| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | Q12514 | 560 | NOT5_YEAST General negative regulator of tran... | 698 | 2e-57 | 209 | 28 | 45 | GO:0030015; C:CCR4-NOT core complex; IPI:SGD.::GO:0005737; C:cytoplasm; IDA:SGD.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0031087; P:deadenylation-independent decapping of nuclear-transcribed mRNA; IMP:SGD.::GO:0000289; P:nuclear-transcribed mRNA poly(A) tail shortening; IDA:SGD.::GO:0032968; P:positive regulation of transcription elongation from RNA polymerase II promoter; IDA:SGD.::GO:0016567; P:protein ubiquitination; IMP:SGD.::GO:0006368; P:transcription elongation from RNA polymerase II promoter; IMP:SGD. | 2 | O13870 | 640 | NOT3_SCHPO General negative regulator of tran... | 237 | 2e-46 | 178 | 43 | 64 | GO:0030015; C:CCR4-NOT core complex; ISS:PomBase.::GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0000289; P:nuclear-transcribed mRNA poly(A) tail shortening; ISS:PomBase.::GO:0006357; P:regulation of transcription from RNA polymerase II promoter; ISS:PomBase.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 3 | Q8K0V4 | 751 | CNOT3_MOUSE CCR4-NOT transcription complex su... | 187 | 0.0000000000002 | 77 | 29 | 43 | GO:0000932; C:cytoplasmic mRNA processing body; IDA:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 4 | O75175 | 753 | CNOT3_HUMAN CCR4-NOT transcription complex su... | 159 | 0.0000000000003 | 77 | 30 | 45 | GO:0000932; C:cytoplasmic mRNA processing body; ISS:UniProtKB.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0000289; P:nuclear-transcribed mRNA poly(A) tail shortening; TAS:Reactome.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 5 | P06102 | 836 | NOT3_YEAST General negative regulator of tran... | 430 | 5e-33 | 139 | 31 | 49 | GO:0030015; C:CCR4-NOT core complex; IPI:SGD.::GO:0005737; C:cytoplasm; IDA:SGD.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0000289; P:nuclear-transcribed mRNA poly(A) tail shortening; IDA:SGD.::GO:0032968; P:positive regulation of transcription elongation from RNA polymerase II promoter; IDA:SGD.::GO:0016567; P:protein ubiquitination; IMP:SGD.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 6 | Q52JK6 | 603 | VIP2_NICBE Probable NOT transcription complex... | 53 | 0.028 | 41.2 | 40 | 49 | GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0015074; P:DNA integration; IMP:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 7 | Q3UFM5 | 854 | NOM1_MOUSE Nucleolar MIF4G domain-containing ... | 110 | 0.29 | 38.1 | 31 | 44 | GO:0005730; C:nucleolus; ISS:UniProtKB. | | | | | | | | | | GO:0005488; F:binding; IEA:InterPro. | | | | | | | | | | GO:0016070; P:RNA metabolic process; IEA:InterPro. | 8 | Q10711 | 883 | ECE2_BOVIN Endothelin-converting enzyme 2 OS=... | 82 | 0.92 | 36.6 | 28 | 46 | GO:0030659; C:cytoplasmic vesicle membrane; ISS:UniProtKB.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IDA:UniProtKB.::GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.::GO:0042803; F:protein homodimerization activity; TAS:UniProtKB. | | | | | | | | | | GO:0007420; P:brain development; ISS:UniProtKB.::GO:0010002; P:cardioblast differentiation; ISS:UniProtKB.::GO:0009790; P:embryo development; TAS:UniProtKB.::GO:0016486; P:peptide hormone processing; ISS:UniProtKB.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0008277; P:regulation of G-protein coupled receptor protein signaling pathway; TAS:UniProtKB.::GO:0042310; P:vasoconstriction; TAS:UniProtKB. | 9 | Q94547 | 585 | RGA_DROME Regulator of gene activity OS=Droso... | 87 | 1.4 | 35.8 | 29 | 44 | GO:0030014; C:CCR4-NOT complex; IDA:FlyBase.::GO:0005737; C:cytoplasm; IDA:FlyBase.::GO:0005634; C:nucleus; NAS:UniProtKB. | | | | | | | | | | | | | | | | | | | | GO:0007095; P:mitotic cell cycle G2/M transition DNA damage checkpoint; IGI:FlyBase.::GO:0006355; P:regulation of transcription, DNA-dependent; IMP:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IMP:UniProtKB. | 10 | O60344 | 883 | ECE2_HUMAN Endothelin-converting enzyme 2 OS=... | 82 | 3 | 34.7 | 27 | 46 | GO:0030659; C:cytoplasmic vesicle membrane; IDA:UniProtKB.