rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
61 | E3QNZ1 | 293 | SHO1_COLGM High osmolarity signaling protein ... | 151 | 2e-21 | 96.7 | 30 | 57 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006950; P:response to stress; IEA:UniProtKB-KW. | 62 | A2QGW1 | 288 | SHO1_ASPNC High osmolarity signaling protein ... | 149 | 1e-20 | 94 | 34 | 58 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006950; P:response to stress; IEA:UniProtKB-KW. | 63 | Q7SGL6 | 304 | SHO1_NEUCR High osmolarity signaling protein ... | 59 | 2e-20 | 94 | 63 | 83 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006950; P:response to stress; IEA:UniProtKB-KW. | 64 | E7RAI2 | 282 | SHO1_PICAD High osmolarity signaling protein ... | 55 | 0.0000000000001 | 74.3 | 49 | 75 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006950; P:response to stress; IEA:UniProtKB-KW. | 65 | Q5AVI2 | 287 | SHO1_EMENI High osmolarity signaling protein ... | 146 | 3e-20 | 92.8 | 33 | 56 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006950; P:response to stress; IEA:UniProtKB-KW. | 66 | D8PSG0 | 331 | SHO1_SCHCM High osmolarity signaling protein ... | 111 | 0.000007 | 50.8 | 24 | 51 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006950; P:response to stress; IEA:UniProtKB-KW. | 67 | Q4P9Q7 | 335 | SHO1_USTMA High osmolarity signaling protein ... | 118 | 0.000006 | 51.2 | 26 | 53 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006950; P:response to stress; IEA:UniProtKB-KW. | 68 | E7A253 | 343 | SHO1_SPORE High osmolarity signaling protein ... | 106 | 0.0000008 | 53.9 | 28 | 53 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006950; P:response to stress; IEA:UniProtKB-KW. | 69 | E6RET3 | 296 | SHO1_CRYGW High osmolarity signaling protein ... | 128 | 0.08 | 38.1 | 23 | 47 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006950; P:response to stress; IEA:UniProtKB-KW. | 70 | Q6GM14 | 376 | DBNLB_XENLA Drebrin-like protein B OS=Xenopus... | 81 | 0.00002 | 49.7 | 37 | 57 | GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW. | | | | | | | | | | | 71 | Q9P7E8 | 857 | APP1_SCHPO Protein app1 OS=Schizosaccharomyce... | 32 | 7.4 | 32.7 | 44 | 63 | GO:0030479; C:actin cortical patch; IDA:PomBase.::GO:0032153; C:cell division site; IDA:PomBase.::GO:0051286; C:cell tip; IDA:PomBase. | | | | | | | | | | GO:0003779; F:actin binding; IEA:InterPro. | | | | | | | | | | GO:0030036; P:actin cytoskeleton organization; IC:PomBase. | 72 | Q15811 | 1721 | ITSN1_HUMAN Intersectin-1 OS=Homo sapiens (Hu... | 56 | 0.22 | 37.4 | 36 | 57 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005905; C:coated pit; IDA:UniProtKB.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IDA:UniProtKB.::GO:0045202; C:synapse; IEA:UniProtKB-KW.::GO:0019717; C:synaptosome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005509; F:calcium ion binding; NAS:UniProtKB.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0070064; F:proline-rich region binding; IPI:UniProtKB.::GO:0032947; F:protein complex scaffold; IDA:UniProtKB.