| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | P87163 | 732 | EI2BE_CANAL Translation initiation factor eIF... | 732 | 0 | 1505 | 99 | 99 | GO:0005851; C:eukaryotic translation initiation factor 2B complex; ISS:CGD. | | | | | | | | | | GO:0016779; F:nucleotidyltransferase activity; IEA:InterPro.::GO:0003743; F:translation initiation factor activity; ISS:CGD. | | | | | | | | | | GO:0016070; P:RNA metabolic process; IEA:InterPro. | 2 | P32501 | 712 | EI2BE_YEAST Translation initiation factor eIF... | 724 | 0 | 763 | 54 | 73 | GO:0005851; C:eukaryotic translation initiation factor 2B complex; IDA:SGD.::GO:0032045; C:guanyl-nucleotide exchange factor complex; IDA:SGD. | | | | | | | | | | GO:0005085; F:guanyl-nucleotide exchange factor activity; IDA:SGD.::GO:0016779; F:nucleotidyltransferase activity; IEA:InterPro.::GO:0003743; F:translation initiation factor activity; IGI:SGD. | | | | | | | | | | GO:0006446; P:regulation of translational initiation; IDA:SGD.::GO:0016070; P:RNA metabolic process; IEA:InterPro. | 3 | P56287 | 678 | EI2BE_SCHPO Probable translation initiation f... | 704 | 0 | 545 | 43 | 62 | GO:0005829; C:cytosol; IDA:PomBase.::GO:0005851; C:eukaryotic translation initiation factor 2B complex; ISS:PomBase. | | | | | | | | | | GO:0005085; F:guanyl-nucleotide exchange factor activity; ISS:PomBase.::GO:0016779; F:nucleotidyltransferase activity; IEA:InterPro.::GO:0003743; F:translation initiation factor activity; ISS:PomBase. | | | | | | | | | | GO:0002183; P:cytoplasmic translational initiation; NAS:PomBase.::GO:0016070; P:RNA metabolic process; IEA:InterPro. | 4 | Q54RF3 | 707 | EI2BE_DICDI Translation initiation factor eIF... | 432 | 4e-110 | 356 | 43 | 63 | GO:0005851; C:eukaryotic translation initiation factor 2B complex; ISS:dictyBase.::GO:0043614; C:multi-eIF complex; ISS:dictyBase. | | | | | | | | | | GO:0005488; F:binding; IEA:InterPro.::GO:0005085; F:guanyl-nucleotide exchange factor activity; ISS:dictyBase.::GO:0016779; F:nucleotidyltransferase activity; IEA:InterPro. | | | | | | | | | | GO:0009058; P:biosynthetic process; IEA:InterPro.::GO:0016070; P:RNA metabolic process; IEA:InterPro. | 5 | Q8CHW4 | 717 | EI2BE_MOUSE Translation initiation factor eIF... | 713 | 7e-102 | 335 | 30 | 52 | GO:0005851; C:eukaryotic translation initiation factor 2B complex; ISS:UniProtKB.::GO:0005634; C:nucleus; IDA:MGI. | | | | | | | | | | GO:0016740; F:transferase activity; IEA:InterPro.::GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0014002; P:astrocyte development; ISS:UniProtKB.::GO:0042552; P:myelination; ISS:UniProtKB.::GO:0014003; P:oligodendrocyte development; ISS:UniProtKB.::GO:0001541; P:ovarian follicle development; ISS:UniProtKB.::GO:0045948; P:positive regulation of translational initiation; ISS:UniProtKB.::GO:0009749; P:response to glucose stimulus; ISS:UniProtKB.::GO:0009408; P:response to heat; ISS:UniProtKB.::GO:0043434; P:response to peptide hormone stimulus; ISS:UniProtKB.::GO:0016070; P:RNA metabolic process; IEA:InterPro. | 6 | P47823 | 721 | EI2BE_RABIT Translation initiation factor eIF... | 714 | 3e-99 | 328 | 30 | 51 | GO:0005851; C:eukaryotic translation initiation factor 2B complex; ISS:UniProtKB. | | | | | | | | | | GO:0005085; F:guanyl-nucleotide exchange factor activity; IMP:UniProtKB.::GO:0016740; F:transferase activity; IEA:InterPro.::GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0014002; P:astrocyte development; ISS:UniProtKB.::GO:0051716; P:cellular response to stimulus; ISS:UniProtKB.::GO:0042552; P:myelination; ISS:UniProtKB.::GO:0014003; P:oligodendrocyte development; ISS:UniProtKB.::GO:0001541; P:ovarian follicle development; ISS:UniProtKB.::GO:0045948; P:positive regulation of translational initiation; IMP:UniProtKB.::GO:0009749; P:response