Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Candida albicans WO1
Locus:
CAWG_00744
Length:
291
Number of sequences:
5931
Description:
conserved hypothetical protein
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
91Q9NZM3    1697   ITSN2_HUMAN Intersectin-2 OS=Homo sapiens (Hu...380.85     35     34     58GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.::GO:0005070; F:SH3/SH2 adaptor activity; TAS:ProtInc.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.
92Q6GM14    376   DBNLB_XENLA Drebrin-like protein B OS=Xenopus...350.88     34.7     40     69GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.
93Q9WVE9    1217   ITSN1_RAT Intersectin-1 OS=Rattus norvegicus ...380.91     35     37     58GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-KW.::GO:0045202; C:synapse; IEA:UniProtKB-KW.::GO:0019717; C:synaptosome; IEA:UniProtKB-SubCell.
GO:0005509; F:calcium ion binding; IEA:InterPro.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0006887; P:exocytosis; TAS:RGD.
94Q5A895    498   HSE1_CANAL Class E vacuolar protein-sorting m...390.91     34.7     38     56GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.
GO:0006886; P:intracellular protein transport; IEA:InterPro.
95Q15080    339   NCF4_HUMAN Neutrophil cytosol factor 4 OS=Hom...380.98     34.3     37     63GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0043020; C:NADPH oxidase complex; IDA:UniProtKB.::GO:0032010; C:phagolysosome; TAS:Reactome.
GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.::GO:0046983; F:protein dimerization activity; TAS:UniProtKB.
GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.::GO:0007154; P:cell communication; IEA:InterPro.::GO:0006955; P:immune response; TAS:UniProtKB.::GO:0055114; P:oxidation-reduction process; TAS:UniProtKB.
96Q2KI13    747   SGSM3_BOVIN Small G protein signaling modulat...391     34.7     38     62GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005097; F:Rab GTPase activator activity; IEA:InterPro.::GO:0017137; F:Rab GTPase binding; ISS:UniProtKB.
GO:0007050; P:cell cycle arrest; IEA:UniProtKB-KW.::GO:0032486; P:Rap protein signal transduction; ISS:UniProtKB.
97Q96HU1    749   SGSM3_HUMAN Small G protein signaling modulat...391     34.7     38     62GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005097; F:Rab GTPase activator activity; IEA:InterPro.::GO:0017137; F:Rab GTPase binding; IDA:UniProtKB.
GO:0007050; P:cell cycle arrest; IEA:UniProtKB-KW.::GO:0032486; P:Rap protein signal transduction; IEP:UniProtKB.
98C5DQY5    371   SHO1_ZYGRC High osmolarity signaling protein ...411.1     34.3     39     61GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.
99Q7ZXQ9    447   DBNLA_XENLA Drebrin-like protein A OS=Xenopus...371.1     34.3     35     57GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.
100Q5HYK7    790   SH319_HUMAN SH3 domain-containing protein 19 ...371.1     34.7     41     59GO:0005829; C:cytosol; TAS:Reactome.::GO:0005794; C:Golgi apparatus; IDA:HPA.::GO:0005634; C:nucleus; IDA:HPA.::GO:0005886; C:plasma membrane; IDA:BHF-UCL.
GO:0070064; F:proline-rich region binding; IPI:BHF-UCL.
GO:0016044; P:cellular membrane organization; TAS:Reactome.::GO:0007010; P:cytoskeleton organization; IMP:UniProtKB.::GO:0051044; P:positive regulation of membrane protein ectodomain proteolysis; IMP:BHF-UCL.::GO:0006892; P:post-Golgi vesicle-mediated transport; TAS:Reactome.::GO:0022604; P:regulation of cell morphogenesis; IMP:UniProtKB.
101Q3U1V8    1077   M3K9_MOUSE Mitogen-activated protein kinase k...391.2     34.7     44     59
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004709; F:MAP kinase kinase kinase activity; IEA:EC.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006950; P:response to stress; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
102Q9R1Z8    733   VINEX_MOUSE Vinexin OS=Mus musculus (Mouse). ...361.3     34.3     36     58GO:0005737; C:cytoplasm; IDA:MGI.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IDA:MGI.::GO:0005634; C:nucleus; IDA:MGI.
