| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | O14089 | 910 | IMB2_SCHPO Importin subunit beta-2 OS=Schizos... | 642 | 6e-146 | 454 | 39 | 59 | GO:0005829; C:cytosol; IDA:PomBase.::GO:0031965; C:nuclear membrane; IDA:PomBase.::GO:0005643; C:nuclear pore; NAS:PomBase. | | | | | | | | | | GO:0005525; F:GTP binding; NAS:PomBase.::GO:0008565; F:protein transporter activity; TAS:PomBase. | | | | | | | | | | GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.::GO:0006913; P:nucleocytoplasmic transport; TAS:PomBase.::GO:0006605; P:protein targeting; NAS:PomBase. | 2 | Q92973 | 898 | TNPO1_HUMAN Transportin-1 OS=Homo sapiens (Hu... | 674 | 8e-138 | 432 | 38 | 57 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; TAS:ProtInc. | | | | | | | | | | GO:0008139; F:nuclear localization sequence binding; TAS:ProtInc.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0008565; F:protein transporter activity; IEA:InterPro. | | | | | | | | | | GO:0010467; P:gene expression; TAS:Reactome.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0016071; P:mRNA metabolic process; TAS:Reactome.::GO:0000060; P:protein import into nucleus, translocation; TAS:ProtInc. | 3 | Q3SYU7 | 898 | TNPO1_BOVIN Transportin-1 OS=Bos taurus (Bovi... | 674 | 1e-137 | 432 | 38 | 57 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005488; F:binding; IEA:InterPro.::GO:0008565; F:protein transporter activity; IEA:InterPro. | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. | 4 | Q8BFY9 | 898 | TNPO1_MOUSE Transportin-1 OS=Mus musculus (Mo... | 674 | 3e-137 | 431 | 37 | 57 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005488; F:binding; IEA:InterPro.::GO:0008565; F:protein transporter activity; IEA:InterPro. | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. | 5 | Q99LG2 | 887 | TNPO2_MOUSE Transportin-2 OS=Mus musculus (Mo... | 672 | 2e-126 | 402 | 36 | 56 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005488; F:binding; IEA:InterPro.::GO:0008565; F:protein transporter activity; IEA:InterPro. | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. | 6 | O14787 | 897 | TNPO2_HUMAN Transportin-2 OS=Homo sapiens (Hu... | 682 | 1e-124 | 398 | 36 | 55 | GO:0005737; C:cytoplasm; TAS:ProtInc.::GO:0005634; C:nucleus; TAS:ProtInc. | | | | | | | | | | GO:0008139; F:nuclear localization sequence binding; TAS:ProtInc.::GO:0008565; F:protein transporter activity; IEA:InterPro. | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. | 7 | Q55CQ7 | 931 | TNPO_DICDI Transportin OS=Dictyostelium disco... | 546 | 3e-91 | 309 | 34 | 54 | GO:0005829; C:cytosol; ISS:dictyBase.::GO:0005635; C:nuclear envelope; ISS:dictyBase. | | | | | | | | | | GO:0008139; F:nuclear localization sequence binding; ISS:dictyBase.::GO:0008565; F:protein transporter activity; IEA:InterPro. | | | | | | | | | | GO:0006606; P:protein import into nucleus; ISS:dictyBase. | 8 | P38217 | 918 | IMB2_YEAST Importin subunit beta-2 OS=Sacchar... | 623 | 1e-84 | 291 | 32 | 53 | GO:0005935; C:cellular bud neck; IDA:SGD.::GO:0005934; C:cellular bud tip; IDA:SGD.::GO:0005829; C:cytosol; IDA:SGD. | | | | | | | | | | GO:0008139; F:nuclear localization sequence binding; IPI:SGD. | | | | | | | | | | GO:0007049; P:cell cycle; IMP:SGD.::GO:0006609; P:mRNA-binding (hnRNP) protein import into nucleus; IDA:SGD.::GO:0042991; P:transcription factor import into nucleus; IMP:SGD. | 9 | O13864 | 863 | IMB1_SCHPO Importin subunit beta-1 OS=Schizos... | 134 | 0.00000000000006 | 79.3 | 30 | 53 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0031965; C:nuclear