| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
31 | A5PMU4 | 1280 | ANS1B_DANRE Ankyrin repeat and sterile alpha ... | 91 | 2.4 | 32.7 | 26 | 42 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 32 | Q03017 | 500 | CACT_DROME NF-kappa-B inhibitor cactus OS=Dro... | 87 | 2.5 | 32.3 | 26 | 43 | GO:0005737; C:cytoplasm; IDA:FlyBase.::GO:0031594; C:neuromuscular junction; IDA:FlyBase. | | | | | | | | | | GO:0008134; F:transcription factor binding; TAS:FlyBase. | | | | | | | | | | GO:0019732; P:antifungal humoral response; IMP:FlyBase.::GO:0046843; P:dorsal appendage formation; IMP:FlyBase.::GO:0009950; P:dorsal/ventral axis specification; IMP:FlyBase.::GO:0030097; P:hemopoiesis; TAS:FlyBase.::GO:0045087; P:innate immune response; NAS:FlyBase.::GO:0007399; P:nervous system development; IMP:FlyBase.::GO:0006911; P:phagocytosis, engulfment; IMP:FlyBase.::GO:0006967; P:positive regulation of antifungal peptide biosynthetic process; IMP:FlyBase.::GO:0006974; P:response to DNA damage stimulus; IMP:FlyBase.::GO:0008063; P:Toll signaling pathway; TAS:FlyBase. | 33 | Q92625 | 1134 | ANS1A_HUMAN Ankyrin repeat and SAM domain-con... | 96 | 2.6 | 32.3 | 27 | 39 | GO:0005737; C:cytoplasm; IDA:HPA.::GO:0043005; C:neuron projection; ISS:UniProtKB.::GO:0005634; C:nucleus; IDA:HPA. | | | | | | | | | | | | | | | | | | | | GO:0048013; P:ephrin receptor signaling pathway; ISS:UniProtKB.::GO:0016322; P:neuron remodeling; ISS:UniProtKB.::GO:0006929; P:substrate-dependent cell migration; ISS:UniProtKB. | 34 | Q14DN9 | 465 | AKD1B_MOUSE Ankyrin repeat and death domain-c... | 47 | 2.7 | 32.3 | 28 | 57 | | | | | | | | | | | | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 35 | Q8WXI3 | 467 | ASB10_HUMAN Ankyrin repeat and SOCS box prote... | 88 | 3 | 32 | 25 | 41 | | | | | | | | | | | | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 36 | Q3SX45 | 633 | ASB2_BOVIN Ankyrin repeat and SOCS box protei... | 129 | 3.1 | 32 | 24 | 43 | | | | | | | | | | | | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 37 | Q9VUX2 | 1226 | MIB_DROME E3 ubiquitin-protein ligase mind-bo... | 122 | 3.4 | 32 | 22 | 44 | GO:0045179; C:apical cortex; IDA:UniProtKB. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; NAS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006897; P:endocytosis; IMP:UniProtKB.::GO:0046331; P:lateral inhibition; IMP:FlyBase.::GO:0007219; P:Notch signaling pathway; IMP:FlyBase.::GO:0045747; P:positive regulation of Notch signaling pathway; IMP:UniProtKB.::GO:0008104; P:protein localization; IMP:UniProtKB.::GO:0007423; P:sensory organ development; IMP:FlyBase. | 38 | Q2T1B8 | 208 | RL25_BURTA 50S ribosomal protein L25 OS=CIP 1... | 114 | 3.6 | 31.6 | 22 | 43 | GO:0005840; C:ribosome; IEA:UniProtKB-KW. | | | | | | | | | | GO:0008097; F:5S rRNA binding; IEA:InterPro.::GO:0003735; F:structural constituent of ribosome; IEA:InterPro. | | | | | | | | | | GO:0006412; P:translation; IEA:InterPro. | 39 | P20749 | 454 | BCL3_HUMAN B-cell lymphoma 3 protein OS=Homo ... | 89 | 3.6 | 32 | 26 | 44 | GO:0032996; C:Bcl3-Bcl10 complex; IDA:UniProtKB.::GO:0033257; C:Bcl3/NF-kappaB2 complex; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0030674; F:protein binding, bridging; TAS:UniProtKB.::GO:0008134; F:transcription factor binding; IPI:UniProtKB. | | | | | | | | | | GO:0042771; P:DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis; IMP:MGI.::GO:0007249; P:I-kappaB kinase/NF-kappaB cascade; IDA:UniProtKB.::GO:0051457; P:maintenance of protein location in nucleus; NAS:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; IDA:UniProtKB.::GO:0045415; P:negative regulation of