GO:0008134; F:transcription factor binding; IPI:MGI.
GO:0031589; P:cell-substrate adhesion; IDA:MGI.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:MGI.::GO:0043410; P:positive regulation of MAPK cascade; IDA:MGI.
103P18010    633   IPAA_SHIFL Invasin ipaA OS=Shigella flexneri....991.4     34.3     32     44GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0017166; F:vinculin binding; IPI:UniProtKB.
GO:0009405; P:pathogenesis; IEA:UniProtKB-KW.::GO:0030836; P:positive regulation of actin filament depolymerization; IDA:UniProtKB.
104P80192    1104   M3K9_HUMAN Mitogen-activated protein kinase k...391.4     34.3     44     59
GO:0005524; F:ATP binding; NAS:UniProtKB.::GO:0004706; F:JUN kinase kinase kinase activity; ISS:UniProtKB.::GO:0004708; F:MAP kinase kinase activity; NAS:UniProtKB.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro.
GO:0007257; P:activation of JUN kinase activity; ISS:UniProtKB.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
105O60504    671   VINEX_HUMAN Vinexin OS=Homo sapiens (Human). ...361.5     34.3     33     61GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0005200; F:structural constituent of cytoskeleton; TAS:ProtInc.::GO:0017166; F:vinculin binding; IPI:UniProtKB.
GO:0006936; P:muscle contraction; TAS:Reactome.::GO:0051496; P:positive regulation of stress fiber assembly; IDA:UniProtKB.
106O70589    926   CSKP_MOUSE Peripheral plasma membrane protein...311.5     34.3     42     61GO:0016323; C:basolateral plasma membrane; IDA:MGI.::GO:0005911; C:cell-cell junction; IDA:BHF-UCL.::GO:0005829; C:cytosol; IDA:MGI.::GO:0005634; C:nucleus; IDA:BHF-UCL.::GO:0045202; C:synapse; IDA:MGI.::GO:0019717; C:synaptosome; IDA:MGI.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IGI:MGI.
107O14936    926   CSKP_HUMAN Peripheral plasma membrane protein...311.6     34.3     42     61GO:0015629; C:actin cytoskeleton; TAS:ProtInc.::GO:0005911; C:cell-cell junction; IDA:BHF-UCL.::GO:0060170; C:cilium membrane; ISS:BHF-UCL.::GO:0005737; C:cytoplasm; IDA:BHF-UCL.::GO:0005652; C:nuclear lamina; IDA:BHF-UCL.::GO:0016363; C:nuclear matrix; IDA:BHF-UCL.::GO:0005730; C:nucleolus; IDA:BHF-UCL.::GO:0042734; C:presynaptic membrane; ISS:BHF-UCL.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004385; F:guanylate kinase activity; TAS:ProtInc.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007155; P:cell adhesion; TAS:ProtInc.::GO:0001953; P:negative regulation of cell-matrix adhesion; IMP:BHF-UCL.::GO:0090288; P:negative regulation of cellular response to growth factor stimulus; IMP:BHF-UCL.::GO:0010839; P:negative regulation of keratinocyte proliferation; IMP:BHF-UCL.::GO:0061045; P:negative regulation of wound healing; IMP:BHF-UCL.
108Q62915    909   CSKP_RAT Peripheral plasma membrane protein C...311.6     34.3     42     61GO:0060170; C:cilium membrane; IDA:BHF-UCL.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0030425; C:dendrite; IDA:RGD.::GO:0005624; C:membrane fraction; IDA:RGD.::GO:0005634; C:nucleus; IDA:BHF-UCL.::GO:0042734; C:presynaptic membrane; IDA:BHF-UCL.::GO:0043234; C:protein complex; IDA:RGD.::GO:0005625; C:soluble fraction; IDA:RGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; TAS:RGD.::GO:0004683; F:calmodulin-dependent protein kinase activity; TAS:RGD.::GO:0030165; F:PDZ domain binding; IPI:RGD.::GO:0008022; F:protein C-terminus binding; IMP:RGD.::GO:0032403; F:protein complex binding; IPI:RGD.::GO:0003713; F:transcription coactivator activity; TAS:RGD.
