Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Blastomyces dermatitidis ER-3
Locus:
BDCG_00870
Length:
552
Number of sequences:
9522
Description:
protein-tyrosine phosphatase 2
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
31P28827    1452   PTPRM_HUMAN Receptor-type tyrosine-protein ph...1170.002     44.7     28     44GO:0005913; C:cell-cell adherens junction; IDA:UniProtKB.::GO:0005887; C:integral to plasma membrane; NAS:UniProtKB.::GO:0030027; C:lamellipodium; IDA:MGI.::GO:0048471; C:perinuclear region of cytoplasm; IDA:UniProtKB.
GO:0045296; F:cadherin binding; IDA:UniProtKB.::GO:0005001; F:transmembrane receptor protein tyrosine phosphatase activity; IDA:UniProtKB.
GO:0007156; P:homophilic cell adhesion; IDA:UniProtKB.::GO:0016525; P:negative regulation of angiogenesis; IMP:UniProtKB.::GO:0010596; P:negative regulation of endothelial cell migration; IMP:UniProtKB.::GO:0001937; P:negative regulation of endothelial cell proliferation; IMP:UniProtKB.::GO:0042493; P:response to drug; IDA:UniProtKB.::GO:0010842; P:retina layer formation; IMP:UniProtKB.::GO:0031290; P:retinal ganglion cell axon guidance; IDA:UniProtKB.
32P32587    303   PYP3_SCHPO Tyrosine-protein phosphatase 3 OS=...2200.000000000000004     79.7     27     44GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
GO:0004725; F:protein tyrosine phosphatase activity; IDA:PomBase.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0007346; P:regulation of mitotic cell cycle; IMP:PomBase.::GO:0007165; P:signal transduction; IC:PomBase.
33A4IFW2    1909   PTPRF_DANRE Receptor-type tyrosine-protein ph...2150.0000000000003     77     30     46GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.
GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
34P18052    829   PTPRA_MOUSE Receptor-type tyrosine-protein ph...2180.000000000006     72.4     28     45GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
GO:0008286; P:insulin receptor signaling pathway; IMP:MGI.::GO:0006468; P:protein phosphorylation; IDA:MGI.
35Q64455    1238   PTPRJ_MOUSE Receptor-type tyrosine-protein ph...2150.000000000000005     82.4     29     47GO:0005911; C:cell-cell junction; ISS:UniProtKB.::GO:0001772; C:immunological synapse; IDA:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0032587; C:ruffle membrane; IDA:UniProtKB.
GO:0004725; F:protein tyrosine phosphatase activity; IMP:UniProtKB.
GO:0007596; P:blood coagulation; IMP:UniProtKB.::GO:0007507; P:heart development; IMP:MGI.::GO:0030336; P:negative regulation of cell migration; IDA:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; IMP:UniProtKB.::GO:0042059; P:negative regulation of epidermal growth factor receptor signaling pathway; ISS:UniProtKB.::GO:0043407; P:negative regulation of MAP kinase activity; IDA:UniProtKB.::GO:0010642; P:negative regulation of platelet-derived growth factor receptor signaling pathway; IDA:UniProtKB.::GO:0051898; P:negative regulation of protein kinase B signaling cascade; ISS:UniProtKB.::GO:2000272; P:negative regulation of receptor activity; IMP:UniProtKB.::GO:0050860; P:negative regulation of T cell receptor signaling pathway; IDA:UniProtKB.::GO:0048008; P:platelet-derived growth factor receptor signaling pathway; ISS:UniProtKB.::GO:0051894; P:positive regulation of focal adhesion assembly; ISS:UniProtKB.::GO:0010759; P:positive regulation of macrophage chemotaxis; IDA:UniProtKB.::GO:0010572; P:positive regulation of platelet activation; IMP:UniProtKB.::GO:0001570; P:vasculogenesis; IMP:MGI.
36P49446    699   PTPRE_MOUSE Receptor-type tyrosine-protein ph...2110.000000000005     72.4     30     44GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IDA:UniProtKB.
GO:0042803; F:protein homodimerization activity; IDA:MGI.::GO:0004725; F:protein tyrosine phosphatase activity; IDA:MGI.
GO:0046627; P:negative regulation of insulin receptor signaling pathway; IDA:UniProtKB.::GO:0006468; P:protein phosphorylation; IEA:InterPro.::GO:0033003; P:regulation of mast cell activation; IMP:UniProtKB.::GO:0007185; P:transmembrane receptor protein tyrosine phosphatase signaling pathway; IDA:MGI.
