| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
61 | P51635 | 325 | AK1A1_RAT Alcohol dehydrogenase [NADP(+)] OS=... | 282 | 2e-18 | 86.3 | 26 | 45 | | | | | | | | | | | | | | | | | | | | | | 62 | Q6IMN8 | 297 | ALRA_DICDI Aldose reductase A OS=Dictyosteliu... | 180 | 2e-18 | 85.9 | 36 | 51 | GO:0005829; C:cytosol; IDA:dictyBase.::GO:0005615; C:extracellular space; IDA:dictyBase.::GO:0045335; C:phagocytic vesicle; IDA:dictyBase. | | | | | | | | | | GO:0004032; F:alditol:NADP+ 1-oxidoreductase activity; IDA:dictyBase. | | | | | | | | | | GO:0006928; P:cellular component movement; IMP:dictyBase.::GO:0042593; P:glucose homeostasis; IMP:dictyBase.::GO:0031158; P:negative regulation of aggregate size involved in sorocarp development; IMP:dictyBase.::GO:0009617; P:response to bacterium; IEP:dictyBase.::GO:0006979; P:response to oxidative stress; IMP:dictyBase. | 63 | Q5REQ0 | 323 | AK1C1_PONAB Aldo-keto reductase family 1 memb... | 260 | 3e-18 | 85.9 | 24 | 46 | GO:0005829; C:cytosol; ISS:UniProtKB. | | | | | | | | | | GO:0047006; F:17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity; IEA:EC.::GO:0047042; F:androsterone dehydrogenase (B-specific) activity; ISS:UniProtKB.::GO:0032052; F:bile acid binding; ISS:UniProtKB.::GO:0047718; F:indanol dehydrogenase activity; IEA:EC.::GO:0047115; F:trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity; ISS:UniProtKB. | | | | | | | | | | GO:0008206; P:bile acid metabolic process; ISS:UniProtKB.::GO:0007586; P:digestion; ISS:UniProtKB.::GO:0051260; P:protein homooligomerization; ISS:UniProtKB. | 64 | P82809 | 322 | AK1CD_MESAU Aldo-keto reductase family 1 memb... | 268 | 3e-18 | 85.9 | 26 | 47 | | | | | | | | | | | GO:0050109; F:morphine 6-dehydrogenase activity; IEA:EC. | | | | | | | | | | GO:0009820; P:alkaloid metabolic process; IEA:UniProtKB-KW. | 65 | P52895 | 323 | AK1C2_HUMAN Aldo-keto reductase family 1 memb... | 265 | 3e-18 | 85.5 | 24 | 47 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004032; F:alditol:NADP+ 1-oxidoreductase activity; IDA:UniProtKB.::GO:0047026; F:androsterone dehydrogenase (A-specific) activity; IEA:EC.::GO:0032052; F:bile acid binding; IDA:UniProtKB.::GO:0047086; F:ketosteroid monooxygenase activity; IDA:UniProtKB.::GO:0016655; F:oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor; IDA:UniProtKB.::GO:0018636; F:phenanthrene 9,10-monooxygenase activity; IDA:UniProtKB.::GO:0004958; F:prostaglandin F receptor activity; IDA:UniProtKB.::GO:0047115; F:trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity; IDA:UniProtKB. | | | | | | | | | | GO:0016999; P:antibiotic metabolic process; IMP:UniProtKB.::GO:0071395; P:cellular response to jasmonic acid stimulus; IDA:UniProtKB.::GO:0007586; P:digestion; IDA:UniProtKB.::GO:0008284; P:positive regulation of cell proliferation; IDA:UniProtKB.::GO:0051897; P:positive regulation of protein kinase B signaling cascade; IDA:UniProtKB.::GO:0042448; P:progesterone metabolic process; IDA:UniProtKB.::GO:0006693; P:prostaglandin metabolic process; IDA:UniProtKB.::GO:0034694; P:response to prostaglandin stimulus; IDA:UniProtKB. | 66 | O70473 | 228 | AK1A1_CRIGR Alcohol dehydrogenase [NADP(+)] O... | 216 | 3e-18 | 84.7 | 29 | 48 | | | | | | | | | | | GO:0008106; F:alcohol dehydrogenase (NADP+) activity; IEA:EC. | | | | | | | | | | | 67 | P70694 | 323 | DHB5_MOUSE Estradiol 17 beta-dehydrogenase 5 ... | 269 | 4e-18 | 85.1 | 25 | 45 | | | | | | | | | | | GO:0004033; F:aldo-keto reductase (NADP) activity; IDA:MGI.::GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IDA:MGI. | | | | | | | | | | GO:0006694; P:steroid biosynthetic process; IDA:MGI. | 68 | O60218 | 316 | AK1BA_HUMAN Aldo-keto reductase family 1 memb... | 294 | 4e-18 | 85.1 | 26 | 45 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.::GO:0005764; C:lysosome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004033; F:aldo-keto reductase (NADP) activity; TAS:UniProtKB.::GO:0045550; F:geranylgeranyl reductase activity; IDA:UniProtKB.::GO:0047718; F:indanol dehydrogenase activity; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0001758; F:retinal dehydrogenase activity; IDA:UniProtKB. | | | | | | | | | | GO:0016999; P:antibiotic metabolic process; IMP:UniProtKB.::GO:0006081; P:cellular aldehyde metabolic process; TAS:ProtInc.::GO:0007586; P:digestion; TAS:ProtInc.::GO:0016488; P:farnesol catabolic process; IDA:UniProtKB.::GO:0008202; P:steroid metabolic process; TAS:ProtInc. | 69 | P14550 | 325 | AK1A1_HUMAN Alcohol dehydrogenase [NADP(+)] O... | 279 | 5e-18 | 85.1 | 25 | 46 | | | | | | | | | | | GO:0004032; F:alditol:NADP+ 1-oxidoreductase activity; TAS:ProtInc.::GO:0009055; F:electron carrier activity; TAS:UniProtKB. | | | | | | | | | | GO:0006006; P:glucose metabolic process; TAS:ProtInc. | 70 | Q10494 | 321 | YDG7_SCHPO Uncharacterized oxidoreductase C26... | 207 | 8e-18 | 84.3 | 30 | 47 | GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase. | | | | | | | | | | GO:0047935; F:glucose 1-dehydrogenase (NADP+) activity; ISS:PomBase. | | | | | | | | | | GO:0019568; P:arabinose catabolic process; ISS:PomBase.::GO:0033554; P:cellular response to stress; IEP:PomBase.::GO:0042843; P:D-xylose catabolic process; ISS:PomBase. | 71 | Q4R802 | 320 | AKCL2_MACFA 1,5-anhydro-D-fructose reductase ... | 273 | 8e-18 | 84.3 | 27 | 41 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0050571; F:1,5-anhydro-D-fructose reductase activity; IEA:EC. | | | | | | | | | | | 72 | Q9C1X5 | 283 | YKW2_SCHPO Uncharacterized oxidoreductase P32... | 226 | 1e-17 | 83.6 | 29 | 48 | GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase. | | | | | | | | | | GO:0032866; F:D-xylose:NADP reductase activity; ISS:PomBase.::GO:0032867; F:L-arabinose:NADP reductase activity; ISS:PomBase. | | | | | | | | | | GO:0019568; P:arabinose catabolic process; ISS:PomBase.::GO:0033554; P:cellular response to stress; IEP:PomBase.::GO:0042843; P:D-xylose catabolic process; ISS:PomBase. | 73 | Q95JH6 | 323 | AK1C1_MACFU Aldo-keto reductase family 1 memb... | 265 | 2e-17 | 83.6 | 24 | 45 | GO:0005829; C:cytosol; ISS:UniProtKB. | | | | | | | | | | GO:0047006; F:17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity; IEA:EC.::GO:0047042; F:androsterone dehydrogenase (B-specific) activity; ISS:UniProtKB.::GO:0032052; F:bile acid binding; ISS:UniProtKB.::GO:0047718; F:indanol dehydrogenase activity; IEA:EC.::GO:0047115; F:trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity; ISS:UniProtKB. | | | | | | | | | | GO:0008206; P:bile acid metabolic process; ISS:UniProtKB.::GO:0007586; P:digestion; ISS:UniProtKB.::GO:0051260; P:protein homooligomerization; ISS:UniProtKB. | 74 | O69462 | 282 | Y1669_MYCLE Uncharacterized oxidoreductase ML... | 161 | 2e-17 | 82.8 | 32 | 49 | | | | | | | | | | | GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 75 | B8ZS00 | 282 | Y1669_MYCLB Uncharacterized oxidoreductase ML... | 161 | 2e-17 | 82.8 | 32 | 49 | | | | | | | | | | | GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 76 | Q5R7C9 | 323 | AK1C3_PONAB Aldo-keto reductase family 1 memb... | 260 | 2e-17 | 83.2 | 24 | 47 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0047020; F:15-hydroxyprostaglandin-D dehydrogenase (NADP+) activity; ISS:UniProtKB.::GO:0004032; F:alditol:NADP+ 1-oxidoreductase activity; ISS:UniProtKB.::GO:0047026; F:androsterone dehydrogenase (A-specific) activity; IEA:EC.::GO:0047787; F:delta4-3-oxosteroid 5beta-reductase activity; ISS:UniProtKB.::GO:0035410; F:dihydrotestosterone 17-beta-dehydrogenase activity; ISS:UniProtKB.::GO:0045550; F:geranylgeranyl reductase activity; ISS:UniProtKB.::GO:0047718; F:indanol dehydrogenase activity; IEA:EC.::GO:0045703; F:ketoreductase activity; ISS:UniProtKB.::GO:0047086; F:ketosteroid monooxygenase activity; ISS:UniProtKB.::GO:0016655; F:oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor; ISS:UniProtKB.::GO:0018636; F:phenanthrene 9,10-monooxygenase activity; ISS:UniProtKB.::GO:0036131; F:prostaglandin D2 11-ketoreductase activity; IEA:EC.::GO:0004958; F:prostaglandin F receptor activity; ISS:UniProtKB.::GO:0047017; F:prostaglandin-F synthase activity; IEA:EC.::GO:0001758; F:retinal dehydrogenase activity; ISS:UniProtKB.::GO:0004745; F:retinol dehydrogenase activity; ISS:UniProtKB.::GO:0050327; F:testosterone 17-beta-dehydrogenase (NAD+) activity; IEA:EC.::GO:0047045; F:testosterone 17-beta-dehydrogenase (NADP+) activity; IEA:EC.::GO:0047115; F:trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity; IEA:EC. | | | | | | | | | | GO:0016999; P:antibiotic metabolic process; ISS:UniProtKB.::GO:0071276; P:cellular response to cadmium ion; ISS:UniProtKB.::GO:0071277; P:cellular response to calcium ion; ISS:UniProtKB.::GO:0071384; P:cellular response to corticosteroid stimulus; ISS:UniProtKB.::GO:0071395; P:cellular response to jasmonic acid stimulus; ISS:UniProtKB.::GO:0071379; P:cellular response to prostaglandin stimulus; ISS:UniProtKB.::GO:0034614; P:cellular response to reactive oxygen species; ISS:UniProtKB.::GO:0016488; P:farnesol catabolic process; ISS:UniProtKB.::GO:1900053; P:negative regulation of retinoic acid biosynthetic process; ISS:UniProtKB.::GO:0008284; P:positive regulation of cell proliferation; ISS:UniProtKB.::GO:2000353; P:positive regulation of endothelial cell apoptotic process; ISS:UniProtKB.::GO:0051897; P:positive regulation of protein kinase B signaling cascade; ISS:UniProtKB.::GO:2000379; P:positive regulation of reactive oxygen species metabolic process; ISS:UniProtKB.::GO:0042448; P:progesterone metabolic process; ISS:UniProtKB.::GO:0000060; P:protein import into nucleus, translocation; ISS:UniProtKB.::GO:0048385; P:regulation of retinoic acid receptor signaling pathway; ISS:UniProtKB.::GO:2000224; P:regulation of testosterone biosynthetic process; ISS:UniProtKB.::GO:0042574; P:retinal metabolic process; ISS:UniProtKB.::GO:0061370; P:testosterone biosynthetic process; ISS:UniProtKB. | 77 | Q8VCX1 | 325 | AK1D1_MOUSE 3-oxo-5-beta-steroid 4-dehydrogen... | 253 | 3e-17 | 82.8 | 27 | 45 | | | | | | | | | | | GO:0047787; F:delta4-3-oxosteroid 5beta-reductase activity; IEA:EC. | | | | | | | | | | GO:0030573; P:bile acid catabolic process; IEA:UniProtKB-KW. | 78 | O34678 | 280 | YTBE_BACSU Uncharacterized oxidoreductase Ytb... | 232 | 4e-17 | 82 | 28 | 51 | | | | | | | | | | | GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 79 | Q3ZCJ2 | 325 | AK1A1_BOVIN Alcohol