GO:0006886; P:intracellular protein transport; IMP:RGD.::GO:0006461; P:protein complex assembly; TAS:RGD.
109Q8K3E5    1047   AHI1_MOUSE Jouberin OS=Mus musculus (Mouse). ...341.8     33.9     38     65GO:0005912; C:adherens junction; ISS:UniProtKB.::GO:0005911; C:cell-cell junction; ISS:UniProtKB.::GO:0005814; C:centriole; IDA:UniProtKB.::GO:0005932; C:microtubule basal body; IDA:UniProtKB.::GO:0036038; C:TCTN-B9D complex; IDA:UniProtKB.
GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0042384; P:cilium assembly; IMP:UniProtKB.::GO:0035844; P:cloaca development; IGI:UniProtKB.::GO:0001947; P:heart looping; IGI:UniProtKB.::GO:0030902; P:hindbrain development; IGI:UniProtKB.::GO:0070121; P:Kupffer's vesicle development; ISS:UniProtKB.::GO:0070986; P:left/right axis specification; ISS:UniProtKB.::GO:0001738; P:morphogenesis of a polarized epithelium; IMP:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.::GO:0071599; P:otic vesicle development; IGI:UniProtKB.::GO:0035845; P:photoreceptor cell outer segment organization; IGI:UniProtKB.::GO:0030862; P:positive regulation of polarized epithelial cell differentiation; IMP:UniProtKB.::GO:0002092; P:positive regulation of receptor internalization; IMP:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:UniProtKB.::GO:0039023; P:pronephric duct morphogenesis; ISS:UniProtKB.::GO:0039008; P:pronephric nephron tubule morphogenesis; IGI:UniProtKB.::GO:0033365; P:protein localization to organelle; IMP:UniProtKB.::GO:0050795; P:regulation of behavior; IMP:UniProtKB.::GO:0010842; P:retina layer formation; IGI:UniProtKB.::GO:0065001; P:specification of axis polarity; IGI:UniProtKB.::GO:0007169; P:transmembrane receptor protein tyrosine kinase signaling pathway; IMP:UniProtKB.::GO:0016192; P:vesicle-mediated transport; IMP:UniProtKB.
110O35964    368   SH3G1_RAT Endophilin-A2 OS=Rattus norvegicus ...371.8     33.5     35     62GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0005626; C:insoluble fraction; IDA:RGD.::GO:0005625; C:soluble fraction; IDA:RGD.
GO:0051020; F:GTPase binding; IPI:RGD.::GO:0008289; F:lipid binding; IEA:UniProtKB-KW.::GO:0019902; F:phosphatase binding; IPI:RGD.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
111Q6DTM3    1047   AHI1_RAT Jouberin OS=Rattus norvegicus (Rat)....341.9     33.9     41     62GO:0005912; C:adherens junction; ISS:UniProtKB.::GO:0005911; C:cell-cell junction; ISS:UniProtKB.::GO:0005814; C:centriole; ISS:UniProtKB.::GO:0005932; C:microtubule basal body; ISS:UniProtKB.::GO:0036038; C:TCTN-B9D complex; ISS:UniProtKB.
