Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Candida albicans WO1
Locus:
CAWG_00530
Length:
938
Number of sequences:
5931
Description:
KEX1 protease precursor
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1O13359    938   KEX2_CANAW Kexin OS=Candida albicans (strain ...9380     1949     100     100GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
2P09231    756   KEX1A_KLULA Protease KEX1 OS=1267 / NRRL Y-11...7000     692     52     66GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
3P13134    814   KEX2_YEAST Kexin OS=Saccharomyces cerevisiae ...8520     644     43     59GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005802; C:trans-Golgi network; IDA:SGD.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004252; F:serine-type endopeptidase activity; IDA:SGD.
GO:0007323; P:peptide pheromone maturation; IMP:SGD.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
4P42781    976   XPR6_YARLI Dibasic-processing endoprotease OS...1560.041     41.6     25     41GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
5Q09175    709   KRP1_SCHPO Dibasic-processing endoprotease OS...5373e-146     457     42     63GO:0009986; C:cell surface; NAS:PomBase.::GO:0005794; C:Golgi apparatus; IDA:PomBase.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0004252; F:serine-type endopeptidase activity; IDA:PomBase.
GO:0071432; P:peptide mating pheromone maturation involved in conjugation with cellular fusion; TAS:PomBase.::GO:0016485; P:protein processing; ISS:RefGenome.::GO:0006508; P:proteolysis; IGI:PomBase.
6Q62849    783   PCSK7_RAT Proprotein convertase subtilisin/ke...5067e-109     361     40     61
GO:0004252; F:serine-type endopeptidase activity; IBA:RefGenome.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
7Q16549    785   PCSK7_HUMAN Proprotein convertase subtilisin/...5042e-108     359     40     61GO:0030173; C:integral to Golgi membrane; IDA:UniProtKB.
GO:0004252; F:serine-type endopeptidase activity; IBA:RefGenome.
GO:0016486; P:peptide hormone processing; NAS:UniProtKB.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
8P29119    783   FURI1_XENLA Furin-1 OS=Xenopus laevis (Africa...4734e-107     356     40     60GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
9Q61139    770   PCSK7_MOUSE Proprotein convertase subtilisin/...5051e-106     354     39     61GO:0005788; C:endoplasmic reticulum lumen; TAS:Reactome.
GO:0004252; F:serine-type endopeptidase activity; IBA:RefGenome.
GO:0016485; P:protein processing; IBA:RefGenome.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
10P23377    793   FURIN_RAT Furin OS=Rattus norvegicus (Rat). G...4731e-104     349     40     60GO:0005789; C:endoplasmic reticulum membrane; IDA:RGD.::GO:0005615; C:extracellular space; IBA:RefGenome.::GO:0031985; C:Golgi cisterna; IDA:RGD.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IDA:RGD.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004252; F:serine-type endopeptidase activity; IMP:RGD.
GO:0007568; P:aging; IEP:RGD.::GO:0030335; P:positive regulation of cell migration; IMP:RGD.::GO:0030511; P:positive regulation of transforming growth factor beta receptor signaling pathway; IMP:RGD.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
11P23188    793   FURIN_MOUSE Furin OS=Mus musculus (Mouse). GN...4735e-104     348     40     60GO:0005769; C:early endosome; TAS:MGI.::GO:0005788; C:endoplasmic reticulum lumen; TAS:Reactome.::GO:0005615; C:extracellular space; IBA:RefGenome.::GO:0016021; C:integral to membrane; TAS:MGI.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0012510; C:trans-Golgi network transport vesicle membrane; TAS:MGI.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004252; F:serine-type endopeptidase activity; IBA:RefGenome.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
12P09958    794   FURIN_HUMAN Furin OS=Homo sapiens (Human). GN...4738e-104     347     40     59GO:0009986; C:cell surface; IDA:BHF-UCL.::GO:0005796; C:Golgi lumen; TAS:Reactome.::GO:0000139; C:Golgi membrane; TAS:Reactome.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0045121; C:membrane raft; IDA:BHF-UCL.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0005802; C:trans-Golgi network; IDA:BHF-UCL.::GO:0030140; C:trans-Golgi network transport vesicle; IDA:MGI.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0048406; F:nerve growth factor binding; IDA:BHF-UCL.::GO:0042277; F:peptide binding; IDA:BHF-UCL.::GO:0002020; F:protease binding; IPI:BHF-UCL.::GO:0004252; F:serine-type endopeptidase activity; IDA:BHF-UCL.::GO:0004867; F:serine-type endopeptidase inhibitor activity; IDA:BHF-UCL.
