Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Candida albicans WO1
Locus:
CAWG_00515
Length:
385
Number of sequences:
5931
Description:
conserved hypothetical protein
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
91Q08509    821   EPS8_MOUSE Epidermal growth factor receptor k...580.003     43.5     34     59GO:0017146; C:N-methyl-D-aspartate selective glutamate receptor complex; IDA:MGI.::GO:0014069; C:postsynaptic density; IDA:MGI.::GO:0019717; C:synaptosome; IDA:MGI.
GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0031532; P:actin cytoskeleton reorganization; IMP:MGI.::GO:0051017; P:actin filament bundle assembly; IGI:MGI.::GO:0008344; P:adult locomotory behavior; IMP:MGI.::GO:0048149; P:behavioral response to ethanol; IMP:MGI.
92O43639    380   NCK2_HUMAN Cytoplasmic protein NCK2 OS=Homo s...510.52     35.8     37     51GO:0005829; C:cytosol; TAS:Reactome.::GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.
GO:0008093; F:cytoskeletal adaptor activity; NAS:UniProtKB.::GO:0030159; F:receptor signaling complex scaffold activity; NAS:UniProtKB.
GO:0007411; P:axon guidance; TAS:Reactome.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:ProtInc.::GO:0008285; P:negative regulation of cell proliferation; TAS:ProtInc.::GO:0030838; P:positive regulation of actin filament polymerization; IMP:UniProtKB.::GO:0042102; P:positive regulation of T cell proliferation; IMP:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0007176; P:regulation of epidermal growth factor-activated receptor activity; TAS:ProtInc.::GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.::GO:0007172; P:signal complex assembly; NAS:UniProtKB.::GO:0042110; P:T cell activation; NAS:UniProtKB.
93Q9QY17    488   PACN2_RAT Protein kinase C and casein kinase ...700.003     43.1     37     60GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:IntAct.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
94Q9DDA9    477   PACN2_XENLA Protein kinase C and casein kinas...600.003     43.1     37     63GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
95Q9V9J3    517   SRC42_DROME Tyrosine-protein kinase Src42A OS...570.004     42.7     46     58
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.
GO:0051017; P:actin filament bundle assembly; IMP:FlyBase.::GO:0043277; P:apoptotic cell clearance; IMP:FlyBase.::GO:0048749; P:compound eye development; IMP:FlyBase.::GO:0007395; P:dorsal closure, spreading of leading edge cells; IMP:FlyBase.::GO:0046529; P:imaginal disc fusion, thorax closure; IMP:FlyBase.::GO:0007476; P:imaginal disc-derived wing morphogenesis; IMP:FlyBase.::GO:0007254; P:JNK cascade; TAS:FlyBase.::GO:0042059; P:negative regulation of epidermal growth factor receptor signaling pathway; IGI:FlyBase.::GO:0007424; P:open tracheal system development; IMP:FlyBase.::GO:0018108; P:peptidyl-tyrosine phosphorylation; IMP:FlyBase.::GO:0007435; P:salivary gland morphogenesis; IMP:FlyBase.::GO:0007169; P:transmembrane receptor protein tyrosine kinase signaling pathway; IGI:FlyBase.::GO:0006099; P:tricarboxylic acid cycle; IDA:FlyBase.
96P09769    529   FGR_HUMAN Tyrosine-protein kinase Fgr OS=Homo...690.004     42.7     36     61GO:0005829; C:cytosol; TAS:Reactome.::GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.::GO:0005758; C:mitochondrial intermembrane space; IEA:UniProtKB-SubCell.::GO:0032587; C:ruffle membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0034988; F:Fc-gamma receptor I complex binding; IDA:UniProtKB.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IDA:UniProtKB.::GO:0001784; F:phosphotyrosine binding; ISS:UniProtKB.::GO:0019901; F:protein kinase binding; ISS:UniProtKB.
