| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | P40555 | 220 | PSMD9_YEAST Probable 26S proteasome regulator... | 196 | 1e-26 | 107 | 34 | 56 | GO:0005829; C:cytosol; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0070682; P:proteasome regulatory particle assembly; IDA:SGD. | 2 | Q3SZ19 | 221 | PSMD9_BOVIN 26S proteasome non-ATPase regulat... | 192 | 2e-23 | 98.6 | 31 | 56 | | | | | | | | | | | | | | | | | | | | | GO:0070682; P:proteasome regulatory particle assembly; ISS:UniProtKB. | 3 | O00233 | 223 | PSMD9_HUMAN 26S proteasome non-ATPase regulat... | 194 | 2e-23 | 98.6 | 31 | 55 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0005838; C:proteasome regulatory particle; NAS:UniProtKB. | | | | | | | | | | GO:0043425; F:bHLH transcription factor binding; ISS:BHF-UCL.::GO:0003713; F:transcription coactivator activity; ISS:BHF-UCL. | | | | | | | | | | GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.::GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.::GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0006977; P:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; TAS:Reactome.::GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.::GO:0010467; P:gene expression; TAS:Reactome.::GO:0000216; P:M/G1 transition of mitotic cell cycle; TAS:Reactome.::GO:0016071; P:mRNA metabolic process; TAS:Reactome.::GO:0046676; P:negative regulation of insulin secretion; ISS:BHF-UCL.::GO:0051436; P:negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.::GO:0032024; P:positive regulation of insulin secretion; ISS:BHF-UCL.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:BHF-UCL.::GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.::GO:0070682; P:proteasome regulatory particle assembly; IMP:UniProtKB.::GO:0000209; P:protein polyubiquitination; TAS:Reactome.::GO:0042981; P:regulation of apoptotic process; TAS:Reactome.::GO:0006521; P:regulation of cellular amino acid metabolic process; TAS:Reactome.::GO:0000084; P:S phase of mitotic cell cycle; TAS:Reactome.::GO:0044281; P:small molecule metabolic process; TAS:Reactome.::GO:0016032; P:viral reproduction; TAS:Reactome. | 4 | Q9CR00 | 222 | PSMD9_MOUSE 26S proteasome non-ATPase regulat... | 193 | 1e-21 | 93.6 | 31 | 54 | GO:0005634; C:nucleus; ISS:BHF-UCL. | | | | | | | | | | GO:0043425; F:bHLH transcription factor binding; ISS:BHF-UCL.::GO:0003713; F:transcription coactivator activity; ISS:BHF-UCL. | | | | | | | | | | GO:0046676; P:negative regulation of insulin secretion; ISS:BHF-UCL.::GO:0032024; P:positive regulation of insulin secretion; ISS:BHF-UCL.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:BHF-UCL.::GO:0070682; P:proteasome regulatory particle assembly; ISS:UniProtKB. | 5 | O94393 | 213 | PSMD9_SCHPO Probable 26S proteasome regulator... | 217 | 5e-21 | 91.7 | 35 | 46 | GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase. | | | | | | | | | | | | | | | | | | | | GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; IC:PomBase.::GO:0070682; P:proteasome regulatory particle assembly; ISS:PomBase. | 6 | Q9WTV5 | 222 | PSMD9_RAT 26S proteasome non-ATPase regulator... | 193 | 6e-21 | 92 | 31 | 53 | GO:0005634; C:nucleus; IDA:BHF-UCL. | | | | | | | | | | GO:0043425; F:bHLH transcription factor binding; IDA:BHF-UCL.::GO:0008022; F:protein C-terminus binding; IPI:RGD.::GO:0003713; F:transcription coactivator activity; IDA:BHF-UCL. | | | | | | | | | | GO:0006915; P:apoptotic process; IMP:BHF-UCL.::GO:0046676; P:negative regulation of insulin secretion; IMP:BHF-UCL.::GO:0032024; P:positive regulation of insulin secretion; IDA:BHF-UCL.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:RGD.::GO:0070682; P:proteasome regulatory particle assembly; ISS:UniProtKB. | 7 | Q10920 | 197 | PSMD9_CAEEL Probable 26S proteasome non-ATPas... | 191 | 5e-17 | 80.1 | 29 | 50 | | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | | 8 | Q552Y8 | 262 | PSMD9_DICDI Probable 26S proteasome non-ATPas... | 105 | 0.0000000003 | 61.6 | 35 | 52 | GO:0005838; C:proteasome regulatory particle; ISS:dictyBase. | | | | | | | | | | | | | | | | | | | | GO:0006511; P:ubiquitin-dependent protein catabolic process; ISS:dictyBase. | 9 | P73714 | 366 | Y1821_SYNY3 Putative zinc metalloprotease slr... | 84 | 0.004 | 41.6 | 26 | 51 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 10 | O67776 | 429 | Y1964_AQUAE Putative zinc metalloprotease aq_... | 128 | 0.015 | 39.7 | 29 | 43 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 11 | Q9CDT3 | 428 | Y2128_LACLA Putative zinc metalloprotease LL2... | 68 | 