membrane; IDA:PomBase. | | | | | | | | | | GO:0005525; F:GTP binding; NAS:PomBase.::GO:0005515; F:protein binding; IPI:PomBase.::GO:0008565; F:protein transporter activity; TAS:PomBase. | | | | | | | | | | GO:0051301; P:cell division; IMP:PomBase.::GO:0006913; P:nucleocytoplasmic transport; TAS:PomBase.::GO:0006605; P:protein targeting; NAS:PomBase. | 10 | Q06142 | 861 | IMB1_YEAST Importin subunit beta-1 OS=Sacchar... | 109 | 0.000000000002 | 73.9 | 35 | 58 | GO:0005737; C:cytoplasm; IDA:SGD.::GO:0005643; C:nuclear pore; IDA:SGD. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct.::GO:0008565; F:protein transporter activity; IDA:SGD.::GO:0005087; F:Ran guanyl-nucleotide exchange factor activity; IDA:SGD. | | | | | | | | | | GO:0051292; P:nuclear pore complex assembly; IMP:SGD.::GO:0006656; P:phosphatidylcholine biosynthetic process; IMP:SGD.::GO:0006606; P:protein import into nucleus; IMP:SGD.::GO:0006612; P:protein targeting to membrane; IMP:SGD.::GO:0060188; P:regulation of protein desumoylation; IMP:SGD. | 11 | O00410 | 1097 | IPO5_HUMAN Importin-5 OS=Homo sapiens (Human)... | 136 | 1.5 | 35.8 | 20 | 43 | GO:0005737; C:cytoplasm; TAS:ProtInc.::GO:0005643; C:nuclear pore; TAS:ProtInc.::GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005095; F:GTPase inhibitor activity; TAS:ProtInc.::GO:0008565; F:protein transporter activity; IEA:InterPro.::GO:0008536; F:Ran GTPase binding; TAS:ProtInc. | | | | | | | | | | GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0006607; P:NLS-bearing substrate import into nucleus; TAS:ProtInc.::GO:0006610; P:ribosomal protein import into nucleus; IDA:UniProtKB. | 12 | Q8BKC5 | 1097 | IPO5_MOUSE Importin-5 OS=Mus musculus (Mouse)... | 136 | 1.8 | 35.4 | 20 | 43 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct.::GO:0008565; F:protein transporter activity; IEA:InterPro. | | | | | | | | | | | 13 | O18388 | 884 | IMB_DROME Importin subunit beta OS=Drosophila... | 193 | 0.00000000008 | 68.9 | 28 | 48 | GO:0005811; C:lipid particle; IDA:FlyBase.::GO:0005875; C:microtubule associated complex; IDA:FlyBase.::GO:0005643; C:nuclear pore; ISS:FlyBase. | | | | | | | | | | GO:0005488; F:binding; IEA:InterPro.::GO:0008320; F:protein transmembrane transporter activity; ISS:FlyBase. | | | | | | | | | | GO:0007015; P:actin filament organization; IMP:FlyBase.::GO:0007304; P:chorion-containing eggshell formation; IMP:FlyBase.::GO:0007067; P:mitosis; IMP:FlyBase.::GO:0006607; P:NLS-bearing substrate import into nucleus; IDA:FlyBase.::GO:0051533; P:positive regulation of NFAT protein import into nucleus; IMP:FlyBase.::GO:0000059; P:protein import into nucleus, docking; IDA:FlyBase.::GO:0008360; P:regulation of cell shape; IMP:FlyBase. | 14 | Q8BIV3 | 1105 | RNBP6_MOUSE Ran-binding protein 6 OS=Mus musc... | 127 | 0.27 | 38.1 | 20 | 43 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005488; F:binding; IEA:InterPro. | | | | | | | | | | GO:0015031; P:protein transport; IEA:UniProtKB-KW. | 15 | O74476 | 1095 | IMB3_SCHPO Importin subunit beta-3 OS=Schizos... | 260 | 0.0000000002 | 68.2 | 27 | 46 | GO:0005829; C:cytosol; IDA:PomBase.::GO:0031965; C:nuclear membrane; IDA:PomBase. | | | | | | | | | | GO:0005525; F:GTP binding; NAS:PomBase.::GO:0008565; F:protein transporter activity; TAS:PomBase. | | | | | | | | | | GO:0006606; P:protein import into nucleus; IDA:PomBase.::GO:0007346; P:regulation of mitotic cell cycle; IMP:PomBase. | 16 | P70168 | 876 | IMB1_MOUSE Importin subunit beta-1 OS=Mus mus... | 145 | 0.0000000005 | 66.6 | 28 | 50 