Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Blastomyces dermatitidis ER-3
Locus:
BDCG_00870
Length:
552
Number of sequences:
9522
Description:
protein-tyrosine phosphatase 2
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
61Q05909    1442   PTPRG_MOUSE Receptor-type tyrosine-protein ph...2200.0000000000001     77.8     28     43GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0042802; F:identical protein binding; ISS:UniProtKB.::GO:0004725; F:protein tyrosine phosphatase activity; ISS:UniProtKB.
62P23470    1445   PTPRG_HUMAN Receptor-type tyrosine-protein ph...2200.0000000000001     77.8     28     43GO:0005887; C:integral to plasma membrane; TAS:ProtInc.
GO:0042802; F:identical protein binding; IPI:UniProtKB.::GO:0005001; F:transmembrane receptor protein tyrosine phosphatase activity; TAS:ProtInc.
GO:0007169; P:transmembrane receptor protein tyrosine kinase signaling pathway; TAS:ProtInc.
63P43378    593   PTN9_HUMAN Tyrosine-protein phosphatase non-r...2210.0000000000002     76.6     29     43GO:0044444; C:cytoplasmic part; IDA:UniProtKB.
GO:0004726; F:non-membrane spanning protein tyrosine phosphatase activity; TAS:ProtInc.::GO:0005515; F:protein binding; IPI:IntAct.
64O82656    340   PTP1_ARATH Protein-tyrosine-phosphatase PTP1 ...2160.0000000000002     75.1     30     45GO:0005737; C:cytoplasm; IDA:TAIR.::GO:0005634; C:nucleus; IDA:TAIR.::GO:0005886; C:plasma membrane; IDA:TAIR.
GO:0004725; F:protein tyrosine phosphatase activity; IEA:InterPro.
GO:0007243; P:intracellular protein kinase cascade; TAS:TAIR.
65P06800    1291   PTPRC_MOUSE Receptor-type tyrosine-protein ph...2370.000004     53.5     27     41GO:0009897; C:external side of plasma membrane; IDA:MGI.::GO:0005925; C:focal adhesion; IDA:UniProtKB.::GO:0005887; C:integral to plasma membrane; ISS:UniProtKB.::GO:0045121; C:membrane raft; IEA:UniProtKB-SubCell.
GO:0043395; F:heparan sulfate proteoglycan binding; IDA:MGI.::GO:0008201; F:heparin binding; IDA:MGI.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0004725; F:protein tyrosine phosphatase activity; ISS:UniProtKB.
GO:0000187; P:activation of MAPK activity; IMP:MGI.::GO:0030183; P:B cell differentiation; IMP:MGI.::GO:0042100; P:B cell proliferation; IMP:UniProtKB.::GO:0050853; P:B cell receptor signaling pathway; IMP:UniProtKB.::GO:0051607; P:defense response to virus; IMP:UniProtKB.::GO:0034113; P:heterotypic cell-cell adhesion; IMP:MGI.::GO:0007159; P:leukocyte cell-cell adhesion; IMP:MGI.::GO:0001960; P:negative regulation of cytokine-mediated signaling pathway; IDA:UniProtKB.::GO:0050732; P:negative regulation of peptidyl-tyrosine phosphorylation; IMP:MGI.::GO:0031953; P:negative regulation of protein autophosphorylation; IMP:MGI.::GO:0006469; P:negative regulation of protein kinase activity; IDA:UniProtKB.::GO:0001915; P:negative regulation of T cell mediated cytotoxicity; IMP:UniProtKB.::GO:0045060; P:negative thymic T cell selection; IMP:MGI.::GO:0046641; P:positive regulation of alpha-beta T cell proliferation; IMP:MGI.::GO:0050857; P:positive regulation of antigen receptor-mediated signaling pathway; IMP:UniProtKB.::GO:0043065; P:positive regulation of apoptotic process; IMP:MGI.::GO:0030890; P:positive regulation of B cell proliferation; IMP:MGI.::GO:0045588; P:positive regulation of gamma-delta T cell differentiation; IMP:MGI.::GO:0002925; P:positive regulation of humoral immune response mediated by circulating immunoglobulin; IMP:MGI.::GO:0048304; P:positive regulation of isotype switching to IgG isotypes; IMP:MGI.::GO:0043410; P:positive regulation of MAPK cascade; IMP:MGI.::GO:0001916; P:positive regulation of T cell mediated cytotoxicity; IMP:MGI.::GO:0045059; P:positive thymic T cell selection; IMP:MGI.::GO:0045577; P:regulation of B cell differentiation; IMP:MGI.::GO:0050855; P:regulation of B cell receptor signaling pathway; IMP:MGI.::GO:0051726; P:regulation of cell cycle; IDA:UniProtKB.::GO:0051209; P:release of sequestered calcium ion into cytosol; IDA:UniProtKB.::GO:0042098; P:T cell proliferation; IMP:MGI.::GO:0050852; P:T cell receptor signaling pathway; ISS:UniProtKB.
