rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | P32361 | 1115 | IRE1_YEAST Serine/threonine-protein kinase/en... | 342 | 7e-50 | 196 | 38 | 57 | GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005634; C:nucleus; IDA:SGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016891; F:endoribonuclease activity, producing 5'-phosphomonoesters; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0042803; F:protein homodimerization activity; IDA:SGD.::GO:0004674; F:protein serine/threonine kinase activity; IDA:SGD.::GO:0051082; F:unfolded protein binding; IMP:SGD. | | | | | | | | | | GO:0030968; P:endoplasmic reticulum unfolded protein response; IMP:SGD.::GO:0031505; P:fungal-type cell wall organization; IMP:SGD.::GO:0006020; P:inositol metabolic process; IMP:SGD.::GO:0006397; P:mRNA processing; IEA:InterPro.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 2 | O94537 | 1072 | PPK4_SCHPO Serine/threonine-protein kinase pp... | 412 | 0.00000000000006 | 80.9 | 25 | 41 | GO:0005789; C:endoplasmic reticulum membrane; ISS:PomBase.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016891; F:endoribonuclease activity, producing 5'-phosphomonoesters; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; ISS:PomBase. | | | | | | | | | | GO:0006916; P:anti-apoptosis; IGI:PomBase.::GO:0030968; P:endoplasmic reticulum unfolded protein response; ISS:PomBase.::GO:0006397; P:mRNA processing; IEA:InterPro. | 3 | Q9Z2E3 | 911 | ERN2_MOUSE Serine/threonine-protein kinase/en... | 224 | 0.0000000002 | 68.9 | 25 | 46 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0016891; F:endoribonuclease activity, producing 5'-phosphomonoesters; IEA:InterPro.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0006987; P:activation of signaling protein activity involved in unfolded protein response; ISS:UniProtKB.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007050; P:cell cycle arrest; IDA:UniProtKB.::GO:0006917; P:induction of apoptosis; IDA:UniProtKB.::GO:0006397; P:mRNA processing; IEA:InterPro.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 4 | Q09499 | 967 | IRE1_CAEEL Serine/threonine-protein kinase/en... | 179 | 0.000000006 | 64.3 | 30 | 47 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016891; F:endoribonuclease activity, producing 5'-phosphomonoesters; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0030968; P:endoplasmic reticulum unfolded protein response; IMP:WormBase.::GO:0006397; P:mRNA processing; IEA:InterPro.::GO:0002119; P:nematode larval development; IGI:WormBase.::GO:0040017; P:positive regulation of locomotion; IMP:WormBase.::GO:0000003; P:reproduction; IMP:WormBase. | 5 | Q76MJ5 | 926 | ERN2_HUMAN Serine/threonine-protein kinase/en... | 227 | 0.00000000002 | 72 | 26 | 46 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0016891; F:endoribonuclease activity, producing 5'-phosphomonoesters; IEA:InterPro.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0006917; P:induction of apoptosis; IMP:UniProtKB.::GO:0006397; P:mRNA processing; IEA:InterPro.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IMP:UniProtKB.::GO:0016075; P:rRNA catabolic process; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 6 | Q9EQY0 | 977 | ERN1_MOUSE Serine/threonine-protein kinase/en... | 234 | 0.000000000005 | 74.3 | 24 | 50 | GO:0005637; C:nuclear inner membrane; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0016891; F:endoribonuclease activity, producing 5'-phosphomonoesters; IEA:InterPro.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0006987; P:activation of signaling protein activity involved in unfolded protein response; ISS:UniProtKB.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007050; P:cell cycle arrest; IDA:UniProtKB.::GO:0006917; P:induction of apoptosis; IDA:UniProtKB.::GO:0006397; P:mRNA processing; IEA:InterPro.::GO:0046777; P:protein autophosphorylation; IDA:MGI.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 7 | O75460 | 977 | ERN1_HUMAN Serine/threonine-protein kinase/en... | 232 | 0.000000000003 | 75.1 | 25 | 50 | GO:0030176; C:integral to endoplasmic reticulum membrane; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0016891; F:endoribonuclease activity, producing 5'-phosphomonoesters; IEA:InterPro.