| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
121 | Q9Y6E7 | 314 | SIR4_HUMAN NAD-dependent protein deacetylase ... | 193 | 0.00000003 | 58.9 | 27 | 44 | GO:0005759; C:mitochondrial matrix; IDA:UniProtKB. | | | | | | | | | | GO:0003950; F:NAD+ ADP-ribosyltransferase activity; IDA:UniProtKB.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006342; P:chromatin silencing; TAS:ProtInc.::GO:0046676; P:negative regulation of insulin secretion; IMP:UniProtKB.::GO:0006471; P:protein ADP-ribosylation; TAS:BHF-UCL.::GO:0006476; P:protein deacetylation; IEA:InterPro. | 122 | Q8N6T7 | 355 | SIR6_HUMAN NAD-dependent protein deacetylase ... | 134 | 0.00000003 | 58.9 | 30 | 49 | GO:0005724; C:nuclear telomeric heterochromatin; IDA:UniProtKB.::GO:0005654; C:nucleoplasm; IDA:UniProtKB. | | | | | | | | | | GO:0003956; F:NAD(P)+-protein-arginine ADP-ribosyltransferase activity; ISS:UniProtKB.::GO:0003950; F:NAD+ ADP-ribosyltransferase activity; TAS:BHF-UCL.::GO:0070403; F:NAD+ binding; ISS:UniProtKB.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0008270; F:zinc ion binding; ISS:UniProtKB. | | | | | | | | | | GO:0006471; P:protein ADP-ribosylation; ISS:UniProtKB.::GO:0010569; P:regulation of double-strand break repair via homologous recombination; IDA:UniProtKB. | 123 | Q1JQC6 | 315 | SIR4_BOVIN NAD-dependent protein deacetylase ... | 193 | 0.00000003 | 58.5 | 28 | 44 | GO:0005759; C:mitochondrial matrix; IDA:UniProtKB. | | | | | | | | | | GO:0003950; F:NAD+ ADP-ribosyltransferase activity; ISS:UniProtKB.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0046676; P:negative regulation of insulin secretion; ISS:UniProtKB.::GO:0006476; P:protein deacetylation; IEA:InterPro. | 124 | Q9RL35 | 299 | NPD1_STRCO NAD-dependent protein deacetylase ... | 144 | 0.00000004 | 58.2 | 28 | 47 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro. | 125 | A8NWP2 | 299 | SIR5_COPC7 NAD-dependent protein deacylase OS... | 204 | 0.00000005 | 57.8 | 23 | 40 | | | | | | | | | | | GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro. | 126 | Q6MJJ2 | 235 | NPD_BDEBA NAD-dependent protein deacylase OS=... | 164 | 0.00000005 | 57 | 30 | 47 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro. | 127 | Q9VAQ1 | 771 | SIR7_DROME NAD-dependent protein deacetylase ... | 133 | 0.00000006 | 58.9 | 29 | 50 | | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro. | 128 | Q68F47 | 309 | SIR5B_XENLA NAD-dependent protein deacylase s... | 129 | 0.0000001 | 56.6 | 29 | 47 | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070403; F:NAD+ binding; ISS:UniProtKB.::GO:0036054; F:protein-malonyllysine demalonylase activity; ISS:UniProtKB.::GO:0036055; F:protein-succinyllysine desuccinylase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; ISS:UniProtKB. | | | | | | | | | | | 129 | Q0P595 | 400 | SIR7_BOVIN NAD-dependent protein deacetylase ... | 132 | 0.0000002 | 56.6 | 24 | 44 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005731; C:nucleolus organizer region; ISS:UniProtKB. | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007072; P:positive regulation of transcription on exit from mitosis; ISS:UniProtKB.::GO:0006476; P:protein deacetylation; IEA:InterPro.::GO:0009303; P:rRNA transcription; ISS:UniProtKB. | 130 | Q5L014 | 242 | NPD1_GEOKA NAD-dependent protein deacetylase ... | 134 | 0.0000002 | 55.5 | 29 | 46 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro. | 131 | Q9NRC8 | 400 | SIR7_HUMAN NAD-dependent protein deacetylase ... | 132 | 0.0000003 | 56.2 | 24 | 45 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005731; C:nucleolus organizer region; IDA:UniProtKB. | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007072; P:positive regulation of transcription on exit from mitosis; IMP:UniProtKB.::GO:0006476; P:protein deacetylation; IEA:InterPro.::GO:0009303; P:rRNA transcription; IMP:UniProtKB. | 132 | Q8PQK3 | 293 | NPD_XANAC NAD-dependent protein deacetylase O... | 142 | 0.0000003 | 55.5 | 29 | 44 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro. | 133 | Q8FRV5 | 254 | NPD2_COREF NAD-dependent protein deacylase 2 ... | 196 | 0.0000004 | 54.7 | 23 | 41 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro. | 134 | Q8NSM4 | 258 | NPD_CORGL NAD-dependent protein deacylase OS=... | 165 | 0.0000004 | 54.7 | 26 | 42 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro. | 135 | Q72RR0 | 246 | NPD_LEPIC NAD-dependent protein deacylase OS=... | 162 | 0.0000005 | 54.3 | 31 | 43 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro. | 136 | Q8F3Z6 | 246 | NPD_LEPIN NAD-dependent protein deacylase OS=... | 162 | 0.0000005 | 54.3 | 31 | 43 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro. | 137 | Q8PDM9 | 293 | NPD_XANCP NAD-dependent protein deacetylase O... | 141 | 0.0000006 | 54.7 | 28 | 45 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro. | 138 | Q4UZX0 | 293 | NPD_XANC8 NAD-dependent protein deacetylase O... | 141 | 0.0000006 | 54.7 | 28 | 45 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro. | 139 | Q5AI90 | 306 | SIR5_CANAL NAD-dependent protein deacylase OS... | 135 | 0.0000007 | 54.7 | 29 | 44 | | | | | | | | | | | GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro. | 140 | Q95Q89 | 292 | SIR24_CAEEL NAD-dependent protein deacetylase... | 134 | 0.0000008 | 54.3 | 26 | 43 | | | | | | | | | | | GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro. | 141 | Q20480 | 287 | SIR41_CAEEL NAD-dependent protein deacetylase... | 198 | 0.0000009 | 53.9 | 25 | 40 | | | | | | | | | | | GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro.::GO:0006974; P:response to DNA damage stimulus; IMP:WormBase. | 142 | Q8BKJ9 | 402 | SIR7_MOUSE NAD-dependent protein deacetylase ... | 132 | 0.000001 | 54.3 | 23 | 45 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005731; C:nucleolus organizer region; ISS:UniProtKB. | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007072; P:positive regulation of transcription on exit from mitosis; ISS:UniProtKB.::GO:0006476; P:protein deacetylation; IEA:InterPro.::GO:0009303; P:rRNA transcription; ISS:UniProtKB. | 143 | Q4Q2Y6 | 243 | SIR5_LEIMA NAD-dependent protein deacetylase ... | 160 | 0.000001 | 53.1 | 28 | 46 | | | | | | | | | | | GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro. | 144 | P59941 | 334 | SIR6_MOUSE NAD-dependent protein deacetylase ... | 132 | 0.000001 | 53.9 | 30 | 47 | GO:0005724; C:nuclear telomeric heterochromatin; ISS:UniProtKB.::GO:0005654; C:nucleoplasm; ISS:UniProtKB. | | | | | | | | | | GO:0003956; F:NAD(P)+-protein-arginine ADP-ribosyltransferase activity; IDA:UniProtKB.::GO:0070403; F:NAD+ binding; ISS:UniProtKB.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); ISS:UniProtKB.::GO:0005515; F:protein binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; ISS:UniProtKB. | | | | | | | | | | GO:0006471; P:protein ADP-ribosylation; IDA:UniProtKB.::GO:0010569; P:regulation of double-strand break repair via homologous recombination; ISS:UniProtKB. | 145 | Q7UFQ9 | 239 | NPD_RHOBA NAD-dependent protein deacylase OS=... | 127 | 0.000002 | 52.8 | 30 | 47 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro. | 146 | Q5WKC8 | 237 | NPD_BACSK NAD-dependent protein deacetylase O... | 138 | 0.000003 | 52 | 30 | 49 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro. | 147 | Q87PH8 | 241 | NPD_VIBPA NAD-dependent protein deacylase OS=... | 126 | 0.000004 | 51.6 | 30 | 45 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro. | 148 | B5YJW3 | 256 | NPD_THEYD NAD-dependent protein deacetylase O... | 138 | 0.000004 | 51.6 | 32 | 47 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro. | 149 | Q5HU51 | 233 | NPD_CAMJR NAD-dependent protein deacylase OS=... | 153 | 0.000008 | 50.4 | 31 | 46 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro. | 150 | B0RM75 | 293 | NPD_XANCB NAD-dependent protein deacetylase O... | 141 | 0.000009 | 50.8 | 27 | 44 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro. | 151 | Q885X7 | 248 | NPD2_PSESM NAD-dependent protein deacylase 2 ... | 137 | 0.00001 | 50.4 | 28 | 41 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro. |