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0043234; C:protein complex; IDA:MGI. | | | | | | | | | | GO:0008565; F:protein transporter activity; IDA:MGI. | | | | | | | | | | GO:0006610; P:ribosomal protein import into nucleus; IDA:MGI. | 17 | P52296 | 875 | IMB1_RAT Importin subunit beta-1 OS=Rattus no... | 145 | 0.0000000005 | 66.6 | 28 | 50 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 18 | O60518 | 1105 | RNBP6_HUMAN Ran-binding protein 6 OS=Homo sap... | 127 | 0.27 | 38.1 | 20 | 43 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005488; F:binding; IEA:InterPro. | | | | | | | | | | GO:0015031; P:protein transport; IEA:UniProtKB-KW. | 19 | Q14974 | 876 | IMB1_HUMAN Importin subunit beta-1 OS=Homo sa... | 145 | 0.000000001 | 65.1 | 29 | 48 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0031965; C:nuclear membrane; IDA:HPA.::GO:0005643; C:nuclear pore; TAS:ProtInc.::GO:0005654; C:nucleoplasm; TAS:Reactome. | | | | | | | | | | GO:0008139; F:nuclear localization sequence binding; TAS:ProtInc.::GO:0019904; F:protein domain specific binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; TAS:ProtInc. | | | | | | | | | | GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.::GO:0006309; P:DNA fragmentation involved in apoptotic nuclear change; TAS:Reactome.::GO:0006607; P:NLS-bearing substrate import into nucleus; TAS:ProtInc.::GO:0000060; P:protein import into nucleus, translocation; TAS:ProtInc.::GO:0006610; P:ribosomal protein import into nucleus; IDA:UniProtKB.::GO:0046796; P:viral genome transport in host cell; TAS:Reactome.::GO:0019058; P:viral infectious cycle; TAS:Reactome. | 20 | Q8TEX9 | 1081 | IPO4_HUMAN Importin-4 OS=Homo sapiens (Human)... | 476 | 0.000004 | 53.9 | 22 | 41 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005488; F:binding; IEA:InterPro.::GO:0008565; F:protein transporter activity; IEA:InterPro. | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. | 21 | Q8VI75 | 1082 | IPO4_MOUSE Importin-4 OS=Mus musculus (Mouse)... | 139 | 1.3 | 36.2 | 22 | 41 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008565; F:protein transporter activity; IEA:InterPro. | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. | 22 | P32337 | 1089 | IMB3_YEAST Importin subunit beta-3 OS=Sacchar... | 216 | 0.00002 | 51.6 | 26 | 50 | GO:0005737; C:cytoplasm; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD. | | | | | | | | | | GO:0008139; F:nuclear localization sequence binding; IDA:SGD.::GO:0008565; F:protein transporter activity; IMP:SGD. | | | | | | | | | | GO:0006406; P:mRNA export from nucleus; IGI:SGD.::GO:0006606; P:protein import into nucleus; IMP:SGD.::GO:0007088; P:regulation of mitosis; IMP:SGD.::GO:0060188; P:regulation of protein desumoylation; IMP:SGD. | 23 | P40069 | 1113 | IMB4_YEAST Importin subunit beta-4 OS=Sacchar... | 326 | 0.002 | 45.4 | 24 | 40 | GO:0005737; C:cytoplasm; IDA:SGD.::GO:0005643; C:nuclear pore; IDA:SGD. | | | | | | | | | | GO:0008139; F:nuclear localization sequence binding; IDA:SGD.::GO:0008565; F:protein transporter activity; IMP:SGD. | | | | | | | | | | GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.::GO:0006607; P:NLS-bearing substrate import into nucleus; IMP:SGD.::GO:2000220; P:regulation of pseudohyphal growth; IMP:SGD.::GO:0006610; P:ribosomal protein import into nucleus; IMP:SGD. | 24 | P25997 | 1050 | EF3_CANAL Elongation factor 3 OS=Candida albi... | 156 | 0.003 | 44.3 | 27 | 45 | GO:0009986; C:cell surface; IDA:CGD.