rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
151 | Q17446 | 377 | PMK1_CAEEL Mitogen-activated protein kinase p... | 354 | 6e-58 | 199 | 36 | 56 | GO:0005829; C:cytosol; IDA:WormBase.::GO:0005634; C:nucleus; IDA:WormBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IDA:UniProtKB.::GO:0008134; F:transcription factor binding; IPI:WormBase. | | | | | | | | | | GO:0050829; P:defense response to Gram-negative bacterium; IMP:WormBase.::GO:0045087; P:innate immune response; IMP:WormBase.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:WormBase.::GO:0012501; P:programmed cell death; IMP:WormBase. | 152 | Q80Y86 | 549 | MK15_MOUSE Mitogen-activated protein kinase 1... | 305 | 5e-57 | 200 | 38 | 54 | GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0046777; P:protein autophosphorylation; ISS:UniProtKB. | 153 | Q8QGV6 | 447 | NLK2_XENLA Serine/threonine-protein kinase NL... | 356 | 2e-56 | 197 | 34 | 53 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0004707; F:MAP kinase activity; IEA:EC.::GO:0008134; F:transcription factor binding; IPI:UniProtKB.::GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB. | | | | | | | | | | GO:0009952; P:anterior/posterior pattern specification; IMP:UniProtKB.::GO:0001707; P:mesoderm formation; IMP:UniProtKB.::GO:0007399; P:nervous system development; IGI:UniProtKB.::GO:0018107; P:peptidyl-threonine phosphorylation; IDA:UniProtKB.::GO:0031398; P:positive regulation of protein ubiquitination; IPI:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0033136; P:serine phosphorylation of STAT3 protein; IMP:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0007179; P:transforming growth factor beta receptor signaling pathway; IMP:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. | 154 | B1H3E1 | 454 | NLK2_XENTR Serine/threonine-protein kinase NL... | 353 | 2e-56 | 197 | 34 | 53 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0004707; F:MAP kinase activity; IEA:EC.::GO:0008134; F:transcription factor binding; ISS:UniProtKB.::GO:0031625; F:ubiquitin protein ligase binding; ISS:UniProtKB. | | | | | | | | | | GO:0009952; P:anterior/posterior pattern specification; ISS:UniProtKB.::GO:0001707; P:mesoderm formation; ISS:UniProtKB.::GO:0007399; P:nervous system development; ISS:UniProtKB.::GO:0018107; P:peptidyl-threonine phosphorylation; ISS:UniProtKB.::GO:0031398; P:positive regulation of protein ubiquitination; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0033136; P:serine phosphorylation of STAT3 protein; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0007179; P:transforming growth factor beta receptor signaling pathway; ISS:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. | 155 | Q966Y3 | 361 | JNK_SUBDO Stress-activated protein kinase JNK... | 363 | 1e-55 | 192 | 34 | 52 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC. | | | | | | | | | | GO:0007254; P:JNK cascade; ISS:UniProtKB. | 156 | Q9UBE8 | 527 | NLK_HUMAN Serine/threonine-protein kinase NLK... | 353 | 2e-55 | 196 | 33 | 53 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0004707; F:MAP kinase activity; ISS:UniProtKB.::GO:0042169; F:SH2 domain binding; ISS:UniProtKB.::GO:0008134; F:transcription factor binding; IPI:UniProtKB.::GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB. | | | | | | | | | | GO:0030178; P:negative regulation of Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0018107; P:peptidyl-threonine phosphorylation; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0033136; P:serine phosphorylation of STAT3 protein; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0007179; P:transforming growth factor beta receptor signaling pathway; IMP:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. | 157 | Q9Z2A6 | 547 | MK15_RAT Mitogen-activated protein kinase 15 ... | 305 | 2e-55 | 196 | 37 | 52 | GO:0005634; C:nucleus; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; ISS:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0008156; P:negative regulation of DNA replication; IMP:RGD.