rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
61 | Q2V897 | 784 | TLR2_BOSTR Toll-like receptor 2 OS=Boselaphus... | 112 | 8.2 | 33.1 | 23 | 46 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0004888; F:transmembrane signaling receptor activity; IEA:InterPro. | | | | | | | | | | GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW. | 62 | B2LT64 | 784 | TLR2_GIRCA Toll-like receptor 2 OS=Giraffa ca... | 112 | 6.6 | 33.5 | 23 | 46 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0004888; F:transmembrane signaling receptor activity; IEA:InterPro. | | | | | | | | | | GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW. | 63 | Q9Y2I1 | 1504 | NISCH_HUMAN Nischarin OS=Homo sapiens (Human)... | 183 | 0.039 | 40.8 | 27 | 48 | GO:0005829; C:cytosol; IDA:BHF-UCL.::GO:0005769; C:early endosome; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IDA:BHF-UCL.::GO:0055037; C:recycling endosome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0035091; F:phosphatidylinositol binding; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW. | 64 | Q6T752 | 784 | TLR2_HORSE Toll-like receptor 2 OS=Equus caba... | 282 | 0.039 | 40.4 | 28 | 46 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0004888; F:transmembrane signaling receptor activity; IEA:InterPro. | | | | | | | | | | GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW. | 65 | Q9BGP6 | 581 | LRRT3_MACFA Leucine-rich repeat transmembrane... | 144 | 0.04 | 40.4 | 31 | 46 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | | | | | | | | | | | | 66 | Q86VH5 | 581 | LRRT3_HUMAN Leucine-rich repeat transmembrane... | 144 | 0.04 | 40.4 | 31 | 46 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | | | | | | | | | | | | 67 | Q8BZ81 | 582 | LRRT3_MOUSE Leucine-rich repeat transmembrane... | 144 | 0.04 | 40.4 | 31 | 46 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | | | | | | | | | | | | 68 | Q5S006 | 2527 | LRRK2_MOUSE Leucine-rich repeat serine/threon... | 189 | 0.04 | 40.8 | 28 | 48 | GO:0045121; C:membrane raft; IDA:MGI.::GO:0005886; C:plasma membrane; IDA:MGI.::GO:0008021; C:synaptic vesicle; IDA:MGI.::GO:0005802; C:trans-Golgi network; IDA:MGI. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0017048; F:Rho GTPase binding; IPI:BHF-UCL. | | | | | | | | | | GO:0010508; P:positive regulation of autophagy; IMP:BHF-UCL.::GO:0032436; P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process; IMP:BHF-UCL.::GO:0035564; P:regulation of kidney size; IMP:BHF-UCL.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 69 | D0ZVG2 | 700 | SSPH1_SALT1 E3 ubiquitin-protein ligase sspH1... | 169 | 0.64 | 36.6 | 26 | 50 | GO:0030430; C:host cell cytoplasm; IEA:UniProtKB-SubCell.::GO:0042025; C:host cell nucleus; IDA:UniProtKB. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB. | | | | | | | | | | GO:0009405; P:pathogenesis; TAS:UniProtKB.::GO:0030254; P:protein secretion by the type III secretion system; IDA:UniProtKB. | 70 | B2LT62 | 784 | TLR2_CAPIB Toll-like receptor 2 OS=Capra ibex... | 75 | 6.9 | 33.1 | 39 | 56 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0004888; F:transmembrane signaling receptor activity; IEA:InterPro. | | | | | | | | | | GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW. | 71 | O43155 | 660 | FLRT2_HUMAN Leucine-rich repeat transmembrane... | 147 | 0.052 | 40 | 26 | 49 | GO:0005887; C:integral to plasma membrane; NAS:UniProtKB.::GO:0005578; C:proteinaceous extracellular matrix; NAS:UniProtKB. | | | | | | | | | | GO:0030674; F:protein binding, bridging; NAS:UniProtKB.::GO:0005057; F:receptor signaling protein activity; NAS:UniProtKB. | | | | | | | | | | GO:0007155; P:cell adhesion; IEA:UniProtKB-KW. | 72 | Q4R747 | 321 | LRC46_MACFA Leucine-rich repeat-containing pr... | 172 | 5.2 | 33.5 | 26 | 40 | | | | | | | | | | | | | | | | | | | | | | 73 | Q80TM9 | 1593 | NISCH_MOUSE Nischarin OS=Mus musculus (Mouse)... | 160 | 4 | 34.3 | 26 | 44 | GO:0005829; C:cytosol; IDA:MGI.::GO:0005769; C:early endosome; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0055037; C:recycling endosome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005178; F:integrin binding; IDA:MGI.::GO:0035091; F:phosphatidylinositol binding; IEA:InterPro. | | | | | | | | | | GO:0030036; P:actin cytoskeleton organization; IDA:MGI.