rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
91 | Q7SXW3 | 601 | LRC40_DANRE Leucine-rich repeat-containing pr... | 273 | 0.14 | 38.5 | 28 | 45 | | | | | | | | | | | | | | | | | | | | | | 92 | Q9DAP0 | 323 | LRC46_MOUSE Leucine-rich repeat-containing pr... | 87 | 3.1 | 33.9 | 32 | 56 | | | | | | | | | | | | | | | | | | | | | | 93 | Q7ZV84 | 555 | DAAF1_DANRE Dynein assembly factor 1, axonema... | 160 | 1.9 | 35 | 23 | 49 | GO:0035085; C:cilium axoneme; ISS:UniProtKB. | | | | | | | | | | GO:0045502; F:dynein binding; IMP:UniProtKB. | | | | | | | | | | GO:0003305; P:cell migration involved in heart jogging; IMP:ZFIN.::GO:0001539; P:ciliary or flagellar motility; IMP:ZFIN.::GO:0035083; P:cilium axoneme assembly; IMP:ZFIN.::GO:0060027; P:convergent extension involved in gastrulation; IMP:ZFIN.::GO:0001947; P:heart looping; IMP:ZFIN.::GO:0003314; P:heart rudiment morphogenesis; IMP:ZFIN.::GO:0048793; P:pronephros development; IMP:ZFIN. | 94 | A8WWH5 | 439 | POP1_CAEBR Protein pop-1 OS=Caenorhabditis br... | 82 | 0.16 | 38.1 | 28 | 51 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0008356; P:asymmetric cell division; ISS:UniProtKB.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. | 95 | Q8MTI2 | 625 | BSL1_TRIVA Putative surface protein bspA-like... | 85 | 0.17 | 38.5 | 26 | 54 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 96 | Q8R1Z4 | 357 | PPR42_MOUSE Protein phosphatase 1 regulatory ... | 77 | 0.19 | 37.7 | 32 | 51 | GO:0005813; C:centrosome; IDA:UniProtKB.::GO:0002177; C:manchette; IDA:UniProtKB. | | | | | | | | | | GO:0003779; F:actin binding; IDA:UniProtKB.::GO:0045502; F:dynein binding; IDA:UniProtKB.::GO:0015631; F:tubulin binding; IDA:UniProtKB. | | | | | | | | | | GO:0010921; P:regulation of phosphatase activity; IDA:UniProtKB. | 97 | Q94481 | 744 | CIGB_DICDI FNIP repeat-containing protein cig... | 144 | 0.21 | 38.1 | 26 | 48 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 98 | O60346 | 1717 | PHLP1_HUMAN PH domain leucine-rich repeat-con... | 199 | 0.23 | 38.1 | 28 | 45 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004722; F:protein serine/threonine phosphatase activity; TAS:Reactome. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:Reactome. | 99 | Q29393 | 360 | PGS2_CANFA Decorin OS=Canis familiaris (Dog) ... | 251 | 0.25 | 37.7 | 25 | 40 | GO:0005578; C:proteinaceous extracellular matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 100 | A0JM56 | 1502 | LRRC9_XENTR Leucine-rich repeat-containing pr... | 76 | 8.8 | 33.1 | 28 | 54 | | | | | | | | | | | | | | | | | | | | | | 101 | P70389 | 603 | ALS_MOUSE Insulin-like growth factor-binding ... | 162 | 0.36 | 37.4 | 27 | 47 | GO:0005615; C:extracellular space; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0007155; P:cell adhesion; IEA:UniProtKB-KW. | 102 | Q8IUZ0 | 686 | LRC49_HUMAN Leucine-rich repeat-containing pr... | 204 | 5.4 | 33.5 | 23 | 43 | GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW. | | | | | | | | | | | | | | | | | | | | | 103 | Q62192 | 661 | CD180_MOUSE CD180 antigen OS=Mus musculus (Mo... | 197 | 0.35 | 37.4 | 26 | 43 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004872; F:receptor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW. | 104 | O00206 | 839 | TLR4_HUMAN Toll-like receptor 4 OS=Homo sapie... | 143 | 0.36 | 37.4 | 31 | 52 | GO:0009897; C:external side of plasma membrane; IDA:BHF-UCL.::GO:0005887; C:integral to plasma membrane; IDA:UniProtKB.::GO:0046696; C:lipopolysaccharide receptor complex; IDA:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IDA:UniProtKB. | | | | | | | | | | GO:0001530; F:lipopolysaccharide binding; NAS:UniProtKB.::GO:0001875; F:lipopolysaccharide receptor activity; IDA:UniProtKB.::GO:0004888; F:transmembrane signaling receptor activity; NAS:UniProtKB. | | | | | | | | | | GO:0000187; P:activation of MAPK activity; ISS:BHF-UCL.::GO:0071260; P:cellular response to mechanical stimulus; IEP:UniProtKB.::GO:0050829; P:defense response to Gram-negative bacterium; IC:BHF-UCL.::GO:0016046; P:detection of fungus; NAS:UniProtKB.::GO:0032497; P:detection of lipopolysaccharide; IDA:UniProtKB.::GO:0007252; P:I-kappaB phosphorylation; IDA:BHF-UCL.::GO:0045087; P:innate immune response; TAS:BHF-UCL.::GO:0060729; P:intestinal epithelial structure maintenance; ISS:BHF-UCL.::GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.::GO:0002756; P:MyD88-independent toll-like receptor signaling pathway; TAS:Reactome.::GO:0070373; P:negative regulation of ERK1 and ERK2 cascade; ISS:BHF-UCL.::GO:0032689; P:negative regulation of interferon-gamma production; ISS:BHF-UCL.::GO:0032700; P:negative regulation of interleukin-17 production; ISS:BHF-UCL.::GO:0032707; P:negative regulation of interleukin-23 production; ISS:BHF-UCL.::GO:0032715; P:negative regulation of interleukin-6 production; ISS:BHF-UCL.::GO:0045671; P:negative regulation of osteoclast differentiation; NAS:UniProtKB.::GO:0032720; P:negative regulation of tumor necrosis factor production; ISS:BHF-UCL.::GO:0032722; P:positive regulation of chemokine production; IDA:BHF-UCL.::GO:0050729; P:positive regulation of inflammatory response; IC:BHF-UCL.::GO:0032727; P:positive regulation of interferon-alpha production; ISS:BHF-UCL.::GO:0032728; P:positive regulation of interferon-beta production; ISS:BHF-UCL.::GO:0032729; P:positive regulation of interferon-gamma production; ISS:BHF-UCL.::GO:0032732; P:positive regulation of interleukin-1 production; ISS:BHF-UCL.::GO:0032733; P:positive regulation of interleukin-10 production; ISS:BHF-UCL.::GO:0045084; P:positive regulation of interleukin-12 biosynthetic process; IDA:UniProtKB.::GO:0032735; P:positive regulation of interleukin-12 production; ISS:BHF-UCL.::GO:0032755; P:positive regulation of interleukin-6 production; IDA:BHF-UCL.::GO:0045416; P:positive regulation of interleukin-8 biosynthetic process; IDA:UniProtKB.::GO:0032757; P:positive regulation of interleukin-8 production; IDA:BHF-UCL.::GO:0042346; P:positive regulation of NF-kappaB import into nucleus; IDA:BHF-UCL.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IDA:MGI.::GO:0051770; P:positive regulation of nitric-oxide synthase biosynthetic process; ISS:BHF-UCL.::GO:0010572; P:positive regulation of platelet activation; ISS:BHF-UCL.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:BHF-UCL.::GO:0042535; P:positive regulation of tumor necrosis factor biosynthetic process; IDA:UniProtKB.::GO:0032760; P:positive regulation of tumor necrosis factor production; ISS:BHF-UCL.::GO:0042088; P:T-helper 1 type immune response; NAS:UniProtKB.::GO:0008063; P:Toll signaling pathway; TAS:Reactome.::GO:0034130; P:toll-like receptor 1 signaling pathway; TAS:Reactome.::GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.::GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome. | 105 | Q9BXN1 | 380 | ASPN_HUMAN Asporin OS=Homo sapiens (Human). G... | 148 | 0.37 | 37 | 30 | 47 | GO:0005578; C:proteinaceous extracellular matrix; IDA:UniProtKB. | | | | | | | | | | GO:0005509; F:calcium ion