rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
31 | P28827 | 1452 | PTPRM_HUMAN Receptor-type tyrosine-protein ph... | 117 | 0.002 | 44.7 | 28 | 44 | GO:0005913; C:cell-cell adherens junction; IDA:UniProtKB.::GO:0005887; C:integral to plasma membrane; NAS:UniProtKB.::GO:0030027; C:lamellipodium; IDA:MGI.::GO:0048471; C:perinuclear region of cytoplasm; IDA:UniProtKB. | | | | | | | | | | GO:0045296; F:cadherin binding; IDA:UniProtKB.::GO:0005001; F:transmembrane receptor protein tyrosine phosphatase activity; IDA:UniProtKB. | | | | | | | | | | GO:0007156; P:homophilic cell adhesion; IDA:UniProtKB.::GO:0016525; P:negative regulation of angiogenesis; IMP:UniProtKB.::GO:0010596; P:negative regulation of endothelial cell migration; IMP:UniProtKB.::GO:0001937; P:negative regulation of endothelial cell proliferation; IMP:UniProtKB.::GO:0042493; P:response to drug; IDA:UniProtKB.::GO:0010842; P:retina layer formation; IMP:UniProtKB.::GO:0031290; P:retinal ganglion cell axon guidance; IDA:UniProtKB. | 32 | P32587 | 303 | PYP3_SCHPO Tyrosine-protein phosphatase 3 OS=... | 220 | 0.000000000000004 | 79.7 | 27 | 44 | GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IDA:PomBase. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0007346; P:regulation of mitotic cell cycle; IMP:PomBase.::GO:0007165; P:signal transduction; IC:PomBase. | 33 | A4IFW2 | 1909 | PTPRF_DANRE Receptor-type tyrosine-protein ph... | 215 | 0.0000000000003 | 77 | 30 | 46 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007155; P:cell adhesion; IEA:UniProtKB-KW. | 34 | P18052 | 829 | PTPRA_MOUSE Receptor-type tyrosine-protein ph... | 218 | 0.000000000006 | 72.4 | 28 | 45 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC. | | | | | | | | | | GO:0008286; P:insulin receptor signaling pathway; IMP:MGI.::GO:0006468; P:protein phosphorylation; IDA:MGI. | 35 | Q64455 | 1238 | PTPRJ_MOUSE Receptor-type tyrosine-protein ph... | 215 | 0.000000000000005 | 82.4 | 29 | 47 | GO:0005911; C:cell-cell junction; ISS:UniProtKB.::GO:0001772; C:immunological synapse; IDA:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0032587; C:ruffle membrane; IDA:UniProtKB. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IMP:UniProtKB. | | | | | | | | | | GO:0007596; P:blood coagulation; IMP:UniProtKB.::GO:0007507; P:heart development; IMP:MGI.::GO:0030336; P:negative regulation of cell migration; IDA:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; IMP:UniProtKB.::GO:0042059; P:negative regulation of epidermal growth factor receptor signaling pathway; ISS:UniProtKB.::GO:0043407; P:negative regulation of MAP kinase activity; IDA:UniProtKB.::GO:0010642; P:negative regulation of platelet-derived growth factor receptor signaling pathway; IDA:UniProtKB.::GO:0051898; P:negative regulation of protein kinase B signaling cascade; ISS:UniProtKB.::GO:2000272; P:negative regulation of receptor activity; IMP:UniProtKB.::GO:0050860; P:negative regulation of T cell receptor signaling pathway; IDA:UniProtKB.::GO:0048008; P:platelet-derived growth factor receptor signaling pathway; ISS:UniProtKB.::GO:0051894; P:positive regulation of focal adhesion assembly; ISS:UniProtKB.::GO:0010759; P:positive regulation of macrophage chemotaxis; IDA:UniProtKB.::GO:0010572; P:positive