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0030336; P:negative regulation of cell migration; IDA:MGI.::GO:0016601; P:Rac protein signal transduction; IDA:MGI. | 74 | Q0ZUL9 | 789 | TLR6_DASNO Toll-like receptor 6 OS=Dasypus no... | 94 | 3.2 | 34.3 | 35 | 54 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0030670; C:phagocytic vesicle membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004888; F:transmembrane signaling receptor activity; IEA:InterPro. | | | | | | | | | | GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW. | 75 | Q9EPW9 | 795 | TLR6_MOUSE Toll-like receptor 6 OS=Mus muscul... | 74 | 1.7 | 35 | 38 | 50 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0030670; C:phagocytic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0035355; C:Toll-like receptor 2-Toll-like receptor 6 protein complex; IDA:MGI. | | | | | | | | | | GO:0042498; F:diacyl lipopeptide binding; IDA:MGI.::GO:0046982; F:protein heterodimerization activity; IPI:MGI.::GO:0004888; F:transmembrane signaling receptor activity; IEA:InterPro. | | | | | | | | | | GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW.::GO:0045084; P:positive regulation of interleukin-12 biosynthetic process; NAS:UniProtKB.::GO:0045410; P:positive regulation of interleukin-6 biosynthetic process; ISS:UniProtKB.::GO:0042088; P:T-helper 1 type immune response; IC:UniProtKB. | 76 | Q9R1F8 | 784 | TLR2_CRIGR Toll-like receptor 2 OS=Cricetulus... | 183 | 0.067 | 39.7 | 30 | 50 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0004888; F:transmembrane signaling receptor activity; IEA:InterPro. | | | | | | | | | | GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW. | 77 | Q6GPJ8 | 807 | CEP97_XENLA Centrosomal protein of 97 kDa OS=... | 145 | 0.44 | 37.4 | 28 | 48 | GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 78 | O60602 | 858 | TLR5_HUMAN Toll-like receptor 5 OS=Homo sapie... | 273 | 0.074 | 39.7 | 26 | 48 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005622; C:intracellular; IEA:InterPro.::GO:0005886; C:plasma membrane; TAS:Reactome. | | | | | | | | | | GO:0005149; F:interleukin-1 receptor binding; IPI:UniProtKB.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0071260; P:cellular response to mechanical stimulus; IEP:UniProtKB.::GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.::GO:0045087; P:innate immune response; TAS:Reactome.::GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.::GO:0032757; P:positive regulation of interleukin-8 production; IDA:BHF-UCL.::GO:0034123; P:positive regulation of toll-like receptor signaling pathway; IDA:BHF-UCL. | 79 | Q5S007 | 2527 | LRRK2_HUMAN Leucine-rich repeat serine/threon... | 255 | 0.075 | 39.7 | 29 | 45 | GO:0032473; C:external side of mitochondrial outer membrane; IDA:UniProtKB.::GO:0005624; C:membrane fraction; IDA:UniProtKB.::GO:0043005; C:neuron projection; IDA:BHF-UCL.::GO:0043025; C:neuronal cell body; IDA:BHF-UCL. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005525; F:GTP binding; IDA:UniProtKB.::GO:0034211; F:GTP-dependent protein kinase activity; IMP:UniProtKB.::GO:0005096; F:GTPase activator activity; IDA:UniProtKB.::GO:0003924; F:GTPase activity; IDA:BHF-UCL.::GO:0004708; F:MAP kinase kinase activity; IDA:BHF-UCL.::GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.::GO:0017048; F:Rho GTPase binding; IPI:BHF-UCL.::GO:0015631; F:tubulin binding; IDA:BHF-UCL. | | | | | | | | | | GO:0000186; P:activation of MAPKK activity; IDA:BHF-UCL.::GO:0008340; P:determination of adult lifespan; IMP:BHF-UCL.::GO:0035640; P:exploration behavior; IMP:BHF-UCL.::GO:0048312; P:intracellular distribution of mitochondria; IMP:BHF-UCL.::GO:2000173; P:negative regulation of branching morphogenesis of a nerve; IMP:BHF-UCL.::GO:0061002; P:negative regulation of dendritic spine morphogenesis; IMP:BHF-UCL.::GO:0007406; P:negative regulation of neuroblast proliferation; IMP:BHF-UCL.::GO:0014043; P:negative regulation of neuron maturation; IMP:BHF-UCL.::GO:0007528; P:neuromuscular junction development; IMP:BHF-UCL.::GO:0070997; P:neuron death; IMP:BHF-UCL.