binding; IDA:UniProtKB. | | | | | | | | | | GO:0030282; P:bone mineralization; IDA:UniProtKB.::GO:0070171; P:negative regulation of tooth mineralization; ISS:UniProtKB.::GO:0030512; P:negative regulation of transforming growth factor beta receptor signaling pathway; IDA:UniProtKB. | 106 | Q90944 | 316 | EPYC_CHICK Epiphycan OS=Gallus gallus (Chicke... | 159 | 0.38 | 37 | 23 | 48 | GO:0005578; C:proteinaceous extracellular matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 107 | Q9TTN0 | 839 | TLR4_PANPA Toll-like receptor 4 OS=Pan panisc... | 143 | 0.38 | 37.4 | 31 | 52 | GO:0005622; C:intracellular; IEA:InterPro.::GO:0046696; C:lipopolysaccharide receptor complex; ISS:UniProtKB. | | | | | | | | | | GO:0001875; F:lipopolysaccharide receptor activity; ISS:UniProtKB.::GO:0004888; F:transmembrane signaling receptor activity; IEA:InterPro. | | | | | | | | | | GO:0032497; P:detection of lipopolysaccharide; ISS:UniProtKB.::GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW.::GO:0042116; P:macrophage activation; ISS:UniProtKB. | 108 | Q9XSD9 | 360 | PGS2_PIG Decorin OS=Sus scrofa (Pig). GN=DCN ... | 251 | 0.41 | 37 | 24 | 40 | GO:0005578; C:proteinaceous extracellular matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 109 | Q13045 | 1269 | FLII_HUMAN Protein flightless-1 homolog OS=Ho... | 220 | 0.43 | 37.4 | 29 | 42 | GO:0005813; C:centrosome; IDA:HPA.::GO:0005634; C:nucleus; IDA:HPA. | | | | | | | | | | GO:0003779; F:actin binding; TAS:ProtInc. | | | | | | | | | | GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0006936; P:muscle contraction; TAS:ProtInc.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 110 | P18009 | 574 | IPA4_SHIFL Probable E3 ubiquitin-protein liga... | 188 | 0.45 | 37 | 30 | 45 | GO:0030430; C:host cell cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009405; P:pathogenesis; IEA:UniProtKB-KW. | 111 | P59383 | 733 | LRRN4_MOUSE Leucine-rich repeat neuronal prot... | 111 | 0.49 | 37 | 32 | 52 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | | | | | | | | | | | | 112 | Q9W6H0 | 294 | MIME_CHICK Mimecan OS=Gallus gallus (Chicken)... | 71 | 0.51 | 36.6 | 32 | 49 | GO:0005578; C:proteinaceous extracellular matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008083; F:growth factor activity; IEA:UniProtKB-KW. | | | | | | | | | | | 113 | Q10666 | 438 | POP1_CAEEL Protein pop-1 OS=Caenorhabditis el... | 79 | 0.52 | 36.6 | 29 | 51 | GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005667; C:transcription factor complex; IBA:RefGenome. | | | | | | | | | | GO:0008013; F:beta-catenin binding; IPI:WormBase.::GO:0035035; F:histone acetyltransferase binding; IPI:WormBase.::GO:0042826; F:histone deacetylase binding; IPI:UniProtKB.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0043565; F:sequence-specific DNA binding; IDA:WormBase.::GO:0008134; F:transcription factor binding; IPI:UniProtKB.::GO:0044212; F:transcription regulatory region DNA binding; IBA:RefGenome. | | | | | | | | | | GO:0006915; P:apoptotic process; IMP:WormBase.::GO:0008356; P:asymmetric cell division; IMP:UniProtKB.::GO:0060070; P:canonical Wnt receptor signaling pathway; IBA:RefGenome.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0009880; P:embryonic pattern specification; IMP:WormBase.::GO:0001703; P:gastrulation with mouth forming first; IMP:WormBase.::GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0007500; P:mesodermal cell fate determination; IMP:WormBase.::GO:0007052; P:mitotic spindle organization; IMP:WormBase.::GO:0002009; P:morphogenesis of an epithelium; IMP:WormBase.