rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
931 | Q1LX51 | 532 | WEE2_DANRE Wee1-like protein kinase 2 OS=Dani... | 85 | 0.66 | 34.3 | 31 | 51 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.::GO:0004674; F:protein serine/threonine kinase activity; IEA:InterPro. | | | | | | | | | | GO:0007126; P:meiosis; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:InterPro. | 932 | Q08CW1 | 697 | TLK2_XENTR Serine/threonine-protein kinase to... | 83 | 0.66 | 34.3 | 27 | 42 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 933 | Q8FUI4 | 520 | PKN2_COREF Serine/threonine-protein kinases d... | 67 | 0.67 | 34.3 | 34 | 49 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 934 | Q552C1 | 1555 | Y9957_DICDI Probable serine/threonine-protein... | 97 | 0.68 | 34.3 | 25 | 45 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 935 | O54874 | 1732 | MRCKA_RAT Serine/threonine-protein kinase MRC... | 80 | 0.71 | 34.3 | 31 | 49 | GO:0042641; C:actomyosin; IDA:UniProtKB.::GO:0031252; C:cell leading edge; IDA:UniProtKB.::GO:0005911; C:cell-cell junction; IDA:UniProtKB.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0042802; F:identical protein binding; IPI:UniProtKB.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.::GO:0005083; F:small GTPase regulator activity; IEA:InterPro. | | | | | | | | | | GO:0031532; P:actin cytoskeleton reorganization; IDA:UniProtKB.::GO:0031032; P:actomyosin structure organization; IMP:UniProtKB.::GO:0016477; P:cell migration; IMP:UniProtKB.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0051056; P:regulation of small GTPase mediated signal transduction; IDA:UniProtKB. | 936 | Q09898 | 607 | SID2_SCHPO Serine/threonine-protein kinase si... | 111 | 0.71 | 34.3 | 24 | 41 | GO:0005829; C:cytosol; IDA:PomBase.::GO:0031097; C:medial cortex; IDA:PomBase.::GO:0005634; C:nucleus; IEA:UniProtKB-KW.::GO:0034973; C:Sid2-Mob1 complex; IPI:PomBase.::GO:0005816; C:spindle pole body; IDA:PomBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; TAS:PomBase. | | | | | | | | | | GO:0061167; P:maintenance of endoplasmic reticulum location involved in endoplasmic reticulum polarization at cell division site; IMP:PomBase.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0031028; P:septation initiation signaling cascade; IMP:PomBase. | 937 | P00541 | 533 | FPS_AVISP Tyrosine-protein kinase transformin... | 81 | 0.71 | 34.3 | 27 | 46 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | GO:0016032; P:viral reproduction; IEA:InterPro. | 938 | P28327 | 561 | RK_BOVIN Rhodopsin kinase OS=Bos taurus (Bovi... | 94 | 0.72 | 34.3 | 27 | 39 | GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004703; F:G-protein coupled receptor kinase activity; IEA:InterPro.::GO:0050254; F:rhodopsin kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0022400; P:regulation of rhodopsin mediated signaling pathway; ISS:UniProtKB.::GO:0007165; P:signal transduction; IEA:InterPro.::GO:0038032; P:termination of G-protein coupled receptor signaling pathway; IEA:InterPro.::GO:0007601; P:visual perception; IEA:UniProtKB-KW. | 939 | Q99J82 | 452 | ILK_RAT Integrin-linked protein kinase OS=Rat... | 79 | 0.73 | 33.9 | 24 | 48 | GO:0005911; C:cell-cell junction; IDA:RGD.::GO:0043034; C:costamere; IDA:RGD.::GO:0043198; C:dendritic shaft; IDA:RGD.::GO:0005925; C:focal adhesion; IDA:MGI.::GO:0043025; C:neuronal cell body; IDA:RGD.::GO:0043234; C:protein complex; IDA:RGD.::GO:0043195; C:terminal button; IDA:RGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005178; F:integrin binding; IPI:RGD.::GO:0004674; F:protein serine/threonine kinase activity; IDA:RGD.::GO:0017124; F:SH3 domain binding; IDA:RGD.::GO:0004871; F:signal transducer activity; IDA:RGD. | | | | | | | | | | GO:0007569; P:cell aging; IMP:RGD.::GO:0007050; P:cell cycle