rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | P11710 | 512 | FUS1_YEAST Nuclear fusion protein FUS1 OS=Sac... | 26 | 1.8 | 34.3 | 42 | 73 | GO:0005938; C:cell cortex; IMP:GOC.::GO:0005887; C:integral to plasma membrane; IDA:SGD.::GO:0043332; C:mating projection tip; IDA:SGD. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0032065; P:cortical protein anchoring; IMP:SGD.::GO:0000755; P:cytogamy; IMP:SGD.::GO:0031385; P:regulation of termination of mating projection growth; IMP:SGD. | 2 | A1X283 | 911 | SPD2B_HUMAN SH3 and PX domain-containing prot... | 63 | 8.8 | 32.3 | 27 | 44 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0042995; C:cell projection; IEA:UniProtKB-KW.::GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0002102; C:podosome; ISS:UniProtKB. | | | | | | | | | | GO:0080025; F:phosphatidylinositol-3,5-bisphosphate binding; ISS:UniProtKB.::GO:0032266; F:phosphatidylinositol-3-phosphate binding; ISS:UniProtKB.::GO:0010314; F:phosphatidylinositol-5-phosphate binding; ISS:UniProtKB.::GO:0042169; F:SH2 domain binding; ISS:UniProtKB. | | | | | | | | | | GO:0060612; P:adipose tissue development; ISS:UniProtKB.::GO:0060348; P:bone development; IMP:UniProtKB.::GO:0007154; P:cell communication; IEA:InterPro.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0022617; P:extracellular matrix disassembly; IMP:UniProtKB.::GO:0001654; P:eye development; IMP:UniProtKB.::GO:0007507; P:heart development; IMP:UniProtKB.::GO:0071800; P:podosome assembly; ISS:UniProtKB.::GO:0072657; P:protein localization in membrane; IDA:UniProtKB.::GO:0006801; P:superoxide metabolic process; IDA:UniProtKB. | 3 | P39969 | 1040 | BOI2_YEAST Protein BOI2 OS=Saccharomyces cere... | 77 | 0.093 | 38.5 | 32 | 49 | GO:0005935; C:cellular bud neck; IDA:SGD.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0007118; P:budding cell apical bud growth; IGI:SGD.::GO:0030010; P:establishment of cell polarity; TAS:SGD.::GO:0007266; P:Rho protein signal transduction; TAS:SGD. | 4 | A2AAY5 | 908 | SPD2B_MOUSE SH3 and PX domain-containing prot... | 97 | 2.5 | 33.9 | 30 | 43 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0042995; C:cell projection; IEA:UniProtKB-KW.::GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0002102; C:podosome; IDA:UniProtKB. | | | | | | | | | | GO:0080025; F:phosphatidylinositol-3,5-bisphosphate binding; IDA:UniProtKB.::GO:0032266; F:phosphatidylinositol-3-phosphate binding; IMP:UniProtKB.::GO:0070273; F:phosphatidylinositol-4-phosphate binding; IDA:UniProtKB.::GO:0010314; F:phosphatidylinositol-5-phosphate binding; IDA:UniProtKB.::GO:0042169; F:SH2 domain binding; IDA:UniProtKB. | | | | | | | | | | GO:0060612; P:adipose tissue development; IMP:UniProtKB.::GO:0060348; P:bone development; IMP:UniProtKB.::GO:0007154; P:cell communication; IEA:InterPro.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0001654; P:eye development; IMP:UniProtKB.::GO:0007507; P:heart development; IMP:UniProtKB.::GO:0071800; P:podosome assembly; IMP:UniProtKB.::GO:0045600; P:positive regulation of fat cell differentiation; IMP:UniProtKB.::GO:0072657; P:protein localization in membrane; ISS:UniProtKB.::GO:0006801; P:superoxide metabolic process; ISS:UniProtKB. | 5 | Q7ZY29 | 688 | ESRP1_XENLA Epithelial splicing regulatory pr... | 98 | 0.24 | 37.4 | 31 | 46 | GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0003729; F:mRNA binding; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0043484; P:regulation of RNA splicing; ISS:UniProtKB.