dehydrogenase [NADP(+)] O... | 279 | 5e-17 | 82 | 24 | 44 | | | | | | | | | | | | | | | | | | | | | | 80 | Q96JD6 | 320 | AKCL2_HUMAN 1,5-anhydro-D-fructose reductase ... | 273 | 7e-17 | 81.6 | 27 | 41 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0050571; F:1,5-anhydro-D-fructose reductase activity; IEA:EC. | | | | | | | | | | | 81 | Q6GMC7 | 327 | AK1A1_XENLA Alcohol dehydrogenase [NADP(+)] O... | 260 | 8e-17 | 81.6 | 26 | 49 | | | | | | | | | | | GO:0008106; F:alcohol dehydrogenase (NADP+) activity; IEA:EC. | | | | | | | | | | | 82 | A3PXT0 | 276 | Y1919_MYCSJ Uncharacterized oxidoreductase Mj... | 220 | 8e-17 | 80.9 | 28 | 48 | | | | | | | | | | | GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 83 | A1UEC6 | 276 | Y1985_MYCSK Uncharacterized oxidoreductase Mk... | 220 | 8e-17 | 80.9 | 28 | 48 | | | | | | | | | | | GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 84 | P42330 | 323 | AK1C3_HUMAN Aldo-keto reductase family 1 memb... | 260 | 9e-17 | 81.6 | 23 | 47 | GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB. | | | | | | | | | | GO:0047020; F:15-hydroxyprostaglandin-D dehydrogenase (NADP+) activity; IDA:UniProtKB.::GO:0004032; F:alditol:NADP+ 1-oxidoreductase activity; IDA:UniProtKB.::GO:0047026; F:androsterone dehydrogenase (A-specific) activity; IEA:EC.::GO:0047787; F:delta4-3-oxosteroid 5beta-reductase activity; IDA:UniProtKB.::GO:0035410; F:dihydrotestosterone 17-beta-dehydrogenase activity; IDA:UniProtKB.::GO:0045550; F:geranylgeranyl reductase activity; IDA:UniProtKB.::GO:0047718; F:indanol dehydrogenase activity; IEA:EC.::GO:0045703; F:ketoreductase activity; IDA:UniProtKB.::GO:0047086; F:ketosteroid monooxygenase activity; IDA:UniProtKB.::GO:0016655; F:oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor; IDA:UniProtKB.::GO:0018636; F:phenanthrene 9,10-monooxygenase activity; IDA:UniProtKB.::GO:0036131; F:prostaglandin D2 11-ketoreductase activity; IEA:EC.::GO:0004958; F:prostaglandin F receptor activity; IDA:UniProtKB.::GO:0047017; F:prostaglandin-F synthase activity; IEA:EC.::GO:0001758; F:retinal dehydrogenase activity; IDA:UniProtKB.::GO:0004745; F:retinol dehydrogenase activity; IDA:UniProtKB.::GO:0050327; F:testosterone 17-beta-dehydrogenase (NAD+) activity; IEA:EC.::GO:0047045; F:testosterone 17-beta-dehydrogenase (NADP+) activity; IEA:EC.::GO:0047115; F:trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity; IEA:EC. | | | | | | | | | | GO:0016999; P:antibiotic metabolic process; IMP:UniProtKB.::GO:0071276; P:cellular response to cadmium ion; IDA:UniProtKB.::GO:0071277; P:cellular response to calcium ion; IDA:UniProtKB.::GO:0071384; P:cellular response to corticosteroid stimulus; IDA:UniProtKB.::GO:0071395; P:cellular response to jasmonic acid stimulus; IDA:UniProtKB.::GO:0071379; P:cellular response to prostaglandin stimulus; IDA:UniProtKB.::GO:0034614; P:cellular response to reactive oxygen species; IDA:UniProtKB.::GO:0009267; P:cellular response to starvation; IEP:UniProtKB.::GO:0016488; P:farnesol catabolic process; IDA:UniProtKB.::GO:0030216; P:keratinocyte differentiation; IEP:UniProtKB.::GO:0008584; P:male gonad development; IEP:UniProtKB.::GO:0044259; P:multicellular organismal macromolecule metabolic process; IEP:UniProtKB.::GO:1900053; P:negative regulation of retinoic acid biosynthetic process; IDA:UniProtKB.::GO:0008284; P:positive regulation of cell proliferation; IDA:UniProtKB.::GO:2000353; P:positive regulation of endothelial