arrest; IMP:RGD.::GO:0043206; P:fibril organization; IMP:RGD.::GO:0007229; P:integrin-mediated signaling pathway; IMP:RGD.::GO:0032288; P:myelin assembly; IMP:RGD.::GO:0010667; P:negative regulation of cardiac muscle cell apoptotic process; IMP:RGD.::GO:0043524; P:negative regulation of neuron apoptotic process; IMP:RGD.::GO:0006469; P:negative regulation of protein kinase activity; IMP:RGD.::GO:0014912; P:negative regulation of smooth muscle cell migration; IMP:RGD.::GO:0048662; P:negative regulation of smooth muscle cell proliferation; IMP:RGD.::GO:0048812; P:neuron projection morphogenesis; IMP:RGD.::GO:0018105; P:peptidyl-serine phosphorylation; IMP:RGD.::GO:0045773; P:positive regulation of axon extension; IMP:RGD.::GO:0030335; P:positive regulation of cell migration; IMP:RGD.::GO:0008284; P:positive regulation of cell proliferation; IMP:RGD.::GO:0001954; P:positive regulation of cell-matrix adhesion; IMP:RGD.::GO:0050775; P:positive regulation of dendrite morphogenesis; IMP:RGD.::GO:0043406; P:positive regulation of MAP kinase activity; IMP:RGD.::GO:0043410; P:positive regulation of MAPK cascade; IMP:RGD.::GO:0045663; P:positive regulation of myoblast differentiation; IMP:RGD.::GO:0051897; P:positive regulation of protein kinase B signaling cascade; IMP:RGD.::GO:0051291; P:protein heterooligomerization; IDA:RGD.::GO:0032956; P:regulation of actin cytoskeleton organization; IMP:RGD.::GO:0034446; P:substrate adhesion-dependent cell spreading; IMP:RGD. | 940 | O55222 | 452 | ILK_MOUSE Integrin-linked protein kinase OS=M... | 79 | 0.73 | 33.9 | 24 | 48 | GO:0005925; C:focal adhesion; IDA:MGI. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0001658; P:branching involved in ureteric bud morphogenesis; IDA:MGI.::GO:0045197; P:establishment or maintenance of epithelial cell apical/basal polarity; IMP:MGI.::GO:0030513; P:positive regulation of BMP signaling pathway; IMP:BHF-UCL.::GO:0008284; P:positive regulation of cell proliferation; IMP:MGI.::GO:0045669; P:positive regulation of osteoblast differentiation; IMP:BHF-UCL. | 941 | Q3SWY2 | 452 | ILK_BOVIN Integrin-linked protein kinase OS=B... | 79 | 0.73 | 33.9 | 24 | 48 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009966; P:regulation of signal transduction; IEA:InterPro. | 942 | Q8VDG6 | 1002 | M3KL4_MOUSE Mitogen-activated protein kinase ... | 104 | 0.73 | 34.3 | 29 | 44 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004709; F:MAP kinase kinase kinase activity; IEA:EC.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro. | | | | | | | | | | | 943 | Q8BM85 | 762 | TBCK_MOUSE TBC domain-containing protein kina... | 141 | 0.73 | 34.3 | 25 | 39 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005097; F:Rab GTPase activator activity; IEA:InterPro.::GO:0016772; F:transferase activity, transferring phosphorus-containing groups; IEA:InterPro. | | | | | | | | | | | 944 | P09769 | 529 | FGR_HUMAN Tyrosine-protein kinase Fgr OS=Homo... | 84 | 0.73 | 33.9 | 29 | 45 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.::GO:0005758; C:mitochondrial intermembrane space; IEA:UniProtKB-SubCell.::GO:0032587; C:ruffle membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0034988; F:Fc-gamma receptor I complex binding; IDA:UniProtKB.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IDA:UniProtKB.::GO:0001784; F:phosphotyrosine binding; ISS:UniProtKB.::GO:0019901; F:protein kinase binding; ISS:UniProtKB. | | | | | | | | | | GO:0007596; P:blood coagulation; TAS:Reactome.::GO:0050830; P:defense response to Gram-positive bacterium; ISS:UniProtKB.::GO:0002768; P:immune response-regulating cell surface receptor signaling pathway; TAS:UniProtKB.