rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | Q8X0X0 | 728 | GSH1_NEUCR Glutamate--cysteine ligase OS=1257... | 700 | 0 | 976 | 70 | 79 | GO:0005737; C:cytoplasm; ISS:RefGenome. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004357; F:glutamate-cysteine ligase activity; ISS:RefGenome. | | | | | | | | | | GO:0006750; P:glutathione biosynthetic process; ISS:RefGenome. | 2 | Q09768 | 669 | GSH1_SCHPO Glutamate--cysteine ligase OS=Schi... | 698 | 0 | 628 | 47 | 62 | GO:0005829; C:cytosol; IDA:PomBase.::GO:0017109; C:glutamate-cysteine ligase complex; ISS:PomBase.::GO:0005634; C:nucleus; IDA:PomBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004357; F:glutamate-cysteine ligase activity; IMP:PomBase. | | | | | | | | | | GO:0071276; P:cellular response to cadmium ion; IMP:PomBase.::GO:0006750; P:glutathione biosynthetic process; IMP:PomBase. | 3 | P97494 | 637 | GSH1_MOUSE Glutamate--cysteine ligase catalyt... | 639 | 0 | 617 | 48 | 67 | GO:0005829; C:cytosol; IDA:MGI.::GO:0017109; C:glutamate-cysteine ligase complex; IDA:MGI. | | | | | | | | | | GO:0043531; F:ADP binding; ISS:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0050662; F:coenzyme binding; ISS:UniProtKB.::GO:0016595; F:glutamate binding; ISS:UniProtKB.::GO:0004357; F:glutamate-cysteine ligase activity; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0046982; F:protein heterodimerization activity; IPI:MGI. | | | | | | | | | | GO:0006916; P:anti-apoptosis; ISS:UniProtKB.::GO:0045454; P:cell redox homeostasis; ISS:UniProtKB.::GO:0006534; P:cysteine metabolic process; ISS:UniProtKB.::GO:0006536; P:glutamate metabolic process; ISS:UniProtKB.::GO:0006750; P:glutathione biosynthetic process; ISS:UniProtKB.::GO:0019852; P:L-ascorbic acid metabolic process; IMP:MGI.::GO:0031397; P:negative regulation of protein ubiquitination; IMP:MGI.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0032436; P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process; IMP:MGI.::GO:0050880; P:regulation of blood vessel size; ISS:UniProtKB.::GO:0051900; P:regulation of mitochondrial depolarization; IGI:MGI.::GO:0046685; P:response to arsenic-containing substance; IMP:MGI.::GO:0009408; P:response to heat; ISS:UniProtKB.::GO:0009725; P:response to hormone stimulus; ISS:UniProtKB.::GO:0006979; P:response to oxidative stress; ISS:UniProtKB.::GO:0009410; P:response to xenobiotic stimulus; IMP:MGI. | 4 | P19468 | 637 | GSH1_RAT Glutamate--cysteine ligase catalytic... | 639 | 0 | 615 | 48 | 67 | GO:0017109; C:glutamate-cysteine ligase complex; IDA:RGD. | | | | | | | | | | GO:0043531; F:ADP binding; ISS:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0050662; F:coenzyme binding; ISS:UniProtKB.::GO:0016595; F:glutamate binding; ISS:UniProtKB.::GO:0004357; F:glutamate-cysteine ligase activity; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0046982; F:protein heterodimerization activity; IDA:RGD. | | | | | | | | | | GO:0006916; P:anti-apoptosis; ISS:UniProtKB.::GO:0045454; P:cell redox homeostasis; ISS:UniProtKB.::GO:0006534; P:cysteine metabolic process; ISS:UniProtKB.::GO:0006536; P:glutamate metabolic process; ISS:UniProtKB.::GO:0006750; P:glutathione biosynthetic process; ISS:UniProtKB.::GO:0043524; P:negative regulation of neuron apoptotic process; IMP:RGD.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0050880; P:regulation of blood vessel size; ISS:UniProtKB.::GO:0009408; P:response to heat; ISS:UniProtKB.::GO:0009725; P:response to hormone stimulus; ISS:UniProtKB.::GO:0051409; P:response to nitrosative stress; IMP:RGD.::GO:0006979; P:response to oxidative stress; ISS:UniProtKB. | 5 | P48506 | 637 | GSH1_HUMAN Glutamate--cysteine ligase catalyt... | 636 | 0 | 609 | 48 | 67 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0043531; F:ADP binding; IDA:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0050662; F:coenzyme binding; IPI:UniProtKB.::GO:0016595; F:glutamate binding; IDA:UniProtKB.::GO:0004357; F:glutamate-cysteine ligase activity; IDA:UniProtKB.