Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Candida albicans WO1
Locus:
CAWG_00430
Length:
517
Number of sequences:
5931
Description:
hypothetical protein similar to negative regulator of iron uptake genes
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P40349    1084   URB1_USTMA Siderophore biosynthesis regulator...1975e-52     195     49     65GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
2Q10134    564   FEP1_SCHPO Iron-sensing transcription factor ...820.000000000001     73.6     43     56GO:0005634; C:nucleus; IDA:PomBase.
GO:0042803; F:protein homodimerization activity; IDA:PomBase.::GO:0000978; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding; IDA:PomBase.::GO:0000981; F:sequence-specific DNA binding RNA polymerase II transcription factor activity; NAS:PomBase.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006879; P:cellular iron ion homeostasis; TAS:PomBase.::GO:0090375; P:negative regulation of transcription from RNA polymerase II promoter in response to iron ion starvation; IMP:PomBase.::GO:0034756; P:regulation of iron ion transport; IMP:PomBase.
3Q92259    532   SREP_PENCH GATA factor SREP OS=Penicillium ch...2265e-40     156     43     54GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
4P52168    540   PNR_DROME GATA-binding factor A OS=Drosophila...880.0000000004     65.9     39     57GO:0005634; C:nucleus; IDA:FlyBase.
GO:0046982; F:protein heterodimerization activity; IPI:FlyBase.::GO:0000983; F:RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity; IDA:FlyBase.::GO:0001103; F:RNA polymerase II repressing transcription factor binding; IPI:FlyBase.::GO:0043565; F:sequence-specific DNA binding; IDA:FlyBase.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007350; P:blastoderm segmentation; IMP:FlyBase.::GO:0007510; P:cardioblast cell fate determination; IMP:FlyBase.::GO:0008407; P:chaeta morphogenesis; TAS:FlyBase.::GO:0007391; P:dorsal closure; TAS:FlyBase.::GO:0007398; P:ectoderm development; TAS:FlyBase.::GO:0035050; P:embryonic heart tube development; IMP:FlyBase.::GO:0060047; P:heart contraction; IMP:FlyBase.::GO:0048542; P:lymph gland development; IMP:FlyBase.::GO:0045892; P:negative regulation of transcription, DNA-dependent; TAS:FlyBase.::GO:0061320; P:pericardial nephrocyte differentiation; IMP:FlyBase.::GO:0042440; P:pigment metabolic process; IMP:FlyBase.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:FlyBase.::GO:0002805; P:regulation of antimicrobial peptide biosynthetic process; IMP:FlyBase.::GO:0007179; P:transforming growth factor beta receptor signaling pathway; TAS:FlyBase.
5P18494    730   GLN3_YEAST Nitrogen regulatory protein GLN3 O...420.0000000003     66.6     60     79GO:0005829; C:cytosol; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.
GO:0000978; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding; IDA:SGD.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:SGD.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0042128; P:nitrate assimilation; IEA:UniProtKB-KW.::GO:0001080; P:nitrogen catabolite activation of transcription from RNA polymerase II promoter; IMP:SGD.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:SGD.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
6P91623    486   GATAC_DROME GATA-binding factor C OS=Drosophi...1830.000000000000007     80.5     30     39GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IDA:FlyBase.::GO:0000981; F:sequence-specific DNA binding RNA polymerase II transcription factor activity; ISS:FlyBase.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0009887; P:organ morphogenesis; IMP:FlyBase.::GO:0009888; P:tissue development; IMP:FlyBase.