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW.::GO:0007229; P:integrin-mediated signaling pathway; IMP:UniProtKB.::GO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:UniProtKB.::GO:0030335; P:positive regulation of cell migration; ISS:UniProtKB.::GO:0050715; P:positive regulation of cytokine secretion; ISS:UniProtKB.::GO:0043306; P:positive regulation of mast cell degranulation; ISS:UniProtKB.::GO:0043552; P:positive regulation of phosphatidylinositol 3-kinase activity; IMP:UniProtKB.::GO:0014068; P:positive regulation of phosphatidylinositol 3-kinase cascade; IMP:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:0008360; P:regulation of cell shape; ISS:UniProtKB.::GO:0045088; P:regulation of innate immune response; ISS:UniProtKB.::GO:0050764; P:regulation of phagocytosis; ISS:UniProtKB.::GO:0045859; P:regulation of protein kinase activity; ISS:UniProtKB.::GO:0009615; P:response to virus; TAS:ProtInc. | 945 | Q9QZ05 | 1648 | E2AK4_MOUSE Eukaryotic translation initiation... | 99 | 0.74 | 34.3 | 26 | 43 | GO:0022626; C:cytosolic ribosome; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004694; F:eukaryotic translation initiation factor 2alpha kinase activity; IDA:UniProtKB.::GO:0042803; F:protein homodimerization activity; IEA:InterPro.::GO:0000049; F:tRNA binding; IEA:InterPro. | | | | | | | | | | GO:0009267; P:cellular response to starvation; IDA:MGI.::GO:0030968; P:endoplasmic reticulum unfolded protein response; IMP:MGI.::GO:0017148; P:negative regulation of translation; IGI:MGI.::GO:0043558; P:regulation of translational initiation in response to stress; IDA:MGI. | 946 | O14408 | 382 | KCC1_METAN Calcium/calmodulin-dependent prote... | 93 | 0.74 | 33.9 | 27 | 42 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; IEA:EC. | | | | | | | | | | | 947 | Q9R117 | 1180 | TYK2_MOUSE Non-receptor tyrosine-protein kina... | 101 | 0.75 | 34.3 | 26 | 43 | GO:0005856; C:cytoskeleton; IEA:InterPro.::GO:0016020; C:membrane; IEA:InterPro. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | GO:0007243; P:intracellular protein kinase cascade; IEA:InterPro. | 948 | Q5Z6X0 | 514 | CIPKP_ORYSJ CBL-interacting protein kinase 25... | 92 | 0.75 | 33.9 | 23 | 39 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 949 | Q02763 | 1124 | TIE2_HUMAN Angiopoietin-1 receptor OS=Homo sa... | 80 | 0.75 | 34.3 | 26 | 49 | GO:0016324; C:apical plasma membrane; IDA:UniProtKB.::GO:0009925; C:basal plasma membrane; IDA:UniProtKB.::GO:0009986; C:cell surface; IDA:UniProtKB.::GO:0005911; C:cell-cell junction; IDA:UniProtKB.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.::GO:0005887; C:integral to plasma membrane; IDA:UniProtKB.::GO:0045121; C:membrane raft; IDA:UniProtKB.::GO:0005902; C:microvillus; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004714; F:transmembrane receptor protein tyrosine kinase activity; TAS:ProtInc. | | | | | | | | | | GO:0007596; P:blood coagulation; TAS:Reactome.::GO:0007267; P:cell-cell signaling; TAS:ProtInc.::GO:0060216; P:definitive hemopoiesis; TAS:UniProtKB.::GO:0001935; P:endothelial cell proliferation; ISS:UniProtKB.::GO:0072012; P:glomerulus vasculature development; ISS:UniProtKB.::GO:0060347; P:heart trabecula formation; ISS:UniProtKB.::GO:0050900; P:leukocyte migration; TAS:Reactome.::GO:0016525; P:negative regulation of angiogenesis; IMP:UniProtKB.::GO:2000352; P:negative regulation of endothelial cell apoptotic process; ISS:UniProtKB.::GO:0050728; P:negative regulation of inflammatory response; TAS:UniProtKB.::GO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:UniProtKB.::GO:2000251; P:positive regulation of actin cytoskeleton reorganization; IMP:UniProtKB.::GO:0045766; P:positive regulation of angiogenesis; IDA:UniProtKB.::GO:0010595; P:positive regulation of endothelial cell migration; IDA:UniProtKB.::GO:0001938; P:positive regulation of endothelial cell proliferation; TAS:UniProtKB.::GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; IDA:UniProtKB.::GO:0051894; P:positive