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IDA:CGD.::GO:0030445; C:yeast-form cell wall; IDA:CGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016887; F:ATPase activity; IDA:CGD.::GO:0003924; F:GTPase activity; ISS:CGD.::GO:0003746; F:translation elongation factor activity; IGI:CGD. | | | | | | | | | | | 25 | Q54EW3 | 1067 | IPO5_DICDI Probable importin-5 homolog OS=Dic... | 63 | 0.033 | 41.2 | 25 | 49 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005488; F:binding; IEA:InterPro. | | | | | | | | | | GO:0015031; P:protein transport; IEA:UniProtKB-KW. | 26 | O60100 | 1067 | IMB4_SCHPO Probable importin subunit beta-4 O... | 216 | 0.034 | 41.2 | 23 | 40 | GO:0005829; C:cytosol; IDA:PomBase.::GO:0005635; C:nuclear envelope; IDA:PomBase. | | | | | | | | | | GO:0005488; F:binding; IEA:InterPro.::GO:0008565; F:protein transporter activity; TAS:PomBase. | | | | | | | | | | GO:0006913; P:nucleocytoplasmic transport; TAS:PomBase.::GO:0006605; P:protein targeting; NAS:PomBase. | 27 | Q5R6J0 | 1810 | ECM29_PONAB Proteasome-associated protein ECM... | 106 | 0.035 | 41.2 | 25 | 47 | GO:0030139; C:endocytic vesicle; ISS:UniProtKB.::GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005793; C:endoplasmic reticulum-Golgi intermediate compartment; IEA:UniProtKB-SubCell.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0005771; C:multivesicular body; ISS:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0000502; C:proteasome complex; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005488; F:binding; IEA:InterPro. | | | | | | | | | | | 28 | Q6PDI5 | 1840 | ECM29_MOUSE Proteasome-associated protein ECM... | 106 | 0.058 | 40.4 | 25 | 47 | GO:0030139; C:endocytic vesicle; ISS:UniProtKB.::GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005793; C:endoplasmic reticulum-Golgi intermediate compartment; IEA:UniProtKB-SubCell.::GO:0005771; C:multivesicular body; ISS:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0000502; C:proteasome complex; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005488; F:binding; IEA:InterPro. | | | | | | | | | | | 29 | Q5VYK3 | 1845 | ECM29_HUMAN Proteasome-associated protein ECM... | 106 | 0.067 | 40.4 | 25 | 47 | GO:0005813; C:centrosome; IDA:UniProtKB.::GO:0005769; C:early endosome; IDA:UniProtKB.::GO:0030139; C:endocytic vesicle; IDA:UniProtKB.::GO:0005783; C:endoplasmic reticulum; IDA:UniProtKB.::GO:0005793; C:endoplasmic reticulum-Golgi intermediate compartment; IEA:UniProtKB-SubCell.::GO:0030134; C:ER to Golgi transport vesicle; IDA:UniProtKB.::GO:0005771; C:multivesicular body; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0000502; C:proteasome complex; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005488; F:binding; IEA:InterPro. | | | | | | | | | | GO:0030433; P:ER-associated protein catabolic process; IMP:UniProtKB. | 30 | Q92616 | 2671 | GCN1L_HUMAN Translational activator GCN1 OS=H... | 86 | 5.3 | 34.3 | 27 | 43 | GO:0005840; C:ribosome; NAS:UniProtKB. | | | | | | | | | | GO:0008135; F:translation factor activity, nucleic acid binding; NAS:UniProtKB. | | | | | | | | | | GO:0006417; P:regulation of translation; IEA:UniProtKB-KW. | 31 | P41814 | 478 | TRM6_YEAST tRNA (adenine(58)-N(1))-methyltran... | 78 | 0.85 | 36.6 | 31 | 44 | GO:0005634; C:nucleus; IDA:SGD.::GO:0031515; C:tRNA (m1A) methyltransferase complex; IDA:SGD. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct.::GO:0003743; F:translation initiation factor activity; IEA:InterPro. | | | | | | | | | | GO:0006446; P:regulation of translational initiation; IEA:InterPro.::GO:0030488; P:tRNA methylation; IDA:SGD. |
