| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | C8VCL5 | 503 | Y0929_EMENI Uncharacterized rhomboid protein ... | 375 | 1e-90 | 297 | 43 | 60 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 2 | Q6GMF8 | 857 | RHDF1_DANRE Inactive rhomboid protein 1 OS=Da... | 264 | 2e-20 | 100 | 28 | 46 | GO:0005789; C:endoplasmic reticulum membrane; ISS:UniProtKB.::GO:0000139; C:Golgi membrane; ISS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0019838; F:growth factor binding; IEA:UniProtKB-KW.::GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0016477; P:cell migration; ISS:UniProtKB.::GO:0008283; P:cell proliferation; ISS:UniProtKB.::GO:0050709; P:negative regulation of protein secretion; ISS:UniProtKB.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:InterPro.::GO:0042058; P:regulation of epidermal growth factor receptor signaling pathway; ISS:UniProtKB.::GO:0061136; P:regulation of proteasomal protein catabolic process; ISS:UniProtKB. | 3 | Q6PIX5 | 856 | RHDF1_MOUSE Inactive rhomboid protein 1 OS=Mu... | 264 | 7e-19 | 94.7 | 27 | 45 | GO:0005789; C:endoplasmic reticulum membrane; ISS:UniProtKB.::GO:0000139; C:Golgi membrane; ISS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0016477; P:cell migration; ISS:UniProtKB.::GO:0008283; P:cell proliferation; ISS:UniProtKB.::GO:0050709; P:negative regulation of protein secretion; ISS:UniProtKB.::GO:0006508; P:proteolysis; IEA:InterPro.::GO:0042058; P:regulation of epidermal growth factor receptor signaling pathway; ISS:UniProtKB.::GO:0061136; P:regulation of proteasomal protein catabolic process; ISS:UniProtKB. | 4 | A7YWH9 | 856 | RHDF1_BOVIN Inactive rhomboid protein 1 OS=Bo... | 264 | 1e-18 | 94.4 | 27 | 45 | GO:0005789; C:endoplasmic reticulum membrane; ISS:UniProtKB.::GO:0000139; C:Golgi membrane; ISS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0019838; F:growth factor binding; IEA:UniProtKB-KW.::GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0016477; P:cell migration; ISS:UniProtKB.::GO:0008283; P:cell proliferation; ISS:UniProtKB.::GO:0050709; P:negative regulation of protein secretion; ISS:UniProtKB.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:InterPro.::GO:0042058; P:regulation of epidermal growth factor receptor signaling pathway; ISS:UniProtKB.::GO:0061136; P:regulation of proteasomal protein catabolic process; ISS:UniProtKB. | 5 | Q499S9 | 856 | RHDF1_RAT Inactive rhomboid protein 1 OS=Ratt... | 176 | 1e-18 | 94.4 | 31 | 52 | GO:0005789; C:endoplasmic reticulum membrane; ISS:UniProtKB.::GO:0000139; C:Golgi membrane; ISS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0019838; F:growth factor binding; IEA:UniProtKB-KW.::GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0016477; P:cell migration; ISS:UniProtKB.::GO:0008283; P:cell proliferation; ISS:UniProtKB.::GO:0050709; P:negative regulation of protein secretion; ISS:UniProtKB.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:InterPro.::GO:0042058; P:regulation of epidermal growth factor receptor signaling pathway; ISS:UniProtKB.::GO:0061136; P:regulation of proteasomal protein catabolic process; ISS:UniProtKB. | 6 | A9L8T6 | 855 | RHDF1_PAPAN Inactive rhomboid protein 1 OS=Pa... | 264 | 1e-18 | 94 | 27 | 45 | GO:0005789; C:endoplasmic reticulum membrane; ISS:UniProtKB.::GO:0000139; C:Golgi membrane; ISS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0019838; F:growth factor binding; IEA:UniProtKB-KW.::GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0016477; P:cell migration; ISS:UniProtKB.::GO:0008283; P:cell proliferation; ISS:UniProtKB.::GO:0050709; P:negative regulation of protein secretion; ISS:UniProtKB.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:InterPro.::GO:0042058; P:regulation of epidermal growth factor receptor signaling pathway; ISS:UniProtKB.::GO:0061136; P:regulation of proteasomal protein catabolic process; ISS:UniProtKB. | 7 | B1MT31 | 855 | RHDF1_CALMO Inactive rhomboid protein 1 OS=Ca... | 176 | 2e-18 | 93.6 | 31 | 52 | GO:0005789; C:endoplasmic reticulum membrane; ISS:UniProtKB.::GO:0000139; C:Golgi membrane; ISS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0019838; F:growth factor binding; IEA:UniProtKB-KW.::GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0016477; P:cell migration; ISS:UniProtKB.::GO:0008283; P:cell proliferation; ISS:UniProtKB.::GO:0050709; P:negative regulation of protein secretion; ISS:UniProtKB.