regulation of platelet activation; IMP:UniProtKB.::GO:0001570; P:vasculogenesis; IMP:MGI. | 36 | P49446 | 699 | PTPRE_MOUSE Receptor-type tyrosine-protein ph... | 211 | 0.000000000005 | 72.4 | 30 | 44 | GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IDA:UniProtKB. | | | | | | | | | | GO:0042803; F:protein homodimerization activity; IDA:MGI.::GO:0004725; F:protein tyrosine phosphatase activity; IDA:MGI. | | | | | | | | | | GO:0046627; P:negative regulation of insulin receptor signaling pathway; IDA:UniProtKB.::GO:0006468; P:protein phosphorylation; IEA:InterPro.::GO:0033003; P:regulation of mast cell activation; IMP:UniProtKB.::GO:0007185; P:transmembrane receptor protein tyrosine phosphatase signaling pathway; IDA:MGI. | 37 | Q64605 | 1907 | PTPRS_RAT Receptor-type tyrosine-protein phos... | 211 | 0.00000000000003 | 79.7 | 31 | 45 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IDA:RGD.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007155; P:cell adhesion; IEA:UniProtKB-KW. | 38 | B2GV87 | 699 | PTPRE_RAT Receptor-type tyrosine-protein phos... | 211 | 0.000000000006 | 72 | 30 | 44 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; NAS:RGD. | | | | | | | | | | GO:0046627; P:negative regulation of insulin receptor signaling pathway; IDA:UniProtKB.::GO:0006468; P:protein phosphorylation; IEA:InterPro. | 39 | B0V2N1 | 1907 | PTPRS_MOUSE Receptor-type tyrosine-protein ph... | 211 | 0.00000000000006 | 79 | 31 | 45 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0021549; P:cerebellum development; IMP:MGI.::GO:0021987; P:cerebral cortex development; IMP:MGI.::GO:0022038; P:corpus callosum development; IMP:MGI.::GO:0021766; P:hippocampus development; IMP:MGI.::GO:0021510; P:spinal cord development; IMP:MGI. | 40 | P25044 | 335 | PTP1_YEAST Tyrosine-protein phosphatase 1 OS=... | 222 | 0.000000000000007 | 79.3 | 31 | 44 | GO:0005739; C:mitochondrion; IDA:SGD. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct.::GO:0004725; F:protein tyrosine phosphatase activity; IDA:SGD. | | | | | | | | | | GO:0001403; P:invasive growth in response to glucose limitation; IMP:SGD.::GO:0007124; P:pseudohyphal growth; IMP:SGD. | 41 | P35236 | 360 | PTN7_HUMAN Tyrosine-protein phosphatase non-r... | 214 | 0.000000000000007 | 79.7 | 33 | 44 | GO:0005829; C:cytosol; IDA:BHF-UCL.::GO:0009898; C:internal side of plasma membrane; IDA:UniProtKB. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; TAS:ProtInc. | | | | | | | | | | | 42 | O88488 | 2302 | PTPRQ_RAT Phosphotidylinositol phosphatase PT... | 206 | 0.000000000000008 | 82 | 27 | 42 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0045598; P:regulation of fat cell differentiation; ISS:UniProtKB. | 43 | Q64604 | 1898 | PTPRF_RAT Receptor-type tyrosine-protein phos... | 211 | 0.00000000000005 | 79 | 31 | 45 | GO:0005768; C:endosome; IDA:RGD.::GO:0060076; C:excitatory synapse; IDA:RGD.::GO:0030426; C:growth cone; IDA:RGD.