cell apoptotic process; IDA:UniProtKB.::GO:0051897; P:positive regulation of protein kinase B signaling cascade; IDA:UniProtKB.::GO:2000379; P:positive regulation of reactive oxygen species metabolic process; IDA:UniProtKB.::GO:0042448; P:progesterone metabolic process; IDA:UniProtKB.::GO:0000060; P:protein import into nucleus, translocation; IDA:UniProtKB.::GO:0048385; P:regulation of retinoic acid receptor signaling pathway; IDA:UniProtKB.::GO:2000224; P:regulation of testosterone biosynthetic process; IMP:UniProtKB.::GO:0070293; P:renal absorption; NAS:UniProtKB.::GO:0007584; P:response to nutrient; IEP:UniProtKB.::GO:0042574; P:retinal metabolic process; IDA:UniProtKB.::GO:0061370; P:testosterone biosynthetic process; IMP:UniProtKB. | 85 | P23457 | 322 | DIDH_RAT 3-alpha-hydroxysteroid dehydrogenase... | 279 | 9e-17 | 81.3 | 24 | 43 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0047026; F:androsterone dehydrogenase (A-specific) activity; IEA:EC. | | | | | | | | | | GO:0021766; P:hippocampus development; IEP:RGD.::GO:0008202; P:steroid metabolic process; TAS:RGD. | 86 | Q95JH7 | 323 | AK1C1_MACFA Aldo-keto reductase family 1 memb... | 265 | 9e-17 | 81.3 | 24 | 45 | GO:0005829; C:cytosol; ISS:UniProtKB. | | | | | | | | | | GO:0047006; F:17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity; IEA:EC.::GO:0047042; F:androsterone dehydrogenase (B-specific) activity; ISS:UniProtKB.::GO:0032052; F:bile acid binding; ISS:UniProtKB.::GO:0047718; F:indanol dehydrogenase activity; IEA:EC.::GO:0047115; F:trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity; ISS:UniProtKB. | | | | | | | | | | GO:0008206; P:bile acid metabolic process; ISS:UniProtKB.::GO:0007586; P:digestion; ISS:UniProtKB.::GO:0051260; P:protein homooligomerization; ISS:UniProtKB. | 87 | Q8ZM06 | 275 | DKGA_SALTY 2,5-diketo-D-gluconic acid reducta... | 256 | 1e-16 | 80.5 | 28 | 47 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0050580; F:2,5-didehydrogluconate reductase activity; IEA:EC. | | | | | | | | | | GO:0019853; P:L-ascorbic acid biosynthetic process; IEA:UniProtKB-KW. | 88 | P82125 | 301 | AKCL2_PIG 1,5-anhydro-D-fructose reductase OS... | 252 | 1e-16 | 80.9 | 26 | 43 | | | | | | | | | | | GO:0050571; F:1,5-anhydro-D-fructose reductase activity; IEA:EC. | | | | | | | | | | | 89 | Q9JII6 | 325 | AK1A1_MOUSE Alcohol dehydrogenase [NADP(+)] O... | 282 | 2e-16 | 80.5 | 25 | 44 | GO:0016324; C:apical plasma membrane; IDA:MGI.::GO:0005829; C:cytosol; IDA:MGI. | | | | | | | | | | GO:0004032; F:alditol:NADP+ 1-oxidoreductase activity; IDA:MGI.::GO:0047939; F:L-glucuronate reductase activity; IDA:MGI. | | | | | | | | | | GO:0046185; P:aldehyde catabolic process; IDA:MGI.::GO:0042840; P:D-glucuronate catabolic process; IDA:MGI.::GO:0019853; P:L-ascorbic acid biosynthetic process; IDA:MGI. | 90 | Q9USV2 | 276 | YHH5_SCHPO Uncharacterized oxidoreductase C28... | 208 | 2e-16 | 79.7 | 31 | 50 | GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase. | | | | | | | | | | GO:0032866; F:D-xylose:NADP reductase activity; ISS:PomBase.::GO:0032867; F:L-arabinose:NADP reductase activity; ISS:PomBase. | | | | | | | | | | GO:0019568; P:arabinose catabolic process; ISS:PomBase.::GO:0042843; P:D-xylose catabolic process; ISS:PomBase. | 91 | Q568L5 | 324 | A1A1B_DANRE Alcohol dehydrogenase [NADP(+)] B... | 253 | 2e-16 | 80.5 | 26 | 46 | | | | | | | | | | | GO:0008106; F:alcohol dehydrogenase (NADP+) activity; IEA:EC. | | | | | | | | | | |