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW. | 6 | P38041 | 980 | BOB1_YEAST Protein BOB1 OS=Saccharomyces cere... | 69 | 0.25 | 37.4 | 29 | 52 | GO:0005935; C:cellular bud neck; IDA:SGD.::GO:0043332; C:mating projection tip; IDA:SGD. | | | | | | | | | | GO:0005543; F:phospholipid binding; IDA:SGD.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0007118; P:budding cell apical bud growth; IGI:SGD.::GO:0030010; P:establishment of cell polarity; TAS:SGD.::GO:0007266; P:Rho protein signal transduction; TAS:SGD. | 7 | O88488 | 2302 | PTPRQ_RAT Phosphotidylinositol phosphatase PT... | 145 | 0.59 | 36.2 | 24 | 44 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0045598; P:regulation of fat cell differentiation; ISS:UniProtKB. | 8 | Q1LYG0 | 1119 | SPD2A_DANRE SH3 and PX domain-containing prot... | 83 | 8.1 | 32.3 | 33 | 49 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0042995; C:cell projection; IEA:UniProtKB-KW.::GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0002102; C:podosome; ISS:UniProtKB. | | | | | | | | | | GO:0035091; F:phosphatidylinositol binding; IEA:InterPro. | | | | | | | | | | GO:0007154; P:cell communication; IEA:InterPro.::GO:0006801; P:superoxide metabolic process; ISS:UniProtKB. | 9 | Q96DR7 | 871 | ARHGQ_HUMAN Rho guanine nucleotide exchange f... | 63 | 0.76 | 35.8 | 29 | 51 | GO:0005622; C:intracellular; IEA:InterPro.::GO:0001726; C:ruffle; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro. | 10 | O77774 | 392 | NCF1_BOVIN Neutrophil cytosol factor 1 OS=Bos... | 65 | 0.76 | 35.4 | 32 | 46 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0035091; F:phosphatidylinositol binding; ISS:UniProtKB. | | | | | | | | | | GO:0007154; P:cell communication; IEA:InterPro.::GO:0006612; P:protein targeting to membrane; ISS:UniProtKB. | 11 | Q6DEZ7 | 687 | ESRP1_XENTR Epithelial splicing regulatory pr... | 98 | 1.1 | 35 | 31 | 45 | GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0003729; F:mRNA binding; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0043484; P:regulation of RNA splicing; ISS:UniProtKB.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW. | 12 | Q8C120 | 878 | SH3R3_MOUSE SH3 domain-containing RING finger... | 54 | 3.2 | 33.9 | 33 | 50 | | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 13 | P47939 | 175 | RES18_MOUSE Regulated endocrine-specific prot... | 41 | 1.7 | 33.5 | 39 | 54 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 14 | Q8DNE6 | 162 | COAD_STRR6 Phosphopantetheine adenylyltransfe... | 62 | 1.7 | 33.5 | 39 | 50 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004595; F:pantetheine-phosphate adenylyltransferase activity; IEA:EC. | | | | | | | | | | GO:0015937; P:coenzyme A biosynthetic process; IEA:UniProtKB-KW. | 15 | Q04IK0 | 162 | COAD_STRP2 Phosphopantetheine adenylyltransfe... | 62 | 1.7 | 33.5 | 39 | 50 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004595; F:pantetheine-phosphate adenylyltransferase activity; IEA:EC. | | | | | | | | | | GO:0015937; P:coenzyme A biosynthetic process; IEA:UniProtKB-KW. | 16 | Q8IVI9 | 506 | NOSTN_HUMAN Nostrin OS=Homo sapiens (Human). ... | 65 | 1.8 | 34.3 | 31 | 42 | GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0030666; C:endocytic vesicle membrane; TAS:Reactome.::GO:0005886; C:plasma membrane; TAS:Reactome. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0046209; P:nitric oxide metabolic process; TAS:Reactome.::GO:0050999; P:regulation of nitric-oxide synthase activity; TAS:Reactome.::GO:0044281; P:small molecule metabolic process; TAS:Reactome. | 17 | C1CGQ1 | 162 | COAD_STRZJ Phosphopantetheine adenylyltransfe... | 62 | 1.9 | 33.5 | 39 | 50 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004595; F:pantetheine-phosphate adenylyltransferase activity; IEA:EC. | | | | | | | | | | GO:0015937; P:coenzyme A biosynthetic process; IEA:UniProtKB-KW. | 18 | Q8TEJ3 | 882 | SH3R3_HUMAN SH3 domain-containing RING finger... | 43 | 2.2 | 34.3 | 35 | 51 | | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 19 | P0CF33 | 103 | SD25N_YEAST Truncated guanine nucleotide exch... | 46 | 2.8 | 31.6 | 35 | 54 | | | | | | | | | | | | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW. | 20 | A5D7F8 | 840 | SH3R1_BOVIN E3 ubiquitin-protein ligase SH3RF... | 40 | 2.8 | 33.9 | 35 | 50 | GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 21 | P0C5E4 | 2300 | PTPRQ_MOUSE Phosphotidylinositol phosphatase ... | 145 | 3.4 | 33.9 | 23 | 43 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0042472; P:inner ear morphogenesis; IMP:MGI.::GO:0045598; P:regulation of fat cell differentiation; ISS:UniProtKB. | 22 | Q09014 | 390 | NCF1_MOUSE Neutrophil cytosol factor 1 OS=Mus... | 42 | 3.5 | 33.5 | 36 | 52 | GO:0005829; C:cytosol; TAS:MGI. | | | | | | | | | | GO:0035091; F:phosphatidylinositol binding; ISS:UniProtKB.::GO:0005515; F:protein binding; IPI:MGI.::GO:0016175; F:superoxide-generating NADPH oxidase activity; IDA:MGI. | | | | | | | | | | GO:0007154; P:cell communication; IEA:InterPro.::GO:0008283; P:cell proliferation; IMP:MGI.::GO:0006968; P:cellular defense response; IMP:MGI.::GO:0050665; P:hydrogen peroxide biosynthetic process; IMP:MGI.::GO:0006954; P:inflammatory response; IMP:MGI.::GO:0006691; P:leukotriene metabolic process; IMP:MGI.::GO:0045986; P:negative regulation of smooth muscle contraction; IMP:MGI.::GO:0070947; P:neutrophil mediated killing of fungus; IMP:MGI.::GO:0070946; P:neutrophil mediated killing of gram-positive bacterium; IMP:MGI.::GO:0006612; P:protein targeting to membrane; ISS:UniProtKB.::GO:0002679; P:respiratory burst involved in defense response; IMP:MGI.::GO:0001878; P:response to yeast; IMP:MGI.::GO:0042554; P:superoxide anion generation; IMP:MGI. | 23 | Q28E95 | 861 | SH3R1_XENTR E3 ubiquitin-protein ligase SH3RF... | 43 | 4 | 33.5 | 40 | 51 | GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 24 | P14598 | 390 | NCF1_HUMAN Neutrophil cytosol factor 1 OS=Hom... | 42 | 4.5 | 33.1 | 33 | 55 | GO:0005829; C:cytosol; TAS:ProtInc.::GO:0043020; C:NADPH oxidase complex; TAS:BHF-UCL.::GO:0032010; C:phagolysosome; TAS:Reactome.::GO:0005625; C:soluble fraction; TAS:ProtInc. | | | | | | | | | | GO:0009055; F:electron carrier activity; TAS:UniProtKB.::GO:0005525; F:GTP binding; TAS:ProtInc.::GO:0003924; F:GTPase activity; TAS:ProtInc.::GO:0035091; F:phosphatidylinositol binding; IDA:UniProtKB.::GO:0017124; F:SH3 domain binding; IPI:BHF-UCL. | | | | | | | | | | GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.::GO:0007154; P:cell