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IDA:RGD.::GO:0043025; C:neuronal cell body; IDA:RGD.::GO:0005886; C:plasma membrane; IDA:RGD. | | | | | | | | | | GO:0005158; F:insulin receptor binding; IDA:RGD.::GO:0042301; F:phosphate ion binding; IDA:RGD.::GO:0030971; F:receptor tyrosine kinase binding; IPI:RGD.::GO:0005001; F:transmembrane receptor protein tyrosine phosphatase activity; IDA:RGD. | | | | | | | | | | GO:0007156; P:homophilic cell adhesion; IDA:RGD.::GO:0031345; P:negative regulation of cell projection organization; IMP:RGD.::GO:0008285; P:negative regulation of cell proliferation; IMP:RGD.::GO:0001960; P:negative regulation of cytokine-mediated signaling pathway; IMP:RGD.::GO:0042059; P:negative regulation of epidermal growth factor receptor signaling pathway; IMP:RGD.::GO:0046627; P:negative regulation of insulin receptor signaling pathway; IMP:RGD.::GO:0051387; P:negative regulation of nerve growth factor receptor signaling pathway; IMP:RGD.::GO:0050775; P:positive regulation of dendrite morphogenesis; IMP:RGD.::GO:0043525; P:positive regulation of neuron apoptotic process; IMP:RGD.::GO:0050803; P:regulation of synapse structure and activity; IMP:RGD. | 44 | P10586 | 1907 | PTPRF_HUMAN Receptor-type tyrosine-protein ph... | 211 | 0.0000000000002 | 77 | 31 | 45 | GO:0005887; C:integral to plasma membrane; TAS:ProtInc. | | | | | | | | | | GO:0005001; F:transmembrane receptor protein tyrosine phosphatase activity; TAS:ProtInc. | | | | | | | | | | GO:0007185; P:transmembrane receptor protein tyrosine phosphatase signaling pathway; TAS:ProtInc. | 45 | A2A8L5 | 1898 | PTPRF_MOUSE Receptor-type tyrosine-protein ph... | 211 | 0.00000000000008 | 78.6 | 32 | 45 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | | | | | | | | | | | | 46 | A7MBJ4 | 1898 | PTPRF_BOVIN Receptor-type tyrosine-protein ph... | 213 | 0.0000000000004 | 76.3 | 31 | 45 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; ISS:UniProtKB.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007155; P:cell adhesion; IEA:UniProtKB-KW. | 47 | Q4JDL3 | 420 | PTN20_HUMAN Tyrosine-protein phosphatase non-... | 226 | 0.00000000000001 | 79.7 | 28 | 44 | GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC. | | | | | | | | | | | 48 | P28828 | 1452 | PTPRM_MOUSE Receptor-type tyrosine-protein ph... | 117 | 0.002 | 44.7 | 28 | 44 | GO:0005913; C:cell-cell adherens junction; ISS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0030027; C:lamellipodium; ISS:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; ISS:UniProtKB. | | | | | | | | | | GO:0045296; F:cadherin binding; ISS:UniProtKB.::GO:0005001; F:transmembrane receptor protein tyrosine phosphatase activity; ISS:UniProtKB. | | | | | | | | | | GO:0007156; P:homophilic cell adhesion; ISS:UniProtKB.::GO:0016525; P:negative regulation of angiogenesis; ISS:UniProtKB.::GO:0010596; P:negative regulation of endothelial cell migration; ISS:UniProtKB.::GO:0001937; P:negative regulation of endothelial cell proliferation; ISS:UniProtKB.::GO:0045909; P:positive regulation of vasodilation; IMP:MGI.::GO:0042493; P:response to drug; ISS:UniProtKB.::GO:0010842; P:retina layer formation; ISS:UniProtKB.::GO:0031290; P:retinal ganglion cell axon guidance; ISS:UniProtKB. | 49 | P0C5E4 | 2300 | PTPRQ_MOUSE Phosphotidylinositol phosphatase ... | 206 | 0.00000000000001 | 81.3 | 27 | 42 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0042472; P:inner ear morphogenesis; IMP:MGI.::GO:0045598; P:regulation of fat cell differentiation; ISS:UniProtKB. | 50 | Q05209 | 780 | PTN12_HUMAN Tyrosine-protein phosphatase