7P43695    390   GAT5A_XENLA GATA-binding factor 5-A OS=Xenopu...790.0000000006     64.7     39     57GO:0005634; C:nucleus; IDA:MGI.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0044212; F:transcription regulatory region DNA binding; IDA:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
8Q9HEV5    426   ASD4_NEUCR GATA type zinc finger protein asd-...540.00000004     59.3     46     63GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
9P23773    435   GATA3_XENLA GATA-binding factor 3 OS=Xenopus ...540.000000001     63.9     52     69GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
10P52172    1264   SRP_DROME Box A-binding factor OS=Drosophila ...450.000000008     62     56     71GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:FlyBase.::GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IDA:FlyBase.::GO:0043565; F:sequence-specific DNA binding; IDA:FlyBase.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0046665; P:amnioserosa maintenance; IMP:FlyBase.::GO:0001709; P:cell fate determination; TAS:FlyBase.::GO:0042688; P:crystal cell differentiation; TAS:FlyBase.::GO:0007391; P:dorsal closure; TAS:FlyBase.::GO:0035050; P:embryonic heart tube development; IMP:FlyBase.::GO:0035162; P:embryonic hemopoiesis; IMP:FlyBase.::GO:0001706; P:endoderm formation; TAS:FlyBase.::GO:0007503; P:fat body development; IEP:FlyBase.::GO:0008354; P:germ cell migration; IMP:FlyBase.::GO:0007390; P:germ-band shortening; IMP:FlyBase.::GO:0008258; P:head involution; NAS:FlyBase.::GO:0007516; P:hemocyte development; IMP:FlyBase.::GO:0035167; P:larval lymph gland hemopoiesis; IMP:FlyBase.::GO:0001710; P:mesodermal cell fate commitment; IMP:FlyBase.::GO:0007494; P:midgut development; TAS:FlyBase.::GO:0042690; P:negative regulation of crystal cell differentiation; TAS:FlyBase.::GO:0006911; P:phagocytosis, engulfment; IMP:FlyBase.::GO:0007435; P:salivary gland morphogenesis; IMP:FlyBase.
11P23772    443   GATA3_MOUSE Trans-acting T-cell-specific tran...540.0000000009     64.3     52     69GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0000987; F:core promoter proximal region sequence-specific DNA binding; ISS:UniProtKB.::GO:0070888; F:E-box binding; ISS:UniProtKB.::GO:0001158; F:enhancer sequence-specific DNA binding; IDA:UniProtKB.::GO:0005134; F:interleukin-2 receptor binding; IPI:MGI.::GO:0046983; F:protein dimerization activity; IDA:MGI.::GO:0001078; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription; ISS:UniProtKB.::GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IDA:MGI.::GO:0000979; F:RNA polymerase II core promoter sequence-specific DNA binding; IDA:MGI.::GO:0003713; F:transcription coactivator activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0003180; P:aortic valve morphogenesis; IMP:UniProtKB.::GO:0007411; P:axon guidance; IMP:MGI.::GO:0061290; P:canonical Wnt receptor signaling pathway involved in metanephric kidney development; IMP:UniProtKB.::GO:0003215; P:cardiac right ventricle morphogenesis; IMP:UniProtKB.::GO:0001709; P:cell fate determination; IDA:MGI.::GO:0048469; P:cell maturation; IMP:MGI.::GO:0071773; P:cellular response to BMP stimulus; IDA:MGI.::GO:0071353; P:cellular response to interleukin-4; IEP:UniProtKB.::GO:0048589; P:developmental growth; IMP:MGI.::GO:0035162; P:embryonic hemopoiesis; IMP:MGI.::GO:0030218; P:erythrocyte differentiation; IDA:MGI.::GO:0006959; P:humoral immune response; IMP:MGI.::GO:0001701; P:in utero embryonic development; IMP:MGI.::GO:0042472; P:inner ear morphogenesis; IMP:MGI.::GO:0072643; P:interferon-gamma secretion; IMP:MGI.::GO:0072602; P:interleukin-4 secretion; IMP:MGI.::GO:0002088; P:lens development in camera-type eye; IMP:MGI.::GO:0072676; P:lymphocyte migration; ISS:UniProtKB.::GO:0008584; P:male