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0040027; P:negative regulation of vulval development; IMP:WormBase.::GO:0043282; P:pharyngeal muscle development; IMP:WormBase.::GO:0010085; P:polarity specification of proximal/distal axis; IGI:WormBase.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:WormBase.::GO:0040026; P:positive regulation of vulval development; IMP:WormBase.::GO:0009786; P:regulation of asymmetric cell division; IGI:WormBase.::GO:0042659; P:regulation of cell fate specification; IGI:WormBase.::GO:0016246; P:RNA interference; IMP:WormBase. | 114 | Q9BXR5 | 811 | TLR10_HUMAN Toll-like receptor 10 OS=Homo sap... | 169 | 1 | 35.8 | 25 | 40 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005622; C:intracellular; IEA:InterPro.::GO:0005886; C:plasma membrane; TAS:Reactome. | | | | | | | | | | GO:0004888; F:transmembrane signaling receptor activity; TAS:UniProtKB. | | | | | | | | | | GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.::GO:0045087; P:innate immune response; TAS:Reactome.::GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome. | 115 | Q4G017 | 1502 | NISCH_RAT Nischarin OS=Rattus norvegicus (Rat... | 63 | 0.53 | 37 | 37 | 65 | GO:0005769; C:early endosome; IEA:UniProtKB-SubCell.::GO:0005624; C:membrane fraction; IDA:RGD.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0055037; C:recycling endosome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008227; F:G-protein coupled amine receptor activity; IDA:RGD.::GO:0035091; F:phosphatidylinositol binding; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0006006; P:glucose metabolic process; IMP:RGD.::GO:0048243; P:norepinephrine secretion; IMP:RGD.::GO:0008217; P:regulation of blood pressure; IMP:RGD.::GO:0032228; P:regulation of synaptic transmission, GABAergic; IMP:RGD. | 116 | B3Y613 | 784 | TLR2_PANTR Toll-like receptor 2 OS=Pan troglo... | 229 | 0.54 | 37 | 28 | 46 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0004888; F:transmembrane signaling receptor activity; IEA:InterPro. | | | | | | | | | | GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW. | 117 | B3Y614 | 784 | TLR2_PANPA Toll-like receptor 2 OS=Pan panisc... | 170 | 4.2 | 33.9 | 29 | 45 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0004888; F:transmembrane signaling receptor activity; IEA:InterPro. | | | | | | | | | | GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW. | 118 | Q704V6 | 793 | TLR6_BOVIN Toll-like receptor 6 OS=Bos taurus... | 62 | 6.9 | 33.1 | 39 | 53 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0030670; C:phagocytic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004888; F:transmembrane signaling receptor activity; IEA:InterPro. | | | | | | | | | | GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW. | 119 | Q86VH4 | 590 | LRRT4_HUMAN Leucine-rich repeat transmembrane... | 138 | 0.56 | 36.6 | 29 | 45 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | | | | | | | | | | | | 120 | Q689D1 | 785 | TLR2_CANFA Toll-like receptor 2 OS=Canis fami... | 112 | 0.58 | 36.6 | 33 | 49 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004888; F:transmembrane signaling receptor activity; IEA:InterPro. | | | | | | | | | | GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW. | 121 | P58874 | 321 | OPT_BOVIN Opticin OS=Bos taurus (Bovine). GN=... | 163 | 0.59 | 36.2 | 29 | 47 | GO:0005578; C:proteinaceous extracellular matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | |