rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
271 | Q54E35 | 570 | GACEE_DICDI Rho GTPase-activating protein gac... | 69 | 0.0003 | 48.5 | 39 | 52 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 272 | Q9JKS6 | 5085 | PCLO_RAT Protein piccolo OS=Rattus norvegicus... | 49 | 0.89 | 37.4 | 31 | 61 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0045202; C:synapse; IDA:UniProtKB. | | | | | | | | | | GO:0005509; F:calcium ion binding; IDA:UniProtKB.::GO:0005544; F:calcium-dependent phospholipid binding; IDA:UniProtKB.::GO:0005522; F:profilin binding; ISS:UniProtKB. | | | | | | | | | | GO:0007010; P:cytoskeleton organization; ISS:UniProtKB.::GO:0016080; P:synaptic vesicle targeting; NAS:UniProtKB. | 273 | Q86KB1 | 617 | ADCB_DICDI Arrestin domain-containing protein... | 115 | 0.000000004 | 64.3 | 36 | 52 | | | | | | | | | | | | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 274 | Q9QYX7 | 5038 | PCLO_MOUSE Protein piccolo OS=Mus musculus (M... | 49 | 0.9 | 37.4 | 31 | 61 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0045202; C:synapse; IDA:UniProtKB. | | | | | | | | | | GO:0005509; F:calcium ion binding; ISS:UniProtKB.::GO:0005544; F:calcium-dependent phospholipid binding; ISS:UniProtKB.::GO:0005522; F:profilin binding; IDA:UniProtKB. | | | | | | | | | | GO:0019933; P:cAMP-mediated signaling; IDA:MGI.::GO:0007010; P:cytoskeleton organization; IDA:MGI.::GO:0030073; P:insulin secretion; IDA:MGI.::GO:0017157; P:regulation of exocytosis; IDA:MGI.::GO:0016080; P:synaptic vesicle targeting; NAS:UniProtKB. | 275 | Q9Z1N9 | 1602 | UN13B_MOUSE Protein unc-13 homolog B OS=Mus m... | 80 | 0.1 | 40.4 | 31 | 45 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0045202; C:synapse; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0001566; F:non-kinase phorbol ester receptor activity; TAS:MGI. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0048172; P:regulation of short-term neuronal synaptic plasticity; IMP:MGI.::GO:0035249; P:synaptic transmission, glutamatergic; IMP:MGI.::GO:0016081; P:synaptic vesicle docking involved in exocytosis; IGI:MGI.::GO:0016082; P:synaptic vesicle priming; IMP:MGI. | 276 | Q9UTB5 | 516 | PSD2_SCHPO Phosphatidylserine decarboxylase p... | 74 | 0.003 | 45.1 | 41 | 58 | GO:0005743; C:mitochondrial inner membrane; ISS:PomBase.::GO:0005635; C:nuclear envelope; IDA:PomBase. | | | | | | | | | | GO:0004609; F:phosphatidylserine decarboxylase activity; IEA:EC. | | | | | | | | | | GO:0006656; P:phosphatidylcholine biosynthetic process; ISS:PomBase. | 277 | Q9UPW8 | 1703 | UN13A_HUMAN Protein unc-13 homolog A OS=Homo ... | 80 | 0.23 | 39.3 | 30 | 44 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0042734; C:presynaptic membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 278 | P27715 | 2155 | UNC13_CAEEL Phorbol ester/diacylglycerol-bind... | 90 | 0.12 | 40.4 | 31 | 44 | GO:0048786; C:presynaptic active zone; IDA:WormBase. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007411; P:axon guidance; IMP:WormBase.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0040010; P:positive regulation of growth rate; IMP:WormBase.::GO:0046662; P:regulation of oviposition; IMP:WormBase.::GO:0043051; P:regulation of pharyngeal pumping; IMP:WormBase. | 279 | Q4KUS2 | 1712 | UN13A_MOUSE Protein unc-13 homolog A OS=Mus m... | 80 | 0.26 | 39.3 | 30 | 44 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0042734; C:presynaptic membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0019992; F:diacylglycerol binding; IDA:MGI.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0050435; P:beta-amyloid metabolic process; IMP:MGI.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0048172; P:regulation of short-term neuronal synaptic plasticity; IMP:MGI.::GO:0035249; P:synaptic transmission, glutamatergic; IMP:MGI.::GO:0016081; P:synaptic vesicle docking involved in exocytosis; IGI:MGI.::GO:0016188; P:synaptic vesicle maturation; IMP:MGI. | 280 | Q62769 | 1622 | UN13B_RAT Protein unc-13 homolog B OS=Rattus ... | 80 | 0.1 | 40.4 | 31 | 45 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0045202; C:synapse; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006887; P:exocytosis; IEA:UniProtKB-KW.::GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 281 | Q6PFQ7 | 802 | RASL2_MOUSE Ras GTPase-activating protein 4 O... | 49 | 0.19 | 39.7 | 39 | 61 | GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0031235; C:intrinsic to internal side of plasma membrane; IBA:RefGenome. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005099; F:Ras GTPase activator activity; IBA:RefGenome. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0046580; P:negative regulation of Ras protein signal transduction; IBA:RefGenome. | 282 | Q8L7A4 | 385 | AGD11_ARATH Probable ADP-ribosylation factor ... | 96 | 0.0000009 | 56.2 | 34 | 56 | | | | | | | | | | | GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro. | 283 | Q5RJH2 | 878 | MCTP2_MOUSE Multiple C2 and transmembrane dom... | 75 | 0.68 | 37.7 | 31 | 44 | GO:0016021; C:integral to membrane; ISS:HGNC.::GO:0005624; C:membrane fraction; ISS:HGNC. | | | | | | | | | | GO:0005509; F:calcium ion binding; ISS:HGNC. | | | | | | | | | | | 284 | O14795 | 1591 | UN13B_HUMAN Protein unc-13 homolog B OS=Homo ... | 80 | 0.68 | 37.7 | 30 | 44 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005794; C:Golgi apparatus; TAS:ProtInc.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0045202; C:synapse; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004872; F:receptor activity; TAS:ProtInc.::GO:0004871; F:signal transducer activity; TAS:ProtInc. | | | | | | | | | | GO:0007588; P:excretion; TAS:ProtInc.::GO:0006917; P:induction of apoptosis; TAS:ProtInc.::GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 285 | Q7L804 | 512 | RFIP2_HUMAN Rab11 family-interacting protein ... | 147 | 0.00000004 | 60.8 | 32 | 52 | GO:0030659; C:cytoplasmic vesicle membrane; TAS:Reactome.::GO:0005634; C:nucleus; IDA:HPA.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0055038; C:recycling endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.::GO:0019901; F:protein kinase binding; IPI:UniProtKB. | | | | | | | | | | GO:0030010; P:establishment of cell polarity; IMP:UniProtKB.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0055085; P:transmembrane transport; TAS:Reactome.::GO:0006833; P:water transport; TAS:Reactome. | 286 | Q55A55 | 986 | Y9848_DICDI Probable serine/threonine-protein... | 134 | 0.00000005 | 60.8 | 37 | 50 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 287 | Q6DN14 | 999 | MCTP1_HUMAN Multiple C2 and transmembrane dom... | 73 | 0.85 | 37.4 | 32 | 44 | GO:0016021; C:integral to membrane; IDA:HGNC.::GO:0005624; C:membrane fraction; ISS:HGNC. | | | | | | | | | | GO:0005509; F:calcium ion binding; IDA:HGNC. | | | | | | | | | | GO:0019722; P:calcium-mediated signaling; NAS:HGNC. | 288 | Q6DN12 | 878 | MCTP2_HUMAN Multiple C2 and transmembrane dom... | 75 | 3 | 35.4 | 29 | 44 | GO:0016021; C:integral to membrane; IDA:HGNC.::GO:0005624; C:membrane fraction; IDA:HGNC. | | | | | | | | | | GO:0005509; F:calcium ion binding; IDA:HGNC. | | | | | | | | | | GO:0019722; P:calcium-mediated signaling; NAS:HGNC. | 289 | Q9ZVT9 | 1020 | C2GR1_ARATH C2 and GRAM domain-containing pro... | 60 | 0.023 | 42.4 | 40 | 58 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | | | | | | | | | | | | 290 | Q62768 | 1735 | UN13A_RAT Protein unc-13 homolog A OS=Rattus ... | 80 | 0.12 | 40.4 | 30 | 45 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0060076; C:excitatory synapse; IDA:BHF-UCL.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0042734; C:presynaptic membrane; IDA:RGD.::GO:0043234; C:protein complex; IDA:RGD.::GO:0019717; C:synaptosome; IDA:RGD. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0019904; F:protein domain specific binding; IDA:RGD.::GO:0046982; F:protein heterodimerization activity; IDA:RGD.::GO:0042803; F:protein homodimerization activity; IDA:RGD.::GO:0000149; F:SNARE binding; IDA:RGD. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0060291; P:long-term synaptic potentiation; IMP:RGD.::GO:0016082; P:synaptic vesicle priming; IDA:RGD. | 291 | P41885 | 1106 | RBF1_CAEEL Rabphilin-1 OS=Caenorhabditis eleg... | 77 | 0.14 | 40 | 39 | 49 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0016020; C:membrane; IEA:InterPro.::GO:0008021; C:synaptic vesicle; IDA:WormBase. | | | | | | | | | | GO:0017137; F:Rab GTPase binding; IEA:InterPro.::GO:0005215; F:transporter activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006887; P:exocytosis; IEA:UniProtKB-KW.::GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0040017; P:positive regulation of locomotion; IMP:WormBase. | 292 | Q8NB66 | 2214 | UN13C_HUMAN Protein unc-13 homolog C OS=Homo ... | 51 | 0.038 | 42 | 39 | 53 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.::GO:0042734; C:presynaptic membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006887; P:exocytosis; IEA:UniProtKB-KW.::GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 293 | Q62770 | 2204 | UN13C_RAT Protein unc-13 homolog C OS=Rattus ... | 80 | 0.036 | 42 | 31 | 45 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IDA:RGD.::GO:0042734; C:presynaptic membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006887; P:exocytosis; IEA:UniProtKB-KW.