gonad development; IMP:UniProtKB.::GO:0060374; P:mast cell differentiation; IDA:MGI.::GO:0060231; P:mesenchymal to epithelial transition; ISS:UniProtKB.::GO:0001823; P:mesonephros development; IMP:MGI.::GO:0045786; P:negative regulation of cell cycle; ISS:UniProtKB.::GO:2000146; P:negative regulation of cell motility; ISS:UniProtKB.::GO:2000607; P:negative regulation of cell proliferation involved in mesonephros development; IMP:UniProtKB.::GO:2000352; P:negative regulation of endothelial cell apoptotic process; ISS:UniProtKB.::GO:0045599; P:negative regulation of fat cell differentiation; ISS:UniProtKB.::GO:2000703; P:negative regulation of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation; IMP:UniProtKB.::GO:2000734; P:negative regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation; IMP:UniProtKB.::GO:0050728; P:negative regulation of inflammatory response; ISS:UniProtKB.::GO:0032689; P:negative regulation of interferon-gamma production; IDA:MGI.::GO:0032703; P:negative regulation of interleukin-2 production; IDA:MGI.::GO:0072179; P:nephric duct formation; IMP:UniProtKB.::GO:0001764; P:neuron migration; IMP:MGI.::GO:0042421; P:norepinephrine biosynthetic process; IMP:MGI.::GO:0071599; P:otic vesicle development; IMP:MGI.::GO:0060017; P:parathyroid gland development; IMP:MGI.::GO:0035898; P:parathyroid hormone secretion; IMP:MGI.::GO:0060037; P:pharyngeal system development; IMP:UniProtKB.::GO:0014065; P:phosphatidylinositol 3-kinase cascade; IMP:UniProtKB.::GO:0010595; P:positive regulation of endothelial cell migration; ISS:UniProtKB.::GO:0032736; P:positive regulation of interleukin-13 production; IMP:MGI.::GO:2000667; P:positive regulation of interleukin-13 secretion; ISS:UniProtKB.::GO:0032753; P:positive regulation of interleukin-4 production; IDA:MGI.::GO:0032754; P:positive regulation of interleukin-5 production; IMP:MGI.::GO:2000664; P:positive regulation of interleukin-5 secretion; ISS:UniProtKB.::GO:0051897; P:positive regulation of protein kinase B signaling cascade; ISS:UniProtKB.::GO:0045582; P:positive regulation of T cell differentiation; IDA:UniProtKB.::GO:2000611; P:positive regulation of thyroid hormone generation; ISS:UniProtKB.::GO:2000679; P:positive regulation of transcription regulatory region DNA binding; IMP:UniProtKB.::GO:0072107; P:positive regulation of ureteric bud formation; IMP:UniProtKB.::GO:0009791; P:post-embryonic development; IMP:MGI.::GO:0002572; P:pro-T cell differentiation; IMP:MGI.::GO:0043370; P:regulation of CD4-positive, alpha-beta T cell differentiation; IMP:MGI.::GO:2000683; P:regulation of cellular response to X-ray; ISS:UniProtKB.::GO:0042035; P:regulation of cytokine biosynthetic process; IDA:MGI.::GO:2000114; P:regulation of establishment of cell polarity; IDA:MGI.::GO:0061085; P:regulation of histone H3-K27 methylation; IDA:MGI.::GO:0051569; P:regulation of histone H3-K4 methylation; IDA:MGI.::GO:0072182; P:regulation of nephron tubule epithelial cell differentiation; IMP:UniProtKB.::GO:0043523; P:regulation of neuron apoptotic process; IMP:MGI.::GO:0048485; P:sympathetic nervous system development; IMP:MGI.::GO:0050852; P:T cell receptor signaling pathway; IDA:UniProtKB.::GO:0045064; P:T-helper 2 cell differentiation; IDA:MGI.::GO:0045061; P:thymic T cell selection; IMP:MGI.::GO:0048538; P:thymus development; IMP:MGI.::GO:0031929; P:TOR signaling cascade; IMP:UniProtKB.::GO:0035799; P:ureter maturation; IMP:MGI.::GO:0060676; P:ureteric bud formation; IMP:UniProtKB.::GO:0060065; P:uterus development; IMP:UniProtKB.::GO:0003281; P:ventricular septum development; IMP:UniProtKB.
12P23825    444   GATA3_CHICK GATA-binding factor 3 OS=Gallus g...540.000000001     64.3     52     69GO:0000790; C:nuclear chromatin; ISS:UniProtKB.