GO:0008283; P:cell proliferation; IMP:BHF-UCL.::GO:0022617; P:extracellular matrix disassembly; TAS:Reactome.::GO:0032804; P:negative regulation of low-density lipoprotein particle receptor catabolic process; IDA:HGNC.::GO:0032911; P:negative regulation of transforming growth factor beta1 production; IMP:BHF-UCL.::GO:0032455; P:nerve growth factor processing; TAS:Reactome.::GO:0032902; P:nerve growth factor production; IDA:BHF-UCL.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0007219; P:Notch signaling pathway; TAS:Reactome.::GO:0043043; P:peptide biosynthetic process; IDA:BHF-UCL.::GO:0017187; P:peptidyl-glutamic acid carboxylation; TAS:Reactome.::GO:0051044; P:positive regulation of membrane protein ectodomain proteolysis; IC:BHF-UCL.::GO:0043687; P:post-translational protein modification; TAS:Reactome.::GO:0006508; P:proteolysis; TAS:Reactome.::GO:0032940; P:secretion by cell; IDA:BHF-UCL.::GO:0006465; P:signal peptide processing; IDA:HGNC.::GO:0007179; P:transforming growth factor beta receptor signaling pathway; TAS:Reactome.::GO:0019067; P:viral assembly, maturation, egress, and release; IEP:BHF-UCL.
13Q28193    797   FURIN_BOVIN Furin OS=Bos taurus (Bovine). GN=...4734e-103     345     40     59GO:0005615; C:extracellular space; ISS:RefGenome.::GO:0005794; C:Golgi apparatus; ISS:RefGenome.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004252; F:serine-type endopeptidase activity; ISS:RefGenome.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
14P30432    1679   FUR2_DROME Furin-like protease 2 OS=Drosophil...6308e-98     342     34     50GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; ISS:FlyBase.
GO:0005524; F:ATP binding; IEA:InterPro.::GO:0004252; F:serine-type endopeptidase activity; IDA:FlyBase.::GO:0004714; F:transmembrane receptor protein tyrosine kinase activity; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0007169; P:transmembrane receptor protein tyrosine kinase signaling pathway; IEA:InterPro.
15P63239    753   NEC1_MOUSE Neuroendocrine convertase 1 OS=Mus...7331e-96     327     30     50GO:0005788; C:endoplasmic reticulum lumen; TAS:Reactome.::GO:0005615; C:extracellular space; IDA:BHF-UCL.::GO:0005794; C:Golgi apparatus; IBA:RefGenome.::GO:0030141; C:secretory granule; TAS:Reactome.::GO:0030133; C:transport vesicle; IEA:UniProtKB-SubCell.
GO:0004252; F:serine-type endopeptidase activity; IDA:BHF-UCL.
GO:0043043; P:peptide biosynthetic process; IDA:BHF-UCL.::GO:0016486; P:peptide hormone processing; IDA:BHF-UCL.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
16P63240    753   NEC1_MUSCO Neuroendocrine convertase 1 OS=Mus...7331e-96     327     30     50GO:0030133; C:transport vesicle; IEA:UniProtKB-SubCell.
GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
17P28840    752   NEC1_RAT Neuroendocrine convertase 1 OS=Rattu...4893e-95     323     37     57GO:0043679; C:axon terminus; IDA:RGD.::GO:0030425; C:dendrite; IDA:RGD.::GO:0005615; C:extracellular space; IDA:RGD.::GO:0043025; C:neuronal cell body; IDA:RGD.::GO:0048471; C:perinuclear region of cytoplasm; IDA:RGD.::GO:0005791; C:rough endoplasmic reticulum; IDA:RGD.::GO:0030141; C:secretory granule; IDA:RGD.::GO:0005802; C:trans-Golgi network; IDA:RGD.::GO:0030133; C:transport vesicle; IEA:UniProtKB-SubCell.
GO:0051087; F:chaperone binding; IPI:RGD.::GO:0043559; F:insulin binding; IPI:RGD.::GO:0004252; F:serine-type endopeptidase activity; IBA:RefGenome.
GO:0009790; P:embryo development; IEP:RGD.::GO:0022008; P:neurogenesis; IEP:RGD.::GO:0031016; P:pancreas development; IEP:RGD.::GO:0016486; P:peptide hormone processing; IDA:RGD.::GO:0021983; P:pituitary gland development; IEP:RGD.::GO:0050714; P:positive regulation of protein secretion; IDA:RGD.::GO:0016540; P:protein autoprocessing; IMP:RGD.::GO:0006508; P:proteolysis; IMP:RGD.::GO:0048678; P:response to axon injury; IEP:RGD.::GO:0051592; P:response to calcium ion; IEP:RGD.::GO:0010157; P:response to chlorate; IEP:RGD.::GO:0042493; P:response to drug; IEP:RGD.::GO:0070542; P:response to fatty acid; IEP:RGD.::GO:0051384; P:response to glucocorticoid stimulus; IEP:RGD.::GO:0009749; P:response to glucose stimulus; IEP:RGD.::GO:0070555; P:response to interleukin-1; IEP:RGD.::GO:0032496; P:response to lipopolysaccharide; IEP:RGD.::GO:0043278; P:response to morphine; IEP:RGD.::GO:0031667; P:response to nutrient levels; IEP:RGD.::GO:0043434; P:response to peptide hormone stimulus; IEP:RGD.