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:InterPro.::GO:0042058; P:regulation of epidermal growth factor receptor signaling pathway; ISS:UniProtKB.::GO:0061136; P:regulation of proteasomal protein catabolic process; ISS:UniProtKB. | 8 | Q96CC6 | 855 | RHDF1_HUMAN Inactive rhomboid protein 1 OS=Ho... | 176 | 2e-18 | 93.6 | 31 | 52 | GO:0005789; C:endoplasmic reticulum membrane; IDA:UniProtKB.::GO:0000139; C:Golgi membrane; IDA:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0019838; F:growth factor binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016477; P:cell migration; IMP:UniProtKB.::GO:0008283; P:cell proliferation; IMP:UniProtKB.::GO:0050709; P:negative regulation of protein secretion; IDA:UniProtKB.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:InterPro.::GO:0042058; P:regulation of epidermal growth factor receptor signaling pathway; IMP:UniProtKB.::GO:0061136; P:regulation of proteasomal protein catabolic process; IDA:UniProtKB. | 9 | B0VX73 | 855 | RHDF1_CALJA Inactive rhomboid protein 1 OS=Ca... | 176 | 2e-18 | 93.6 | 31 | 52 | GO:0005789; C:endoplasmic reticulum membrane; ISS:UniProtKB.::GO:0000139; C:Golgi membrane; ISS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0019838; F:growth factor binding; IEA:UniProtKB-KW.::GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0016477; P:cell migration; ISS:UniProtKB.::GO:0008283; P:cell proliferation; ISS:UniProtKB.::GO:0050709; P:negative regulation of protein secretion; ISS:UniProtKB.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:InterPro.::GO:0042058; P:regulation of epidermal growth factor receptor signaling pathway; ISS:UniProtKB.::GO:0061136; P:regulation of proteasomal protein catabolic process; ISS:UniProtKB. | 10 | Q80WQ6 | 827 | RHDF2_MOUSE Inactive rhomboid protein 2 OS=Mu... | 175 | 3e-16 | 86.3 | 32 | 53 | GO:0005789; C:endoplasmic reticulum membrane; IDA:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | | | | | | | | | | | GO:0050709; P:negative regulation of protein secretion; IDA:UniProtKB.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:InterPro. | 11 | Q00M95 | 827 | RHDF2_CANFA Inactive rhomboid protein 2 OS=Ca... | 177 | 5e-16 | 85.9 | 32 | 55 | GO:0005789; C:endoplasmic reticulum membrane; ISS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0019838; F:growth factor binding; IEA:UniProtKB-KW.::GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0050709; P:negative regulation of protein secretion; ISS:UniProtKB.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:InterPro. | 12 | A0JPA1 | 826 | RHDF2_XENTR Inactive rhomboid protein 2 OS=Xe... | 87 | 4.3 | 34.3 | 26 | 48 | GO:0005789; C:endoplasmic reticulum membrane; ISS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0019838; F:growth factor binding; IEA:UniProtKB-KW.::GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0050709; P:negative regulation of protein secretion; ISS:UniProtKB.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:InterPro. | 13 | Q6PJF5 | 856 | RHDF2_HUMAN Inactive rhomboid protein 2 OS=Ho... | 177 | 6e-16 | 85.5 | 32 | 55 | GO:0005789; C:endoplasmic reticulum membrane; ISS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0019838; F:growth factor binding; IEA:UniProtKB-KW.::GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0050709; P:negative regulation of protein secretion; ISS:UniProtKB.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:InterPro. | 14 | Q76NQ1 | 1429 | RHDF1_DROME Inactive rhomboid protein 1 OS=Dr... | 182 | 0.00000000000008 | 79 | 30 | 49 | GO:0005789; C:endoplasmic reticulum membrane; IDA:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | | | | | | | | | | | GO:0042059; P:negative regulation of epidermal growth factor receptor signaling pathway; IMP:UniProtKB.::GO:0010841; P:positive regulation of circadian sleep/wake cycle, wakefulness; IMP:UniProtKB.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:InterPro.::GO:0030431; P:sleep; IMP:FlyBase. | 15 | P96617 | 199 | YDCA_BACSU Putative rhomboid protease ydcA OS... | 144 | 0.0000000000008 | 72 | 26 | 51 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 16 | P46116 | 281 | AARA_PROST Rhomboid protease AarA OS=Providen... | 167 | 0.00000000007 | 67 | 33 | 47 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 17 | P54493 | 507 | GLUP_BACSU Rhomboid protease gluP OS=Bacillus... | 145 | 0.00000000008 | 68.6 | 30 | 50 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005488; F:binding; IEA:InterPro.::GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 18 | Q695T8 | 641 | RHBL4_TOXGO Rhomboid-like protease 4 OS=Toxop... | 139 | 0.0000000005 | 66.2 | 30 | 55 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 19 | Q6IUY1 | 263 | RHBL3_TOXGO Rhomboid-like protease 3 OS=Toxop... | 148 | 0.000000001 | 63.2 | 32 | 49 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 20 | Q695U0 | 293 | RHBL1_TOXGO Rhomboid-like protease 1 OS=Toxop... | 155 | 0.0000005 | 55.5 | 31 | 51 | GO:0031410; C:cytoplasmic vesicle; IEA:UniProtKB-KW.