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0008624; P:induction of apoptosis by extracellular signals; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.::GO:0048488; P:synaptic vesicle endocytosis; TAS:ProtInc. | 73 | O55033 | 380 | NCK2_MOUSE Cytoplasmic protein NCK2 OS=Mus mu... | 51 | 0.47 | 36.2 | 37 | 51 | GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0012506; C:vesicle membrane; IDA:MGI. | | | | | | | | | | | | | | | | | | | | GO:0007015; P:actin filament organization; IMP:MGI.::GO:0016477; P:cell migration; IMP:MGI.::GO:0030032; P:lamellipodium assembly; IMP:MGI.::GO:0006417; P:regulation of translation; IEA:UniProtKB-KW. | 74 | Q9NZM3 | 1697 | ITSN2_HUMAN Intersectin-2 OS=Homo sapiens (Hu... | 55 | 0.56 | 36.2 | 40 | 55 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.::GO:0005070; F:SH3/SH2 adaptor activity; TAS:ProtInc. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro. | 75 | Q9Z0R4 | 1714 | ITSN1_MOUSE Intersectin-1 OS=Mus musculus (Mo... | 188 | 0.33 | 37 | 23 | 37 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0030139; C:endocytic vesicle; IDA:MGI.::GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IDA:MGI.::GO:0016020; C:membrane; IEA:UniProtKB-KW.::GO:0045202; C:synapse; IEA:UniProtKB-KW.::GO:0019717; C:synaptosome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0019209; F:kinase activator activity; IDA:MGI.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0043524; P:negative regulation of neuron apoptotic process; IMP:MGI.::GO:0051897; P:positive regulation of protein kinase B signaling cascade; IDA:MGI.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IDA:MGI. | 76 | Q9VU84 | 531 | DBNL_DROME Drebrin-like protein OS=Drosophila... | 57 | 0.0008 | 45.1 | 42 | 60 | GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IDA:UniProtKB. | | | | | | | | | | GO:0003779; F:actin binding; IC:UniProtKB. | | | | | | | | | | | 77 | Q8I7C3 | 657 | LASP1_DROME LIM and SH3 domain protein Lasp O... | 54 | 0.0009 | 45.1 | 41 | 63 | GO:0005925; C:focal adhesion; IDA:FlyBase.::GO:0070864; C:sperm individualization complex; IDA:FlyBase. | | | | | | | | | | GO:0003779; F:actin binding; IDA:FlyBase.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007279; P:pole cell formation; IMP:FlyBase.::GO:0045856; P:positive regulation of pole plasm oskar mRNA localization; IMP:FlyBase.::GO:0007291; P:sperm individualization; IMP:FlyBase. | 78 | Q99M51 | 377 | NCK1_MOUSE Cytoplasmic protein NCK1 OS=Mus mu... | 51 | 4.9 | 32.7 | 33 | 51 | GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0012506; C:vesicle membrane; IDA:MGI. | | | | | | | | | | GO:0019904; F:protein domain specific binding; IPI:MGI. | | | | | | | | | | GO:0007015; P:actin filament organization; IMP:MGI.::GO:0016477; P:cell migration; IMP:MGI.::GO:0030032; P:lamellipodium assembly; IMP:MGI.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0006417; P:regulation of translation; IEA:UniProtKB-KW. | 79 | Q9WVE9 | 1217 | ITSN1_RAT Intersectin-1 OS=Rattus norvegicus ... | 56 | 0.34 | 37 | 36 | 55 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-KW.::GO:0045202; C:synapse; IEA:UniProtKB-KW.::GO:0019717; C:synaptosome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0006887; P:exocytosis; TAS:RGD. | 80 | Q7ZXQ9 | 447 | DBNLA_XENLA Drebrin-like protein A OS=Xenopus... | 82 | 0.001 | 44.7 | 34 | 54 | GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW. | | | | | | | | | | | 81 | P16333 | 377 | NCK1_HUMAN Cytoplasmic protein NCK1 OS=Homo s... | 51 | 5.4 | 32.7 | 33 | 51 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; TAS:Reactome. | | | | | | | | | | GO:0008093; F:cytoskeletal adaptor activity; NAS:UniProtKB.::GO:0005102; F:receptor binding; IPI:UniProtKB.::GO:0030159; F:receptor signaling complex scaffold activity; NAS:UniProtKB. | | | | | | | | | | GO:0007411; P:axon