non-... | 213 | 0.00000000000001 | 80.5 | 25 | 48 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0042995; C:cell projection; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IDA:HPA.::GO:0002102; C:podosome; IEA:UniProtKB-SubCell.::GO:0005625; C:soluble fraction; TAS:ProtInc. | | | | | | | | | | GO:0004726; F:non-membrane spanning protein tyrosine phosphatase activity; TAS:ProtInc.::GO:0017124; F:SH3 domain binding; IPI:UniProtKB. | | | | | | | | | | | 51 | P35831 | 775 | PTN12_MOUSE Tyrosine-protein phosphatase non-... | 213 | 0.00000000000002 | 79.7 | 24 | 46 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0042995; C:cell projection; IEA:UniProtKB-KW.::GO:0005829; C:cytosol; IDA:MGI.::GO:0002102; C:podosome; IDA:UniProtKB. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC. | | | | | | | | | | | 52 | P70289 | 1705 | PTPRV_MOUSE Receptor-type tyrosine-protein ph... | 212 | 0.00000000000003 | 80.1 | 31 | 46 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC. | | | | | | | | | | | 53 | Q03348 | 796 | PTPRA_RAT Receptor-type tyrosine-protein phos... | 218 | 0.000000000006 | 72 | 28 | 45 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IDA:RGD.::GO:0005886; C:plasma membrane; IDA:RGD.::GO:0001950; C:plasma membrane enriched fraction; IDA:RGD. | | | | | | | | | | GO:0032403; F:protein complex binding; IDA:RGD.::GO:0004725; F:protein tyrosine phosphatase activity; IDA:RGD. | | | | | | | | | | GO:0048709; P:oligodendrocyte differentiation; IEP:RGD.::GO:0048714; P:positive regulation of oligodendrocyte differentiation; IMP:RGD.::GO:0006468; P:protein phosphorylation; IEA:InterPro. | 54 | Q9HD43 | 1115 | PTPRH_HUMAN Receptor-type tyrosine-protein ph... | 212 | 0.00000000000005 | 79 | 32 | 47 | GO:0005887; C:integral to plasma membrane; TAS:ProtInc.::GO:0005739; C:mitochondrion; IDA:HPA.::GO:0005634; C:nucleus; IDA:HPA. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct.::GO:0005001; F:transmembrane receptor protein tyrosine phosphatase activity; TAS:ProtInc. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW. | 55 | P08575 | 1304 | PTPRC_HUMAN Receptor-type tyrosine-protein ph... | 236 | 0.000000004 | 63.5 | 24 | 42 | GO:0009897; C:external side of plasma membrane; IDA:MGI.::GO:0005925; C:focal adhesion; ISS:UniProtKB.::GO:0005887; C:integral to plasma membrane; ISS:UniProtKB.::GO:0045121; C:membrane raft; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0005001; F:transmembrane receptor protein tyrosine phosphatase activity; TAS:ProtInc. | | | | | | | | | | GO:0007411; P:axon guidance; TAS:Reactome.::GO:0042100; P:B cell proliferation; ISS:UniProtKB.::GO:0050853; P:B cell receptor signaling pathway; ISS:UniProtKB.::GO:0048539; P:bone marrow development; IMP:UniProtKB.::GO:0051607; P:defense response to virus; ISS:UniProtKB.::GO:0002244; P:hemopoietic progenitor cell differentiation; IMP:UniProtKB.::GO:0002378; P:immunoglobulin biosynthetic process; IMP:UniProtKB.::GO:0006933; P:negative regulation of cell adhesion involved in substrate-bound cell migration; IMP:UniProtKB.::GO:0001960; P:negative regulation of cytokine-mediated signaling pathway; ISS:UniProtKB.::GO:0006469; P:negative regulation of protein kinase activity; IDA:UniProtKB.::GO:0001915; P:negative regulation of T