37Q64605    1907   PTPRS_RAT Receptor-type tyrosine-protein phos...2110.00000000000003     79.7     31     45GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0004725; F:protein tyrosine phosphatase activity; IDA:RGD.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.
GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
38B2GV87    699   PTPRE_RAT Receptor-type tyrosine-protein phos...2110.000000000006     72     30     44GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0004725; F:protein tyrosine phosphatase activity; NAS:RGD.
GO:0046627; P:negative regulation of insulin receptor signaling pathway; IDA:UniProtKB.::GO:0006468; P:protein phosphorylation; IEA:InterPro.
39B0V2N1    1907   PTPRS_MOUSE Receptor-type tyrosine-protein ph...2110.00000000000006     79     31     45GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.
GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0021549; P:cerebellum development; IMP:MGI.::GO:0021987; P:cerebral cortex development; IMP:MGI.::GO:0022038; P:corpus callosum development; IMP:MGI.::GO:0021766; P:hippocampus development; IMP:MGI.::GO:0021510; P:spinal cord development; IMP:MGI.
40P25044    335   PTP1_YEAST Tyrosine-protein phosphatase 1 OS=...2220.000000000000007     79.3     31     44GO:0005739; C:mitochondrion; IDA:SGD.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0004725; F:protein tyrosine phosphatase activity; IDA:SGD.
GO:0001403; P:invasive growth in response to glucose limitation; IMP:SGD.::GO:0007124; P:pseudohyphal growth; IMP:SGD.
41P35236    360   PTN7_HUMAN Tyrosine-protein phosphatase non-r...2140.000000000000007     79.7     33     44GO:0005829; C:cytosol; IDA:BHF-UCL.::GO:0009898; C:internal side of plasma membrane; IDA:UniProtKB.
GO:0004725; F:protein tyrosine phosphatase activity; TAS:ProtInc.
42O88488    2302   PTPRQ_RAT Phosphotidylinositol phosphatase PT...2060.000000000000008     82     27     42GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.
GO:0045598; P:regulation of fat cell differentiation; ISS:UniProtKB.
43Q64604    1898   PTPRF_RAT Receptor-type tyrosine-protein phos...2110.00000000000005     79     31     45GO:0005768; C:endosome; IDA:RGD.::GO:0060076; C:excitatory synapse; IDA:RGD.::GO:0030426; C:growth cone; IDA:RGD.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IDA:RGD.::GO:0043025; C:neuronal cell body; IDA:RGD.::GO:0005886; C:plasma membrane; IDA:RGD.
GO:0005158; F:insulin receptor binding; IDA:RGD.::GO:0042301; F:phosphate ion binding; IDA:RGD.::GO:0030971; F:receptor tyrosine kinase binding; IPI:RGD.::GO:0005001; F:transmembrane receptor protein tyrosine phosphatase activity; IDA:RGD.
GO:0007156; P:homophilic cell adhesion; IDA:RGD.::GO:0031345; P:negative regulation of cell projection organization; IMP:RGD.::GO:0008285; P:negative regulation of cell proliferation; IMP:RGD.::GO:0001960; P:negative regulation of cytokine-mediated signaling pathway; IMP:RGD.::GO:0042059; P:negative regulation of epidermal growth factor receptor signaling pathway; IMP:RGD.::GO:0046627; P:negative regulation of insulin receptor signaling pathway; IMP:RGD.::GO:0051387; P:negative regulation of nerve growth factor receptor signaling pathway; IMP:RGD.::GO:0050775; P:positive regulation of dendrite morphogenesis; IMP:RGD.::GO:0043525; P:positive regulation of neuron apoptotic process; IMP:RGD.::GO:0050803; P:regulation of synapse structure and activity; IMP:RGD.
44P10586    1907   PTPRF_HUMAN Receptor-type tyrosine-protein ph...2110.0000000000002     77     31     45GO:0005887; C:integral to plasma membrane; TAS:ProtInc.
GO:0005001; F:transmembrane receptor protein tyrosine phosphatase activity; TAS:ProtInc.
GO:0007185; P:transmembrane receptor protein tyrosine phosphatase signaling pathway; TAS:ProtInc.
45A2A8L5    1898   PTPRF_MOUSE Receptor-type tyrosine-protein ph...2110.00000000000008     78.6     32     45GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
46A7MBJ4    1898   PTPRF_BOVIN Receptor-type tyrosine-protein ph...2130.0000000000004     76.3     31     45GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0004725; F:protein tyrosine phosphatase activity; ISS:UniProtKB.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.
GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
47Q4JDL3    420   PTN20_HUMAN Tyrosine-protein phosphatase non-...2260.00000000000001     79.7     28     44GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
48P28828    1452   PTPRM_MOUSE Receptor-type tyrosine-protein ph...1170.002     44.7     28     44GO:0005913; C:cell-cell adherens junction; ISS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0030027; C:lamellipodium; ISS:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; ISS:UniProtKB.
GO:0045296; F:cadherin binding; ISS:UniProtKB.::GO:0005001; F:transmembrane receptor protein tyrosine phosphatase activity; ISS:UniProtKB.
GO:0007156; P:homophilic cell adhesion; ISS:UniProtKB.::GO:0016525; P:negative regulation of angiogenesis; ISS:UniProtKB.::GO:0010596; P:negative regulation of endothelial cell migration; ISS:UniProtKB.::GO:0001937; P:negative regulation of endothelial cell proliferation; ISS:UniProtKB.::GO:0045909; P:positive regulation of vasodilation; IMP:MGI.::GO:0042493; P:response to drug; ISS:UniProtKB.::GO:0010842; P:retina layer formation; ISS:UniProtKB.::GO:0031290; P:retinal ganglion cell axon guidance; ISS:UniProtKB.
49P0C5E4    2300   PTPRQ_MOUSE Phosphotidylinositol phosphatase ...2060.00000000000001     81.3     27     42GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.
GO:0042472; P:inner ear morphogenesis; IMP:MGI.::GO:0045598; P:regulation of fat cell differentiation; ISS:UniProtKB.
50Q05209    780   PTN12_HUMAN Tyrosine-protein phosphatase non-...2130.00000000000001     80.5     25     48GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0042995; C:cell projection; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IDA:HPA.::GO:0002102; C:podosome; IEA:UniProtKB-SubCell.::GO:0005625; C:soluble fraction; TAS:ProtInc.
GO:0004726; F:non-membrane spanning protein tyrosine phosphatase activity; TAS:ProtInc.::GO:0017124; F:SH3 domain binding; IPI:UniProtKB.
51P35831    775   PTN12_MOUSE Tyrosine-protein phosphatase non-...2130.00000000000002     79.7     24     46GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0042995; C:cell projection; IEA:UniProtKB-KW.::GO:0005829; C:cytosol; IDA:MGI.::GO:0002102; C:podosome; IDA:UniProtKB.
GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
52P70289    1705   PTPRV_MOUSE Receptor-type tyrosine-protein ph...2120.00000000000003     80.1     31     46GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
53Q03348    796   PTPRA_RAT Receptor-type tyrosine-protein phos...2180.000000000006     72     28     45GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IDA:RGD.::GO:0005886; C:plasma membrane; IDA:RGD.::GO:0001950; C:plasma membrane enriched fraction; IDA:RGD.
GO:0032403; F:protein complex binding; IDA:RGD.::GO:0004725; F:protein tyrosine phosphatase activity; IDA:RGD.
GO:0048709; P:oligodendrocyte differentiation; IEP:RGD.::GO:0048714; P:positive regulation of oligodendrocyte differentiation; IMP:RGD.::GO:0006468; P:protein phosphorylation; IEA:InterPro.
54Q9HD43    1115   PTPRH_HUMAN Receptor-type tyrosine-protein ph...2120.00000000000005     79     32     47GO:0005887; C:integral to plasma membrane; TAS:ProtInc.::GO:0005739; C:mitochondrion; IDA:HPA.::GO:0005634; C:nucleus; IDA:HPA.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0005001; F:transmembrane receptor protein tyrosine phosphatase activity; TAS:ProtInc.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
55P08575    1304   PTPRC_HUMAN Receptor-type tyrosine-protein ph...2360.000000004     63.5     24     42GO:0009897; C:external side of plasma membrane; IDA:MGI.::GO:0005925; C:focal adhesion; ISS:UniProtKB.::GO:0005887; C:integral to plasma membrane; ISS:UniProtKB.::GO:0045121; C:membrane raft; IEA:UniProtKB-SubCell.
GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0005001; F:transmembrane receptor protein tyrosine phosphatase activity; TAS:ProtInc.