regulation of focal adhesion assembly; IMP:UniProtKB.::GO:0043552; P:positive regulation of phosphatidylinositol 3-kinase activity; IMP:UniProtKB.::GO:0014068; P:positive regulation of phosphatidylinositol 3-kinase cascade; IMP:UniProtKB.::GO:0051897; P:positive regulation of protein kinase B signaling cascade; IDA:UniProtKB.::GO:0001934; P:positive regulation of protein phosphorylation; IDA:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:0051259; P:protein oligomerization; IDA:UniProtKB.::GO:0032878; P:regulation of establishment or maintenance of cell polarity; IMP:UniProtKB.::GO:0043114; P:regulation of vascular permeability; TAS:UniProtKB.::GO:0002040; P:sprouting angiogenesis; IMP:UniProtKB.::GO:0034446; P:substrate adhesion-dependent cell spreading; IMP:UniProtKB.::GO:0048014; P:Tie receptor signaling pathway; IDA:UniProtKB. | 950 | Q0D598 | 704 | WNK1_ORYSJ Probable serine/threonine-protein ... | 93 | 0.75 | 34.3 | 29 | 46 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 951 | Q8L4H0 | 500 | WEE1_ARATH Wee1-like protein kinase OS=Arabid... | 78 | 0.75 | 33.9 | 32 | 49 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.::GO:0005515; F:protein binding; IPI:TAIR.::GO:0004674; F:protein serine/threonine kinase activity; IEA:InterPro. | | | | | | | | | | GO:0007050; P:cell cycle arrest; IEP:TAIR.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0000076; P:DNA replication checkpoint; IEP:TAIR.::GO:0007067; P:mitosis; IEA:UniProtKB-KW. | 952 | Q13882 | 451 | PTK6_HUMAN Protein-tyrosine kinase 6 OS=Homo ... | 80 | 0.78 | 33.9 | 30 | 48 | GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0005886; C:plasma membrane; IDA:HPA.::GO:0001726; C:ruffle; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0016477; P:cell migration; IDA:UniProtKB.::GO:0071300; P:cellular response to retinoic acid; IMP:BHF-UCL.::GO:0061099; P:negative regulation of protein tyrosine kinase activity; IDA:UniProtKB.::GO:0010976; P:positive regulation of neuron projection development; IMP:BHF-UCL.::GO:0046777; P:protein autophosphorylation; IMP:UniProtKB.::GO:0042503; P:tyrosine phosphorylation of Stat3 protein; IDA:UniProtKB.::GO:0042506; P:tyrosine phosphorylation of Stat5 protein; IDA:UniProtKB. | 953 | A2YMV6 | 704 | WNK1_ORYSI Probable serine/threonine-protein ... | 93 | 0.78 | 33.9 | 29 | 46 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 954 | Q13418 | 452 | ILK_HUMAN Integrin-linked protein kinase OS=H... | 79 | 0.78 | 33.9 | 24 | 48 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; NAS:UniProtKB.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB. | | | | | | | | | | GO:0034329; P:cell junction assembly; TAS:Reactome.::GO:0008283; P:cell proliferation; NAS:UniProtKB.::GO:0007160; P:cell-matrix adhesion; NAS:UniProtKB.::GO:0007229; P:integrin-mediated signaling pathway; NAS:UniProtKB.::GO:0090263; P:positive regulation of canonical Wnt receptor signaling pathway; IMP:UniProtKB.::GO:0042327; P:positive regulation of phosphorylation; IMP:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IMP:UniProtKB.::GO:0034446; P:substrate adhesion-dependent cell spreading; IMP:UniProtKB. | 955 | P0CY25 | 589 | STE7_CANAX Serine/threonine-protein kinase ST... | 39 | 0.78 | 33.9 | 46 | 56 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 956 | C4YLK8 | 589 | STE7_CANAW Serine/threonine-protein kinase ST... | 39 | 0.78 | 33.9 | 46 | 56 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 957 | Q8MY85 | 887 | FGFR2_DUGJA Fibroblast growth factor receptor... | 70 | 0.79 | 33.9 | 29 | 49 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004714; F:transmembrane receptor protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | | 958 | Q5A6T5 | 589 | STE7_CANAL Serine/threonine-protein kinase ST... | 39 | 0.8 | 33.9 | 46 | 56 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004708; F:MAP kinase kinase activity; IGI:CGD.