| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
241 | B6I7T0 | 384 | BIOF_ECOSE 8-amino-7-oxononanoate synthase OS... | 359 | 4e-33 | 134 | 26 | 49 | | | | | | | | | | | GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro. | | | | | | | | | | GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW. | 242 | A7ZJI5 | 384 | BIOF_ECO24 8-amino-7-oxononanoate synthase OS... | 359 | 4e-33 | 134 | 26 | 49 | | | | | | | | | | | GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro. | | | | | | | | | | GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW. | 243 | P22557 | 587 | HEM0_HUMAN 5-aminolevulinate synthase, erythr... | 375 | 4e-33 | 136 | 29 | 49 | GO:0005743; C:mitochondrial inner membrane; IDA:UniProtKB.::GO:0005759; C:mitochondrial matrix; TAS:Reactome. | | | | | | | | | | GO:0003870; F:5-aminolevulinate synthase activity; IDA:UniProtKB.::GO:0050662; F:coenzyme binding; ISS:UniProtKB.::GO:0016594; F:glycine binding; ISS:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro. | | | | | | | | | | GO:0006879; P:cellular iron ion homeostasis; ISS:UniProtKB.::GO:0030218; P:erythrocyte differentiation; ISS:UniProtKB.::GO:0006783; P:heme biosynthetic process; ISS:UniProtKB.::GO:0042541; P:hemoglobin biosynthetic process; ISS:UniProtKB.::GO:0032364; P:oxygen homeostasis; NAS:UniProtKB.::GO:0001666; P:response to hypoxia; IDA:UniProtKB.::GO:0044281; P:small molecule metabolic process; TAS:Reactome. | 244 | Q6A6M4 | 653 | BIOWF_PROAC Biotin biosynthesis bifunctional ... | 370 | 5e-33 | 137 | 28 | 46 | | | | | | | | | | | GO:0042410; F:6-carboxyhexanoate-CoA ligase activity; IEA:EC.::GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro. | | | | | | | | | | GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW. | 245 | Q47829 | 385 | BIOF_ENTAG 8-amino-7-oxononanoate synthase OS... | 381 | 6e-33 | 133 | 27 | 47 | | | | | | | | | | | GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro. | | | | | | | | | | GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW. | 246 | Q63147 | 587 | HEM0_RAT 5-aminolevulinate synthase, erythroi... | 374 | 6e-33 | 136 | 29 | 49 | GO:0005743; C:mitochondrial inner membrane; ISS:UniProtKB.::GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003870; F:5-aminolevulinate synthase activity; ISS:UniProtKB.::GO:0050662; F:coenzyme binding; IDA:RGD.::GO:0016594; F:glycine binding; IDA:RGD.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro. | | | | | | | | | | GO:0030218; P:erythrocyte differentiation; ISS:UniProtKB.::GO:0007565; P:female pregnancy; IEP:RGD.::GO:0006783; P:heme biosynthetic process; ISS:UniProtKB.::GO:0042541; P:hemoglobin biosynthetic process; ISS:UniProtKB.::GO:0007595; P:lactation; IEP:RGD.::GO:0042493; P:response to drug; IEP:RGD.::GO:0001666; P:response to hypoxia; ISS:UniProtKB.::GO:0010288; P:response to lead ion; IEP:RGD. | 247 | B7NNK6 | 384 | BIOF_ECO7I 8-amino-7-oxononanoate synthase OS... | 359 | 9e-33 | 133 | 26 | 48 | | | | | | | | | | | GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro. | | | | | | | | | | GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW. | 248 | A1ITK1 | 380 | BIOF_NEIMA Putative 8-amino-7-oxononanoate sy... | 362 | 9e-33 | 133 | 26 | 51 | | | | | | | | | | | GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro. | | | | | | | | | | GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW. | 249 | A9M251 | 380 | BIOF_NEIM0 Putative 8-amino-7-oxononanoate sy... | 362 | 9e-33 | 133 | 26 | 51 | | | | | | | | | | | GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro. | | | | | | | | | | GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW. | 250 | B7ULX3 | 384 | BIOF_ECO27 8-amino-7-oxononanoate synthase OS... | 356 | 1e-32 | 132 | 27 | 49 | | | | | | | | | | | GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro. | | | | | | | | | | GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW. | 251 | P09950 | 548 | HEM1_YEAST 5-aminolevulinate synthase, mitoch... | 381 | 1e-32 | 135 | 27 | 47 | GO:0005759; C:mitochondrial matrix; IDA:SGD. | | | | | | | | | | GO:0003870; F:5-aminolevulinate synthase activity; IDA:SGD.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro. | | | | | | | | | | GO:0006783; P:heme biosynthetic process; IMP:SGD. | 252 | B7NA75 | 384 | BIOF_ECOLU 8-amino-7-oxononanoate synthase OS... | 359 | 1e-32 | 132 | 26 | 48 | | | | | | | | | | | GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro. | | | | | | | | | | GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW. | 253 | D4H9Y2 | 668 | BIOWF_PROAS Biotin biosynthesis bifunctional ... | 370 | 1e-32 | 136 | 28 | 46 | | | | | | | | | | | GO:0042410; F:6-carboxyhexanoate-CoA ligase activity; IEA:EC.::GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro. | | | | | | | | | | GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW. | 254 | Q2NUJ6 | 388 | BIOF_SODGM 8-amino-7-oxononanoate synthase OS... | 405 | 1e-32 | 132 | 27 | 46 | | | | | | | | | | | GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro. | | | | | | | | | | GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW. | 