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:RGD.::GO:0045732; P:positive regulation of protein catabolic process; IMP:RGD.::GO:0001934; P:positive regulation of protein phosphorylation; IMP:RGD.::GO:0031398; P:positive regulation of protein ubiquitination; IMP:RGD.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0032355; P:response to estradiol stimulus; IMP:RGD. | 158 | D3ZSZ3 | 527 | NLK_RAT Serine/threonine-protein kinase NLK O... | 353 | 2e-55 | 196 | 33 | 53 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. | 159 | O54949 | 527 | NLK_MOUSE Serine/threonine-protein kinase NLK... | 353 | 2e-55 | 196 | 33 | 53 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0004707; F:MAP kinase activity; IDA:UniProtKB.::GO:0042169; F:SH2 domain binding; IPI:UniProtKB.::GO:0008134; F:transcription factor binding; ISS:UniProtKB.::GO:0031625; F:ubiquitin protein ligase binding; ISS:UniProtKB. | | | | | | | | | | GO:0030178; P:negative regulation of Wnt receptor signaling pathway; IMP:UniProtKB.::GO:0018107; P:peptidyl-threonine phosphorylation; IDA:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:MGI.::GO:0006355; P:regulation of transcription, DNA-dependent; IMP:UniProtKB.::GO:0033136; P:serine phosphorylation of STAT3 protein; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0007179; P:transforming growth factor beta receptor signaling pathway; ISS:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. | 160 | E2QWQ2 | 527 | NLK_CANFA Serine/threonine-protein kinase NLK... | 353 | 2e-55 | 195 | 33 | 53 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. | 161 | E1BMN8 | 534 | NLK_BOVIN Serine/threonine-protein kinase NLK... | 350 | 2e-55 | 195 | 33 | 53 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. | 162 | Q9DGE1 | 348 | MK14B_DANRE Mitogen-activated protein kinase ... | 342 | 3e-55 | 191 | 34 | 53 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006950; P:response to stress; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 163 | Q90327 | 427 | MK08A_CYPCA Mitogen-activated protein kinase ... | 386 | 5e-55 | 192 | 33 | 52 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC. | | | | | | | | | | | 164 | Q9WTU6 | 423 | MK09_MOUSE Mitogen-activated protein kinase 9... | 373 | 7e-55 | 192 | 33 | 55 | GO:0044445; C:cytosolic part; ISS:MGI.::GO:0005739; C:mitochondrion; IDA:MGI.::GO:0005634; C:nucleus; IC:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004705; F:JUN kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0031558; P:induction of apoptosis in response to chemical stimulus; IGI:MGI.::GO:0046686; P:response to cadmium ion; IGI:MGI. | 165 | A3EZ54 | 278 | HOG1_WALSE Mitogen-activated protein kinase H... | 281 | 2e-54 | 186 | 37 | 58 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 166 | Q9DGD9 | 384 | MK08_DANRE Mitogen-activated protein kinase 8... | 391 | 3e-54 | 189 | 32 | 52 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC. | | | | | | | | | | GO:0048263; P:determination of dorsal identity; IMP:MGI.::GO:0007254; P:JNK cascade; ISS:UniProtKB. | 167 | Q8QHK8 | 426 | MK08_XENLA Mitogen-activated protein kinase 8... | 378 | 5e-54 | 189 | 33 | 53 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC. | | | | | | | | | | GO:0007254; P:JNK cascade; ISS:UniProtKB.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW. | 168 | Q91Y86 | 384 | MK08_MOUSE Mitogen-activated protein kinase 8... | 373 | 7e-54 | 188 | 33 | 54 | GO:0005829; C:cytosol; IDA:MGI.::GO:0005739; C:mitochondrion; IDA:MGI.::GO:0005634; C:nucleus; IDA:MGI. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004705; F:JUN kinase activity; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0031558; P:induction of apoptosis in response to chemical stimulus; IGI:MGI.::GO:0001503; P:ossification; IMP:MGI.::GO:0018107; P:peptidyl-threonine phosphorylation; IMP:MGI.::GO:2000017; P:positive regulation of determination of dorsal identity; IDA:MGI.::GO:0046686; P:response to cadmium ion; IGI:MGI. | 169 | P53779 | 464 | MK10_HUMAN Mitogen-activated protein kinase 1... | 372 | 7e-54 | 190 | 33 | 54 | | | | | | | | | | | | | | | | | | | | | | 170 | P79996 | 382 | MK09_CHICK Mitogen-activated protein kinase 9... | 372 | 1e-53 | 187 | 33 | 55 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0035419; P:activation of MAPK activity involved in innate immune response; TAS:Reactome.::GO:0009790; P:embryo development; IDA:UniProtKB.::GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.::GO:0035681; P:toll-like receptor 15 signaling pathway; TAS:Reactome.::GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.::GO:0035682; P:toll-like receptor 21 signaling pathway; TAS:Reactome.::GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.::GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.::GO:0034146; P:toll-like receptor 5 signaling pathway; TAS:Reactome.::GO:0034154; P:toll-like receptor 7 signaling pathway; TAS:Reactome. | 171 | Q61831 | 464 | MK10_MOUSE Mitogen-activated protein kinase 1... | 372 | 1e-53 | 189 | 33 | 54 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004705; F:JUN kinase activity; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:BHF-UCL. | | | | | | | | | | | 172 | P45983 | 427 | MK08_HUMAN Mitogen-activated protein kinase 8... | 373 | 2e-53 | 188 | 33 | 54 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005654; C:nucleoplasm; TAS:Reactome. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042826; F:histone deacetylase binding; IPI:BHF-UCL.::GO:0035033; F:histone deacetylase regulator activity; IMP:BHF-UCL.::GO:0004705; F:JUN kinase activity; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0008633; P:activation of pro-apoptotic gene products; TAS:Reactome.::GO:0071260; P:cellular response to mechanical stimulus; IEP:UniProtKB.::GO:0008624; P:induction of apoptosis by extracellular signals; TAS:Reactome.::GO:0008629; P:induction of apoptosis by intracellular signals; TAS:Reactome.::GO:0045087; P:innate immune response; TAS:Reactome.::GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.::GO:0043066; P:negative regulation of apoptotic process; IDA:UniProtKB.::GO:0032091; P:negative regulation of protein binding; IDA:UniProtKB.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:UniProtKB.::GO:0018107; P:peptidyl-threonine phosphorylation; IDA:UniProtKB.::GO:0090045; P:positive regulation of deacetylase activity; IMP:BHF-UCL.::GO:0010628; P:positive regulation of gene expression; IMP:BHF-UCL.::GO:0032880; P:regulation of protein localization; IDA:BHF-UCL.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; TAS:Reactome.::GO:0009411; P:response to UV; IDA:MGI.::GO:0008063; P:Toll signaling pathway; TAS:Reactome.::GO:0034130; P:toll-like receptor 1 signaling pathway; TAS:Reactome.::GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.::GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.::GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.::GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome. | 173 | A3EZ53 | 278 | HOG1_WALMU Mitogen-activated protein kinase H... | 281 | 2e-53 | 184 | 36 | 58 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 174 | P49185 | 411 | MK08_RAT Mitogen-activated protein kinase 8 O... | 372 | 2e-53 | 187 | 33 | 54 | GO:0033267; C:axon part; IDA:RGD.