rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | Q12324 | 675 | YVC1_YEAST Calcium channel YVC1 OS=Saccharomy... | 548 | 2e-126 | 395 | 38 | 62 | GO:0000329; C:fungal-type vacuole membrane; IDA:SGD.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005227; F:calcium activated cation channel activity; IDA:SGD.::GO:0005262; F:calcium channel activity; IDA:SGD.::GO:0005267; F:potassium channel activity; IDA:SGD.::GO:0005272; F:sodium channel activity; IDA:SGD.::GO:0005244; F:voltage-gated ion channel activity; IDA:SGD. | | | | | | | | | | GO:0030003; P:cellular cation homeostasis; IDA:SGD. | 2 | Q9Y210 | 931 | TRPC6_HUMAN Short transient receptor potentia... | 268 | 0.000002 | 54.7 | 23 | 41 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IDA:MGI. | | | | | | | | | | GO:0070679; F:inositol 1,4,5 trisphosphate binding; IDA:BHF-UCL.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0007411; P:axon guidance; TAS:Reactome.::GO:0030168; P:platelet activation; TAS:Reactome.::GO:0032236; P:positive regulation of calcium ion transport via store-operated calcium channel activity; IDA:MGI. | 3 | Q61143 | 930 | TRPC6_MOUSE Short transient receptor potentia... | 268 | 0.000002 | 54.7 | 23 | 41 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IDA:MGI.::GO:0036057; C:slit diaphragm; IDA:MGI. | | | | | | | | | | GO:0005515; F:protein binding; IPI:MGI.::GO:0015279; F:store-operated calcium channel activity; IDA:MGI. | | | | | | | | | | GO:0007204; P:elevation of cytosolic calcium ion concentration; IDA:MGI. | 4 | Q91YD4 | 1507 | TRPM2_MOUSE Transient receptor potential cati... | 253 | 0.00007 | 50.1 | 22 | 40 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IDA:MGI. | | | | | | | | | | GO:0047631; F:ADP-ribose diphosphatase activity; IEA:EC.::GO:0005262; F:calcium channel activity; IEA:UniProtKB-KW.::GO:0005384; F:manganese ion transmembrane transporter activity; IDA:MGI.::GO:0005272; F:sodium channel activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0033194; P:response to hydroperoxide; IDA:MGI. | 5 | Q9HCX4 | 862 | TRPC7_HUMAN Short transient receptor potentia... | 280 | 0.001 | 45.4 | 22 | 39 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005635; C:nuclear envelope; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; TAS:Reactome. | | | | | | | | | | GO:0005262; F:calcium channel activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007411; P:axon guidance; TAS:Reactome.::GO:0030168; P:platelet activation; TAS:Reactome. | 6 | Q9WVC5 | 862 | TRPC7_MOUSE Short transient receptor potentia... | 280 | 0.002 | 45.4 | 21 | 39 | GO:0016021; C:integral to membrane; IC:MGI.::GO:0005635; C:nuclear envelope; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005262; F:calcium channel activity; IDA:MGI. | | | | | | | | | | GO:0006828; P:manganese ion transport; IDA:MGI. | 7 | O94759 | 1503 | TRPM2_HUMAN Transient receptor potential cati... | 163 | 0.003 | 44.7 | 26 | 41 | GO:0005887; C:integral to plasma membrane; TAS:ProtInc. | | | | | | | | | | GO:0047631; F:ADP-ribose diphosphatase activity; IEA:EC.::GO:0005262; F:calcium channel activity; TAS:ProtInc.::GO:0005272; F:sodium channel activity; IEA:UniProtKB-KW. | | | | | | | | | | | 8 | Q9JMI9 | 836 | TRPC3_RAT Short transient receptor potential ... | 234 | 0.004 | 44.3 | 24 | 41 | | | | | | | | | | | GO:0005227; F:calcium activated cation channel activity; IDA:RGD.::GO:0005262; F:calcium channel activity; IEA:UniProtKB-KW. | | | | | | | | | | | 9 | Q9QZC1 | 836 | TRPC3_MOUSE Short transient receptor potentia... | 234 | 0.004 | 44.3 | 24 | 41 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005262; F:calcium channel activity; IEA:UniProtKB-KW. | | | | | | | | | | | 10 | Q13507 | 836 | TRPC3_HUMAN Short transient receptor potentia... | 233 | 0.004 | 43.9 | 23 | 41 | GO:0005887; C:integral to plasma membrane; IDA:MGI. | | | | | | | | | | GO:0070679; F:inositol 1,4,5 trisphosphate binding; IDA:BHF-UCL.