0.038 | 38.5 | 31 | 56 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 12 | Q8YQ64 | 364 | Y3971_NOSS1 Putative zinc metalloprotease all... | 75 | 0.36 | 35.4 | 28 | 55 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 13 | Q2SL36 | 469 | DEGPL_HAHCH Probable periplasmic serine endop... | 76 | 0.92 | 34.3 | 30 | 57 | GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0006950; P:response to stress; IEA:UniProtKB-KW. | 14 | Q9JIY5 | 458 | HTRA2_MOUSE Serine protease HTRA2, mitochondr... | 68 | 1.2 | 33.9 | 29 | 56 | GO:0035631; C:CD40 receptor complex; IDA:BHF-UCL.::GO:0009898; C:internal side of plasma membrane; IDA:BHF-UCL.::GO:0005758; C:mitochondrial intermembrane space; IEA:UniProtKB-SubCell.::GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct.::GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0007628; P:adult walking behavior; IMP:MGI.::GO:0030900; P:forebrain development; IMP:MGI.::GO:0008629; P:induction of apoptosis by intracellular signals; IMP:MGI.::GO:0007005; P:mitochondrion organization; IMP:MGI.::GO:0048666; P:neuron development; IMP:MGI.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0040014; P:regulation of multicellular organism growth; IMP:MGI. | 15 | Q6GMI0 | 479 | HTR1A_DANRE Serine protease HTRA1A OS=Danio r... | 71 | 1.2 | 33.9 | 38 | 54 | GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005520; F:insulin-like growth factor binding; IEA:InterPro.::GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0001558; P:regulation of cell growth; IEA:InterPro. | 16 | P72780 | 394 | HHOA_SYNY3 Putative serine protease HhoA OS=S... | 66 | 1.3 | 33.5 | 32 | 59 | GO:0030288; C:outer membrane-bounded periplasmic space; IDA:UniProtKB. | | | | | | | | | | GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 17 | O05942 | 513 | DEGPL_RICPR Probable periplasmic serine endop... | 72 | 2.6 | 32.7 | 31 | 57 | GO:0030288; C:outer membrane-bounded periplasmic space; ISS:UniProtKB. | | | | | | | | | | GO:0004252; F:serine-type endopeptidase activity; ISS:UniProtKB. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0006950; P:response to stress; IEA:UniProtKB-KW. | 18 | O43464 | 458 | HTRA2_HUMAN Serine protease HTRA2, mitochondr... | 68 | 3.4 | 32.3 | 28 | 54 | GO:0035631; C:CD40 receptor complex; ISS:BHF-UCL.::GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0005789; C:endoplasmic reticulum membrane; TAS:UniProtKB.::GO:0009898; C:internal side of plasma membrane; ISS:BHF-UCL.::GO:0005758; C:mitochondrial intermembrane space; IDA:MGI.::GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; TAS:UniProtKB. | | | | | | | | | | GO:0004252; F:serine-type endopeptidase activity; TAS:UniProtKB.::GO:0051082; F:unfolded protein binding; NAS:UniProtKB. | | | | | | | | | | GO:0007050; P:cell cycle arrest; TAS:UniProtKB.::GO:0071363; P:cellular response to growth factor stimulus; IMP:UniProtKB.::GO:0006923; P:cleavage of cytoskeletal proteins involved in apoptosis; TAS:UniProtKB.::GO:0097194; P:execution phase of apoptosis; TAS:UniProtKB.::GO:0043280; P:positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; IDA:UniProtKB.::GO:2001244; P:positive regulation of intrinsic apoptotic signaling pathway; IMP:UniProtKB.::GO:0006950; P:response to stress; TAS:UniProtKB. | 19 | B1MX30 | 239 | RSMG_LEUCK Ribosomal RNA small subunit methyl... | 171 | 3.8 | 32 | 22 | 41 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008649; F:rRNA methyltransferase activity; IEA:InterPro. | | | | | | | | | | | 20 | Q8PVT4 | 189 | HPRT_METMA Hypoxanthine/guanine phosphoribosy... | 48 | 4 | 31.6 | 38 | 60 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0052657; F:guanine phosphoribosyltransferase activity; IEA:EC.::GO:0004422; F:hypoxanthine phosphoribosyltransferase activity; IEA:EC. | | | | | | | | | | GO:0006166; P:purine ribonucleoside salvage; IEA:UniProtKB-KW. | 21 | Q8TSS8 | 189 | HPRT_METAC Hypoxanthine/guanine phosphoribosy... | 48 | 5.1 | 31.2 | 31 | 63 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0052657; F:guanine phosphoribosyltransferase activity; IEA:EC.::GO:0004422; F:hypoxanthine phosphoribosyltransferase activity; IEA:EC. | | | | | | | | | | GO:0006166; P:purine ribonucleoside salvage; IEA:UniProtKB-KW. | 22 | A9JRB3 | 476 | HTR1B_DANRE Serine protease HTRA1B OS=Danio r... | 74 | 9.3 | 31.2 | 35 | 51 | GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005520; F:insulin-like growth factor binding; IEA:InterPro.::GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0001558; P:regulation of cell growth; IEA:InterPro. |