66P35822    1457   PTPRK_MOUSE Receptor-type tyrosine-protein ph...1130.0001     48.9     27     46GO:0030424; C:axon; IDA:MGI.::GO:0030425; C:dendrite; IDA:MGI.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0043025; C:neuronal cell body; IDA:MGI.::GO:0001750; C:photoreceptor outer segment; IDA:MGI.
GO:0004725; F:protein tyrosine phosphatase activity; IDA:MGI.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.
67P41499    597   PTN11_RAT Tyrosine-protein phosphatase non-re...2100.0000000000006     75.1     32     48GO:0005829; C:cytosol; IDA:RGD.::GO:0005739; C:mitochondrion; IDA:RGD.::GO:0043234; C:protein complex; IDA:RGD.::GO:0005625; C:soluble fraction; IDA:RGD.
GO:0005158; F:insulin receptor binding; IDA:RGD.::GO:0043560; F:insulin receptor substrate binding; IPI:RGD.::GO:0004726; F:non-membrane spanning protein tyrosine phosphatase activity; ISS:UniProtKB.::GO:0043274; F:phospholipase binding; IDA:RGD.::GO:0019904; F:protein domain specific binding; IPI:RGD.
GO:0048013; P:ephrin receptor signaling pathway; ISS:UniProtKB.::GO:0033628; P:regulation of cell adhesion mediated by integrin; ISS:UniProtKB.
68Q06124    597   PTN11_HUMAN Tyrosine-protein phosphatase non-...2100.0000000000007     74.7     32     49GO:0005829; C:cytosol; TAS:Reactome.
GO:0004726; F:non-membrane spanning protein tyrosine phosphatase activity; IMP:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0007411; P:axon guidance; TAS:Reactome.::GO:0007596; P:blood coagulation; TAS:Reactome.::GO:0048013; P:ephrin receptor signaling pathway; IDA:UniProtKB.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.::GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.::GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.::GO:0050900; P:leukocyte migration; TAS:Reactome.::GO:0033628; P:regulation of cell adhesion mediated by integrin; IMP:UniProtKB.::GO:0060334; P:regulation of interferon-gamma-mediated signaling pathway; TAS:Reactome.::GO:0060338; P:regulation of type I interferon-mediated signaling pathway; TAS:Reactome.::GO:0031295; P:T cell costimulation; TAS:Reactome.::GO:0060337; P:type I interferon-mediated signaling pathway; TAS:Reactome.
69Q15262    1439   PTPRK_HUMAN Receptor-type tyrosine-protein ph...1130.0001     48.9     27     46GO:0005912; C:adherens junction; IEA:UniProtKB-SubCell.::GO:0009986; C:cell surface; IDA:UniProtKB.::GO:0005911; C:cell-cell junction; IDA:UniProtKB.::GO:0005887; C:integral to plasma membrane; NAS:UniProtKB.::GO:0031256; C:leading edge membrane; IDA:UniProtKB.
GO:0008013; F:beta-catenin binding; IPI:UniProtKB.::GO:0045295; F:gamma-catenin binding; IPI:UniProtKB.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0005001; F:transmembrane receptor protein tyrosine phosphatase activity; NAS:UniProtKB.
