rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
61 | Q99LB2 | 279 | DHRS4_MOUSE Dehydrogenase/reductase SDR famil... | 232 | 0.0009 | 44.7 | 24 | 43 | GO:0005739; C:mitochondrion; IDA:UniProtKB.::GO:0005777; C:peroxisome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004090; F:carbonyl reductase (NADPH) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | | 62 | P25145 | 248 | Y432_LISMO Uncharacterized oxidoreductase Lmo... | 225 | 0.001 | 44.3 | 25 | 39 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 63 | Q6QLL4 | 300 | DHI1_CAVPO Corticosteroid 11-beta-dehydrogena... | 68 | 0.001 | 44.3 | 34 | 57 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0070524; F:11-beta-hydroxysteroid dehydrogenase (NADP+) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0008202; P:steroid metabolic process; IEA:UniProtKB-KW. | 64 | Q05016 | 267 | YM71_YEAST Uncharacterized oxidoreductase YMR... | 228 | 0.001 | 44.3 | 22 | 42 | GO:0005737; C:cytoplasm; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD. | | | | | | | | | | GO:0004090; F:carbonyl reductase (NADPH) activity; IDA:SGD.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016620; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor; IDA:SGD. | | | | | | | | | | | 65 | Q00791 | 264 | STCU_EMENI Versicolorin reductase OS=194 / M1... | 125 | 0.001 | 43.9 | 27 | 49 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 66 | O02691 | 261 | HCD2_BOVIN 3-hydroxyacyl-CoA dehydrogenase ty... | 232 | 0.001 | 43.9 | 25 | 40 | | | | | | | | | | | GO:0047015; F:3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity; IEA:EC.::GO:0003857; F:3-hydroxyacyl-CoA dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0008033; P:tRNA processing; IEA:UniProtKB-KW. | 67 | P87025 | 272 | THR1_GLOLA Trihydroxynaphthalene reductase OS... | 145 | 0.002 | 43.9 | 28 | 46 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0042438; P:melanin biosynthetic process; IEA:UniProtKB-KW. | 68 | Q9Y140 | 326 | DHRS7_DROME Dehydrogenase/reductase SDR famil... | 121 | 0.002 | 43.9 | 29 | 45 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005778; C:peroxisomal membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 69 | Q4A054 | 234 | Y0419_STAS1 Uncharacterized oxidoreductase SS... | 239 | 0.002 | 43.5 | 22 | 41 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 70 | Q6F7B8 | 303 | ACR1_ACIAD Fatty acyl-CoA reductase OS=Acinet... | 138 | 0.002 | 43.5 | 25 | 45 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016620; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor; IEA:EC. | | | | | | | | | | GO:0006629; P:lipid metabolic process; IEA:UniProtKB-KW. | 71 | P94129 | 295 | ACR1_ACIBI Fatty acyl-CoA reductase OS=Acinet... | 138 | 0.002 | 43.5 | 25 | 45 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016620; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor; IEA:EC. | | | | | | | | | | GO:0006629; P:lipid metabolic process; IEA:UniProtKB-KW. | 72 | P39577 | 252 | DLTE_BACSU Uncharacterized oxidoreductase dlt... | 147 | 0.003 | 43.1 | 28 | 50 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 73 | Q92EK7 | 248 | Y452_LISIN Uncharacterized oxidoreductase Lin... | 225 | 0.003 | 42.7 | 25 | 39 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 74 | Q03131 | 3491 | ERYA1_SACER Erythronolide synthase, modules 1... | 84 | 0.004 | 43.5 | 35 | 54 | | | | | | | | | | | GO:0000036; F:acyl carrier activity; IEA:InterPro.::GO:0048037; F:cofactor binding; IEA:InterPro.::GO:0047879; F:erythronolide synthase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0031177; F:phosphopantetheine binding; IEA:InterPro. | | | | | | | | | | GO:0017000; P:antibiotic biosynthetic process; IEA:UniProtKB-KW. | 75 | Q2KIJ5 | 331 | KDSR_BOVIN 3-ketodihydrosphingosine reductase... | 222 | 0.004 | 42.7 | 25 | 41 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0047560; F:3-dehydrosphinganine reductase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | | 76 | P50172 | 292 | DHI1_MOUSE Corticosteroid 11-beta-dehydrogena... | 61 | 0.006 | 42.4 | 34 | 57 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0070524; F:11-beta-hydroxysteroid dehydrogenase (NADP+) activity; IEA:EC.::GO:0003845; F:11-beta-hydroxysteroid dehydrogenase [NAD(P) activity; IDA:MGI.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0030324; P:lung development; IMP:MGI.::GO:0008202; P:steroid metabolic process; IEA:UniProtKB-KW.] | 77 | Q6R0J2 | 292 | DHI1_MESAU Corticosteroid 11-beta-dehydrogena... | 61 | 0.009 | 41.6 | 34 | 57 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0070524; F:11-beta-hydroxysteroid dehydrogenase (NADP+) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0008202; P:steroid metabolic process; IEA:UniProtKB-KW. | 78 | Q05A13 | 316 | S16C6_MOUSE Short-chain dehydrogenase/reducta... | 176 | 0.009 | 41.6 | 26 | 42 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 79 | P51975 | 292 | DHI1_SHEEP Corticosteroid 11-beta-dehydrogena... | 68 | 0.01 | 41.6 | 32 | 56 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0070524; F:11-beta-hydroxysteroid dehydrogenase (NADP+) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0008202; P:steroid metabolic process; IEA:UniProtKB-KW. | 80 | P28845 | 292 | DHI1_HUMAN Corticosteroid 11-beta-dehydrogena... | 62 | 0.01 | 41.6 | 37 | 61 | GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0070524; F:11-beta-hydroxysteroid dehydrogenase (NADP+) activity; IEA:EC.::GO:0003845; F:11-beta-hydroxysteroid dehydrogenase [NAD(P) activity; TAS:Reactome.