interleukin-8 biosynthetic process; IMP:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0045727; P:positive regulation of translation; IMP:UniProtKB.::GO:0000060; P:protein import into nucleus, translocation; IMP:UniProtKB.::GO:0051101; P:regulation of DNA binding; IEP:UniProtKB.::GO:0042345; P:regulation of NF-kappaB import into nucleus; IEP:UniProtKB.::GO:0010225; P:response to UV-C; IDA:UniProtKB.::GO:0009615; P:response to virus; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IDA:UniProtKB. | 40 | Q96AX9 | 1013 | MIB2_HUMAN E3 ubiquitin-protein ligase MIB2 O... | 83 | 8.7 | 30.8 | 27 | 46 | GO:0005768; C:endosome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0004871; F:signal transducer activity; IMP:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007219; P:Notch signaling pathway; IEA:UniProtKB-KW.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; IMP:UniProtKB. | 41 | Q92380 | 923 | REC11_SCHPO Meiotic recombination protein rec... | 93 | 5.2 | 31.6 | 26 | 47 | GO:0030893; C:meiotic cohesin complex; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase. | | | | | | | | | | GO:0005488; F:binding; IEA:InterPro. | | | | | | | | | | GO:0045143; P:homologous chromosome segregation; TAS:PomBase.::GO:0042138; P:meiotic DNA double-strand break formation; IMP:PomBase.::GO:0051177; P:meiotic sister chromatid cohesion; IDA:PomBase.::GO:0007131; P:reciprocal meiotic recombination; IMP:PomBase. | 42 | Q9VFD5 | 664 | FEM1A_DROME Protein fem-1 homolog CG6966 OS=D... | 62 | 5.3 | 31.6 | 29 | 45 | | | | | | | | | | | GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB. | | | | | | | | | | GO:0051438; P:regulation of ubiquitin-protein ligase activity; ISS:UniProtKB. | 43 | Q12955 | 4377 | ANK3_HUMAN Ankyrin-3 OS=Homo sapiens (Human).... | 110 | 5.4 | 31.6 | 25 | 41 | GO:0016323; C:basolateral plasma membrane; IDA:UniProtKB.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0045184; P:establishment of protein localization; IMP:UniProtKB.::GO:0007165; P:signal transduction; IEA:InterPro. | 44 | Q9EQG6 | 1762 | KDIS_RAT Kinase D-interacting substrate of 22... | 180 | 5.6 | 31.6 | 23 | 37 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0019901; F:protein kinase binding; IDA:RGD.::GO:0019887; F:protein kinase regulator activity; IDA:RGD. | | | | | | | | | | | 45 | Q9C0D5 | 1861 | TANC1_HUMAN Protein TANC1 OS=Homo sapiens (Hu... | 52 | 5.6 | 31.6 | 29 | 56 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.::GO:0014069; C:postsynaptic density; IEA:UniProtKB-SubCell.::GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005488; F:binding; IEA:InterPro. | | | | | | | | | | | 46 | Q5RF15 | 618 | TNI3K_PONAB Serine/threonine-protein kinase T... | 130 | 5.6 | 31.2 | 25 | 40 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 47 | P31695 | 1964 | NOTC4_MOUSE Neurogenic locus notch homolog pr... | 47 | 6.7 | 31.2 | 34 | 51 | GO:0009986; C:cell surface; ISS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0009790; P:embryo development; IMP:UniProtKB.::GO:0045602; P:negative regulation of endothelial cell differentiation; IMP:UniProtKB.::GO:0007219; P:Notch signaling pathway; TAS:UniProtKB.::GO:0001569; P:patterning of blood vessels; IMP:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 48 | Q99466 | 2003 | NOTC4_HUMAN Neurogenic locus notch homolog pr... | 47 | 6.7 | 31.2 | 34 | 51 | GO:0009986; C:cell surface; IDA:UniProtKB.