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB. | | | | | | | | | | GO:0006916; P:anti-apoptosis; IDA:UniProtKB.::GO:0045454; P:cell redox homeostasis; IDA:UniProtKB.::GO:0006534; P:cysteine metabolic process; IDA:UniProtKB.::GO:0006536; P:glutamate metabolic process; IDA:UniProtKB.::GO:0006750; P:glutathione biosynthetic process; IDA:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0050880; P:regulation of blood vessel size; IMP:UniProtKB.::GO:0009408; P:response to heat; IDA:UniProtKB.::GO:0009725; P:response to hormone stimulus; IDA:UniProtKB.::GO:0006979; P:response to oxidative stress; IDA:UniProtKB.::GO:0006805; P:xenobiotic metabolic process; TAS:Reactome. | 6 | Q9NFN6 | 652 | GSH1_ONCVO Glutamate--cysteine ligase OS=Onch... | 642 | 0 | 555 | 46 | 63 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004357; F:glutamate-cysteine ligase activity; IEA:EC. | | | | | | | | | | GO:0006750; P:glutathione biosynthetic process; IEA:UniProtKB-KW. | 7 | Q54PC2 | 626 | GSH1_DICDI Glutamate--cysteine ligase OS=Dict... | 641 | 0 | 537 | 43 | 64 | GO:0005737; C:cytoplasm; IBA:RefGenome. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004357; F:glutamate-cysteine ligase activity; IMP:UniProtKB. | | | | | | | | | | GO:0006750; P:glutathione biosynthetic process; IMP:UniProtKB.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0007346; P:regulation of mitotic cell cycle; IMP:dictyBase.::GO:0030435; P:sporulation resulting in formation of a cellular spore; IMP:dictyBase. | 8 | Q20117 | 654 | GSH1_CAEEL Glutamate--cysteine ligase OS=Caen... | 642 | 6e-174 | 518 | 44 | 61 | GO:0005737; C:cytoplasm; IBA:RefGenome. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004357; F:glutamate-cysteine ligase activity; IBA:RefGenome.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0006750; P:glutathione biosynthetic process; IMP:WormBase.::GO:0046685; P:response to arsenic-containing substance; IMP:WormBase.::GO:0009408; P:response to heat; IEP:WormBase.::GO:0009635; P:response to herbicide; IEP:WormBase. | 9 | P32477 | 678 | GSH1_YEAST Glutamate--cysteine ligase OS=Sacc... | 695 | 2e-153 | 466 | 41 | 56 | GO:0005737; C:cytoplasm; IBA:RefGenome. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004357; F:glutamate-cysteine ligase activity; IDA:SGD. | | | | | | | | | | GO:0006750; P:glutathione biosynthetic process; IDA:SGD.::GO:0046686; P:response to cadmium ion; IDA:SGD.::GO:0042542; P:response to hydrogen peroxide; IMP:SGD. | 10 | Q9W3K5 | 717 | GSH1_DROME Glutamate--cysteine ligase OS=Dros... | 97 | 3e-24 | 111 | 51 | 72 | GO:0017109; C:glutamate-cysteine ligase complex; IPI:FlyBase.::GO:0005634; C:nucleus; IDA:FlyBase.::GO:0048471; C:perinuclear region of cytoplasm; IDA:FlyBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004357; F:glutamate-cysteine ligase activity; NAS:UniProtKB.::GO:0005515; F:protein binding; IPI:FlyBase. | | | | | | | | | | GO:0006750; P:glutathione biosynthetic process; NAS:UniProtKB.::GO:0006974; P:response to DNA damage stimulus; IMP:FlyBase. | 11 | Q9HF78 | 690 | GSH1_CANAX Glutamate--cysteine ligase OS=Cand... | 554 | 1e-145 | 446 | 44 | 62 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004357; F:glutamate-cysteine ligase activity; IEA:EC. | | | | | | | | | | GO:0006750; P:glutathione biosynthetic process; IEA:UniProtKB-KW. | 12 | C5DPA1 | 313 | YNF8_ZYGRC Vacuolar membrane protein ZYRO0A01... | 67 | 1.4 | 35.4 | 30 | 51 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005774; C:vacuolar membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 13 | A8W3B6 | 1070 | RPOB_CUSEX DNA-directed RNA polymerase subuni... | 89 | 7.7 | 33.5 | 26 | 47 | GO:0009536; C:plastid; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:InterPro.::GO:0003899; F:DNA-directed RNA polymerase activity; IEA:UniProtKB-KW.::GO:0032549; F:ribonucleoside binding; IEA:InterPro. | | | | | | | | | | | 14 | Q99MS7 | 1716 | EH1L1_MOUSE EH domain-binding protein 1-like ... | 65 | 8.8 | 33.5 | 29 | 49 | | | | | | | | | | | | | | | | | | | | | |