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006704; P:glucocorticoid biosynthetic process; TAS:Reactome.::GO:0044281; P:small molecule metabolic process; TAS:Reactome.] | 81 | Q4L8Y1 | 231 | Y0585_STAHJ Uncharacterized oxidoreductase SH... | 230 | 0.011 | 41.2 | 23 | 40 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 82 | O70351 | 261 | HCD2_RAT 3-hydroxyacyl-CoA dehydrogenase type... | 232 | 0.011 | 41.2 | 24 | 41 | | | | | | | | | | | GO:0047015; F:3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity; IEA:EC.::GO:0003857; F:3-hydroxyacyl-CoA dehydrogenase activity; IEA:EC.::GO:0018454; F:acetoacetyl-CoA reductase activity; IDA:RGD.::GO:0001540; F:beta-amyloid binding; IDA:RGD.::GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IDA:RGD.::GO:0030331; F:estrogen receptor binding; IPI:RGD.::GO:0042802; F:identical protein binding; IDA:RGD.::GO:0051287; F:NAD binding; IDA:RGD.::GO:0005496; F:steroid binding; IDA:RGD. | | | | | | | | | | GO:0007569; P:cell aging; IEP:RGD.::GO:0033327; P:Leydig cell differentiation; IEP:RGD.::GO:0051289; P:protein homotetramerization; IDA:RGD.::GO:0008033; P:tRNA processing; IEA:UniProtKB-KW. | 83 | Q6PUF3 | 287 | DHI1L_DANRE Hydroxysteroid 11-beta-dehydrogen... | 41 | 0.011 | 41.2 | 39 | 63 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016229; F:steroid dehydrogenase activity; ISS:ZFIN. | | | | | | | | | | | 84 | O33292 | 272 | Y2750_MYCTU Uncharacterized oxidoreductase Rv... | 238 | 0.012 | 41.2 | 24 | 37 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 85 | O07575 | 289 | YHDF_BACSU Uncharacterized oxidoreductase yhd... | 227 | 0.018 | 40.8 | 23 | 40 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 86 | Q06136 | 332 | KDSR_HUMAN 3-ketodihydrosphingosine reductase... | 125 | 0.018 | 40.8 | 25 | 47 | GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0005615; C:extracellular space; TAS:ProtInc.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0047560; F:3-dehydrosphinganine reductase activity; IDA:MGI.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006666; P:3-keto-sphinganine metabolic process; IDA:MGI.::GO:0030148; P:sphingolipid biosynthetic process; TAS:Reactome. | 87 | Q7RZR2 | 325 | TSC10_NEUCR 3-ketodihydrosphingosine reductas... | 127 | 0.024 | 40.4 | 24 | 43 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0047560; F:3-dehydrosphinganine reductase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | | 88 | Q7M3I4 | 292 | DHI1_RABIT Corticosteroid 11-beta-dehydrogena... | 49 | 0.025 | 40 | 35 | 61 | GO:0005789; C:endoplasmic reticulum membrane; NAS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IDA:UniProtKB. | | | | | | | | | | GO:0070524; F:11-beta-hydroxysteroid dehydrogenase (NADP+) activity; IEA:EC.::GO:0003845; F:11-beta-hydroxysteroid dehydrogenase [NAD(P) activity; IDA:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0008211; P:glucocorticoid metabolic process; NAS:UniProtKB.] | 89 | P16232 | 288 | DHI1_RAT Corticosteroid 11-beta-dehydrogenase... | 60 | 0.027 | 40 | 33 | 55 | GO:0045177; C:apical part of cell; IDA:RGD.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IDA:RGD.::GO:0031965; C:nuclear membrane; IDA:RGD.::GO:0005791; C:rough endoplasmic reticulum; IDA:RGD. | | | | | | | | | | GO:0070524; F:11-beta-hydroxysteroid dehydrogenase (NADP+) activity; IEA:EC.::GO:0003845; F:11-beta-hydroxysteroid dehydrogenase [NAD(P) activity; IDA:RGD.::GO:0050661; F:NADP binding; IDA:RGD.::GO:0005496; F:steroid binding; IPI:RGD. | | | | | | | | | | GO:0071392; P:cellular response to estradiol stimulus; IEP:RGD.::GO:0006704; P:glucocorticoid biosynthetic process; IDA:RGD.::GO:0006713; P:glucocorticoid catabolic process; IDA:RGD.::GO:0018963; P:phthalate metabolic process; IEP:RGD.::GO:0043456; P:regulation of pentose-phosphate shunt; IDA:RGD.::GO:0031667; P:response to nutrient levels; IEP:RGD.] | 90 | Q59RQ2 | 271 | TSC10_CANAL 3-ketodihydrosphingosine reductas... | 121 | 0.028 | 40 | 26 | 45 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0047560; F:3-dehydrosphinganine reductase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | | 91 | P50166 | 282 | ARDH_CANTR D-arabinitol 2-dehydrogenase [ribu... | 238 | 0.041 | 39.7 | 21 | 39 | | | | | | | | | | | GO:0047038; F:D-arabinitol 2-dehydrogenase activity; IDA:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0005975; P:carbohydrate metabolic process; IDA:UniProtKB. |