rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
61 | Q8HYN0 | 508 | CP17A_PAPCY Steroid 17-alpha-hydroxylase/17,2... | 369 | 1e-16 | 85.9 | 25 | 43 | GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004508; F:steroid 17-alpha-monooxygenase activity; IEA:EC. | | | | | | | | | | GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW. | 62 | Q95078 | 538 | CP18A_DROME Cytochrome P450 18a1 OS=Drosophil... | 175 | 2e-16 | 85.5 | 31 | 52 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro.::GO:0008395; F:steroid hydroxylase activity; IDA:FlyBase. | | | | | | | | | | GO:0046344; P:ecdysteroid catabolic process; IMP:FlyBase.::GO:0007480; P:imaginal disc-derived leg morphogenesis; IMP:FlyBase.::GO:0035210; P:prepupal development; IMP:FlyBase.::GO:0035074; P:pupation; IMP:FlyBase. | 63 | P05179 | 490 | CP2C7_RAT Cytochrome P450 2C7 OS=Rattus norve... | 338 | 2e-16 | 85.1 | 26 | 43 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IDA:RGD. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | GO:0042493; P:response to drug; IEP:RGD.::GO:0045471; P:response to ethanol; IEP:RGD.::GO:0032496; P:response to lipopolysaccharide; IEP:RGD.::GO:0014070; P:response to organic cyclic compound; IEP:RGD.::GO:0010243; P:response to organic nitrogen; IEP:RGD.::GO:0043434; P:response to peptide hormone stimulus; IEP:RGD.::GO:0032526; P:response to retinoic acid; IEP:RGD. | 64 | P56591 | 519 | CP1A1_SHEEP Cytochrome P450 1A1 OS=Ovis aries... | 268 | 2e-16 | 85.5 | 24 | 46 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 65 | P00179 | 487 | CP2C5_RABIT Cytochrome P450 2C5 OS=Oryctolagu... | 365 | 2e-16 | 85.1 | 25 | 43 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 66 | Q55AJ4 | 492 | C516B_DICDI Probable cytochrome P450 516B1 OS... | 252 | 2e-16 | 85.1 | 27 | 44 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 67 | Q8HYM9 | 508 | CP17A_MACMU Steroid 17-alpha-hydroxylase/17,2... | 369 | 3e-16 | 85.1 | 25 | 43 | GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004508; F:steroid 17-alpha-monooxygenase activity; IEA:EC. | | | | | | | | | | | 68 | Q2XVA1 | 508 | CP17A_MACFA Steroid 17-alpha-hydroxylase/17,2... | 369 | 3e-16 | 85.1 | 25 | 43 | GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004508; F:steroid 17-alpha-monooxygenase activity; IEA:EC. | | | | | | | | | | GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW. | 69 | Q05421 | 493 | CP2E1_MOUSE Cytochrome P450 2E1 OS=Mus muscul... | 340 | 3e-16 | 84.7 | 28 | 43 | GO:0005792; C:microsome; IDA:MGI. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; ISS:UniProtKB.::GO:0016709; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen; IEA:EC. | | | | | | | | | | | 70 | P29981 | 511 | CP4C1_BLADI Cytochrome P450 4C1 OS=Blaberus d... | 492 | 4e-16 | 84.3 | 24 | 44 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 71 | P11371 | 487 | CP2C4_RABIT Cytochrome P450 2C4 OS=Oryctolagu... | 365 | 6e-16 | 84 | 24 | 42 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 72 | P70687 | 511 | CP17A_MESAU Steroid 17-alpha-hydroxylase/17,2... | 195 | 6e-16 | 84 | 30 | 49 | GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004508; F:steroid 17-alpha-monooxygenase activity; IEA:EC. | | | | | | | | | | GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW. | 73 | O46515 | 520 | CP11A_HORSE Cholesterol side-chain cleavage e... | 469 | 6e-16 | 84 | 25 | 42 | GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008386; F:cholesterol monooxygenase (side-chain-cleaving) activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | GO:0008203; P:cholesterol metabolic process; IEA:UniProtKB-KW.::GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW. | 74 | Q2LA60 | 492 | CP21A_FELCA Steroid 21-hydroxylase OS=Felis c... | 375 | 6e-16 | 84 | 25 | 43 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004509; F:steroid 21-monooxygenase activity; IEA:EC.::GO:0005496; F:steroid binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW. | 75 | P05182 | 493 | CP2E1_RAT Cytochrome P450 2E1 OS=Rattus norve... | 365 | 7e-16 | 84 | 27 | 42 | GO:0000139; C:Golgi membrane; IDA:RGD.::GO:0031227; C:intrinsic to endoplasmic reticulum membrane; IDA:RGD.::GO:0005792; C:microsome; IDA:RGD.::GO:0005739; C:mitochondrion; IDA:RGD. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0010181; F:FMN binding; IC:RGD.::GO:0020037; F:heme binding; ISS:UniProtKB.::GO:0016709; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen; IEA:EC.::GO:0016712; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; IDA:RGD. | | | | | | | | | | GO:0042493; P:response to drug; IEP:RGD.::GO:0045471; P:response to ethanol; IEP:RGD.::GO:0010243; P:response to organic nitrogen; IEP:RGD.::GO:0010193; P:response to ozone; IEP:RGD.::GO:0006641; P:triglyceride metabolic process; IMP:RGD.::GO:0006805; P:xenobiotic metabolic process; IMP:RGD. | 76 | P20814 | 490 | CP2CD_RAT Cytochrome P450 2C13, male-specific... | 352 | 8e-16 | 83.6 | 26 | 43 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 77 | P15540 | 492 | CP21A_PIG Steroid 21-hydroxylase OS=Sus scrof... | 371 | 8e-16 | 83.6 | 26 | 42 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004509; F:steroid 21-monooxygenase activity; IEA:EC.::GO:0005496; F:steroid binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW. | 78 | Q9GLD2 | 508 | CP17A_PAPHU Steroid 17-alpha-hydroxylase/17,2... | 369 | 8e-16 | 83.6 | 25 | 43 | GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004508; F:steroid 17-alpha-monooxygenase activity; IEA:EC. | | | | | | | | | | GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW. | 79 | Q2LCM1 | 492 | CP21A_CANLU Steroid 21-hydroxylase OS=Canis l... | 445 | 9e-16 | 83.2 | 23 | 41 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004509; F:steroid 21-monooxygenase activity; IEA:EC.::GO:0005496; F:steroid binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW. | 80 | Q8WNW0 | 492 | CP21A_CANFA Steroid 21-hydroxylase OS=Canis f... | 445 | 9e-16 | 83.2 | 23 | 41 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004509; F:steroid 21-monooxygenase activity; IEA:EC.::GO:0005496; F:steroid binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW. | 81 | Q2LA59 | 492 | CP21A_LYNLY Steroid 21-hydroxylase OS=Lynx ly... | 375 | 0.000000000000001 | 83.2 | 24 | 43 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004509; F:steroid 21-monooxygenase activity; IEA:EC.::GO:0005496; F:steroid binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW. | 82 | P56657 | 491 | CP240_MOUSE Cytochrome P450 2C40 OS=Mus muscu... | 362 | 0.000000000000001 | 83.2 | 26 | 41 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 83 | Q27520 | 519 | C13A1_CAEEL Putative cytochrome P450 CYP13A1 ... | 452 | 0.000000000000001 | 82.8 | 24 | 42 | | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 84 | P05181 | 493 | CP2E1_HUMAN Cytochrome P450 2E1 OS=Homo sapie... | 323 | 0.000000000000001 | 82.8 | 26 | 43 | GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0005792; C:microsome; IDA:BHF-UCL. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0019899; F:enzyme binding; IPI:BHF-UCL.::GO:0020037; F:heme binding; IDA:UniProtKB.::GO:0016709; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen; TAS:UniProtKB.::GO:0016712; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; IEA:InterPro.::GO:0019825; F:oxygen binding; TAS:ProtInc. | | | | | | | | | | GO:0017144; P:drug metabolic process; IDA:BHF-UCL.::GO:0046483; P:heterocycle metabolic process; IDA:BHF-UCL.::GO:0016098; P:monoterpenoid metabolic process; IDA:BHF-UCL.::GO:0044281; P:small molecule metabolic process; TAS:Reactome.::GO:0008202; P:steroid metabolic process; IMP:BHF-UCL.::GO:0006805; P:xenobiotic metabolic process; TAS:Reactome. | 85 | P20853 | 494 | CP2A7_HUMAN Cytochrome P450 2A7 OS=Homo sapie... | 509 | 0.000000000000001 | 82.8 | 24 | 40 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0019825; F:oxygen binding; TAS:ProtInc. | | | | | | | | | | | 86 | Q9V419 | 505 | C28A5_DROME Probable cytochrome P450 28a5 OS=... | 381 | 0.000000000000002 | 82.8 | 23 | 45 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 87 | Q5KQT7 | 517 | CP1A1_FELCA Cytochrome P450 1A1 OS=Felis catu... | 249 | 0.000000000000002 | 82.8 | 22 | 48 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 88 | P00184 | 524 | CP1A1_MOUSE Cytochrome P450 1A1 OS=Mus muscul... | 186 | 0.000000000000002 | 82 | 28 | 51 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IDA:MGI. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | GO:0009308; P:amine metabolic process; IMP:MGI.::GO:0050665; P:hydrogen peroxide biosynthetic process; IMP:MGI. | 89 | P04798 | 512 | CP1A1_HUMAN Cytochrome P450 1A1 OS=Homo sapie... | 257 | 0.000000000000002 | 82 | 25 | 46 | GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0005792; C:microsome; IDA:BHF-UCL. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0019825; F:oxygen binding; TAS:ProtInc.::GO:0070576; F:vitamin D 24-hydroxylase activity; IDA:BHF-UCL. | | | | | | | | | | GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.::GO:0017144; P:drug metabolic process; IDA:BHF-UCL.::GO:0042359; P:vitamin D metabolic process; IC:BHF-UCL.::GO:0006805; P:xenobiotic metabolic process; TAS:Reactome. | 90 | Q9QZ82 | 526 | CP11A_MOUSE Cholesterol side-chain cleavage e... | 513 | 0.000000000000002 | 82 | 24 | 39 | | | | | | | | | | | GO:0008386; F:cholesterol monooxygenase (side-chain-cleaving) activity; IDA:MGI.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | GO:0008203; P:cholesterol metabolic process; IEA:UniProtKB-KW. | 91 | P33616 | 512 | CP1A1_MACFA Cytochrome P450 1A1 OS=Macaca fas... | 188 | 0.000000000000003 | 81.6 | 27 | 51 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | |