rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
31 | Q63713 | 847 | RASA2_RAT Ras GTPase-activating protein 2 OS=... | 162 | 0.0000005 | 59.3 | 28 | 49 | GO:0005737; C:cytoplasm; IBA:RefGenome.::GO:0031235; C:intrinsic to internal side of plasma membrane; IBA:RefGenome. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005099; F:Ras GTPase activator activity; IDA:RGD. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0046580; P:negative regulation of Ras protein signal transduction; IBA:RefGenome. | 32 | Q15283 | 849 | RASA2_HUMAN Ras GTPase-activating protein 2 O... | 156 | 0.0000008 | 58.5 | 28 | 49 | GO:0043231; C:intracellular membrane-bounded organelle; IDA:HPA.::GO:0031235; C:intrinsic to internal side of plasma membrane; IBA:RefGenome.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005099; F:Ras GTPase activator activity; IBA:RefGenome. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0046580; P:negative regulation of Ras protein signal transduction; IBA:RefGenome. | 33 | Q13576 | 1575 | IQGA2_HUMAN Ras GTPase-activating-like protei... | 216 | 0.000002 | 57.8 | 25 | 45 | GO:0015629; C:actin cytoskeleton; TAS:ProtInc. | | | | | | | | | | GO:0003779; F:actin binding; TAS:ProtInc.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0005095; F:GTPase inhibitor activity; TAS:ProtInc.::GO:0005099; F:Ras GTPase activator activity; IEA:InterPro. | | | | | | | | | | GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 34 | Q9QUH6 | 1308 | SYGP1_RAT Ras GTPase-activating protein SynGA... | 190 | 0.000002 | 57.8 | 29 | 47 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005737; C:cytoplasm; IBA:RefGenome.::GO:0031235; C:intrinsic to internal side of plasma membrane; IBA:RefGenome.::GO:0045202; C:synapse; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0046580; P:negative regulation of Ras protein signal transduction; IDA:UniProtKB. | 35 | F6SEU4 | 1340 | SYGP1_MOUSE Ras GTPase-activating protein Syn... | 190 | 0.000002 | 57.4 | 29 | 47 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005737; C:cytoplasm; IBA:RefGenome.::GO:0043198; C:dendritic shaft; IDA:MGI.::GO:0031235; C:intrinsic to internal side of plasma membrane; IBA:RefGenome.::GO:0005624; C:membrane fraction; IDA:MGI.::GO:0045202; C:synapse; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005097; F:Rab GTPase activator activity; IDA:MGI.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016358; P:dendrite development; IMP:MGI.::GO:0043066; P:negative regulation of apoptotic process; IMP:MGI.::GO:0050771; P:negative regulation of axonogenesis; IDA:MGI.::GO:0046580; P:negative regulation of Ras protein signal transduction; ISS:UniProtKB.::GO:0007389; P:pattern specification process; IMP:MGI.::GO:0007265; P:Ras protein signal transduction; IDA:MGI.::GO:0043113; P:receptor clustering; IMP:MGI.::GO:0048169; P:regulation of long-term neuronal synaptic plasticity; IMP:MGI.::GO:0043408; P:regulation of MAPK cascade; IMP:MGI.::GO:0050803; P:regulation of synapse structure and activity; IMP:MGI.::GO:0008542; P:visual learning; IMP:MGI. | 36 | Q96PV0 | 1343 | SYGP1_HUMAN Ras GTPase-activating protein Syn... | 190 | 0.000002 | 57.4 | 29 | 47 | GO:0005737; C:cytoplasm; IBA:RefGenome.::GO:0031235; C:intrinsic to internal side of plasma membrane; IBA:RefGenome. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0046580; P:negative regulation of Ras protein signal transduction; ISS:UniProtKB. | 37 | P33314 | 1104 | BUD2_YEAST Inhibitory regulator protein BUD2/... | 218 | 0.000003 | 56.6 | 24 | 48 | GO:0005737; C:cytoplasm; IBA:RefGenome.::GO:0031235; C:intrinsic to internal side of plasma membrane; IBA:RefGenome. | | | | | | | | | | GO:0005099; F:Ras GTPase activator activity; IBA:RefGenome. | | | | | | | | | | GO:0007120; P:axial cellular bud site selection; TAS:SGD.::GO:0007121; P:bipolar cellular bud site selection; TAS:SGD.::GO:0030447; P:filamentous growth; IMP:SGD.::GO:0046580; P:negative regulation of Ras protein signal transduction; IBA:RefGenome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:SGD. | 38 | Q3UQ44 | 1575 | IQGA2_MOUSE Ras GTPase-activating-like protei... | 216 | 0.000005 | 56.2 | 23 | 44 | GO:0005622; C:intracellular; IEA:InterPro.::GO:0005902; C:microvillus; IDA:MGI. | | | | | | | | | | GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0005099; F:Ras GTPase activator activity; IEA:InterPro. | | | | | | | | | | GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 39 | Q8T498 | 1580 | GAP2_DROME Probable Ras GTPase-activating pro... | 208 | 0.00007 | 52.4 | 27 | 41 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0002121; P:inter-male aggressive behavior; IMP:FlyBase.::GO:0046580; P:negative regulation of Ras protein signal transduction; ISS:UniProtKB.::GO:0007165; P:signal transduction; IEA:InterPro. | 40 | Q9JKF1 | 1657 | IQGA1_MOUSE Ras GTPase-activating-like protei... | 239 | 0.00008 | 52.4 | 21 | 43 | GO:0005622; C:intracellular; IEA:InterPro.