GO:0007411; P:axon guidance; TAS:Reactome.::GO:0042100; P:B cell proliferation; ISS:UniProtKB.::GO:0050853; P:B cell receptor signaling pathway; ISS:UniProtKB.::GO:0048539; P:bone marrow development; IMP:UniProtKB.::GO:0051607; P:defense response to virus; ISS:UniProtKB.::GO:0002244; P:hemopoietic progenitor cell differentiation; IMP:UniProtKB.::GO:0002378; P:immunoglobulin biosynthetic process; IMP:UniProtKB.::GO:0006933; P:negative regulation of cell adhesion involved in substrate-bound cell migration; IMP:UniProtKB.::GO:0001960; P:negative regulation of cytokine-mediated signaling pathway; ISS:UniProtKB.::GO:0006469; P:negative regulation of protein kinase activity; IDA:UniProtKB.::GO:0001915; P:negative regulation of T cell mediated cytotoxicity; ISS:UniProtKB.::GO:0050857; P:positive regulation of antigen receptor-mediated signaling pathway; ISS:UniProtKB.::GO:0030890; P:positive regulation of B cell proliferation; IMP:UniProtKB.::GO:2000473; P:positive regulation of hematopoietic stem cell migration; IMP:UniProtKB.::GO:0045860; P:positive regulation of protein kinase activity; NAS:UniProtKB.::GO:2000648; P:positive regulation of stem cell proliferation; IMP:UniProtKB.::GO:0042102; P:positive regulation of T cell proliferation; ISS:UniProtKB.::GO:0033261; P:regulation of S phase; IMP:UniProtKB.::GO:0051209; P:release of sequestered calcium ion into cytosol; ISS:UniProtKB.::GO:0048864; P:stem cell development; IMP:UniProtKB.::GO:0030217; P:T cell differentiation; ISS:UniProtKB.::GO:0050852; P:T cell receptor signaling pathway; IDA:UniProtKB.
56Q9UMZ3    2332   PTPRQ_HUMAN Phosphotidylinositol phosphatase ...2060.00000000000006     79     27     41GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.
GO:0045598; P:regulation of fat cell differentiation; IDA:UniProtKB.
57Q641Z2    593   PTN9_RAT Tyrosine-protein phosphatase non-rec...2230.00000000000008     77.8     28     43
GO:0004725; F:protein tyrosine phosphatase activity; ISS:UniProtKB.
58Q90687    593   PTN11_CHICK Tyrosine-protein phosphatase non-...2050.00000000000008     77.8     31     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
59P04157    1273   PTPRC_RAT Receptor-type tyrosine-protein phos...2160.000001     55.1     25     41GO:0005925; C:focal adhesion; ISS:UniProtKB.::GO:0005887; C:integral to plasma membrane; IDA:UniProtKB.::GO:0009898; C:internal side of plasma membrane; TAS:RGD.::GO:0045121; C:membrane raft; IEA:UniProtKB-SubCell.
GO:0019901; F:protein kinase binding; ISS:UniProtKB.::GO:0019887; F:protein kinase regulator activity; TAS:RGD.::GO:0005001; F:transmembrane receptor protein tyrosine phosphatase activity; TAS:RGD.
GO:0042100; P:B cell proliferation; ISS:UniProtKB.::GO:0050853; P:B cell receptor signaling pathway; ISS:UniProtKB.::GO:0051607; P:defense response to virus; ISS:UniProtKB.::GO:0001960; P:negative regulation of cytokine-mediated signaling pathway; ISS:UniProtKB.::GO:0006469; P:negative regulation of protein kinase activity; ISS:UniProtKB.::GO:0001915; P:negative regulation of T cell mediated cytotoxicity; ISS:UniProtKB.::GO:0050857; P:positive regulation of antigen receptor-mediated signaling pathway; ISS:UniProtKB.::GO:0051209; P:release of sequestered calcium ion into cytosol; ISS:UniProtKB.::GO:0010332; P:response to gamma radiation; IDA:RGD.::GO:0050852; P:T cell receptor signaling pathway; ISS:UniProtKB.
60O35239    593   PTN9_MOUSE Tyrosine-protein phosphatase non-r...2230.0000000000001     77.4     30     44
GO:0004725; F:protein tyrosine phosphatase activity; ISS:UniProtKB.
61Q05909    1442   PTPRG_MOUSE Receptor-type tyrosine-protein ph...2200.0000000000001     77.8     28     43GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0042802; F:identical protein binding; ISS:UniProtKB.::GO:0004725; F:protein tyrosine phosphatase activity; ISS:UniProtKB.
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