GO:0016477; P:cell migration; IMP:UniProtKB.::GO:0034614; P:cellular response to reactive oxygen species; IDA:UniProtKB.::GO:0034644; P:cellular response to UV; IDA:UniProtKB.::GO:0048041; P:focal adhesion assembly; IMP:UniProtKB.::GO:0045786; P:negative regulation of cell cycle; IDA:UniProtKB.::GO:0030336; P:negative regulation of cell migration; IDA:UniProtKB.::GO:0010839; P:negative regulation of keratinocyte proliferation; IDA:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0034394; P:protein localization at cell surface; IDA:UniProtKB.::GO:0007179; P:transforming growth factor beta receptor signaling pathway; IDA:UniProtKB.
70P35235    597   PTN11_MOUSE Tyrosine-protein phosphatase non-...2100.0000000000008     74.7     32     48GO:0005829; C:cytosol; TAS:Reactome.
GO:0004726; F:non-membrane spanning protein tyrosine phosphatase activity; ISS:UniProtKB.::GO:0051428; F:peptide hormone receptor binding; IPI:MGI.::GO:0030971; F:receptor tyrosine kinase binding; IPI:UniProtKB.
GO:0000187; P:activation of MAPK activity; IMP:MGI.::GO:0007409; P:axonogenesis; IMP:MGI.::GO:0000077; P:DNA damage checkpoint; IMP:MGI.::GO:0048013; P:ephrin receptor signaling pathway; ISS:UniProtKB.::GO:0042593; P:glucose homeostasis; IMP:MGI.::GO:0042445; P:hormone metabolic process; IMP:MGI.::GO:0009755; P:hormone-mediated signaling pathway; IDA:MGI.::GO:0048609; P:multicellular organismal reproductive process; IMP:MGI.::GO:0051463; P:negative regulation of cortisol secretion; IMP:MGI.::GO:0060125; P:negative regulation of growth hormone secretion; IMP:MGI.::GO:0046676; P:negative regulation of insulin secretion; IMP:MGI.::GO:0048011; P:nerve growth factor receptor signaling pathway; IMP:MGI.::GO:0035265; P:organ growth; IMP:MGI.::GO:0046887; P:positive regulation of hormone secretion; IMP:MGI.::GO:0009967; P:positive regulation of signal transduction; IMP:MGI.::GO:0033628; P:regulation of cell adhesion mediated by integrin; ISS:UniProtKB.::GO:0040014; P:regulation of multicellular organism growth; IMP:MGI.::GO:0046825; P:regulation of protein export from nucleus; IMP:MGI.::GO:0006641; P:triglyceride metabolic process; IMP:MGI.
71Q98936    1422   PTPRG_CHICK Receptor-type tyrosine-protein ph...1530.059     40     28     45GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
72Q9Y2R2    807   PTN22_HUMAN Tyrosine-protein phosphatase non-...2080.0000000000009     74.7     27     44GO:0009898; C:internal side of plasma membrane; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IDA:BHF-UCL.
GO:0019900; F:kinase binding; ISS:BHF-UCL.::GO:0004725; F:protein tyrosine phosphatase activity; IDA:UniProtKB.::GO:0017124; F:SH3 domain binding; ISS:BHF-UCL.
GO:0050868; P:negative regulation of T cell activation; IMP:BHF-UCL.::GO:0050860; P:negative regulation of T cell receptor signaling pathway; IDA:UniProtKB.::GO:0035644; P:phosphoanandamide dephosphorylation; ISS:BHF-UCL.::GO:0050855; P:regulation of B cell receptor signaling pathway; NAS:BHF-UCL.::GO:0045088; P:regulation of innate immune response; IC:BHF-UCL.::GO:0032817; P:regulation of natural killer cell proliferation; IDA:BHF-UCL.::GO:0030217; P:T cell differentiation; ISS:BHF-UCL.
73P29352    802   PTN22_MOUSE Tyrosine-protein phosphatase non-...2210.000000000001     74.3     26     44GO:0009898; C:internal side of plasma membrane; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; ISS:BHF-UCL.
