| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | Q8C4S8 | 1000 | DEN2A_MOUSE DENN domain-containing protein 2A... | 31 | 1.5 | 35 | 45 | 74 | | | | | | | | | | | | | | | | | | | | | | 2 | Q9H2X6 | 1198 | HIPK2_HUMAN Homeodomain-interacting protein k... | 43 | 2 | 34.7 | 35 | 56 | GO:0005813; C:centrosome; IDA:HPA.::GO:0031965; C:nuclear membrane; IDA:HPA.::GO:0016605; C:PML body; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:BHF-UCL.::GO:0001102; F:RNA polymerase II activating transcription factor binding; ISS:BHF-UCL.::GO:0046332; F:SMAD binding; IPI:UniProtKB.::GO:0003714; F:transcription corepressor activity; IDA:UniProtKB.::GO:0046790; F:virion binding; IPI:UniProtKB. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0071456; P:cellular response to hypoxia; TAS:UniProtKB.::GO:0042771; P:DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis; TAS:UniProtKB.::GO:0006978; P:DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator; IDA:BHF-UCL.::GO:0030218; P:erythrocyte differentiation; ISS:UniProtKB.::GO:0030514; P:negative regulation of BMP signaling pathway; IMP:UniProtKB.::GO:0018105; P:peptidyl-serine phosphorylation; ISS:BHF-UCL.::GO:0018107; P:peptidyl-threonine phosphorylation; ISS:BHF-UCL.::GO:0030578; P:PML body organization; TAS:UniProtKB.::GO:0045766; P:positive regulation of angiogenesis; IDA:UniProtKB.::GO:0046330; P:positive regulation of JNK cascade; IMP:UniProtKB.::GO:0032092; P:positive regulation of protein binding; ISS:BHF-UCL.::GO:0051091; P:positive regulation of sequence-specific DNA binding transcription factor activity; ISS:BHF-UCL.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:BHF-UCL.::GO:0030511; P:positive regulation of transforming growth factor beta receptor signaling pathway; IMP:UniProtKB.::GO:0051726; P:regulation of cell cycle; TAS:UniProtKB.::GO:0060395; P:SMAD protein signal transduction; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0019048; P:virus-host interaction; NAS:UniProtKB. | 3 | Q9QZR5 | 1196 | HIPK2_MOUSE Homeodomain-interacting protein k... | 43 | 2.1 | 34.7 | 35 | 56 | GO:0016605; C:PML body; TAS:MGI. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IDA:BHF-UCL.::GO:0001102; F:RNA polymerase II activating transcription factor binding; IPI:BHF-UCL.::GO:0003714; F:transcription corepressor activity; IDA:UniProtKB.::GO:0046790; F:virion binding; ISS:UniProtKB. | | | | | | | | | | GO:0007628; P:adult walking behavior; IMP:MGI.::GO:0009952; P:anterior/posterior pattern specification; IGI:MGI.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0048596; P:embryonic camera-type eye morphogenesis; IMP:DFLAT.::GO:0060059; P:embryonic retina morphogenesis in camera-type eye; IMP:DFLAT.::GO:0061072; P:iris morphogenesis; IMP:DFLAT.::GO:0060235; P:lens induction in camera-type eye; IMP:DFLAT.::GO:0043524; P:negative regulation of neuron apoptotic process; IMP:MGI.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0030182; P:neuron differentiation; IMP:DFLAT.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:BHF-UCL.::GO:0018107; P:peptidyl-threonine phosphorylation; IDA:BHF-UCL.::GO:0008284; P:positive regulation of cell proliferation; IGI:MGI.::GO:0043388; P:positive regulation of DNA binding; IDA:UniProtKB.::GO:0046330; P:positive regulation of JNK cascade; ISS:UniProtKB.::GO:0032092; P:positive regulation of protein binding; IDA:BHF-UCL.::GO:0051091; P:positive regulation of sequence-specific DNA binding transcription factor activity; IDA:BHF-UCL.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.::GO:0030511; P:positive regulation of transforming growth factor beta receptor signaling pathway; ISS:UniProtKB.::GO:0010842; P:retina layer formation; IMP:DFLAT.::GO:0007224; P:smoothened signaling pathway; IGI:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0007179; P:transforming growth factor beta receptor signaling pathway; IMP:MGI.::GO:0050882; P:voluntary musculoskeletal movement; IMP:MGI. | 4 | Q9WUM7 | 1168 | HIPK2_MESAU Homeodomain-interacting protein k... | 43 | 2.2 | 34.7 | 35 | 56 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016605; C:PML body; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006974; P:response to DNA damage stimulus; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. |