GO:0042384; P:cilium assembly; ISS:UniProtKB.::GO:0035844; P:cloaca development; ISS:UniProtKB.::GO:0001947; P:heart looping; ISS:UniProtKB.::GO:0030902; P:hindbrain development; ISS:UniProtKB.::GO:0070121; P:Kupffer's vesicle development; ISS:UniProtKB.::GO:0070986; P:left/right axis specification; ISS:UniProtKB.::GO:0001738; P:morphogenesis of a polarized epithelium; ISS:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0071599; P:otic vesicle development; ISS:UniProtKB.::GO:0035845; P:photoreceptor cell outer segment organization; ISS:UniProtKB.::GO:0030862; P:positive regulation of polarized epithelial cell differentiation; ISS:UniProtKB.::GO:0002092; P:positive regulation of receptor internalization; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0039023; P:pronephric duct morphogenesis; ISS:UniProtKB.::GO:0039008; P:pronephric nephron tubule morphogenesis; ISS:UniProtKB.::GO:0050795; P:regulation of behavior; ISS:UniProtKB.::GO:0010842; P:retina layer formation; ISS:UniProtKB.::GO:0065001; P:specification of axis polarity; ISS:UniProtKB.::GO:0007169; P:transmembrane receptor protein tyrosine kinase signaling pathway; ISS:UniProtKB.::GO:0016192; P:vesicle-mediated transport; ISS:UniProtKB.
112Q62419    368   SH3G1_MOUSE Endophilin-A2 OS=Mus musculus (Mo...372     33.5     35     62GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.
GO:0008289; F:lipid binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:MGI.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
113O94875    1100   SRBS2_HUMAN Sorbin and SH3 domain-containing ...342.2     33.5     35     62GO:0015629; C:actin cytoskeleton; TAS:ProtInc.::GO:0005622; C:intracellular; IEA:InterPro.::GO:0005634; C:nucleus; NAS:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0030018; C:Z disc; NAS:UniProtKB.
GO:0008093; F:cytoskeletal adaptor activity; TAS:ProtInc.::GO:0005200; F:structural constituent of cytoskeleton; TAS:ProtInc.::GO:0008307; F:structural constituent of muscle; TAS:ProtInc.::GO:0008270; F:zinc ion binding; IEA:InterPro.
114Q99963    347   SH3G3_HUMAN Endophilin-A3 OS=Homo sapiens (Hu...372.9     33.1     32     65GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.
GO:0042802; F:identical protein binding; IPI:IntAct.::GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
GO:0007417; P:central nervous system development; TAS:ProtInc.::GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0007165; P:signal transduction; TAS:ProtInc.
115Q9Z0R4    1714   ITSN1_MOUSE Intersectin-1 OS=Mus musculus (Mo...382.9     33.5     34     58GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0030139; C:endocytic vesicle; IDA:MGI.::GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IDA:MGI.::GO:0016020; C:membrane; IEA:UniProtKB-KW.::GO:0045202; C:synapse; IEA:UniProtKB-KW.::GO:0019717; C:synaptosome; IEA:UniProtKB-SubCell.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0019209; F:kinase activator activity; IDA:MGI.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0043524; P:negative regulation of neuron apoptotic process; IMP:MGI.::GO:0051897; P:positive regulation of protein kinase B signaling cascade; IDA:MGI.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IDA:MGI.
116Q71F54    894   SH3R1_RAT E3 ubiquitin-protein ligase SH3RF1 ...342.9     33.1     41     62GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006917; P:induction of apoptosis; IMP:RGD.
117Q07883    217   GRB2_CHICK Growth factor receptor-bound prote...343     32.7     38     59GO:0005768; C:endosome; ISS:UniProtKB.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB.
118Q6XJU9    214   OSTF1_MONAL Osteoclast-stimulating factor 1 O...453.3     32.3     31     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
119C5MB30    340   SHO1_CANTT High osmolarity signaling protein ...393.3     32.7     41     64GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.
120Q69ZI1    892   SH3R1_MOUSE E3 ubiquitin-protein ligase SH3RF...343.3     33.1     41     62GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IDA:MGI.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0005078; F:MAP-kinase scaffold activity; IDA:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0046328; P:regulation of JNK cascade; IDA:MGI.
121Q8BTE0    104   CF057_MOUSE UPF0369 protein C6orf57 homolog O...563.4     31.2     36     48GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.::GO:0005739; C:mitochondrion; IDA:MGI.
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