GO:0000987; F:core promoter proximal region sequence-specific DNA binding; ISS:UniProtKB.::GO:0070888; F:E-box binding; ISS:UniProtKB.::GO:0005515; F:protein binding; IPI:BHF-UCL.::GO:0001078; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription; ISS:UniProtKB.::GO:0003713; F:transcription coactivator activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0003180; P:aortic valve morphogenesis; ISS:UniProtKB.::GO:0042491; P:auditory receptor cell differentiation; IEP:UniProtKB.::GO:0007411; P:axon guidance; NAS:UniProtKB.::GO:0061290; P:canonical Wnt receptor signaling pathway involved in metanephric kidney development; ISS:UniProtKB.::GO:0003215; P:cardiac right ventricle morphogenesis; ISS:UniProtKB.::GO:0001709; P:cell fate determination; ISS:UniProtKB.::GO:0072676; P:lymphocyte migration; ISS:UniProtKB.::GO:0008584; P:male gonad development; ISS:UniProtKB.::GO:0060231; P:mesenchymal to epithelial transition; ISS:UniProtKB.::GO:0001823; P:mesonephros development; ISS:UniProtKB.::GO:0045786; P:negative regulation of cell cycle; ISS:UniProtKB.::GO:2000146; P:negative regulation of cell motility; ISS:UniProtKB.::GO:2000607; P:negative regulation of cell proliferation involved in mesonephros development; ISS:UniProtKB.::GO:2000352; P:negative regulation of endothelial cell apoptotic process; ISS:UniProtKB.::GO:0045599; P:negative regulation of fat cell differentiation; ISS:UniProtKB.::GO:2000703; P:negative regulation of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation; ISS:UniProtKB.::GO:2000734; P:negative regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation; ISS:UniProtKB.::GO:0050728; P:negative regulation of inflammatory response; ISS:UniProtKB.::GO:0072179; P:nephric duct formation; ISS:UniProtKB.::GO:0042421; P:norepinephrine biosynthetic process; ISS:UniProtKB.::GO:0060037; P:pharyngeal system development; ISS:UniProtKB.::GO:0014065; P:phosphatidylinositol 3-kinase cascade; ISS:UniProtKB.::GO:0010595; P:positive regulation of endothelial cell migration; ISS:UniProtKB.::GO:2000667; P:positive regulation of interleukin-13 secretion; ISS:UniProtKB.::GO:0032753; P:positive regulation of interleukin-4 production; ISS:UniProtKB.::GO:2000664; P:positive regulation of interleukin-5 secretion; ISS:UniProtKB.::GO:0051897; P:positive regulation of protein kinase B signaling cascade; ISS:UniProtKB.::GO:0045582; P:positive regulation of T cell differentiation; ISS:UniProtKB.::GO:2000611; P:positive regulation of thyroid hormone generation; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:2000679; P:positive regulation of transcription regulatory region DNA binding; ISS:UniProtKB.::GO:0072107; P:positive regulation of ureteric bud formation; ISS:UniProtKB.::GO:2000683; P:regulation of cellular response to X-ray; ISS:UniProtKB.::GO:0042035; P:regulation of cytokine biosynthetic process; ISS:UniProtKB.::GO:0072182; P:regulation of nephron tubule epithelial cell differentiation; ISS:UniProtKB.::GO:0048485; P:sympathetic nervous system development; ISS:UniProtKB.::GO:0050852; P:T cell receptor signaling pathway; ISS:UniProtKB.::GO:0031929; P:TOR signaling cascade; ISS:UniProtKB.::GO:0060676; P:ureteric bud formation; ISS:UniProtKB.::GO:0060065; P:uterus development; ISS:UniProtKB.::GO:0003281; P:ventricular septum development; ISS:UniProtKB.
13P43696    388   GAT5B_XENLA GATA-binding factor 5-B OS=Xenopu...570.000000002     62.8     46     67GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0045893; P:positive regulation of transcription, DNA-dependent; IEA:InterPro.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
14P70005    391   GAT6B_XENLA GATA-binding factor 6-B OS=Xenopu...1780.00000000000006     77     31     40GO:0005634; C:nucleus; IC:UniProtKB.
GO:0043565; F:sequence-specific DNA binding; IDA:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0035051; P:cardiac cell differentiation; IMP:UniProtKB.::GO:0048738; P:cardiac muscle tissue development; IMP:BHF-UCL.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
15P43693    387   GATA6_CHICK Transcription factor GATA-6 OS=Ga...1790.00000000000006     77     30     40
GO:0008270; F:zinc ion binding; IEA:InterPro.
16Q91428    438   GATA3_DANRE Transcription factor GATA-3 OS=Da...600.0000000009     64.3     50     65GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0021514; P:ventral spinal cord interneuron differentiation; IMP:ZFIN.