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0035690; P:cellular response to drug; IMP:CGD.::GO:0031505; P:fungal-type cell wall organization; IMP:CGD.::GO:0030448; P:hyphal growth; IMP:CGD.::GO:0071507; P:MAPK cascade involved in conjugation with cellular fusion; IMP:CGD. | 959 | Q8QHL3 | 1327 | VGFR1_CHICK Vascular endothelial growth facto... | 108 | 0.8 | 34.3 | 29 | 44 | GO:0005768; C:endosome; IEA:UniProtKB-SubCell.::GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.::GO:0005887; C:integral to plasma membrane; IEA:InterPro. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005021; F:vascular endothelial growth factor-activated receptor activity; IEA:InterPro. | | | | | | | | | | GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0006935; P:chemotaxis; IEA:UniProtKB-KW.::GO:0048010; P:vascular endothelial growth factor receptor signaling pathway; IEA:InterPro. | 960 | Q02858 | 1122 | TIE2_MOUSE Angiopoietin-1 receptor OS=Mus mus... | 80 | 0.81 | 33.9 | 26 | 49 | GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.::GO:0005887; C:integral to plasma membrane; IEA:InterPro. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004714; F:transmembrane receptor protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | GO:0006916; P:anti-apoptosis; IGI:MGI.::GO:0016337; P:cell-cell adhesion; IMP:MGI.::GO:0007160; P:cell-matrix adhesion; IMP:MGI.::GO:0001935; P:endothelial cell proliferation; IMP:UniProtKB.::GO:0060347; P:heart trabecula formation; IMP:UniProtKB.::GO:0030097; P:hemopoiesis; IMP:MGI.::GO:0016525; P:negative regulation of angiogenesis; ISS:UniProtKB.::GO:2000352; P:negative regulation of endothelial cell apoptotic process; IMP:UniProtKB.::GO:0001569; P:patterning of blood vessels; TAS:DFLAT.::GO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:UniProtKB.::GO:0045766; P:positive regulation of angiogenesis; ISS:UniProtKB.::GO:0010595; P:positive regulation of endothelial cell migration; ISS:UniProtKB.::GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; ISS:UniProtKB.::GO:0051894; P:positive regulation of focal adhesion assembly; ISS:UniProtKB.::GO:0033138; P:positive regulation of peptidyl-serine phosphorylation; IGI:MGI.::GO:0043552; P:positive regulation of phosphatidylinositol 3-kinase activity; ISS:UniProtKB.::GO:0014068; P:positive regulation of phosphatidylinositol 3-kinase cascade; ISS:UniProtKB.::GO:0051897; P:positive regulation of protein kinase B signaling cascade; ISS:UniProtKB.::GO:0030949; P:positive regulation of vascular endothelial growth factor receptor signaling pathway; TAS:DFLAT.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0001936; P:regulation of endothelial cell proliferation; TAS:DFLAT.::GO:0032878; P:regulation of establishment or maintenance of cell polarity; ISS:UniProtKB.::GO:0032526; P:response to retinoic acid; IDA:BHF-UCL.::GO:0002040; P:sprouting angiogenesis; ISS:UniProtKB.::GO:0034446; P:substrate adhesion-dependent cell spreading; ISS:UniProtKB.::GO:0048014; P:Tie receptor signaling pathway; ISS:UniProtKB.::GO:0001570; P:vasculogenesis; IMP:UniProtKB. | 961 | Q9W1B0 | 1637 | GEK_DROME Serine/threonine-protein kinase Gen... | 108 | 0.81 | 34.3 | 29 | 41 | GO:0030424; C:axon; IDA:FlyBase.::GO:0030426; C:growth cone; IDA:FlyBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.::GO:0005083; F:small GTPase regulator activity; IEA:InterPro. | | | | | | | | | | GO:0008154; P:actin polymerization or depolymerization; IMP:FlyBase.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0030833; P:regulation of actin filament polymerization; IMP:UniProtKB.::GO:0008039; P:synaptic target recognition; IMP:FlyBase. |