GO:0007596; P:blood coagulation; TAS:Reactome.::GO:0050830; P:defense response to Gram-positive bacterium; ISS:UniProtKB.::GO:0002768; P:immune response-regulating cell surface receptor signaling pathway; TAS:UniProtKB.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW.::GO:0007229; P:integrin-mediated signaling pathway; IMP:UniProtKB.::GO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:UniProtKB.::GO:0030335; P:positive regulation of cell migration; ISS:UniProtKB.::GO:0050715; P:positive regulation of cytokine secretion; ISS:UniProtKB.::GO:0043306; P:positive regulation of mast cell degranulation; ISS:UniProtKB.::GO:0043552; P:positive regulation of phosphatidylinositol 3-kinase activity; IMP:UniProtKB.::GO:0014068; P:positive regulation of phosphatidylinositol 3-kinase cascade; IMP:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:0008360; P:regulation of cell shape; ISS:UniProtKB.::GO:0045088; P:regulation of innate immune response; ISS:UniProtKB.::GO:0050764; P:regulation of phagocytosis; ISS:UniProtKB.::GO:0045859; P:regulation of protein kinase activity; ISS:UniProtKB.::GO:0009615; P:response to virus; TAS:ProtInc.
97Q62418    436   DBNL_MOUSE Drebrin-like protein OS=Mus muscul...570.004     42.7     39     61GO:0005938; C:cell cortex; IDA:MGI.::GO:0030027; C:lamellipodium; IDA:UniProtKB.::GO:0001726; C:ruffle; IDA:UniProtKB.
GO:0051015; F:actin filament binding; IDA:UniProtKB.::GO:0019904; F:protein domain specific binding; IDA:MGI.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0016601; P:Rac protein signal transduction; IDA:MGI.
98P09324    541   YES_CHICK Tyrosine-protein kinase Yes OS=Gall...570.004     42.7     42     61GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.
99P46109    303   CRKL_HUMAN Crk-like protein OS=Homo sapiens (...560.005     42     36     57GO:0005829; C:cytosol; TAS:Reactome.
GO:0005070; F:SH3/SH2 adaptor activity; TAS:ProtInc.::GO:0004871; F:signal transducer activity; TAS:ProtInc.
GO:0007254; P:JNK cascade; TAS:ProtInc.::GO:0007265; P:Ras protein signal transduction; TAS:ProtInc.
100Q9JHL4    436   DBNL_RAT Drebrin-like protein OS=Rattus norve...570.005     42.4     39     61GO:0005938; C:cell cortex; ISS:UniProtKB.::GO:0030027; C:lamellipodium; ISS:UniProtKB.::GO:0014069; C:postsynaptic density; IDA:RGD.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0016601; P:Rac protein signal transduction; ISS:UniProtKB.
101A6H7G2    423   DBNL_BOVIN Drebrin-like protein OS=Bos taurus...570.005     42.4     39     61GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
102Q9UJU6    430   DBNL_HUMAN Drebrin-like protein OS=Homo sapie...570.006     42     39     61GO:0005938; C:cell cortex; ISS:UniProtKB.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0030027; C:lamellipodium; ISS:UniProtKB.
GO:0003779; F:actin binding; ISS:UniProtKB.::GO:0008047; F:enzyme activator activity; TAS:ProtInc.
GO:0007257; P:activation of JUN kinase activity; TAS:ProtInc.::GO:0006921; P:cellular component disassembly involved in apoptotic process; TAS:Reactome.::GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0016601; P:Rac protein signal transduction; ISS:UniProtKB.
103Q02977    536   YRK_CHICK Proto-oncogene tyrosine-protein kin...690.007     42     39     59
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.
104P00527    528   YES_AVISY Tyrosine-protein kinase transformin...1030.007     42     32     50
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.
105P42522    1182   MYOC_DICDI Myosin IC heavy chain OS=Dictyoste...540.007     42.4     39     61GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.::GO:0016459; C:myosin complex; IEA:UniProtKB-KW.::GO:0097203; C:phagocytic cup lip; IDA:dictyBase.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003774; F:motor activity; IEA:InterPro.