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0032839; C:dendrite cytoplasm; IDA:RGD.::GO:0005739; C:mitochondrion; IDA:RGD.::GO:0005634; C:nucleus; IDA:RGD.::GO:0043204; C:perikaryon; IDA:RGD.::GO:0031982; C:vesicle; IDA:RGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004705; F:JUN kinase activity; ISS:UniProtKB.::GO:0005515; F:protein binding; IPI:RGD. | | | | | | | | | | GO:0006954; P:inflammatory response; IDA:RGD.::GO:0043066; P:negative regulation of apoptotic process; IDA:RGD.::GO:0031175; P:neuron projection development; IMP:RGD.::GO:0043065; P:positive regulation of apoptotic process; IEP:RGD.::GO:0030335; P:positive regulation of cell migration; IDA:RGD.::GO:0045740; P:positive regulation of DNA replication; IMP:RGD.::GO:0031116; P:positive regulation of microtubule polymerization; IMP:RGD.::GO:0006355; P:regulation of transcription, DNA-dependent; IDA:RGD.::GO:0009408; P:response to heat; IDA:RGD.::GO:0042542; P:response to hydrogen peroxide; IDA:RGD.::GO:0006970; P:response to osmotic stress; IDA:RGD.::GO:0048545; P:response to steroid hormone stimulus; IEP:RGD. | 175 | P49186 | 423 | MK09_RAT Mitogen-activated protein kinase 9 O... | 373 | 2e-53 | 188 | 33 | 55 | GO:0044445; C:cytosolic part; IDA:MGI.::GO:0005739; C:mitochondrion; IDA:RGD.::GO:0005634; C:nucleus; IDA:RGD. | | | | | | | | | | GO:0005524; F:ATP binding; IDA:RGD.::GO:0008656; F:cysteine-type endopeptidase activator activity involved in apoptotic process; IMP:RGD.::GO:0004705; F:JUN kinase activity; IDA:RGD.::GO:0031435; F:mitogen-activated protein kinase kinase kinase binding; IPI:RGD.::GO:0008134; F:transcription factor binding; IDA:RGD. | | | | | | | | | | GO:0071363; P:cellular response to growth factor stimulus; IEP:RGD.::GO:0071347; P:cellular response to interleukin-1; IEP:RGD.::GO:0071222; P:cellular response to lipopolysaccharide; IEP:RGD.::GO:0071356; P:cellular response to tumor necrosis factor; IEP:RGD.::GO:0034644; P:cellular response to UV; IMP:RGD.::GO:0007417; P:central nervous system development; IEP:RGD.::GO:0031175; P:neuron projection development; IMP:RGD.::GO:0043065; P:positive regulation of apoptotic process; IMP:RGD.::GO:0010770; P:positive regulation of cell morphogenesis involved in differentiation; IMP:RGD.::GO:0032722; P:positive regulation of chemokine production; IMP:RGD.::GO:0045429; P:positive regulation of nitric oxide biosynthetic process; IMP:RGD.::GO:0051770; P:positive regulation of nitric-oxide synthase biosynthetic process; IMP:RGD.::GO:0031394; P:positive regulation of prostaglandin biosynthetic process; IMP:RGD.::GO:0032308; P:positive regulation of prostaglandin secretion; IMP:RGD.::GO:0001934; P:positive regulation of protein phosphorylation; IMP:RGD.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IMP:RGD.::GO:0006626; P:protein targeting to mitochondrion; IEP:RGD.::GO:0046328; P:regulation of JNK cascade; IMP:RGD.::GO:0031396; P:regulation of protein ubiquitination; IMP:RGD.::GO:0001836; P:release of cytochrome c from mitochondria; IMP:RGD.::GO:0014075; P:response to amine stimulus; IEP:RGD.::GO:0042493; P:response to drug; IMP:RGD.::GO:0009612; P:response to mechanical stimulus; IEP:RGD.::GO:0009636; P:response to toxin; IEP:RGD. | 176 | Q9U9Y8 | 634 | NLK_CAEEL Serine/threonine kinase NLK OS=Caen... | 305 | 2e-53 | 192 | 37 | 56 | GO:0005938; C:cell cortex; IDA:WormBase.::GO:0005634; C:nucleus; IDA:WormBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0047485; F:protein N-terminus binding; IPI:UniProtKB. | | | | | | | | | | GO:0008356; P:asymmetric cell division; IMP:WormBase.::GO:0045167; P:asymmetric protein localization involved in cell fate