18P29120    753   NEC1_HUMAN Neuroendocrine convertase 1 OS=Hom...5986e-95     322     33     52GO:0005615; C:extracellular space; IDA:BHF-UCL.::GO:0005794; C:Golgi apparatus; IBA:RefGenome.::GO:0030141; C:secretory granule; TAS:Reactome.::GO:0030133; C:transport vesicle; IEA:UniProtKB-SubCell.
GO:0004252; F:serine-type endopeptidase activity; ISS:BHF-UCL.
GO:0007267; P:cell-cell signaling; TAS:ProtInc.::GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.::GO:0006112; P:energy reserve metabolic process; TAS:Reactome.::GO:0043043; P:peptide biosynthetic process; ISS:BHF-UCL.::GO:0016486; P:peptide hormone processing; TAS:Reactome.::GO:0006508; P:proteolysis; TAS:ProtInc.::GO:0050796; P:regulation of insulin secretion; TAS:Reactome.::GO:0044281; P:small molecule metabolic process; TAS:Reactome.
19Q9GLR1    753   NEC1_BOVIN Neuroendocrine convertase 1 OS=Bos...5996e-95     322     33     52GO:0005615; C:extracellular space; ISS:RefGenome.::GO:0005794; C:Golgi apparatus; ISS:RefGenome.::GO:0030133; C:transport vesicle; IEA:UniProtKB-SubCell.
GO:0004252; F:serine-type endopeptidase activity; ISS:RefGenome.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
20Q6UW60    755   PCSK4_HUMAN Proprotein convertase subtilisin/...4524e-94     320     37     59GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0004252; F:serine-type endopeptidase activity; IBA:RefGenome.
GO:0006508; P:proteolysis; IBA:RefGenome.
21P29121    655   PCSK4_MOUSE Proprotein convertase subtilisin/...4523e-93     315     36     58GO:0002080; C:acrosomal membrane; IDA:MGI.::GO:0005788; C:endoplasmic reticulum lumen; TAS:Reactome.
GO:0004252; F:serine-type endopeptidase activity; IBA:RefGenome.
GO:0007340; P:acrosome reaction; IMP:MGI.::GO:0007339; P:binding of sperm to zona pellucida; IMP:MGI.::GO:0006508; P:proteolysis; IBA:RefGenome.::GO:0048240; P:sperm capacitation; IMP:MGI.
22Q78EH2    678   PCSK4_RAT Proprotein convertase subtilisin/ke...4523e-93     315     36     59
GO:0004252; F:serine-type endopeptidase activity; IBA:RefGenome.
GO:0006508; P:proteolysis; IBA:RefGenome.
23P28841    637   NEC2_RAT Neuroendocrine convertase 2 OS=Rattu...5211e-92     313     36     57GO:0005615; C:extracellular space; IBA:RefGenome.::GO:0030133; C:transport vesicle; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0004252; F:serine-type endopeptidase activity; IMP:BHF-UCL.
GO:0034231; P:islet amyloid polypeptide processing; IMP:BHF-UCL.::GO:0006508; P:proteolysis; IMP:RGD.
24Q5REC2    638   NEC2_PONAB Neuroendocrine convertase 2 OS=Pon...4922e-92     312     37     58GO:0030133; C:transport vesicle; IEA:UniProtKB-SubCell.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
25P16519    638   NEC2_HUMAN Neuroendocrine convertase 2 OS=Hom...4922e-92     312     37     58GO:0005615; C:extracellular space; IDA:BHF-UCL.::GO:0016020; C:membrane; IDA:BHF-UCL.::GO:0030141; C:secretory granule; TAS:Reactome.::GO:0005625; C:soluble fraction; IDA:BHF-UCL.::GO:0030133; C:transport vesicle; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
GO:0034230; P:enkephalin processing; ISS:BHF-UCL.::GO:0030070; P:insulin processing; IDA:BHF-UCL.::GO:0034231; P:islet amyloid polypeptide processing; ISS:BHF-UCL.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
26P21661    637   NEC2_MOUSE Neuroendocrine convertase 2 OS=Mus...5214e-92     311     35     57GO:0005788; C:endoplasmic reticulum lumen; TAS:Reactome.::GO:0005615; C:extracellular space; IDA:BHF-UCL.::GO:0030133; C:transport vesicle; IEA:UniProtKB-SubCell.
GO:0004252; F:serine-type endopeptidase activity; IDA:BHF-UCL.
GO:0034230; P:enkephalin processing; IDA:BHF-UCL.::GO:0007399; P:nervous system development; IEP:HGNC.::GO:0016540; P:protein autoprocessing; IDA:HGNC.::GO:0006508; P:proteolysis; IMP:MGI.
27Q03333    638   NEC2_PIG Neuroendocrine convertase 2 OS=Sus s...4915e-92     311     36     58GO:0030133; C:transport vesicle; IEA:UniProtKB-SubCell.
GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
28Q9GLR0    638   NEC2_BOVIN Neuroendocrine convertase 2 OS=Bos...4923e-91     309     36     56GO:0005615; C:extracellular space; ISS:RefGenome.::GO:0030133; C:transport vesicle; IEA:UniProtKB-SubCell.
GO:0004252; F:serine-type endopeptidase activity; ISS:RefGenome.
GO:0007399; P:nervous system development; ISS:AgBase.::GO:0016486; P:peptide hormone processing; ISS:AgBase.::GO:0016540; P:protein autoprocessing; ISS:AgBase.::GO:0006508; P:proteolysis; ISS:AgBase.
29Q04592    1877   PCSK5_MOUSE Proprotein convertase subtilisin/...5116e-91     323     35     56GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0005788; C:endoplasmic reticulum lumen; TAS:Reactome.::GO:0005615; C:extracellular space; IDA:BHF-UCL.::GO:0005794; C:Golgi apparatus; IDA:MGI.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0030141; C:secretory granule; IDA:MGI.
GO:0042277; F:peptide binding; IDA:BHF-UCL.::GO:0004252; F:serine-type endopeptidase activity; IDA:BHF-UCL.
GO:0009952; P:anterior/posterior pattern specification; IMP:BHF-UCL.::GO:0042089; P:cytokine biosynthetic process; IDA:BHF-UCL.::GO:0007566; P:embryo implantation; IMP:BHF-UCL.::GO:0048566; P:embryonic digestive tract development; IMP:BHF-UCL.::GO:0048706; P:embryonic skeletal system development; IMP:BHF-UCL.::GO:0007507; P:heart development; IMP:BHF-UCL.::GO:0001822; P:kidney development; IMP:BHF-UCL.::GO:0035108; P:limb morphogenesis; IMP:BHF-UCL.::GO:0043043; P:peptide biosynthetic process; IDA:BHF-UCL.::GO:0016486; P:peptide hormone processing; IDA:BHF-UCL.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0030323; P:respiratory tube development; IMP:BHF-UCL.::GO:0019067; P:viral assembly, maturation, egress, and release; IDA:BHF-UCL.
30Q92824    1860   PCSK5_HUMAN Proprotein convertase subtilisin/...5116e-91     323     35     56GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0005615; C:extracellular space; ISS:BHF-UCL.::GO:0005796; C:Golgi lumen; TAS:Reactome.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0030141; C:secretory granule; ISS:BHF-UCL.
GO:0042277; F:peptide binding; ISS:BHF-UCL.::GO:0004252; F:serine-type endopeptidase activity; IDA:BHF-UCL.
GO:0009952; P:anterior/posterior pattern specification; IMP:BHF-UCL.::GO:0007267; P:cell-cell signaling; TAS:ProtInc.::GO:0042089; P:cytokine biosynthetic process; ISS:BHF-UCL.::GO:0007566; P:embryo implantation; ISS:BHF-UCL.::GO:0048566; P:embryonic digestive tract development; IMP:BHF-UCL.::GO:0048706; P:embryonic skeletal system development; IMP:BHF-UCL.::GO:0007507; P:heart development; ISS:BHF-UCL.::GO:0001822; P:kidney development; IMP:BHF-UCL.::GO:0035108; P:limb morphogenesis; ISS:BHF-UCL.::GO:0032455; P:nerve growth factor processing; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0043043; P:peptide biosynthetic process; IDA:BHF-UCL.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0002001; P:renin secretion into blood stream; IEP:BHF-UCL.::GO:0030323; P:respiratory tube development; ISS:BHF-UCL.::GO:0006465; P:signal peptide processing; IDA:HGNC.::GO:0019067; P:viral assembly, maturation, egress, and release; IEP:BHF-UCL.
31P30430    1101   FUR1C_DROME Furin-like protease 1, isoform 1-...4677e-91     318     37     58GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IDA:FlyBase.
GO:0004252; F:serine-type endopeptidase activity; IDA:FlyBase.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
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