cell mediated cytotoxicity; ISS:UniProtKB.::GO:0050857; P:positive regulation of antigen receptor-mediated signaling pathway; ISS:UniProtKB.::GO:0030890; P:positive regulation of B cell proliferation; IMP:UniProtKB.::GO:2000473; P:positive regulation of hematopoietic stem cell migration; IMP:UniProtKB.::GO:0045860; P:positive regulation of protein kinase activity; NAS:UniProtKB.::GO:2000648; P:positive regulation of stem cell proliferation; IMP:UniProtKB.::GO:0042102; P:positive regulation of T cell proliferation; ISS:UniProtKB.::GO:0033261; P:regulation of S phase; IMP:UniProtKB.::GO:0051209; P:release of sequestered calcium ion into cytosol; ISS:UniProtKB.::GO:0048864; P:stem cell development; IMP:UniProtKB.::GO:0030217; P:T cell differentiation; ISS:UniProtKB.::GO:0050852; P:T cell receptor signaling pathway; IDA:UniProtKB. | 56 | Q9UMZ3 | 2332 | PTPRQ_HUMAN Phosphotidylinositol phosphatase ... | 206 | 0.00000000000006 | 79 | 27 | 41 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0045598; P:regulation of fat cell differentiation; IDA:UniProtKB. | 57 | Q641Z2 | 593 | PTN9_RAT Tyrosine-protein phosphatase non-rec... | 223 | 0.00000000000008 | 77.8 | 28 | 43 | | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; ISS:UniProtKB. | | | | | | | | | | | 58 | Q90687 | 593 | PTN11_CHICK Tyrosine-protein phosphatase non-... | 205 | 0.00000000000008 | 77.8 | 31 | 47 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC. | | | | | | | | | | | 59 | P04157 | 1273 | PTPRC_RAT Receptor-type tyrosine-protein phos... | 216 | 0.000001 | 55.1 | 25 | 41 | GO:0005925; C:focal adhesion; ISS:UniProtKB.::GO:0005887; C:integral to plasma membrane; IDA:UniProtKB.::GO:0009898; C:internal side of plasma membrane; TAS:RGD.::GO:0045121; C:membrane raft; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0019901; F:protein kinase binding; ISS:UniProtKB.::GO:0019887; F:protein kinase regulator activity; TAS:RGD.::GO:0005001; F:transmembrane receptor protein tyrosine phosphatase activity; TAS:RGD. | | | | | | | | | | GO:0042100; P:B cell proliferation; ISS:UniProtKB.::GO:0050853; P:B cell receptor signaling pathway; ISS:UniProtKB.::GO:0051607; P:defense response to virus; ISS:UniProtKB.::GO:0001960; P:negative regulation of cytokine-mediated signaling pathway; ISS:UniProtKB.::GO:0006469; P:negative regulation of protein kinase activity; ISS:UniProtKB.::GO:0001915; P:negative regulation of T cell mediated cytotoxicity; ISS:UniProtKB.::GO:0050857; P:positive regulation of antigen receptor-mediated signaling pathway; ISS:UniProtKB.::GO:0051209; P:release of sequestered calcium ion into cytosol; ISS:UniProtKB.::GO:0010332; P:response to gamma radiation; IDA:RGD.::GO:0050852; P:T cell receptor signaling pathway; ISS:UniProtKB. | 60 | O35239 | 593 | PTN9_MOUSE Tyrosine-protein phosphatase non-r... | 223 | 0.0000000000001 | 77.4 | 30 | 44 | | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; ISS:UniProtKB. | | | | | | | | | | | 61 | Q05909 | 1442 | PTPRG_MOUSE Receptor-type tyrosine-protein ph... | 220 | 0.0000000000001 | 77.8 | 28 | 43 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0042802; F:identical protein binding; ISS:UniProtKB.::GO:0004725; F:protein tyrosine phosphatase activity; ISS:UniProtKB. | | | | | | | | | | |