17Q91678    391   GAT6A_XENLA GATA-binding factor 6-A OS=Xenopu...1780.00000000000008     76.6     30     40GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0045893; P:positive regulation of transcription, DNA-dependent; IEA:InterPro.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
18Q95JA5    451   GATA6_PIG Transcription factor GATA-6 OS=Sus ...1050.0000000000001     76.3     39     61GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0045893; P:positive regulation of transcription, DNA-dependent; IEA:InterPro.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
19P23824    466   GATA2_CHICK GATA-binding factor 2 OS=Gallus g...1790.0000000000001     76.6     29     39GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
20Q924Y4    480   GATA2_RAT Endothelial transcription factor GA...1790.0000000000002     75.9     29     39GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006909; P:phagocytosis; IDA:RGD.::GO:0050766; P:positive regulation of phagocytosis; IDA:UniProtKB.
21P52167    508   GATAB_BOMMO Transcription factor BCFI OS=Bomb...1960.0000000000003     75.5     27     38GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
22O09100    480   GATA2_MOUSE Endothelial transcription factor ...1790.0000000000003     75.5     29     39GO:0005634; C:nucleus; IDA:MGI.::GO:0043234; C:protein complex; IDA:MGI.
GO:0003682; F:chromatin binding; IDA:MGI.::GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IDA:MGI.::GO:0000980; F:RNA polymerase II distal enhancer sequence-specific DNA binding; IDA:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0021533; P:cell differentiation in hindbrain; IMP:MGI.::GO:0001709; P:cell fate determination; IDA:MGI.::GO:0048469; P:cell maturation; IMP:MGI.::GO:0021954; P:central nervous system neuron development; IMP:MGI.::GO:0060216; P:definitive hemopoiesis; IMP:MGI.::GO:0001892; P:embryonic placenta development; IMP:MGI.::GO:0048873; P:homeostasis of number of cells within a tissue; IMP:MGI.::GO:0042472; P:inner ear morphogenesis; IMP:MGI.::GO:0045599; P:negative regulation of fat cell differentiation; IMP:MGI.::GO:0045650; P:negative regulation of macrophage differentiation; IDA:MGI.::GO:2000178; P:negative regulation of neural precursor cell proliferation; IMP:MGI.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:MGI.::GO:0048663; P:neuron fate commitment; IMP:MGI.::GO:0006909; P:phagocytosis; IEA:UniProtKB-KW.::GO:0021983; P:pituitary gland development; IMP:MGI.::GO:0045766; P:positive regulation of angiogenesis; IMP:MGI.::GO:0045648; P:positive regulation of erythrocyte differentiation; IDA:MGI.::GO:0045654; P:positive regulation of megakaryocyte differentiation; IDA:MGI.::GO:0050766; P:positive regulation of phagocytosis; ISS:UniProtKB.::GO:0035065; P:regulation of histone acetylation; IDA:MGI.::GO:0060872; P:semicircular canal development; IMP:MGI.::GO:0035019; P:somatic stem cell maintenance; IMP:MGI.::GO:0001655; P:urogenital system development; IMP:MGI.::GO:0021514; P:ventral spinal cord interneuron differentiation; IMP:MGI.
23P23769    480   GATA2_HUMAN Endothelial transcription factor ...1790.0000000000003     75.5     29     39GO:0005654; C:nucleoplasm; TAS:Reactome.
GO:0070742; F:C2H2 zinc finger domain binding; IPI:BHF-UCL.::GO:0003682; F:chromatin binding; IDA:MGI.::GO:0008134; F:transcription factor binding; IPI:BHF-UCL.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007596; P:blood coagulation; TAS:Reactome.::GO:0035854; P:eosinophil fate commitment; IDA:BHF-UCL.::GO:0045599; P:negative regulation of fat cell differentiation; IMP:UniProtKB.::GO:0070345; P:negative regulation of fat cell proliferation; IMP:UniProtKB.::GO:2000178; P:negative regulation of neural precursor cell proliferation; IDA:MGI.::GO:0045746; P:negative regulation of Notch signaling pathway; IDA:MGI.::GO:0006909; P:phagocytosis; IEA:UniProtKB-KW.::GO:0045766; P:positive regulation of angiogenesis; IDA:MGI.::GO:0050766; P:positive regulation of phagocytosis; ISS:UniProtKB.
24P23771    443   GATA3_HUMAN Trans-acting T-cell-specific tran...610.0000000005     65.1     49     64GO:0000790; C:nuclear chromatin; IDA:BHF-UCL.::GO:0005730; C:nucleolus; IDA:HPA.::GO:0005654; C:nucleoplasm; TAS:Reactome.