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0036057; C:slit diaphragm; ISS:UniProtKB. | | | | | | | | | | GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0005099; F:Ras GTPase activator activity; IEA:InterPro. | | | | | | | | | | GO:0072015; P:glomerular visceral epithelial cell development; ISS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 41 | P46940 | 1657 | IQGA1_HUMAN Ras GTPase-activating-like protei... | 239 | 0.00008 | 52.4 | 22 | 44 | GO:0005884; C:actin filament; TAS:ProtInc.::GO:0005737; C:cytoplasm; IDA:HPA.::GO:0030496; C:midbody; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:HPA.::GO:0036057; C:slit diaphragm; ISS:UniProtKB. | | | | | | | | | | GO:0005516; F:calmodulin binding; TAS:ProtInc.::GO:0005095; F:GTPase inhibitor activity; TAS:ProtInc.::GO:0019903; F:protein phosphatase binding; IPI:UniProtKB.::GO:0005099; F:Ras GTPase activator activity; IEA:InterPro. | | | | | | | | | | GO:0006112; P:energy reserve metabolic process; TAS:Reactome.::GO:0072015; P:glomerular visceral epithelial cell development; ISS:UniProtKB.::GO:0050796; P:regulation of insulin secretion; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0044281; P:small molecule metabolic process; TAS:Reactome. | 42 | Q54K32 | 822 | RGAA_DICDI Ras GTPase-activating-like protein... | 236 | 0.001 | 48.5 | 19 | 43 | GO:0005938; C:cell cortex; TAS:dictyBase.::GO:0032154; C:cleavage furrow; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005516; F:calmodulin binding; ISS:dictyBase.::GO:0048365; F:Rac GTPase binding; IPI:dictyBase.::GO:0005099; F:Ras GTPase activator activity; IDA:dictyBase. | | | | | | | | | | GO:0000910; P:cytokinesis; IMP:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0031149; P:sorocarp stalk cell differentiation; IMP:dictyBase.::GO:0030435; P:sporulation resulting in formation of a cellular spore; IMP:dictyBase. | 43 | Q22720 | 629 | GAP1_CAEEL Ras GTPase-activating protein gap-... | 189 | 0.01 | 45.1 | 22 | 42 | GO:0005737; C:cytoplasm; NAS:UniProtKB.::GO:0031235; C:intrinsic to internal side of plasma membrane; IBA:RefGenome. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005099; F:Ras GTPase activator activity; NAS:UniProtKB. | | | | | | | | | | GO:0046580; P:negative regulation of Ras protein signal transduction; IEP:UniProtKB.::GO:0007165; P:signal transduction; IEA:InterPro. | 44 | Q86VI3 | 1631 | IQGA3_HUMAN Ras GTPase-activating-like protei... | 259 | 0.025 | 43.9 | 20 | 42 | | | | | | | | | | | GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0005099; F:Ras GTPase activator activity; IEA:InterPro. | | | | | | | | | | | 45 | A5D794 | 1413 | GAPD1_BOVIN GTPase-activating protein and VPS... | 110 | 0.63 | 39.3 | 28 | 58 | GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0005768; C:endosome; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0032794; F:GTPase activating protein binding; ISS:UniProtKB.::GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005085; F:guanyl-nucleotide exchange factor activity; ISS:UniProtKB. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0051223; P:regulation of protein transport; ISS:UniProtKB.::GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.::GO:0007165; P:signal transduction; IEA:InterPro. | 46 | Q6PAR5 | 1458 | GAPD1_MOUSE GTPase-activating protein and VPS... | 110 | 0.72 | 39.3 | 28 | 58 | GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0005768; C:endosome; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0032794; F:GTPase activating protein binding; IMP:UniProtKB.::GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005085; F:guanyl-nucleotide exchange factor activity; IMP:UniProtKB. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0051223; P:regulation of protein transport; IMP:UniProtKB.::GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.::GO:0007165; P:signal transduction; IEA:InterPro. | 47 | Q14C86 | 1478 | GAPD1_HUMAN GTPase-activating protein and VPS... | 110 | 1 | 38.5 | 28 | 57 | GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0005768; C:endosome; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0032794; F:GTPase activating protein binding; IMP:UniProtKB.::GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005085; F:guanyl-nucleotide exchange factor activity; IMP:UniProtKB. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0051223; P:regulation of protein transport; IMP:UniProtKB.::GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.::GO:0007165; P:signal transduction; IEA:InterPro. | 48 | O00899 | 860 | GAPA_DICDI Ras GTPase-activating-like protein... | 90 | 2.2 | 37.4 | 27 | 50 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005099; F:Ras GTPase activator activity; IEA:InterPro. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0006972; P:hyperosmotic response; IEP:dictyBase.::GO:0006979; P:response to oxidative stress; IEP:dictyBase.::GO:0019953; P:sexual reproduction; IEP:dictyBase.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 49 | Q608L6 | 424 | GLGC_METCA Glucose-1-phosphate adenylyltransf... | 88 | 2.8 | 37 | 30 | 45 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008878; F:glucose-1-phosphate adenylyltransferase activity; IEA:EC. | | | | | | | | | | GO:0005978; P:glycogen biosynthetic process; IEA:UniProtKB-KW. | 50 | P46838 | 429 | AG45_MYCLE 46 kDa membrane protein OS=Mycobac... | 59 | 5.4 | 35.8 | 32 | 56 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0015105; F:arsenite transmembrane transporter activity; IEA:InterPro.::GO:0015137; F:citrate transmembrane transporter activity; IEA:InterPro. | | | | | | | | | | | 51 | O07187 | 428 | Y2685_MYCTU Uncharacterized transporter Rv268... | 59 | 6.1 | 35.8 | 29 | 56 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0015105; F:arsenite transmembrane transporter activity; IEA:InterPro.::GO:0015137; F:citrate transmembrane transporter activity; IEA:InterPro. | | | | | | | | | | |