| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | P47125 | 453 | I23O_YEAST Indoleamine 2,3-dioxygenase family... | 441 | 2e-94 | 300 | 40 | 55 | GO:0005737; C:cytoplasm; IDA:SGD. | | | | | | | | | | GO:0020037; F:heme binding; IEA:InterPro.::GO:0033754; F:indoleamine 2,3-dioxygenase activity; NAS:SGD.::GO:0004833; F:tryptophan 2,3-dioxygenase activity; NAS:SGD. | | | | | | | | | | GO:0034354; P:de novo NAD biosynthetic process from tryptophan; IGI:SGD. | 2 | P28776 | 407 | I23O1_MOUSE Indoleamine 2,3-dioxygenase 1 OS=... | 431 | 5e-55 | 194 | 32 | 52 | GO:0030485; C:smooth muscle contractile fiber; IDA:MGI.::GO:0032421; C:stereocilium bundle; IDA:MGI. | | | | | | | | | | GO:0020037; F:heme binding; IEA:InterPro.::GO:0033754; F:indoleamine 2,3-dioxygenase activity; IEA:EC.::GO:0004833; F:tryptophan 2,3-dioxygenase activity; IDA:MGI. | | | | | | | | | | GO:0007610; P:behavior; IMP:MGI.::GO:0002534; P:cytokine production involved in inflammatory response; IMP:MGI.::GO:0034276; P:kynurenic acid biosynthetic process; IMP:MGI.::GO:0033555; P:multicellular organismal response to stress; IMP:MGI.::GO:0046007; P:negative regulation of activated T cell proliferation; IMP:MGI.::GO:0032693; P:negative regulation of interleukin-10 production; IMP:MGI.::GO:0070233; P:negative regulation of T cell apoptotic process; IMP:MGI.::GO:0043065; P:positive regulation of apoptotic process; IMP:MGI.::GO:0002678; P:positive regulation of chronic inflammatory response; IMP:MGI.::GO:0032735; P:positive regulation of interleukin-12 production; IMP:MGI.::GO:0002666; P:positive regulation of T cell tolerance induction; IMP:MGI.::GO:0002830; P:positive regulation of type 2 immune response; IMP:MGI.::GO:0032496; P:response to lipopolysaccharide; IMP:MGI.::GO:0019441; P:tryptophan catabolic process to kynurenine; IDA:MGI. | 3 | Q8R0V5 | 398 | I23O2_MOUSE Indoleamine 2,3-dioxygenase 2 OS=... | 428 | 8e-55 | 194 | 32 | 50 | | | | | | | | | | | GO:0020037; F:heme binding; IEA:InterPro.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW. | | | | | | | | | | | 4 | Q6ZQW0 | 407 | I23O2_HUMAN Indoleamine 2,3-dioxygenase 2 OS=... | 431 | 1e-54 | 194 | 32 | 50 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0020037; F:heme binding; IEA:InterPro.::GO:0033754; F:indoleamine 2,3-dioxygenase activity; IDA:UniProtKB.::GO:0004833; F:tryptophan 2,3-dioxygenase activity; EXP:Reactome. | | | | | | | | | | GO:0019441; P:tryptophan catabolic process to kynurenine; IDA:UniProtKB. | 5 | Q9ERD9 | 407 | I23O1_RAT Indoleamine 2,3-dioxygenase 1 OS=Ra... | 428 | 1e-54 | 194 | 32 | 51 | GO:0005829; C:cytosol; IDA:RGD.::GO:0005625; C:soluble fraction; IDA:RGD. | | | | | | | | | | GO:0016597; F:amino acid binding; IDA:RGD.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0033754; F:indoleamine 2,3-dioxygenase activity; IDA:RGD.::GO:0019825; F:oxygen binding; IDA:RGD. | | | | | | | | | | GO:0019441; P:tryptophan catabolic process to kynurenine; IDA:RGD. | 6 | P14902 | 403 | I23O1_HUMAN Indoleamine 2,3-dioxygenase 1 OS=... | 429 | 3e-44 | 165 | 28 | 49 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0009055; F:electron carrier activity; TAS:UniProtKB.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0033754; F:indoleamine 2,3-dioxygenase activity; IEA:EC.::GO:0004833; F:tryptophan 2,3-dioxygenase activity; EXP:Reactome. | | | | | | | | | | GO:0007565; P:female pregnancy; TAS:ProtInc.::GO:0006569; P:tryptophan catabolic process; TAS:Reactome. | 7 | P51537 | 378 | MYG_HALMK Myoglobin OS=Haliotis madaka (Giant... | 423 | 1e-40 | 154 | 28 | 43 | | | | | | | | | | | GO:0020037; F:heme binding; IEA:InterPro.::GO:0005344; F:oxygen transporter activity; IEA:UniProtKB-KW. | | | | | | | | | | | 8 | Q01966 | 378 | MYG_HALDV Myoglobin OS=Haliotis diversicolor ... | 426 | 9e-39 | 149 | 28 | 43 | | | | | | | | | | | GO:0020037; F:heme binding; IEA:InterPro.::GO:0005344; F:oxygen transporter activity; IEA:UniProtKB-KW. | | | | | | | | | | | 9 | Q11U61 | 717 | PNP_CYTH3 Polyribonucleotide nucleotidyltrans... | 72 | 3.3 | 33.9 | 28 | 50 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000175; F:3'-5'-exoribonuclease activity; IEA:InterPro.::GO:0004654; F:polyribonucleotide nucleotidyltransferase activity; IEA:EC.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006402; P:mRNA catabolic process; IEA:InterPro.::GO:0006396; P:RNA processing; IEA:InterPro. | 10 | P13458 | 1048 | SBCC_ECOLI Nuclease sbcCD subunit C OS=Escher... | 37 | 5.4 | 33.5 | 43 | 70 | | | | | | | | | | | GO:0008296; F:3'-5'-exodeoxyribonuclease activity; IDA:EcoCyc.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006260; P:DNA replication; IEA:UniProtKB-KW.::GO:0000725; P:recombinational repair; IDA:EcoCyc. | 11 | Q09600 | 980 | VPS11_CAEEL Vacuolar protein sorting-associat... | 83 | 9.2 | 32.7 | 27 | 45 | GO:0005774; C:vacuolar membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0010171; P:body morphogenesis; IMP:WormBase.::GO:0008219; P:cell death; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040007; P:growth; IMP:WormBase.::GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0018996; P:molting cycle, collagen and cuticulin-based cuticle; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0040010; P:positive regulation of growth rate; IMP:WormBase.::GO:0040018; P:positive regulation of multicellular organism growth; IMP:WormBase.::GO:0000003; P:reproduction; IMP:WormBase.::GO:0071688; P:striated muscle myosin thick filament assembly; IMP:WormBase.::GO:0016192; P:vesicle-mediated transport; IEA:InterPro. |