GO:0000987; F:core promoter proximal region sequence-specific DNA binding; IDA:UniProtKB.::GO:0001046; F:core promoter sequence-specific DNA binding; IDA:UniProtKB.::GO:0070888; F:E-box binding; IDA:BHF-UCL.::GO:0071837; F:HMG box domain binding; IPI:UniProtKB.::GO:0001078; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription; IMP:UniProtKB.::GO:0003713; F:transcription coactivator activity; IDA:UniProtKB.::GO:0008134; F:transcription factor binding; IPI:BHF-UCL.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0003180; P:aortic valve morphogenesis; ISS:UniProtKB.::GO:0007596; P:blood coagulation; TAS:Reactome.::GO:0061290; P:canonical Wnt receptor signaling pathway involved in metanephric kidney development; ISS:UniProtKB.::GO:0003215; P:cardiac right ventricle morphogenesis; ISS:UniProtKB.::GO:0001709; P:cell fate determination; ISS:UniProtKB.::GO:0035457; P:cellular response to interferon-alpha; IEP:UniProtKB.::GO:0071353; P:cellular response to interleukin-4; IEP:UniProtKB.::GO:0071356; P:cellular response to tumor necrosis factor; IEP:UniProtKB.::GO:0006952; P:defense response; TAS:ProtInc.::GO:0043583; P:ear development; IMP:UniProtKB.::GO:0072676; P:lymphocyte migration; IDA:UniProtKB.::GO:0008584; P:male gonad development; ISS:UniProtKB.::GO:0060231; P:mesenchymal to epithelial transition; IDA:UniProtKB.::GO:0001823; P:mesonephros development; ISS:UniProtKB.::GO:0045786; P:negative regulation of cell cycle; IMP:UniProtKB.::GO:2000146; P:negative regulation of cell motility; IMP:UniProtKB.::GO:2000607; P:negative regulation of cell proliferation involved in mesonephros development; ISS:UniProtKB.::GO:2000352; P:negative regulation of endothelial cell apoptotic process; IMP:UniProtKB.::GO:0045599; P:negative regulation of fat cell differentiation; IMP:UniProtKB.::GO:2000703; P:negative regulation of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation; ISS:UniProtKB.::GO:2000734; P:negative regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation; ISS:UniProtKB.::GO:0050728; P:negative regulation of inflammatory response; IMP:UniProtKB.::GO:0033600; P:negative regulation of mammary gland epithelial cell proliferation; IDA:UniProtKB.::GO:0072179; P:nephric duct formation; ISS:UniProtKB.::GO:0042421; P:norepinephrine biosynthetic process; ISS:UniProtKB.::GO:0060037; P:pharyngeal system development; ISS:UniProtKB.::GO:0014065; P:phosphatidylinositol 3-kinase cascade; ISS:UniProtKB.::GO:0010595; P:positive regulation of endothelial cell migration; IMP:UniProtKB.::GO:2000667; P:positive regulation of interleukin-13 secretion; IDA:UniProtKB.::GO:0032753; P:positive regulation of interleukin-4 production; ISS:UniProtKB.::GO:2000664; P:positive regulation of interleukin-5 secretion; IDA:UniProtKB.::GO:0051897; P:positive regulation of protein kinase B signaling cascade; IMP:UniProtKB.::GO:0045582; P:positive regulation of T cell differentiation; ISS:UniProtKB.::GO:2000611; P:positive regulation of thyroid hormone generation; IMP:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:2000679; P:positive regulation of transcription regulatory region DNA binding; IMP:UniProtKB.::GO:0072107; P:positive regulation of ureteric bud formation; ISS:UniProtKB.::GO:2000683; P:regulation of cellular response to X-ray; IMP:UniProtKB.::GO:0042035; P:regulation of cytokine biosynthetic process; ISS:UniProtKB.::GO:0072182; P:regulation of nephron tubule epithelial cell differentiation; ISS:UniProtKB.::GO:0043627; P:response to estrogen stimulus; IEP:UniProtKB.::GO:0009615; P:response to virus; IEP:UniProtKB.::GO:0048485; P:sympathetic nervous system development; ISS:UniProtKB.::GO:0050852; P:T cell receptor signaling pathway; ISS:UniProtKB.::GO:0031929; P:TOR signaling cascade; ISS:UniProtKB.::GO:0060676; P:ureteric bud formation; ISS:UniProtKB.::GO:0060065; P:uterus development; ISS:UniProtKB.::GO:0003281; P:ventricular septum development; ISS:UniProtKB.