communication; IEA:InterPro.::GO:0006968; P:cellular defense response; TAS:ProtInc.::GO:0045087; P:innate immune response; TAS:BHF-UCL.::GO:0006612; P:protein targeting to membrane; IDA:UniProtKB.::GO:0042554; P:superoxide anion generation; TAS:BHF-UCL. | 25 | P42657 | 270 | RAD25_SCHPO DNA damage checkpoint protein rad... | 63 | 4.8 | 32.7 | 32 | 48 | GO:0032153; C:cell division site; IDA:PomBase.::GO:0051286; C:cell tip; IDA:PomBase.::GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase. | | | | | | | | | | GO:0019904; F:protein domain specific binding; IEA:InterPro.::GO:0046982; F:protein heterodimerization activity; IPI:PomBase.::GO:0004860; F:protein kinase inhibitor activity; IGI:PomBase. | | | | | | | | | | GO:0034613; P:cellular protein localization; IGI:PomBase.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006270; P:DNA-dependent DNA replication initiation; ISS:PomBase.::GO:0007095; P:mitotic cell cycle G2/M transition DNA damage checkpoint; IMP:PomBase. | 26 | A6NI72 | 391 | NCF1B_HUMAN Putative neutrophil cytosol facto... | 42 | 4.8 | 32.7 | 33 | 55 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0035091; F:phosphatidylinositol binding; IEA:InterPro. | | | | | | | | | | GO:0007154; P:cell communication; IEA:InterPro. | 27 | A8MVU1 | 366 | NCF1C_HUMAN Putative neutrophil cytosol facto... | 42 | 4.8 | 32.7 | 33 | 52 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.::GO:0016175; F:superoxide-generating NADPH oxidase activity; IEA:InterPro. | | | | | | | | | | GO:0007154; P:cell communication; IEA:InterPro. | 28 | Q6NRD3 | 826 | SH3R1_XENLA E3 ubiquitin-protein ligase SH3RF... | 43 | 5.7 | 32.7 | 40 | 51 | GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 29 | Q4FZU8 | 1217 | FA65A_RAT Protein FAM65A OS=Rattus norvegicus... | 115 | 7.1 | 32.7 | 31 | 45 | GO:0005737; C:cytoplasm; ISS:UniProtKB. | | | | | | | | | | GO:0005488; F:binding; IEA:InterPro. | | | | | | | | | | | 30 | P50545 | 524 | HCK_RAT Tyrosine-protein kinase HCK OS=Rattus... | 119 | 7.2 | 32.3 | 24 | 44 | GO:0005901; C:caveola; IEA:UniProtKB-SubCell.::GO:0042995; C:cell projection; IEA:UniProtKB-KW.::GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0031234; C:extrinsic to internal side of plasma membrane; ISS:UniProtKB.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0005764; C:lysosome; ISS:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0030133; C:transport vesicle; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | GO:0006887; P:exocytosis; IEA:UniProtKB-KW.::GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW.::GO:0018108; P:peptidyl-tyrosine phosphorylation; ISS:UniProtKB.::GO:0006909; P:phagocytosis; IEA:UniProtKB-KW.::GO:2000251; P:positive regulation of actin cytoskeleton reorganization; ISS:UniProtKB.::GO:0008284; P:positive regulation of cell proliferation; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0008360; P:regulation of cell shape; ISS:UniProtKB.::GO:0050764; P:regulation of phagocytosis; ISS:UniProtKB.::GO:0071801; P:regulation of podosome assembly; ISS:UniProtKB. | 31 | Q97NQ2 | 162 | COAD_STRPN Phosphopantetheine adenylyltransfe... | 77 | 7.9 | 31.6 | 31 | 45 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004595; F:pantetheine-phosphate adenylyltransferase activity; IEA:EC. | | | | | | | | | | GO:0015937; P:coenzyme A biosynthetic process; IEA:UniProtKB-KW. |