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0015279; F:store-operated calcium channel activity; TAS:ProtInc. | | | | | | | | | | GO:0007411; P:axon guidance; TAS:Reactome.::GO:0007602; P:phototransduction; TAS:ProtInc.::GO:0030168; P:platelet activation; TAS:Reactome.::GO:0010524; P:positive regulation of calcium ion transport into cytosol; IDA:UniProtKB.::GO:0033198; P:response to ATP; IDA:UniProtKB.::GO:0051592; P:response to calcium ion; IDA:UniProtKB. | 11 | Q9VJJ7 | 1128 | TRPG_DROME Transient receptor potential-gamma... | 287 | 0.02 | 42 | 22 | 39 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0016028; C:rhabdomere; IDA:UniProtKB. | | | | | | | | | | GO:0005262; F:calcium channel activity; ISS:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0050908; P:detection of light stimulus involved in visual perception; ISS:UniProtKB. | 12 | Q9R244 | 1172 | TRPC2_MOUSE Short transient receptor potentia... | 173 | 0.02 | 42 | 25 | 46 | GO:0032590; C:dendrite membrane; IMP:MGI.::GO:0005789; C:endoplasmic reticulum membrane; IDA:MGI.::GO:0000139; C:Golgi membrane; IDA:MGI.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005635; C:nuclear envelope; IDA:MGI.::GO:0005634; C:nucleus; IEA:InterPro. | | | | | | | | | | GO:0005262; F:calcium channel activity; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IDA:MGI.::GO:0003684; F:damaged DNA binding; IEA:InterPro.::GO:0019992; F:diacylglycerol binding; IMP:MGI.::GO:0070679; F:inositol 1,4,5 trisphosphate binding; IDA:BHF-UCL.::GO:0005515; F:protein binding; IPI:BHF-UCL.::GO:0015279; F:store-operated calcium channel activity; IDA:MGI. | | | | | | | | | | GO:0007340; P:acrosome reaction; IMP:MGI.::GO:0007204; P:elevation of cytosolic calcium ion concentration; IPI:MGI.::GO:0008050; P:female courtship behavior; IMP:MGI.::GO:0002121; P:inter-male aggressive behavior; IMP:MGI.::GO:0048047; P:mating behavior, sex discrimination; IMP:MGI.::GO:0019236; P:response to pheromone; IMP:MGI.::GO:0000012; P:single strand break repair; IEA:InterPro.::GO:0002124; P:territorial aggressive behavior; IMP:MGI. | 13 | Q9QX29 | 975 | TRPC5_MOUSE Short transient receptor potentia... | 269 | 0.027 | 41.6 | 22 | 40 | GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005262; F:calcium channel activity; IEA:UniProtKB-KW.::GO:0070679; F:inositol 1,4,5 trisphosphate binding; IDA:BHF-UCL.::GO:0005515; F:protein binding; IPI:BHF-UCL. | | | | | | | | | | | 14 | O62852 | 974 | TRPC5_RABIT Short transient receptor potentia... | 269 | 0.028 | 41.2 | 22 | 40 | GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005262; F:calcium channel activity; IEA:UniProtKB-KW. | | | | | | | | | | | 15 | P48994 | 1124 | TRPL_DROME Transient-receptor-potential-like ... | 281 | 0.03 | 41.2 | 20 | 43 | GO:0016027; C:inaD signaling complex; IPI:UniProtKB.::GO:0016021; C:integral to membrane; NAS:UniProtKB.::GO:0005622; C:intracellular; IDA:UniProtKB. | | | | | | | | | | GO:0005516; F:calmodulin