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0046928; P:regulation of neurotransmitter secretion; TAS:RGD. | 294 | Q8K0T7 | 2210 | UN13C_MOUSE Protein unc-13 homolog C OS=Mus m... | 51 | 0.032 | 42.4 | 39 | 53 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.::GO:0042734; C:presynaptic membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0001566; F:non-kinase phorbol ester receptor activity; TAS:MGI. | | | | | | | | | | GO:0006887; P:exocytosis; IEA:UniProtKB-KW.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0007268; P:synaptic transmission; IMP:MGI. | 295 | Q5DTI8 | 891 | ESYT3_MOUSE Extended synaptotagmin-3 OS=Mus m... | 202 | 0.000001 | 56.2 | 27 | 43 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 296 | P46935 | 887 | NEDD4_MOUSE E3 ubiquitin-protein ligase NEDD4... | 110 | 0.01 | 43.5 | 27 | 52 | GO:0005829; C:cytosol; IDA:MGI.::GO:0005624; C:membrane fraction; IDA:MGI.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0000151; C:ubiquitin ligase complex; IPI:MGI. | | | | | | | | | | GO:0050815; F:phosphoserine binding; IDA:BHF-UCL.::GO:0050816; F:phosphothreonine binding; IDA:BHF-UCL.::GO:0070064; F:proline-rich region binding; IPI:MGI.::GO:0019871; F:sodium channel inhibitor activity; IDA:MGI.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:MGI. | | | | | | | | | | GO:0010766; P:negative regulation of sodium ion transport; IDA:MGI.::GO:0030948; P:negative regulation of vascular endothelial growth factor receptor signaling pathway; IDA:UniProtKB.::GO:0045732; P:positive regulation of protein catabolic process; IDA:MGI.::GO:0070534; P:protein K63-linked ubiquitination; ISS:UniProtKB.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.::GO:0048814; P:regulation of dendrite morphogenesis; IMP:UniProtKB. | 297 | Q62940 | 887 | NEDD4_RAT E3 ubiquitin-protein ligase NEDD4 O... | 110 | 0.009 | 43.9 | 27 | 52 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0045121; C:membrane raft; IDA:RGD.::GO:0005902; C:microvillus; IDA:RGD.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008022; F:protein C-terminus binding; IDA:RGD.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB. | | | | | | | | | | GO:0006955; P:immune response; IEP:RGD.::GO:0030948; P:negative regulation of vascular endothelial growth factor receptor signaling pathway; ISS:UniProtKB.::GO:0070534; P:protein K63-linked ubiquitination; IDA:UniProtKB.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.::GO:0048814; P:regulation of dendrite morphogenesis; IDA:UniProtKB. | 298 | Q8LFN9 | 336 | AGD13_ARATH Probable ADP-ribosylation factor ... | 103 | 0.0002 | 48.1 | 33 | 50 | | | | | | | | | | | GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0009555; P:pollen development; IMP:TAIR.::GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro. | 299 | O14333 | 437 | PSD1_SCHPO Phosphatidylserine decarboxylase p... | 65 | 0.002 | 45.4 | 43 | 58 | GO:0005743; C:mitochondrial inner membrane; ISS:PomBase. | | | | | | | | | | GO:0004609; F:phosphatidylserine decarboxylase activity; IEA:EC. | | | | | | | | | | GO:0006656; P:phosphatidylcholine biosynthetic process; ISS:PomBase. | 300 | P41823 | 428 | SY65_APLCA Synaptotagmin-1 OS=Aplysia califor... | 132 | 0.004 | 44.7 | 30 | 48 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0030285; C:integral to synaptic vesicle membrane; IDA:UniProtKB. | | | | | | | | | | GO:0005509; F:calcium ion binding; IDA:UniProtKB.::GO:0000149; F:SNARE binding; IDA:UniProtKB.::GO:0005215; F:transporter activity; IEA:InterPro. | | | | | | | | | | GO:0045955; P:negative regulation of calcium ion-dependent exocytosis; IDA:UniProtKB.::GO:0016079; P:synaptic vesicle exocytosis; IDA:UniProtKB. | 301 | Q93XX4 | 751 | C2D61_ARATH C2 domain-containing protein At1g... | 88 | 0.000008 | 53.5 | 33 | 51 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IDA:TAIR.::GO:0005773; C:vacuole; IDA:TAIR. | | | | | | | | | | | | | | | | | | | | |