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0033163; C:microneme membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 21 | Q695T9 | 283 | RHBL2_TOXGO Rhomboid-like protease 2 OS=Toxop... | 140 | 0.000005 | 52.4 | 25 | 46 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 22 | P58872 | 404 | RHBL3_HUMAN Rhomboid-related protein 3 OS=Hom... | 178 | 0.00001 | 51.6 | 25 | 43 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 23 | P34356 | 435 | ROM2_CAEEL Rhomboid-related protein 2 OS=Caen... | 195 | 0.00002 | 51.2 | 26 | 45 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 24 | Q6GV23 | 841 | RHBL5_TOXGO Rhomboid-like protease 5 OS=Toxop... | 128 | 0.0001 | 48.9 | 25 | 51 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 25 | P20350 | 355 | RHOM_DROME Protein rhomboid OS=Drosophila mel... | 88 | 0.0002 | 48.1 | 31 | 55 | GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; TAS:FlyBase. | | | | | | | | | | GO:0004252; F:serine-type endopeptidase activity; IDA:FlyBase. | | | | | | | | | | GO:0007409; P:axonogenesis; IMP:FlyBase.::GO:0048149; P:behavioral response to ethanol; IMP:FlyBase.::GO:0007420; P:brain development; IMP:FlyBase.::GO:0046845; P:branched duct epithelial cell fate determination, open tracheal system; TAS:FlyBase.::GO:0016337; P:cell-cell adhesion; IMP:FlyBase.::GO:0000910; P:cytokinesis; IMP:FlyBase.::GO:0035225; P:determination of genital disc primordium; IMP:FlyBase.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:FlyBase.::GO:0061331; P:epithelial cell proliferation involved in Malpighian tubule morphogenesis; IMP:FlyBase.::GO:0008586; P:imaginal disc-derived wing vein morphogenesis; IMP:FlyBase.::GO:0007474; P:imaginal disc-derived wing vein specification; IMP:FlyBase.::GO:0007479; P:leg disc proximal/distal pattern formation; TAS:FlyBase.::GO:0035160; P:maintenance of epithelial integrity, open tracheal system; IMP:FlyBase.::GO:0001763; P:morphogenesis of a branching structure; NAS:FlyBase.::GO:0010629; P:negative regulation of gene expression; IMP:FlyBase.::GO:0007438; P:oenocyte development; IMP:FlyBase.::GO:0008355; P:olfactory learning; IMP:FlyBase.::GO:0030707; P:ovarian follicle cell development; TAS:FlyBase.::GO:0038005; P:peptide bond cleavage involved in epidermal growth factor receptor ligand maturation; IGI:FlyBase.::GO:0007422; P:peripheral nervous system development; TAS:FlyBase.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0007432; P:salivary gland boundary specification; NAS:FlyBase.::GO:0048865; P:stem cell fate commitment; IMP:FlyBase.::GO:0035202; P:tracheal pit formation in open tracheal system; TAS:FlyBase.::GO:0035311; P:wing cell fate specification; IMP:FlyBase. | 26 | P58873 | 404 | RHBL3_MOUSE Rhomboid-related protein 3 OS=Mus... | 178 | 0.0002 | 47.8 | 24 | 42 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 27 | P44783 | 192 | GLPG_HAEIN Rhomboid protease glpG OS=Haemophi... | 153 | 0.0009 | 44.3 | 28 | 47 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 28 | O75783 | 438 | RHBL1_HUMAN Rhomboid-related protein 1 OS=Hom... | 149 | 0.001 | 45.4 | 20 | 44 | GO:0005887; C:integral to plasma membrane; TAS:ProtInc.::GO:0005624; C:membrane fraction; TAS:ProtInc. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0007165; P:signal transduction; TAS:ProtInc. | 29 | Q8VC82 | 373 | RHBL1_MOUSE Rhomboid-related protein 1 OS=Mus... | 149 | 0.006 | 43.1 | 20 | 44 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 30 | A2AGA4 | 302 | RHBL2_MOUSE Rhomboid-related protein 2 OS=Mus... | 171 | 0.008 | 42.4 | 25 | 48 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; ISS:UniProtKB. | | | | | | | | | | GO:0004252; F:serine-type endopeptidase activity; IMP:UniProtKB. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 31 | Q8LB17 | 403 | Y3846_ARATH Uncharacterized protein At3g58460... | 47 | 0.012 | 42.4 | 36 | 64 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro. | | | | | | | | | | |