25Q08DV0    443   GATA3_BOVIN Trans-acting T-cell-specific tran...610.0000000007     64.7     49     64GO:0000790; C:nuclear chromatin; ISS:UniProtKB.
GO:0000987; F:core promoter proximal region sequence-specific DNA binding; ISS:UniProtKB.::GO:0070888; F:E-box binding; ISS:UniProtKB.::GO:0001078; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription; ISS:UniProtKB.::GO:0003713; F:transcription coactivator activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0003180; P:aortic valve morphogenesis; ISS:UniProtKB.::GO:0061290; P:canonical Wnt receptor signaling pathway involved in metanephric kidney development; ISS:UniProtKB.::GO:0003215; P:cardiac right ventricle morphogenesis; ISS:UniProtKB.::GO:0001709; P:cell fate determination; ISS:UniProtKB.::GO:0072676; P:lymphocyte migration; ISS:UniProtKB.::GO:0008584; P:male gonad development; ISS:UniProtKB.::GO:0060231; P:mesenchymal to epithelial transition; ISS:UniProtKB.::GO:0001823; P:mesonephros development; ISS:UniProtKB.::GO:0045786; P:negative regulation of cell cycle; ISS:UniProtKB.::GO:2000146; P:negative regulation of cell motility; ISS:UniProtKB.::GO:2000607; P:negative regulation of cell proliferation involved in mesonephros development; ISS:UniProtKB.::GO:2000352; P:negative regulation of endothelial cell apoptotic process; ISS:UniProtKB.::GO:0045599; P:negative regulation of fat cell differentiation; ISS:UniProtKB.::GO:2000703; P:negative regulation of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation; ISS:UniProtKB.::GO:2000734; P:negative regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation; ISS:UniProtKB.::GO:0050728; P:negative regulation of inflammatory response; ISS:UniProtKB.::GO:0072179; P:nephric duct formation; ISS:UniProtKB.::GO:0042421; P:norepinephrine biosynthetic process; ISS:UniProtKB.::GO:0060037; P:pharyngeal system development; ISS:UniProtKB.::GO:0014065; P:phosphatidylinositol 3-kinase cascade; ISS:UniProtKB.::GO:0010595; P:positive regulation of endothelial cell migration; ISS:UniProtKB.::GO:2000667; P:positive regulation of interleukin-13 secretion; ISS:UniProtKB.::GO:0032753; P:positive regulation of interleukin-4 production; ISS:UniProtKB.::GO:2000664; P:positive regulation of interleukin-5 secretion; ISS:UniProtKB.::GO:0051897; P:positive regulation of protein kinase B signaling cascade; ISS:UniProtKB.::GO:0045582; P:positive regulation of T cell differentiation; ISS:UniProtKB.::GO:2000611; P:positive regulation of thyroid hormone generation; ISS:UniProtKB.::GO:2000679; P:positive regulation of transcription regulatory region DNA binding; ISS:UniProtKB.::GO:0072107; P:positive regulation of ureteric bud formation; ISS:UniProtKB.::GO:2000683; P:regulation of cellular response to X-ray; ISS:UniProtKB.::GO:0042035; P:regulation of cytokine biosynthetic process; ISS:UniProtKB.::GO:0072182; P:regulation of nephron tubule epithelial cell differentiation; ISS:UniProtKB.::GO:0048485; P:sympathetic nervous system development; ISS:UniProtKB.::GO:0050852; P:T cell receptor signaling pathway; ISS:UniProtKB.::GO:0031929; P:TOR signaling cascade; ISS:UniProtKB.::GO:0060676; P:ureteric bud formation; ISS:UniProtKB.::GO:0060065; P:uterus development; ISS:UniProtKB.::GO:0003281; P:ventricular septum development; ISS:UniProtKB.
26O94720    557   YCF8_SCHPO GATA zinc finger domain-containing...400.0000001     58.2     58     70GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
GO:0000978; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding; NAS:PomBase.::GO:0000981; F:sequence-specific DNA binding RNA polymerase II transcription factor activity; NAS:PomBase.::GO:0008270; F:zinc ion binding; IEA:InterPro.