to glucose stimulus; ISS:UniProtKB.::GO:0009408; P:response to heat; ISS:UniProtKB.::GO:0043434; P:response to peptide hormone stimulus; ISS:UniProtKB.::GO:0016070; P:RNA metabolic process; IEA:InterPro. | 7 | Q13144 | 721 | EI2BE_HUMAN Translation initiation factor eIF... | 711 | 7e-95 | 316 | 30 | 51 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005851; C:eukaryotic translation initiation factor 2B complex; IDA:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0005085; F:guanyl-nucleotide exchange factor activity; IMP:UniProtKB.::GO:0016740; F:transferase activity; IEA:InterPro.::GO:0003743; F:translation initiation factor activity; NAS:UniProtKB.::GO:0031369; F:translation initiation factor binding; ISS:UniProtKB. | | | | | | | | | | GO:0014002; P:astrocyte development; IMP:UniProtKB.::GO:0042552; P:myelination; IMP:UniProtKB.::GO:0032057; P:negative regulation of translational initiation in response to stress; ISS:UniProtKB.::GO:0014003; P:oligodendrocyte development; IMP:UniProtKB.::GO:0001541; P:ovarian follicle development; IMP:UniProtKB.::GO:0045948; P:positive regulation of translational initiation; ISS:UniProtKB.::GO:0009749; P:response to glucose stimulus; ISS:UniProtKB.::GO:0009408; P:response to heat; IMP:UniProtKB.::GO:0043434; P:response to peptide hormone stimulus; ISS:UniProtKB.::GO:0016070; P:RNA metabolic process; IEA:InterPro. | 8 | Q64350 | 716 | EI2BE_RAT Translation initiation factor eIF-2... | 473 | 1e-93 | 313 | 36 | 57 | GO:0005851; C:eukaryotic translation initiation factor 2B complex; ISS:UniProtKB. | | | | | | | | | | GO:0005085; F:guanyl-nucleotide exchange factor activity; IDA:MGI.::GO:0016740; F:transferase activity; IEA:InterPro.::GO:0003743; F:translation initiation factor activity; TAS:RGD.::GO:0031369; F:translation initiation factor binding; IDA:RGD. | | | | | | | | | | GO:0014002; P:astrocyte development; ISS:UniProtKB.::GO:0042552; P:myelination; ISS:UniProtKB.::GO:0032057; P:negative regulation of translational initiation in response to stress; IMP:RGD.::GO:0014003; P:oligodendrocyte development; ISS:UniProtKB.::GO:0001541; P:ovarian follicle development; ISS:UniProtKB.::GO:0045948; P:positive regulation of translational initiation; ISS:UniProtKB.::GO:0009749; P:response to glucose stimulus; IDA:UniProtKB.::GO:0009408; P:response to heat; IDA:UniProtKB.::GO:0043434; P:response to peptide hormone stimulus; IDA:UniProtKB.::GO:0016070; P:RNA metabolic process; IEA:InterPro. | 9 | P56288 | 458 | EI2BG_SCHPO Probable translation initiation f... | 417 | 0.000000000000002 | 83.2 | 25 | 42 | GO:0005829; C:cytosol; IDA:PomBase.::GO:0005851; C:eukaryotic translation initiation factor 2B complex; ISS:PomBase.::GO:0005840; C:ribosome; ISS:PomBase. | | | | | | | | | | GO:0016779; F:nucleotidyltransferase activity; IEA:InterPro.::GO:0003743; F:translation initiation factor activity; ISS:PomBase. | | | | | | | | | | GO:0002183; P:cytoplasmic translational initiation; NAS:PomBase. | 10 | P37820 | 359 | MPG1_SULAC Putative mannose-1-phosphate guany... | 125 | 0.000006 | 52.8 | 30 | 52 | | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0004475; F:mannose-1-phosphate guanylyltransferase activity; IEA:EC. | | | | | | | | | | GO:0009058; P:biosynthetic process; IEA:InterPro. | 11 | Q8BTZ7 | 360 | GMPPB_MOUSE Mannose-1-phosphate guanyltransfe... | 419 | 0.000000000005 | 71.6 | 22 | 40 | GO:0005739; C:mitochondrion; IDA:MGI. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0004475; F:mannose-1-phosphate guanylyltransferase activity; IEA:EC. | | | | | | | | | | GO:0009058; P:biosynthetic process; IEA:InterPro. | 12 | P0C5I2 | 360 | GMPPB_PIG Mannose-1-phosphate guanyltransfera... | 424 | 0.00000000002 | 69.7 | 22 | 39 | | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0004475; F:mannose-1-phosphate guanylyltransferase activity; IDA:MGI. | | | | | | | | | | GO:0009058; P:biosynthetic process; IEA:InterPro. | 13 | Q9Y5P6 | 360 | GMPPB_HUMAN Mannose-1-phosphate guanyltransfe... | 424 | 0.00000000006 | 68.6 | 22 | 39 | | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0004475; F:mannose-1-phosphate guanylyltransferase activity; IEA:EC. | | | | | | | | | | GO:0006488; P:dolichol-linked oligosaccharide biosynthetic process; TAS:Reactome.::GO:0009298; P:GDP-mannose biosynthetic process; TAS:Reactome.::GO:0043687; P:post-translational protein modification; TAS:Reactome.::GO:0018279; P:protein N-linked glycosylation via asparagine; TAS:Reactome. | 14 | P70541 | 452 | EI2BG_RAT Translation initiation factor eIF-2... | 462 | 0.00000000007 | 68.6 | 21 | 41 | GO:0005851; C:eukaryotic translation initiation factor 2B complex; ISS:UniProtKB.::GO:0005625; C:soluble fraction; IDA:RGD. | | | | | | | | | | GO:0005085; F:guanyl-nucleotide exchange factor activity; IDA:RGD.::GO:0016779; F:nucleotidyltransferase activity; IEA:InterPro.::GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0032057; P:negative regulation of translational initiation in response to stress; IMP:RGD.::GO:0014003; P:oligodendrocyte development; ISS:UniProtKB.::GO:0009749; P:response to glucose stimulus; IDA:UniProtKB.::GO:0009408; P:response to heat; IDA:UniProtKB.::GO:0043434; P:response to peptide hormone stimulus; IDA:UniProtKB. | 15 | Q4U3E8 | 364 | MPG1_ASPFU Mannose-1-phosphate guanyltransfer... | 408 | 0.00000000009 | 67.8 | 21 | 41 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0004475; F:mannose-1-phosphate guanylyltransferase activity; IEA:EC. | | | | | | | | | | GO:0009058; P:biosynthetic process; IEA:InterPro.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW. | 16 | Q6CCU3 | 363 | MPG1_YARLI Mannose-1-phosphate guanyltransfer... | 409 | 0.0000000002 | 67 | 20 | 40 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0004475; F:mannose-1-phosphate guanylyltransferase activity; IEA:EC. | | | | | | | | | | GO:0009058; P:biosynthetic process; IEA:InterPro.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW. | 17 | A5PJI7 | 452 | EI2BG_BOVIN Translation initiation factor eIF... | 469 | 0.0000000002 | 67.4 | 21 | 40 | GO:0005851; C:eukaryotic translation initiation factor 2B complex; ISS:UniProtKB. | | | | | | | | | | GO:0016779; F:nucleotidyltransferase activity; IEA:InterPro.::GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051716; P:cellular response to stimulus; ISS:UniProtKB.::GO:0014003; P:oligodendrocyte development; ISS:UniProtKB. | 18 | Q7SXP8 | 422 | GMPAB_DANRE Mannose-1-phosphate guanyltransfe... | 383 | 0.0000000002 | 67 | 20 | 42 | | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0004475; F:mannose-1-phosphate guanylyltransferase activity; IEA:EC. | | | | | | | | | | GO:0009058; P:biosynthetic process; IEA:InterPro. | 19 | Q2UJU5 | 364 | MPG1_ASPOR Mannose-1-phosphate guanyltransfer... | 418 | 0.0000000003 | 66.2 | 21 | 41 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0004475; F:mannose-1-phosphate guanylyltransferase activity; IEA:EC. | | | | | | | | | | GO:0009058; P:biosynthetic process; IEA:InterPro.