GO:0019900; F:kinase binding; IPI:BHF-UCL.::GO:0004725; F:protein tyrosine phosphatase activity; ISS:UniProtKB.::GO:0017124; F:SH3 domain binding; IPI:BHF-UCL.
GO:0050868; P:negative regulation of T cell activation; IMP:BHF-UCL.::GO:0050860; P:negative regulation of T cell receptor signaling pathway; ISS:UniProtKB.::GO:0035644; P:phosphoanandamide dephosphorylation; IDA:BHF-UCL.::GO:0032817; P:regulation of natural killer cell proliferation; ISS:BHF-UCL.::GO:0030217; P:T cell differentiation; IMP:MGI.::GO:0050852; P:T cell receptor signaling pathway; IMP:MGI.
74Q15256    657   PTPRR_HUMAN Receptor-type tyrosine-protein ph...2210.000000000002     73.9     28     41GO:0009986; C:cell surface; IDA:UniProtKB.::GO:0005794; C:Golgi apparatus; IDA:HPA.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005634; C:nucleus; IDA:HPA.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0019901; F:protein kinase binding; ISS:UniProtKB.::GO:0005001; F:transmembrane receptor protein tyrosine phosphatase activity; TAS:ProtInc.
GO:0001701; P:in utero embryonic development; IEP:UniProtKB.
75O08617    656   PTPRR_RAT Receptor-type tyrosine-protein phos...2060.000000000002     73.6     29     41GO:0009986; C:cell surface; ISS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0004725; F:protein tyrosine phosphatase activity; TAS:RGD.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.
GO:0001701; P:in utero embryonic development; ISS:UniProtKB.::GO:0030182; P:neuron differentiation; IEP:RGD.
76O13016    434   PTN1_CHICK Tyrosine-protein phosphatase non-r...2210.000000000003     72.4     29     47GO:0005769; C:early endosome; ISS:UniProtKB.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
GO:0004725; F:protein tyrosine phosphatase activity; ISS:UniProtKB.
GO:0031532; P:actin cytoskeleton reorganization; ISS:UniProtKB.::GO:0030968; P:endoplasmic reticulum unfolded protein response; ISS:UniProtKB.::GO:0030100; P:regulation of endocytosis; ISS:UniProtKB.::GO:0009966; P:regulation of signal transduction; ISS:UniProtKB.
77Q9IBD8    1216   PTPRC_CYPCA Receptor-type tyrosine-protein ph...2220.00007     49.7     28     40GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
GO:0050852; P:T cell receptor signaling pathway; IEA:InterPro.
78P54830    541   PTN5_MOUSE Tyrosine-protein phosphatase non-r...2070.000000000003     72.8     29     45GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0004725; F:protein tyrosine phosphatase activity; IMP:MGI.
79O14522    1441   PTPRT_HUMAN Receptor-type tyrosine-protein ph...1190.000001     55.1     29     45GO:0009986; C:cell surface; IDA:UniProtKB.::GO:0016021; C:integral to membrane; NAS:UniProtKB.::GO:0005886; C:plasma membrane; IDA:UniProtKB.
GO:0045294; F:alpha-catenin binding; IDA:UniProtKB.::GO:0008013; F:beta-catenin binding; IPI:UniProtKB.::GO:0045296; F:cadherin binding; IPI:UniProtKB.::GO:0070097; F:delta-catenin binding; IPI:UniProtKB.::GO:0045295; F:gamma-catenin binding; IDA:UniProtKB.::GO:0004725; F:protein tyrosine phosphatase activity; IMP:UniProtKB.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.
GO:0007156; P:homophilic cell adhesion; IDA:UniProtKB.::GO:0007169; P:transmembrane receptor protein tyrosine kinase signaling pathway; IMP:UniProtKB.
80Q99M80    1454   PTPRT_MOUSE Receptor-type tyrosine-protein ph...1190.000001     55.1     29     45GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; TAS:Reactome.