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:BHF-UCL.::GO:0018107; P:peptidyl-threonine phosphorylation; IDA:BHF-UCL.::GO:0010508; P:positive regulation of autophagy; ISS:BHF-UCL.::GO:0060161; P:positive regulation of dopamine receptor signaling pathway; IMP:BHF-UCL.::GO:0043068; P:positive regulation of programmed cell death; IDA:UniProtKB.::GO:0032436; P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process; ISS:BHF-UCL.::GO:0001934; P:positive regulation of protein phosphorylation; IMP:BHF-UCL.::GO:0031398; P:positive regulation of protein ubiquitination; IDA:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:0035564; P:regulation of kidney size; ISS:BHF-UCL.::GO:0040012; P:regulation of locomotion; IMP:BHF-UCL.::GO:0042391; P:regulation of membrane potential; IMP:BHF-UCL.::GO:0006979; P:response to oxidative stress; IMP:BHF-UCL.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0022028; P:tangential migration from the subventricular zone to the olfactory bulb; IMP:BHF-UCL. | 80 | Q91YK0 | 686 | LRC49_MOUSE Leucine-rich repeat-containing pr... | 179 | 2.2 | 34.7 | 24 | 46 | GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW. | | | | | | | | | | | | | | | | | | | | | 81 | B5T267 | 784 | TLR2_BOSIN Toll-like receptor 2 OS=Bos indicu... | 112 | 8.5 | 33.1 | 23 | 46 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0004888; F:transmembrane signaling receptor activity; IEA:InterPro. | | | | | | | | | | GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW. | 82 | Q83RJ4 | 571 | IPA3_SHIFL E3 ubiquitin-protein ligase ipaH3 ... | 107 | 0.16 | 38.5 | 34 | 55 | GO:0030430; C:host cell cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009405; P:pathogenesis; IEA:UniProtKB-KW. | 83 | Q9Z1P4 | 907 | LGR5_MOUSE Leucine-rich repeat-containing G-p... | 280 | 0.089 | 39.3 | 26 | 44 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016500; F:protein-hormone receptor activity; IEA:InterPro. | | | | | | | | | | GO:0048839; P:inner ear development; IDA:MGI. | 84 | Q9Z2H4 | 951 | LGR4_RAT Leucine-rich repeat-containing G-pro... | 340 | 0.09 | 39.3 | 25 | 41 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016500; F:protein-hormone receptor activity; IEA:InterPro. | | | | | | | | | | | 85 | Q6AXZ2 | 323 | LRC46_RAT Leucine-rich repeat-containing prot... | 71 | 3 | 33.9 | 31 | 55 | | | | | | | | | | | | | | | | | | | | | | 86 | O77742 | 422 | OMD_BOVIN Osteomodulin OS=Bos taurus (Bovine)... | 359 | 0.1 | 38.9 | 24 | 38 | GO:0005578; C:proteinaceous extracellular matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0007155; P:cell adhesion; IEA:UniProtKB-KW. | 87 | Q8C031 | 640 | LRC4C_MOUSE Leucine-rich repeat-containing pr... | 145 | 0.1 | 39.3 | 34 | 49 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0050770; P:regulation of axonogenesis; ISS:UniProtKB. | 88 | Q9HCJ2 | 640 | LRC4C_HUMAN Leucine-rich repeat-containing pr... | 145 | 0.11 | 38.9 | 34 | 49 | GO:0016021; C:integral to membrane; NAS:UniProtKB. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0050770; P:regulation of axonogenesis; IDA:UniProtKB. | 89 | Q6ZRR7 | 1453 | LRRC9_HUMAN Leucine-rich repeat-containing pr... | 141 | 0.12 | 39.3 | 27 | 50 | | | | | | | | | | | | | | | | | | | | | | 90 | P17778 | 409 | YOPM_YERPE Outer membrane protein yopM OS=Yer... | 325 | 0.12 | 38.5 | 25 | 44 | GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.::GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | | 91 | Q7SXW3 | 601 | LRC40_DANRE Leucine-rich repeat-containing pr... | 273 | 0.14 | 38.5 | 28 | 45 | | | | | | | | | | | | | | | | | | | | | |