GO:0006935; P:chemotaxis; IEA:UniProtKB-KW.::GO:0006909; P:phagocytosis; IMP:dictyBase.
106P34109    1109   MYOD_DICDI Myosin ID heavy chain OS=Dictyoste...560.007     42.4     45     61GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0031252; C:cell leading edge; IDA:dictyBase.::GO:0016459; C:myosin complex; IEA:UniProtKB-KW.::GO:0031143; C:pseudopodium; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003774; F:motor activity; IEA:InterPro.
GO:0006935; P:chemotaxis; IEA:UniProtKB-KW.::GO:0006909; P:phagocytosis; IEA:UniProtKB-KW.
107A7E8B6    1150   SLA1_SCLS1 Actin cytoskeleton-regulatory comp...550.026     40.4     40     55GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0042802; F:identical protein binding; IEA:InterPro.::GO:0030674; F:protein binding, bridging; IEA:InterPro.::GO:0043130; F:ubiquitin binding; IEA:InterPro.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
108Q5R4H4    822   EPS8_PONAB Epidermal growth factor receptor k...560.008     42     36     59
109Q12929    822   EPS8_HUMAN Epidermal growth factor receptor k...560.008     42     36     59
GO:0005070; F:SH3/SH2 adaptor activity; TAS:ProtInc.
GO:0008283; P:cell proliferation; TAS:ProtInc.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:ProtInc.
110P70297    548   STAM1_MOUSE Signal transducing adapter molecu...540.008     42     43     61GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:MGI.
GO:0006886; P:intracellular protein transport; IEA:InterPro.
111O88811    523   STAM2_MOUSE Signal transducing adapter molecu...710.009     41.6     34     52GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.
GO:0006886; P:intracellular protein transport; IEA:InterPro.
112P15891    592   ABP1_YEAST Actin-binding protein OS=Saccharom...560.009     41.6     43     61GO:0030479; C:actin cortical patch; IDA:SGD.::GO:0043332; C:mating projection tip; IDA:SGD.
GO:0051015; F:actin filament binding; IDA:SGD.
GO:0000147; P:actin cortical patch assembly; IMP:SGD.::GO:0008104; P:protein localization; IMP:SGD.
113Q92266    380   PEX13_PICPA Peroxisomal membrane protein PEX1...630.009     41.6     25     57GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005778; C:peroxisomal membrane; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0016560; P:protein import into peroxisome matrix, docking; IEA:InterPro.
114P47941    303   CRKL_MOUSE Crk-like protein OS=Mus musculus (...560.01     41.2     34     57
GO:0005515; F:protein binding; IPI:MGI.
GO:0009952; P:anterior/posterior pattern specification; IGI:MGI.::GO:0001568; P:blood vessel development; IGI:MGI.::GO:0007507; P:heart development; IGI:MGI.::GO:0009887; P:organ morphogenesis; IMP:MGI.::GO:0060017; P:parathyroid gland development; IGI:MGI.::GO:0048538; P:thymus development; IGI:MGI.
115Q60598    546   SRC8_MOUSE Src substrate cortactin OS=Mus mus...730.01     41.6     41     56GO:0005938; C:cell cortex; IDA:MGI.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IDA:UniProtKB.::GO:0001726; C:ruffle; IDA:UniProtKB.
GO:0005515; F:protein binding; IPI:UniProtKB.
116O93436    468   STAM2_CHICK Signal transducing adapter molecu...540.01     41.6     44     61GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.
GO:0006886; P:intracellular protein transport; IEA:InterPro.
117Q5U2U2    303   CRKL_RAT Crk-like protein OS=Rattus norvegicu...560.01     41.2     34     57
118Q06187    659   BTK_HUMAN Tyrosine-protein kinase BTK OS=Homo...530.011     41.6     40     57GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0045121; C:membrane raft; IDA:HGNC.::GO:0005634; C:nucleus; TAS:UniProtKB.::GO:0005886; C:plasma membrane; IDA:UniProtKB.