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW. | 20 | Q2YDJ9 | 360 | GMPPB_BOVIN Mannose-1-phosphate guanyltransfe... | 424 | 0.0000000004 | 65.9 | 22 | 39 | | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0004475; F:mannose-1-phosphate guanylyltransferase activity; IEA:EC. | | | | | | | | | | GO:0009058; P:biosynthetic process; IEA:InterPro. | 21 | A3QMC8 | 365 | GMPPB_CAEEL Mannose-1-phosphate guanyltransfe... | 101 | 4.4 | 34.3 | 32 | 47 | | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0004475; F:mannose-1-phosphate guanylyltransferase activity; IEA:EC. | | | | | | | | | | GO:0009058; P:biosynthetic process; IEA:InterPro.::GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040007; P:growth; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0048477; P:oogenesis; IMP:WormBase.::GO:0006898; P:receptor-mediated endocytosis; IMP:WormBase. | 22 | Q68EY9 | 360 | GMPBA_XENLA Mannose-1-phosphate guanyltransfe... | 419 | 0.0000000006 | 65.5 | 23 | 41 | | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0004475; F:mannose-1-phosphate guanylyltransferase activity; IEA:EC. | | | | | | | | | | GO:0009058; P:biosynthetic process; IEA:InterPro. | 23 | Q7RVR8 | 364 | MPG1_NEUCR Mannose-1-phosphate guanyltransfer... | 96 | 0.1 | 39.3 | 26 | 49 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0004475; F:mannose-1-phosphate guanylyltransferase activity; IEA:EC. | | | | | | | | | | GO:0009058; P:biosynthetic process; IEA:InterPro.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW. | 24 | Q68EQ1 | 360 | GMPPB_XENTR Mannose-1-phosphate guanyltransfe... | 423 | 0.0000000007 | 65.1 | 23 | 41 | | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0004475; F:mannose-1-phosphate guanylyltransferase activity; IEA:EC. | | | | | | | | | | GO:0009058; P:biosynthetic process; IEA:InterPro. | 25 | A2VD83 | 360 | GMPBB_XENLA Mannose-1-phosphate guanyltransfe... | 421 | 0.0000000009 | 64.7 | 21 | 41 | | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0004475; F:mannose-1-phosphate guanylyltransferase activity; IEA:EC. | | | | | | | | | | GO:0009058; P:biosynthetic process; IEA:InterPro. | 26 | B3W9A3 | 380 | GLGC_LACCB Glucose-1-phosphate adenylyltransf... | 422 | 0.0000000009 | 64.7 | 22 | 39 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008878; F:glucose-1-phosphate adenylyltransferase activity; IEA:EC. | | | | | | | | | | GO:0005978; P:glycogen biosynthetic process; IEA:UniProtKB-KW. | 27 | Q036S8 | 380 | GLGC_LACC3 Glucose-1-phosphate adenylyltransf... | 422 | 0.0000000009 | 64.7 | 22 | 39 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008878; F:glucose-1-phosphate adenylyltransferase activity; IEA:EC. | | | | | | | | | | GO:0005978; P:glycogen biosynthetic process; IEA:UniProtKB-KW. | 28 | Q96IJ6 | 420 | GMPPA_HUMAN Mannose-1-phosphate guanyltransfe... | 394 | 0.000000002 | 64.3 | 22 | 43 | | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0004475; F:mannose-1-phosphate guanylyltransferase activity; IEA:EC. | | | | | | | | | | GO:0006488; P:dolichol-linked oligosaccharide biosynthetic process; TAS:Reactome.::GO:0009298; P:GDP-mannose biosynthetic process; TAS:Reactome.::GO:0043687; P:post-translational protein modification; TAS:Reactome.::GO:0018279; P:protein N-linked glycosylation via asparagine; TAS:Reactome. | 29 | B0CM52 | 420 | GMPPA_PAPAN Mannose-1-phosphate guanyltransfe... | 394 | 0.000000002 | 63.9 | 22 | 44 | | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0004475; F:mannose-1-phosphate guanylyltransferase activity; IEA:EC. | | | | | | | | | | GO:0009058; P:biosynthetic process; IEA:InterPro. | 30 | Q5B1J4 | 364 | MPG1_EMENI Mannose-1-phosphate guanyltransfer... | 404 | 0.000000003 | 63.2 | 20 | 43 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0004475; F:mannose-1-phosphate guanylyltransferase activity; IEA:EC. | | | | | | | | | | GO:0009058; P:biosynthetic process; IEA:InterPro.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW. | 31 | Q9P8N0 | 364 | MPG1_PICAN Mannose-1-phosphate guanyltransfer... | 434 | 0.000000003 | 63.2 | 22 | 40 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0004475; F:mannose-1-phosphate guanylyltransferase activity; IEA:EC. | | | | | | | | | | GO:0009058; P:biosynthetic process; IEA:InterPro.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW. |