27P23770    452   GATA2_XENLA GATA-binding factor 2 OS=Xenopus ...1790.0000000000006     74.3     28     39GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
28P42944    551   GZF3_YEAST Protein GZF3 OS=Saccharomyces cere...410.0000002     57     51     71GO:0005634; C:nucleus; IDA:SGD.
GO:0043565; F:sequence-specific DNA binding; IDA:SGD.::GO:0000981; F:sequence-specific DNA binding RNA polymerase II transcription factor activity; IMP:SGD.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0051457; P:maintenance of protein location in nucleus; IPI:SGD.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:SGD.::GO:0090295; P:nitrogen catabolite repression of transcription; IMP:SGD.
29P28515    416   ELT1_CAEEL Transcription factor elt-1 OS=Caen...540.0000002     57     43     61GO:0005634; C:nucleus; IDA:WormBase.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0000981; F:sequence-specific DNA binding RNA polymerase II transcription factor activity; IDA:WormBase.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0010171; P:body morphogenesis; IMP:WormBase.::GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0009957; P:epidermal cell fate specification; IMP:WormBase.::GO:0040011; P:locomotion; IMP:WormBase.::GO:0002009; P:morphogenesis of an epithelium; IMP:WormBase.::GO:0018991; P:oviposition; IMP:WormBase.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:WormBase.::GO:0007283; P:spermatogenesis; IMP:WormBase.
30Q61169    589   GATA6_MOUSE Transcription factor GATA-6 OS=Mu...1050.000000000001     73.9     36     56GO:0005667; C:transcription factor complex; IDA:MGI.
GO:0003682; F:chromatin binding; IDA:MGI.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IDA:MGI.::GO:0001103; F:RNA polymerase II repressing transcription factor binding; IPI:BHF-UCL.::GO:0043565; F:sequence-specific DNA binding; IDA:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006915; P:apoptotic process; IMP:MGI.::GO:0055007; P:cardiac muscle cell differentiation; IEP:BHF-UCL.::GO:0071773; P:cellular response to BMP stimulus; IDA:MGI.::GO:0071371; P:cellular response to gonadotropin stimulus; IDA:MGI.::GO:0060486; P:Clara cell differentiation; IGI:MGI.::GO:0007493; P:endodermal cell fate determination; IDA:MGI.::GO:0001701; P:in utero embryonic development; IMP:MGI.::GO:0001889; P:liver development; IMP:MGI.::GO:0060430; P:lung saccule development; IGI:MGI.::GO:0048645; P:organ formation; IMP:MGI.::GO:0003310; P:pancreatic A cell differentiation; IMP:MGI.::GO:0006644; P:phospholipid metabolic process; IGI:MGI.::GO:0060045; P:positive regulation of cardiac muscle cell proliferation; IGI:MGI.::GO:0051891; P:positive regulation of cardioblast differentiation; IEP:BHF-UCL.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.::GO:0043627; P:response to estrogen stimulus; IDA:MGI.::GO:0035239; P:tube morphogenesis; IGI:MGI.::GO:0003309; P:type B pancreatic cell differentiation; IMP:MGI.::GO:0060510; P:Type II pneumocyte differentiation; IGI:MGI.
31Q92908    595   GATA6_HUMAN Transcription factor GATA-6 OS=Ho...1070.000000000002     73.6     37     57
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.::GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007596; P:blood coagulation; TAS:Reactome.::GO:0060947; P:cardiac vascular smooth muscle cell differentiation; IMP:UniProtKB.::GO:0071456; P:cellular response to hypoxia; IDA:UniProtKB.::GO:0060575; P:intestinal epithelial cell differentiation; IDA:MGI.::GO:0008584; P:male gonad development; IEP:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0032911; P:negative regulation of transforming growth factor beta1 production; IMP:UniProtKB.::GO:0032912; P:negative regulation of transforming growth factor beta2 production; IMP:UniProtKB.::GO:0003148; P:outflow tract septum morphogenesis; IMP:BHF-UCL.::GO:0045766; P:positive regulation of angiogenesis; IDA:UniProtKB.::GO:0071158; P:positive regulation of cell cycle arrest; IDA:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0042493; P:response to drug; IMP:UniProtKB.
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