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0005576; C:extracellular region; TAS:Reactome.::GO:0000139; C:Golgi membrane; TAS:Reactome.::GO:0005887; C:integral to plasma membrane; TAS:UniProtKB.::GO:0005654; C:nucleoplasm; TAS:Reactome. | | | | | | | | | | GO:0005509; F:calcium ion binding; TAS:UniProtKB.::GO:0046982; F:protein heterodimerization activity; TAS:UniProtKB.::GO:0004872; F:receptor activity; TAS:UniProtKB. | | | | | | | | | | GO:0001709; P:cell fate determination; TAS:UniProtKB.::GO:0009790; P:embryo development; ISS:UniProtKB.::GO:0030097; P:hemopoiesis; TAS:UniProtKB.::GO:0030879; P:mammary gland development; IDA:UniProtKB.::GO:0045602; P:negative regulation of endothelial cell differentiation; ISS:UniProtKB.::GO:0007220; P:Notch receptor processing; TAS:Reactome.::GO:0007219; P:Notch signaling pathway; TAS:Reactome.::GO:0001569; P:patterning of blood vessels; ISS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; TAS:UniProtKB.::GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome. | 49 | Q5DU14 | 1919 | MYO16_MOUSE Unconventional myosin-XVI OS=Mus ... | 72 | 7 | 31.2 | 28 | 46 | GO:0016459; C:myosin complex; IEA:UniProtKB-KW.::GO:0005654; C:nucleoplasm; ISS:HGNC.::GO:0048471; C:perinuclear region of cytoplasm; ISS:HGNC.::GO:0005886; C:plasma membrane; ISS:HGNC. | | | | | | | | | | GO:0051015; F:actin filament binding; ISS:HGNC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003774; F:motor activity; IEA:InterPro. | | | | | | | | | | GO:0021549; P:cerebellum development; ISS:HGNC.::GO:0008285; P:negative regulation of cell proliferation; ISS:HGNC.::GO:0045749; P:negative regulation of S phase of mitotic cell cycle; ISS:HGNC. | 50 | Q9ULH0 | 1771 | KDIS_HUMAN Kinase D-interacting substrate of ... | 180 | 7.1 | 31.2 | 23 | 37 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | | | | | | | | | | | GO:0000186; P:activation of MAPKK activity; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome. | 51 | Q9ERC1 | 1912 | MYO16_RAT Unconventional myosin-XVI OS=Rattus... | 70 | 8 | 30.8 | 29 | 46 | GO:0005829; C:cytosol; IDA:RGD.::GO:0005626; C:insoluble fraction; IDA:HGNC.::GO:0005624; C:membrane fraction; IDA:RGD.::GO:0016459; C:myosin complex; IDA:RGD.::GO:0005654; C:nucleoplasm; IDA:HGNC.::GO:0048471; C:perinuclear region of cytoplasm; IDA:HGNC.::GO:0005886; C:plasma membrane; IDA:HGNC.::GO:0005625; C:soluble fraction; IDA:HGNC. | | | | | | | | | | GO:0003779; F:actin binding; IDA:RGD.::GO:0051015; F:actin filament binding; IDA:HGNC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003774; F:motor activity; IEA:InterPro.::GO:0019903; F:protein phosphatase binding; IPI:UniProtKB. | | | | | | | | | | GO:0021549; P:cerebellum development; IEP:HGNC.::GO:0008285; P:negative regulation of cell proliferation; IDA:HGNC.::GO:0045749; P:negative regulation of S phase of mitotic cell cycle; IDA:HGNC. | 52 | Q59H18 | 835 | TNI3K_HUMAN Serine/threonine-protein kinase T... | 130 | 8.1 | 30.8 | 25 | 40 | GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0031013; F:troponin I binding; IPI:UniProtKB. | | | | | | | | | | | 53 | Q7Z020 | 1296 | TRPA1_DROME Transient receptor potential cati... | 138 | 9.7 | 30.8 | 25 | 38 | GO:0016021; C:integral to membrane; IC:UniProtKB. | | | | | | | | | | GO:0005261; F:cation channel activity; IDA:UniProtKB. | | | | | | | | | | GO:0034605; P:cellular response to heat; IDA:FlyBase.::GO:0042745; P:circadian sleep/wake cycle; IMP:FlyBase.::GO:0001580; P:detection of chemical stimulus involved in sensory perception of bitter taste; IMP:FlyBase.::GO:0007613; P:memory; IMP:FlyBase.::GO:0043052; P:thermotaxis; IDA:FlyBase. | 54 | Q6UB98 | 2062 | ANR12_HUMAN Ankyrin repeat domain-containing ... | 89 | 9.9 | 30.8 | 33 | 42 | GO:0005737; C:cytoplasm; IDA:HPA.::GO:0005634; C:nucleus; IDA:HPA. | | | | | | | | | | | | | | | | | | | | |