GO:0005524; F:ATP binding; TAS:HGNC.::GO:0042802; F:identical protein binding; IPI:IntAct.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; TAS:UniProtKB.::GO:0005547; F:phosphatidylinositol-3,4,5-trisphosphate binding; IDA:UniProtKB.
GO:0002250; P:adaptive immune response; TAS:UniProtKB.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0042113; P:B cell activation; TAS:UniProtKB.::GO:0050853; P:B cell receptor signaling pathway; TAS:UniProtKB.::GO:0019722; P:calcium-mediated signaling; TAS:HGNC.::GO:0008624; P:induction of apoptosis by extracellular signals; TAS:ProtInc.::GO:0045087; P:innate immune response; TAS:UniProtKB.::GO:0007498; P:mesoderm development; TAS:ProtInc.::GO:0045579; P:positive regulation of B cell differentiation; TAS:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; TAS:UniProtKB.::GO:0002902; P:regulation of B cell apoptotic process; TAS:UniProtKB.::GO:0002721; P:regulation of B cell cytokine production; TAS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
119P10686    1290   PLCG1_RAT 1-phosphatidylinositol 4,5-bisphosp...590.011     41.6     37     56GO:0030027; C:lamellipodium; ISS:UniProtKB.::GO:0005886; C:plasma membrane; TAS:Reactome.::GO:0001726; C:ruffle; ISS:UniProtKB.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005158; F:insulin receptor binding; IDA:RGD.::GO:0004435; F:phosphatidylinositol phospholipase C activity; IEA:EC.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0051219; F:phosphoprotein binding; IPI:RGD.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
GO:0006816; P:calcium ion transport; IMP:RGD.::GO:0071364; P:cellular response to epidermal growth factor stimulus; ISS:UniProtKB.::GO:0032959; P:inositol trisphosphate biosynthetic process; IMP:RGD.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0009395; P:phospholipid catabolic process; IEA:InterPro.::GO:0032236; P:positive regulation of calcium ion transport via store-operated calcium channel activity; IMP:RGD.::GO:0010634; P:positive regulation of epithelial cell migration; IMP:RGD.::GO:0009306; P:protein secretion; IMP:RGD.::GO:0009629; P:response to gravity; IEP:RGD.::GO:0042542; P:response to hydrogen peroxide; IEP:RGD.::GO:0043278; P:response to morphine; IEP:RGD.::GO:0010243; P:response to organic nitrogen; IEP:RGD.
120Q62077    1302   PLCG1_MOUSE 1-phosphatidylinositol 4,5-bispho...590.011     41.6     37     56GO:0005829; C:cytosol; TAS:Reactome.::GO:0030027; C:lamellipodium; ISS:UniProtKB.::GO:0001726; C:ruffle; ISS:UniProtKB.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0035254; F:glutamate receptor binding; IPI:MGI.::GO:0004435; F:phosphatidylinositol phospholipase C activity; IEA:EC.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0030971; F:receptor tyrosine kinase binding; IPI:UniProtKB.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
GO:0071364; P:cellular response to epidermal growth factor stimulus; ISS:UniProtKB.::GO:0001701; P:in utero embryonic development; IMP:MGI.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0009395; P:phospholipid catabolic process; IEA:InterPro.::GO:0010634; P:positive regulation of epithelial cell migration; ISS:UniProtKB.::GO:0050852; P:T cell receptor signaling pathway; IDA:MGI.
121P14317    486   HCLS1_HUMAN Hematopoietic lineage cell-specif...550.012     41.2     36     65GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0005886; C:plasma membrane; IDA:HPA.
GO:0003677; F:DNA binding; TAS:ProtInc.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
GO:0030218; P:erythrocyte differentiation; ISS:UniProtKB.::GO:0035556; P:intracellular signal transduction; TAS:ProtInc.::GO:0008284; P:positive regulation of cell proliferation; ISS:UniProtKB.::GO:0042531; P:positive regulation of tyrosine phosphorylation of STAT protein; ISS:UniProtKB.::GO:0009725; P:response to hormone stimulus; ISS:UniProtKB.
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