guidance; TAS:Reactome.::GO:0030838; P:positive regulation of actin filament polymerization; IMP:UniProtKB.::GO:0042102; P:positive regulation of T cell proliferation; IMP:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.::GO:0007172; P:signal complex assembly; NAS:UniProtKB.::GO:0042110; P:T cell activation; IMP:UniProtKB.::GO:0050852; P:T cell receptor signaling pathway; TAS:Reactome. | 82 | Q5RC07 | 716 | ES8L2_PONAB Epidermal growth factor receptor ... | 52 | 0.001 | 44.7 | 40 | 60 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 83 | Q9H6S3 | 715 | ES8L2_HUMAN Epidermal growth factor receptor ... | 52 | 0.001 | 44.7 | 40 | 60 | GO:0005737; C:cytoplasm; IDA:HPA.::GO:0005886; C:plasma membrane; IDA:HPA. | | | | | | | | | | | | | | | | | | | | | 84 | Q99K30 | 729 | ES8L2_MOUSE Epidermal growth factor receptor ... | 51 | 0.001 | 44.7 | 41 | 61 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 85 | O75886 | 525 | STAM2_HUMAN Signal transducing adapter molecu... | 71 | 0.001 | 44.3 | 37 | 54 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:HPA. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0016044; P:cellular membrane organization; TAS:Reactome.::GO:0016197; P:endosome transport; TAS:Reactome.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0042059; P:negative regulation of epidermal growth factor receptor signaling pathway; TAS:Reactome. | 86 | Q9Z0R6 | 1659 | ITSN2_MOUSE Intersectin-2 OS=Mus musculus (Mo... | 55 | 0.27 | 37.4 | 40 | 55 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro. | 87 | Q9UNF0 | 486 | PACN2_HUMAN Protein kinase C and casein kinas... | 88 | 0.002 | 43.5 | 35 | 57 | GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005215; F:transporter activity; TAS:ProtInc. | | | | | | | | | | GO:0030036; P:actin cytoskeleton organization; TAS:ProtInc.::GO:0006897; P:endocytosis; IEA:UniProtKB-KW. | 88 | Q9WVE8 | 486 | PACN2_MOUSE Protein kinase C and casein kinas... | 101 | 0.002 | 43.5 | 31 | 53 | GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; IDA:MGI. | | | | | | | | | | GO:0008092; F:cytoskeletal protein binding; IDA:MGI. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0045806; P:negative regulation of endocytosis; IDA:MGI.::GO:0007165; P:signal transduction; TAS:MGI. | 89 | Q14247 | 550 | SRC8_HUMAN Src substrate cortactin OS=Homo sa... | 73 | 0.002 | 43.5 | 41 | 58 | GO:0005938; C:cell cortex; ISS:UniProtKB.::GO:0005856; C:cytoskeleton; TAS:ProtInc.::GO:0030027; C:lamellipodium; ISS:UniProtKB.::GO:0001726; C:ruffle; ISS:UniProtKB.::GO:0005625; C:soluble fraction; TAS:ProtInc. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | | 90 | O42287 | 1270 | ITSN1_XENLA Intersectin-1 OS=Xenopus laevis (... | 55 | 0.72 | 35.8 | 29 | 60 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-KW.::GO:0045202; C:synapse; IEA:UniProtKB-KW.::GO:0019717; C:synaptosome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW. | 91 | Q08509 | 821 | EPS8_MOUSE Epidermal growth factor receptor k... | 58 | 0.003 | 43.5 | 34 | 59 | GO:0017146; C:N-methyl-D-aspartate selective glutamate receptor complex; IDA:MGI.::GO:0014069; C:postsynaptic density; IDA:MGI.::GO:0019717; C:synaptosome; IDA:MGI. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0031532; P:actin cytoskeleton reorganization; IMP:MGI.::GO:0051017; P:actin filament bundle assembly; IGI:MGI.::GO:0008344; P:adult locomotory behavior; IMP:MGI.::GO:0048149; P:behavioral response to ethanol; IMP:MGI. |