determination; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0001714; P:endodermal cell fate specification; IMP:WormBase.::GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0007052; P:mitotic spindle organization; IMP:WormBase.::GO:0042694; P:muscle cell fate specification; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0010085; P:polarity specification of proximal/distal axis; IMP:WormBase.::GO:0016055; P:Wnt receptor signaling pathway; IGI:WormBase. | 177 | P45984 | 424 | MK09_HUMAN Mitogen-activated protein kinase 9... | 372 | 3e-53 | 187 | 33 | 55 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005654; C:nucleoplasm; TAS:Reactome. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004705; F:JUN kinase activity; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0008134; F:transcription factor binding; IDA:UniProtKB. | | | | | | | | | | GO:0045087; P:innate immune response; TAS:Reactome.::GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.::GO:0010628; P:positive regulation of gene expression; IMP:BHF-UCL.::GO:0010744; P:positive regulation of macrophage derived foam cell differentiation; IMP:BHF-UCL.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; TAS:Reactome.::GO:0008063; P:Toll signaling pathway; TAS:Reactome.::GO:0034130; P:toll-like receptor 1 signaling pathway; TAS:Reactome.::GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.::GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.::GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.::GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome. | 178 | O42099 | 427 | MK08B_CYPCA Mitogen-activated protein kinase ... | 387 | 3e-53 | 187 | 33 | 51 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC. | | | | | | | | | | | 179 | P92208 | 372 | JNK_DROME Stress-activated protein kinase JNK... | 367 | 6e-53 | 185 | 32 | 53 | GO:0030424; C:axon; IDA:FlyBase.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0030425; C:dendrite; IDA:FlyBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004705; F:JUN kinase activity; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:FlyBase. | | | | | | | | | | GO:0019731; P:antibacterial humoral response; IDA:FlyBase.::GO:0048675; P:axon extension; IMP:FlyBase.::GO:0007411; P:axon guidance; IMP:FlyBase.::GO:0007298; P:border follicle cell migration; IGI:FlyBase.::GO:0071243; P:cellular response to arsenic-containing substance; IDA:FlyBase.::GO:0071276; P:cellular response to cadmium ion; IDA:FlyBase.::GO:0034614; P:cellular response to reactive oxygen species; IDA:FlyBase.::GO:0048674; P:collateral sprouting of injured axon; IMP:FlyBase.::GO:0046843; P:dorsal appendage formation; IMP:FlyBase.::GO:0007391; P:dorsal closure; NAS:FlyBase.::GO:0001736; P:establishment of planar polarity; NAS:FlyBase.::GO:0046529; P:imaginal disc fusion, thorax closure; IMP:FlyBase.::GO:0048803; P:imaginal disc-derived male genitalia morphogenesis; IMP:FlyBase.::GO:0035006; P:melanization defense response; IMP:FlyBase.::GO:0046844; P:micropyle formation; IMP:FlyBase.::GO:0043508; P:negative regulation of JUN kinase activity; IMP:FlyBase.::GO:0009408; P:response to heat; IMP:FlyBase.::GO:0016055; P:Wnt receptor signaling pathway; NAS:FlyBase.::GO:0035313; P:wound healing, spreading of epidermal cells; IMP:FlyBase. | 180 | Q8TD08 | 544 | MK15_HUMAN Mitogen-activated protein kinase 1... | 309 | 3e-52 | 187 | 35 | 52 | GO:0005576; C:extracellular region; NAS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IDA:UniProtKB.::GO:0017124; F:SH3 domain binding; NAS:UniProtKB. | | | | | | | | | | GO:0046777; P:protein autophosphorylation; IDA:UniProtKB. | 181 | A3EZ55 | 278 | HOG1_WALIC Mitogen-activated protein kinase H... | 272 | 6e-52 | 180 | 37 | 57 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. |