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IDA:UniProtKB.::GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007420; P:brain development; ISS:UniProtKB.::GO:0010002; P:cardioblast differentiation; ISS:UniProtKB.::GO:0007267; P:cell-cell signaling; TAS:UniProtKB.::GO:0016486; P:peptide hormone processing; IDA:UniProtKB.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 11 | A8PKH2 | 1096 | EIF3A_BRUMA Eukaryotic translation initiation... | 113 | 3.4 | 34.7 | 27 | 52 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW. | | | | | | | | | | | 12 | Q9NQC7 | 956 | CYLD_HUMAN Ubiquitin carboxyl-terminal hydrol... | 244 | 4 | 34.3 | 20 | 38 | GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0031234; C:extrinsic to internal side of plasma membrane; IDA:UniProtKB.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0005840; C:ribosome; IEA:InterPro. | | | | | | | | | | GO:0070064; F:proline-rich region binding; IPI:UniProtKB.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0003735; F:structural constituent of ribosome; IEA:InterPro.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0004843; F:ubiquitin-specific protease activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IDA:UniProtKB. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006917; P:induction of apoptosis; IDA:UniProtKB.::GO:0045087; P:innate immune response; TAS:Reactome.::GO:0090090; P:negative regulation of canonical Wnt receptor signaling pathway; IMP:UniProtKB.::GO:0042347; P:negative regulation of NF-kappaB import into nucleus; IDA:UniProtKB.::GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; IDA:UniProtKB.::GO:0032480; P:negative regulation of type I interferon production; TAS:Reactome.::GO:0070423; P:nucleotide-binding oligomerization domain containing signaling pathway; TAS:Reactome.::GO:2001238; P:positive regulation of extrinsic apoptotic signaling pathway; IMP:UniProtKB.::GO:0070536; P:protein K63-linked deubiquitination; IDA:UniProtKB.::GO:0070507; P:regulation of microtubule cytoskeleton organization; IMP:UniProtKB.::GO:0007346; P:regulation of mitotic cell cycle; IMP:UniProtKB.::GO:0006412; P:translation; IEA:InterPro.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. | 13 | Q80T03 | 2850 | MUC6_MOUSE Mucin-6 OS=Mus musculus (Mouse). G... | 120 | 9.7 | 33.1 | 23 | 43 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 14 | Q14258 | 630 | TRI25_HUMAN E3 ubiquitin/ISG15 ligase TRIM25 ... | 95 | 4.6 | 34.3 | 29 | 57 | GO:0030054; C:cell junction; IDA:HPA.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IDA:HPA. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0045087; P:innate immune response; TAS:Reactome.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0032480; P:negative regulation of type I interferon production; TAS:Reactome.::GO:0009615; P:response to virus; IEA:UniProtKB-KW. | 15 | P10383 | 853 | OTU_DROME Protein ovarian tumor locus OS=Dros... | 104 | 6.7 | 33.5 | 32 | 48 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0051276; P:chromosome organization; TAS:FlyBase.::GO:0019099; P:female germ-line sex determination; NAS:FlyBase.::GO:0048134; P:germ-line cyst formation; TAS:FlyBase.::GO:0048477; P:oogenesis; TAS:FlyBase.::GO:0032877; P:positive regulation of DNA endoreduplication; IMP:FlyBase. | 16 | Q9HC84 | 5762 | MUC5B_HUMAN Mucin-5B OS=Homo sapiens (Human).... | 141 | 8.3 | 33.5 | 27 | 47 | GO:0005576; C:extracellular region; NAS:UniProtKB.::GO:0005796; C:Golgi lumen; TAS:Reactome. | | | | | | | | | | GO:0005201; F:extracellular matrix structural constituent; NAS:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0007155; P:cell adhesion; NAS:UniProtKB.::GO:0016266; P:O-glycan processing; TAS:Reactome.::GO:0043687; P:post-translational protein modification; TAS:Reactome. |