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB. | | | | | | | | | | GO:0006987; P:activation of signaling protein activity involved in unfolded protein response; IDA:UniProtKB.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007050; P:cell cycle arrest; ISS:UniProtKB.::GO:0006917; P:induction of apoptosis; ISS:UniProtKB.::GO:0006397; P:mRNA processing; IEA:InterPro.::GO:1900103; P:positive regulation of endoplasmic reticulum unfolded protein response; IMP:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 8 | Q55GJ2 | 984 | IREA_DICDI Probable serine/threonine-protein ... | 208 | 2.9 | 35.8 | 21 | 42 | GO:0005789; C:endoplasmic reticulum membrane; ISS:dictyBase.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005635; C:nuclear envelope; ISS:dictyBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016891; F:endoribonuclease activity, producing 5'-phosphomonoesters; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; ISS:dictyBase. | | | | | | | | | | GO:0006020; P:inositol metabolic process; ISS:dictyBase.::GO:0006397; P:mRNA processing; IEA:InterPro. | 9 | Q55DJ8 | 1444 | IRLC_DICDI Probable serine/threonine-protein ... | 347 | 5e-33 | 142 | 31 | 47 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016891; F:endoribonuclease activity, producing 5'-phosphomonoesters; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006397; P:mRNA processing; IEA:InterPro. | 10 | Q557G1 | 1448 | IRLB_DICDI Probable serine/threonine-protein ... | 454 | 5e-33 | 142 | 28 | 44 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016891; F:endoribonuclease activity, producing 5'-phosphomonoesters; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006397; P:mRNA processing; IEA:InterPro. | 11 | Q54IE8 | 1350 | IRLE_DICDI Probable serine/threonine-protein ... | 339 | 7e-33 | 142 | 32 | 48 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016891; F:endoribonuclease activity, producing 5'-phosphomonoesters; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006397; P:mRNA processing; IEA:InterPro. | 12 | Q55DJ9 | 1505 | IRLD_DICDI Probable serine/threonine-protein ... | 348 | 2e-32 | 140 | 29 | 46 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016891; F:endoribonuclease activity, producing 5'-phosphomonoesters; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006397; P:mRNA processing; IEA:InterPro. | 13 | Q556Q3 | 1400 | IRLF_DICDI Probable serine/threonine-protein ... | 434 | 4e-32 | 140 | 28 | 45 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016891; F:endoribonuclease activity, producing 5'-phosphomonoesters; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006397; P:mRNA processing; IEA:InterPro. | 14 | Q559A2 | 1431 | IRLA_DICDI Probable serine/threonine-protein ... | 351 | 2e-30 | 134 | 30 | 46 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016891; F:endoribonuclease activity, producing 5'-phosphomonoesters; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006397; P:mRNA processing; IEA:InterPro. | 15 | Q54MH0 | 749 | FHKD_DICDI Probable serine/threonine-protein ... | 284 | 9e-16 | 86.3 | 29 | 45 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0000077; P:DNA damage checkpoint; ISS:dictyBase. | 16 | Q00771 | 414 | KCC1_EMENI Calcium/calmodulin-dependent prote... | 339 | 0.00000000000003 | 80.1 | 26 | 42 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; IEA:EC. | | | | | | | | | | | 17 | Q5UQ78 | 450 | YR517_MIMIV Putative serine/threonine-protein... | 342 | 0.00000000000004 | 80.1 | 27 | 43 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 18 | Q11179 | 470 | YPC2_CAEEL Putative serine/threonine-protein ... | 358 | 0.00000000000005 | 79.7 | 23 | 40 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC. | | | | | | | | | | GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040007; P:growth; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase. | 19 | P22517 | 447 | KCC2_YEAST Calcium/calmodulin-dependent prote... | 386 | 0.00000000000009 | 79 | 25 | 40 | GO:0005737; C:cytoplasm; IDA:SGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; IDA:SGD. | | | | | | | | | | GO:0007165; P:signal transduction; NAS:SGD. | 20 | Q8TD08 | 544 | MK15_HUMAN Mitogen-activated protein kinase 1... | 356 | 0.0000000000002 | 78.2 | 25 | 40 | GO:0005576; C:extracellular region; NAS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IDA:UniProtKB.::GO:0017124; F:SH3 domain binding; NAS:UniProtKB. | | | | | | | | | | GO:0046777; P:protein autophosphorylation; IDA:UniProtKB. | 21 | Q95YH0 | 380 | CDK8_DICDI Probable cyclin-dependent kinase 8... | 380 | 0.0000000000002 | 77 | 24 | 39 | GO:0005829; C:cytosol; IDA:dictyBase.::GO:0016591; C:DNA-directed RNA polymerase II, holoenzyme; ISS:dictyBase.::GO:0005615; C:extracellular space; IDA:dictyBase. | | | | | | | | | | GO:0005524; F:ATP binding; IC:dictyBase.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0016538; F:cyclin-dependent protein kinase regulator activity; ISS:dictyBase.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IDA:dictyBase. | | | | | | | | | | GO:0031152; P:aggregation involved in sorocarp development; IMP:dictyBase.::GO:0043689; P:cell-cell adhesion involved in flocculation; IMP:UniProtKB.::GO:0000082; P:G1/S transition of mitotic cell cycle; ISS:UniProtKB.::GO:0070816; P:phosphorylation of RNA polymerase II C-terminal domain; IDA:dictyBase.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 22 | Q9LQQ9 | 363 | MPK13_ARATH Mitogen-activated protein kinase ... | 354 | 0.0000000000006 | 75.5 | 26 | 38 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | | 23 | Q54VI1 | 712 | FHKE_DICDI Probable serine/threonine-protein ... | 337 | 0.0000000000007 | 76.6 | 27 | 42 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:dictyBase. | | | | | | | | | | GO:0000077; P:DNA damage checkpoint; ISS:dictyBase. | 24 | P54666 | 311 | CC2H3_TRYBB Cell division control protein 2 h... | 350 | 0.0000000000008 | 74.3 | 25 | 40 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC. | | | | | | | | | | | 25 | Q4V3C8 | 486 | PDPK2_ARATH 3-phosphoinositide-dependent prot... | 341 | 0.0000000000009 | 75.9 | 26 | 42 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IDA:TAIR. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 26 | Q9XF67 | 491 | PDPK1_ARATH 3-phosphoinositide-dependent prot... | 341 | 0.000000000001 | 75.5 | 26 | 42 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004676; F:3-phosphoinositide-dependent protein kinase activity; IGI:TAIR.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0070300; F:phosphatidic acid binding; IDA:UniProtKB.::GO:0035091; F:phosphatidylinositol binding; IDA:TAIR.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0045860; P:positive regulation of protein kinase activity; IDA:TAIR.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB. | 27 | Q501V0 | 422 | KPSH1_DANRE Serine/threonine-protein kinase H... | 330 | 0.000000000001 | 74.7 | 25 | 42 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 28 | Q8ICR0 | 509 | CDPK2_PLAF7 Calcium-dependent protein kinase ... | 355 | 0.000000000002 | 75.1 | 27 | 43 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004683; F:calmodulin-dependent protein kinase activity; TAS:GeneDB_Pfalciparum. | | | | | | | | | | | 29 | P25848 | 1307 | PHY1_CERPU Light-sensor Protein kinase OS=Cer... | 347 | 0.000000000002 | 75.9 | 29 | 42 | GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008020; F:G-protein coupled photoreceptor activity; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0000155; F:two-component sensor activity; IEA:InterPro. | | | | | | | | | | GO:0018298; P:protein-chromophore linkage; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 30 | O15865 | 513 | CDPK2_PLAFK Calcium-dependent protein kinase ... | 355 | 0.000000000002 | 74.7 | 27 | 43 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 31 | P21965 | 375 | MCK1_YEAST Protein kinase MCK1 OS=Saccharomyc... | 365 | 0.000000000003 | 73.6 | 28 | 42 | GO:0005625; C:soluble fraction; IDA:SGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004712; F:protein serine/threonine/tyrosine kinase activity; IDA:SGD. | | | | | | | | | | GO:0030437; P:ascospore formation; IMP:SGD.::GO:0006303; P:double-strand break repair via nonhomologous end joining; IMP:SGD.::GO:0007126; P:meiosis; IMP:SGD.::GO:0000070; P:mitotic sister chromatid segregation; IGI:SGD. |