binding; IDA:UniProtKB.::GO:0046982; F:protein heterodimerization activity; IPI:UniProtKB.::GO:0015279; F:store-operated calcium channel activity; NAS:FlyBase. | | | | | | | | | | GO:0007589; P:body fluid secretion; IMP:FlyBase.::GO:0019722; P:calcium-mediated signaling; IMP:FlyBase.::GO:0071454; P:cellular response to anoxia; IGI:FlyBase.::GO:0050908; P:detection of light stimulus involved in visual perception; ISS:UniProtKB. | 16 | Q9UL62 | 973 | TRPC5_HUMAN Short transient receptor potentia... | 269 | 0.034 | 41.2 | 22 | 40 | GO:0034704; C:calcium channel complex; IDA:UniProtKB.::GO:0005887; C:integral to plasma membrane; TAS:ProtInc. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0015279; F:store-operated calcium channel activity; TAS:ProtInc. | | | | | | | | | | GO:0007411; P:axon guidance; TAS:Reactome. | 17 | Q9R283 | 1170 | TRPC2_RAT Short transient receptor potential ... | 168 | 0.043 | 40.8 | 24 | 45 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0003684; F:damaged DNA binding; IEA:InterPro. | | | | | | | | | | GO:0000012; P:single strand break repair; IEA:InterPro. | 18 | Q8R455 | 1104 | TRPM8_RAT Transient receptor potential cation... | 221 | 0.075 | 40 | 24 | 38 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | | | | | | | | | | | GO:0009409; P:response to cold; IDA:RGD. | 19 | Q8R4D5 | 1104 | TRPM8_MOUSE Transient receptor potential cati... | 243 | 0.11 | 39.7 | 21 | 38 | GO:0009897; C:external side of plasma membrane; IDA:MGI.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005262; F:calcium channel activity; IDA:MGI.::GO:0042803; F:protein homodimerization activity; IPI:MGI. | | | | | | | | | | GO:0006874; P:cellular calcium ion homeostasis; IDA:MGI.::GO:0051289; P:protein homotetramerization; IDA:MGI.::GO:0070207; P:protein homotrimerization; IDA:MGI.::GO:0009409; P:response to cold; IDA:MGI.::GO:0050955; P:thermoception; IDA:MGI. | 20 | O62826 | 432 | TRPC2_BOVIN Short transient receptor potentia... | 178 | 0.14 | 38.9 | 25 | 45 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005262; F:calcium channel activity; IEA:UniProtKB-KW. | | | | | | | | | | | 21 | Q6RI86 | 1125 | TRPA1_RAT Transient receptor potential cation... | 243 | 0.16 | 38.9 | 25 | 43 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | | | | | | | | | | | | 22 | Q7Z2W7 | 1104 | TRPM8_HUMAN Transient receptor potential cati... | 221 | 0.17 | 38.9 | 23 | 38 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | | | | | | | | | | | | 23 | Q9UBN4 | 977 | TRPC4_HUMAN Short transient receptor potentia... | 265 | 0.39 | 37.7 | 21 | 41 | GO:0016323; C:basolateral plasma membrane; IDA:BHF-UCL.::GO:0034704; C:calcium channel complex; IDA:UniProtKB.::GO:0009986; C:cell surface; IDA:BHF-UCL.::GO:0030863; C:cortical cytoskeleton; IDA:UniProtKB. | | | | | | | | | | GO:0008013; F:beta-catenin binding; IPI:BHF-UCL.::GO:0045296; F:cadherin binding; IPI:BHF-UCL.::GO:0015279; F:store-operated calcium channel activity; IMP:UniProtKB. | | | | | | | | | | GO:0007411; P:axon guidance; TAS:Reactome.::GO:0070509; P:calcium ion import; IDA:BHF-UCL. | 24 | O35119 | 977 | TRPC4_RAT Short transient receptor potential ... | 265 | 0.51 | 37.4 | 21 | 41 | GO:0005887; C:integral to plasma membrane; IDA:RGD. | | | | | | | | | | | | | | | | | | | | GO:0051924; P:regulation of calcium ion transport; IMP:RGD. | 25 | Q9QUQ5 | 974 | TRPC4_MOUSE Short transient receptor potentia... | 265 | 0.51 | 