO:0043426; F:MRF binding; ISS:BHF-UCL.::GO:0046982; F:protein heterodimerization activity; ISS:BHF-UCL.::GO:0042803; F:protein homodimerization activity; ISS:BHF-UCL.::GO:0001102; F:RNA polymerase II activating transcription factor binding; ISS:BHF-UCL.::GO:0000978; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding; ISS:BHF-UCL.::GO:0001078; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription; ISS:BHF-UCL.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; ISS:BHF-UCL.::GO:0001191; F:RNA polymerase II transcription factor binding transcription factor activity involved in negative regulation of transcription; ISS:BHF-UCL.
GO:0030154; P:cell differentiation; NAS:UniProtKB.::GO:0008283; P:cell proliferation; NAS:UniProtKB.::GO:0010832; P:negative regulation of myotube differentiation; ISS:BHF-UCL.::GO:0010944; P:negative regulation of transcription by competitive promoter binding; ISS:BHF-UCL.::GO:0009887; P:organ morphogenesis; NAS:UniProtKB.
86Q9FT81    518   TT8_ARATH Transcription factor TT8 OS=Arabido...880.075     40.4     32     39GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0009813; P:flavonoid biosynthetic process; IEA:UniProtKB-KW.::GO:2000029; P:regulation of proanthocyanidin biosynthetic process; IEP:TAIR.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0010026; P:trichome differentiation; IMP:TAIR.
87Q7ZVS9    396   MYCB_DANRE Transcriptional regulator Myc-B OS...1040.077     40.4     30     45GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
88Q90341    394   MYC1_CYPCA Transcriptional regulator Myc-1 OS...950.1     40     28     46GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
89Q9R210    475   TFEB_MOUSE Transcription factor EB OS=Mus mus...1070.11     40     28     45GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005667; C:transcription factor complex; IDA:MGI.
GO:0046982; F:protein heterodimerization activity; IPI:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.::GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB.
GO:0001892; P:embryonic placenta development; IMP:UniProtKB.::GO:0006959; P:humoral immune response; IMP:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
90Q07016    163   MAX_XENLA Protein max OS=Xenopus laevis (Afri...790.12     38.5     29     47GO:0071339; C:MLL1 complex; ISS:UniProtKB.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
91P21438    437   MYC_FLVTT Viral myc transforming protein OS=F...1020.12     39.7     27     41GO:0042025; C:host cell nucleus; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:InterPro.
GO:0070888; F:E-box binding; ISS:UniProtKB.::GO:0032403; F:protein complex binding; ISS:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; ISS:UniProtKB.
GO:0060070; P:canonical Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0006879; P:cellular iron ion homeostasis; ISS:UniProtKB.::GO:0006338; P:chromatin remodeling; ISS:UniProtKB.::GO:0000165; P:MAPK cascade; ISS:UniProtKB.::GO:0051782; P:negative regulation of cell division; ISS:UniProtKB.::GO:0045656; P:negative regulation of monocyte differentiation; ISS:UniProtKB.::GO:0043280; P:positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; ISS:UniProtKB.::GO:2000573; P:positive regulation of DNA biosynthetic process; ISS:UniProtKB.::GO:0050679; P:positive regulation of epithelial cell proliferation; ISS:UniProtKB.::GO:0048146; P:positive regulation of fibroblast proliferation; ISS:UniProtKB.::GO:2001022; P:positive regulation of response to DNA damage stimulus; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0032204; P:regulation of telomere maintenance; ISS:UniProtKB.::GO:0006974; P:response to DNA damage stimulus; ISS:UniProtKB.::GO:0010332; P:response to gamma radiation; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
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