GO:0051393; F:alpha-actinin binding; IDA:MGI.::GO:0045294; F:alpha-catenin binding; IDA:MGI.::GO:0008013; F:beta-catenin binding; IDA:MGI.::GO:0045296; F:cadherin binding; IPI:MGI.::GO:0070097; F:delta-catenin binding; IPI:MGI.::GO:0045295; F:gamma-catenin binding; IPI:MGI.::GO:0004725; F:protein tyrosine phosphatase activity; IMP:MGI.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.::GO:0016790; F:thiolester hydrolase activity; IDA:MGI.
81P35234    369   PTN5_RAT Tyrosine-protein phosphatase non-rec...2070.000000000005     71.2     29     45GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
82Q9H3S7    1636   PTN23_HUMAN Tyrosine-protein phosphatase non-...2210.000000000006     72.4     27     44GO:0005929; C:cilium; IEA:UniProtKB-KW.::GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0005768; C:endosome; IDA:UniProtKB.::GO:0005932; C:microtubule basal body; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
GO:0060271; P:cilium morphogenesis; IMP:UniProtKB.
83Q62132    656   PTPRR_MOUSE Receptor-type tyrosine-protein ph...2060.000000000006     72     29     41GO:0009986; C:cell surface; ISS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0019901; F:protein kinase binding; IDA:UniProtKB.::GO:0004725; F:protein tyrosine phosphatase activity; IDA:MGI.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.
GO:0001701; P:in utero embryonic development; ISS:UniProtKB.
84O88902    1499   PTN23_RAT Tyrosine-protein phosphatase non-re...2210.000000000008     72     26     44GO:0005929; C:cilium; IEA:UniProtKB-KW.::GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0005768; C:endosome; ISS:UniProtKB.::GO:0005932; C:microtubule basal body; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
GO:0060271; P:cilium morphogenesis; ISS:UniProtKB.
85Q6PB44    1692   PTN23_MOUSE Tyrosine-protein phosphatase non-...2210.000000000008     72     27     43GO:0005929; C:cilium; IEA:UniProtKB-KW.::GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0005768; C:endosome; ISS:UniProtKB.::GO:0005932; C:microtubule basal body; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
GO:0060271; P:cilium morphogenesis; ISS:UniProtKB.
86Q61152    453   PTN18_MOUSE Tyrosine-protein phosphatase non-...2290.00000000001     70.9     28     42GO:0005737; C:cytoplasm; IDA:MGI.::GO:0005634; C:nucleus; IDA:MGI.
GO:0004726; F:non-membrane spanning protein tyrosine phosphatase activity; IDA:MGI.::GO:0005515; F:protein binding; IPI:MGI.
87P54829    565   PTN5_HUMAN Tyrosine-protein phosphatase non-r...2100.00000000001     70.9     29     45GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; TAS:UniProtKB.
GO:0001784; F:phosphotyrosine binding; IDA:UniProtKB.::GO:0004725; F:protein tyrosine phosphatase activity; TAS:UniProtKB.
88Q64612    1711   PTPRV_RAT Receptor-type tyrosine-protein phos...2090.00000000001     71.2     33     46GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
GO:0046849; P:bone remodeling; IEP:RGD.
89Q99952    460   PTN18_HUMAN Tyrosine-protein phosphatase non-...2290.00000000002     69.7     25     46GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0004726; F:non-membrane spanning protein tyrosine phosphatase activity; TAS:ProtInc.
90Q15678    1187   PTN14_HUMAN Tyrosine-protein phosphatase non-...2160.00000000002     70.5     28     42GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
GO:0004725; F:protein tyrosine phosphatase activity; TAS:ProtInc.::GO:0030971; F:receptor tyrosine kinase binding; IPI:UniProtKB.
GO:0001946; P:lymphangiogenesis; IMP:UniProtKB.
91B1AUH1    1446   PTPRU_MOUSE Receptor-type tyrosine-protein ph...1180.00003     50.8     28     46GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0008013; F:beta-catenin binding; IPI:MGI.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0034109; P:homotypic cell-cell adhesion; IDA:MGI.
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