37.4 | 21 | 41 | GO:0005901; C:caveola; IDA:MGI.::GO:0045121; C:membrane raft; IDA:MGI. | | | | | | | | | | GO:0070679; F:inositol 1,4,5 trisphosphate binding; IDA:BHF-UCL.::GO:0015279; F:store-operated calcium channel activity; IMP:MGI. | | | | | | | | | | GO:0014051; P:gamma-aminobutyric acid secretion; IMP:MGI. | 26 | P79100 | 979 | TRPC4_BOVIN Short transient receptor potentia... | 265 | 0.59 | 37 | 21 | 41 | | | | | | | | | | | | | | | | | | | | | | 27 | Q8IZK6 | 566 | MCLN2_HUMAN Mucolipin-2 OS=Homo sapiens (Huma... | 149 | 0.7 | 36.6 | 25 | 46 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005216; F:ion channel activity; IEA:UniProtKB-KW. | | | | | | | | | | | 28 | P19334 | 1275 | TRP_DROME Transient receptor potential protei... | 72 | 0.73 | 37 | 29 | 56 | GO:0016027; C:inaD signaling complex; IPI:UniProtKB.::GO:0016021; C:integral to membrane; NAS:UniProtKB. | | | | | | | | | | GO:0005516; F:calmodulin binding; TAS:FlyBase.::GO:0005218; F:intracellular ligand-gated calcium channel activity; NAS:FlyBase.::GO:0046982; F:protein heterodimerization activity; IPI:UniProtKB.::GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.::GO:0015279; F:store-operated calcium channel activity; NAS:FlyBase. | | | | | | | | | | GO:0019722; P:calcium-mediated signaling; TAS:FlyBase.::GO:0071454; P:cellular response to anoxia; IGI:FlyBase.::GO:0030845; P:inhibition of phospholipase C activity involved in G-protein coupled receptor signaling pathway; IMP:FlyBase.::GO:0008377; P:light-induced release of internally sequestered calcium ion; IDA:FlyBase.::GO:0008355; P:olfactory learning; IMP:UniProtKB.::GO:0008104; P:protein localization; IMP:UniProtKB.::GO:0007608; P:sensory perception of smell; IEA:UniProtKB-KW. | 29 | Q18297 | 1211 | TRPA1_CAEEL Transient receptor potential cati... | 135 | 0.97 | 36.6 | 25 | 42 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005216; F:ion channel activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0000003; P:reproduction; IMP:WormBase.::GO:0050896; P:response to stimulus; IEA:UniProtKB-KW. | 30 | P48995 | 793 | TRPC1_HUMAN Short transient receptor potentia... | 299 | 1.1 | 36.2 | 20 | 39 | GO:0005887; C:integral to plasma membrane; TAS:ProtInc. | | | | | | | | | | GO:0070679; F:inositol 1,4,5 trisphosphate binding; IDA:BHF-UCL.::GO:0044325; F:ion channel binding; IPI:BHF-UCL.::GO:0005515; F:protein binding; IPI:BHF-UCL.::GO:0015279; F:store-operated calcium channel activity; TAS:ProtInc. | | | | | | | | | | GO:0007411; P:axon guidance; TAS:Reactome.::GO:0051480; P:cytosolic calcium ion homeostasis; IDA:BHF-UCL.::GO:0051281; P:positive regulation of release of sequestered calcium ion into cytosol; IDA:BHF-UCL.::GO:0051592; P:response to calcium ion; IDA:BHF-UCL. | 31 | Q8BLA8 | 1125 | TRPA1_MOUSE Transient receptor potential cati... | 243 | 1.2 | 36.2 | 24 | 43 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0032421; C:stereocilium bundle; IDA:MGI. | | | | | | | | | | GO:0005262; F:calcium channel activity; IDA:MGI. | | | | | | | | | | GO:0050968; P:detection of chemical stimulus involved in sensory perception of pain; IDA:MGI.::GO:0050966; P:detection of mechanical stimulus involved in sensory perception of pain; IMP:MGI.::GO:0009409; P:response to cold; IDA:MGI.::GO:0042493; P:response to drug; IDA:MGI.::GO:0042542; P:response to hydrogen peroxide; IMP:MGI.::GO:0048265; P:response to pain; IDA:MGI.::GO:0050955; P:thermoception; IDA:MGI. |