255 | P43091 | 627 | HEM1_OPSTA 5-aminolevulinate synthase, nonspe... | 486 | 1e-32 | 135 | 26 | 45 | GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003870; F:5-aminolevulinate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro. | | | | | | | | | | GO:0006783; P:heme biosynthetic process; IEA:UniProtKB-KW. | 256 | A1JS67 | 383 | BIOF_YERE8 8-amino-7-oxononanoate synthase OS... | 370 | 2e-32 | 132 | 27 | 47 | | | | | | | | | | | GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro. | | | | | | | | | | GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW. | 257 | Q146K3 | 394 | BIOF_BURXL 8-amino-7-oxononanoate synthase OS... | 372 | 2e-32 | 132 | 27 | 49 | | | | | | | | | | | GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro. | | | | | | | | | | GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW. | 258 | Q324B6 | 384 | BIOF_SHIBS 8-amino-7-oxononanoate synthase OS... | 359 | 2e-32 | 132 | 26 | 48 | | | | | | | | | | | GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro. | | | | | | | | | | GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW. | 259 | B2TVF4 | 384 | BIOF_SHIB3 8-amino-7-oxononanoate synthase OS... | 359 | 2e-32 | 132 | 26 | 48 | | | | | | | | | | | GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro. | | | | | | | | | | GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW. | 260 | Q6BX71 | 575 | HEM1_DEBHA 5-aminolevulinate synthase, mitoch... | 417 | 2e-32 | 134 | 28 | 45 | GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003870; F:5-aminolevulinate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro. | | | | | | | | | | GO:0006783; P:heme biosynthetic process; IEA:UniProtKB-KW. | 261 | Q9ZCB8 | 414 | HEM1_RICPR 5-aminolevulinate synthase OS=Rick... | 371 | 2e-32 | 132 | 29 | 49 | | | | | | | | | | | GO:0003870; F:5-aminolevulinate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro. | | | | | | | | | | GO:0006783; P:heme biosynthetic process; IEA:UniProtKB-KW. | 262 | Q81ZZ4 | 387 | BIOF_NITEU 8-amino-7-oxononanoate synthase OS... | 369 | 3e-32 | 131 | 25 | 46 | | | | | | | | | | | GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro. | | | | | | | | | | GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW. | 263 | Q8VC19 | 642 | HEM1_MOUSE 5-aminolevulinate synthase, nonspe... | 396 | 3e-32 | 135 | 27 | 46 | GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003870; F:5-aminolevulinate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro. | | | | | | | | | | GO:0006783; P:heme biosynthetic process; IEA:UniProtKB-KW. | 264 | Q0AE73 | 387 | BIOF_NITEC 8-amino-7-oxononanoate synthase OS... | 371 | 3e-32 | 131 | 26 | 47 | | | | | | | | | | | GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro. | | | | | | | | | | GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW. | 265 | B8IBW2 | 379 | BIKB_METNO Putative 8-amino-7-oxononanoate sy... | 367 | 3e-32 | 131 | 27 | 48 | | | | | | | | | | | GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0008890; F:glycine C-acetyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro. | | | | | | | | | | GO:0009058; P:biosynthetic process; IEA:InterPro. | 266 | Q9K0U0 | 380 | BIOF_NEIMB Putative 8-amino-7-oxononanoate sy... | 359 | 3e-32 | 131 | 25 | 51 | | | | | | | | | | | GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro. | | | | | | | | | | GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW. | 267 | A4G5N9 | 388 | BIOF_HERAR 8-amino-7-oxononanoate synthase OS... | 364 | 3e-32 | 131 | 26 | 48 | | | | | | | | | | | GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro. | | | | | | | | | | GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW. | 268 | Q7VL09 | 387 | BIKB_HAEDU Putative 8-amino-7-oxononanoate sy... | 372 | 4e-32 | 131 | 26 | 48 | | | | | | | | | | | GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0008890; F:glycine C-acetyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro. | | | | | | | | | | GO:0009058; P:biosynthetic process; IEA:InterPro. | 269 | A1K6Q1 | 390 | BIOF_AZOSB 8-amino-7-oxononanoate synthase OS... | 364 | 6e-32 | 130 | 28 | 48 | | | | | | | | | | | GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro. | | | | | | | | | | GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW. | 270 | Q92403 | 621 | HEM1_AGABI 5-aminolevulinate synthase, mitoch... | 476 | 8e-32 | 133 | 27 | 45 | GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003870; F:5-aminolevulinate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro. | | | | | | | | | | GO:0006783; P:heme biosynthetic process; IEA:UniProtKB-KW. | 271 | P43090 | 582 | HEM0_OPSTA 5-aminolevulinate synthase, erythr... | 362 | 1e-31 | 132 | 28 | 48 | GO:0005743; C:mitochondrial inner membrane; ISS:UniProtKB.::GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003870; F:5-aminolevulinate synthase activity; ISS:UniProtKB.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro. | | | | | | | | | | GO:0006783; P:heme biosynthetic process; IEA:UniProtKB-KW.::GO:0001666; P:response to hypoxia; ISS:UniProtKB. |
