rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
181 | Q5ZMC3 | 476 | WSDU1_CHICK WD repeat, SAM and U-box domain-c... | 145 | 0.16 | 40 | 28 | 41 | GO:0000151; C:ubiquitin ligase complex; IEA:InterPro. | | | | | | | | | | GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro. | | | | | | | | | | | 182 | A1CF18 | 435 | LIS12_ASPCL Nuclear distribution protein nudF... | 367 | 0.00002 | 52.4 | 22 | 38 | GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW. | 183 | Q9VZF4 | 1326 | FBXW7_DROME F-box/WD repeat-containing protei... | 273 | 0.004 | 45.4 | 23 | 39 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0019005; C:SCF ubiquitin ligase complex; NAS:FlyBase. | | | | | | | | | | GO:0030332; F:cyclin binding; TAS:FlyBase. | | | | | | | | | | GO:0007411; P:axon guidance; IMP:FlyBase.::GO:0008054; P:cyclin catabolic process; TAS:FlyBase.::GO:0042023; P:DNA endoreduplication; IMP:FlyBase.::GO:0060253; P:negative regulation of glial cell proliferation; IGI:FlyBase.::GO:0045926; P:negative regulation of growth; IMP:FlyBase.::GO:0007096; P:regulation of exit from mitosis; TAS:FlyBase.::GO:0007088; P:regulation of mitosis; IMP:FlyBase.::GO:0030162; P:regulation of proteolysis; TAS:FlyBase. | 184 | O60907 | 577 | TBL1X_HUMAN F-box-like/WD repeat-containing p... | 157 | 0.006 | 44.7 | 27 | 45 | GO:0005876; C:spindle microtubule; IDA:UniProtKB.::GO:0017053; C:transcriptional repressor complex; IDA:UniProtKB. | | | | | | | | | | GO:0008013; F:beta-catenin binding; IPI:UniProtKB.::GO:0042393; F:histone binding; IDA:UniProtKB.::GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.::GO:0019904; F:protein domain specific binding; IPI:UniProtKB.::GO:0003714; F:transcription corepressor activity; IDA:UniProtKB.::GO:0008134; F:transcription factor binding; IPI:UniProtKB.::GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB. | | | | | | | | | | GO:0060070; P:canonical Wnt receptor signaling pathway; IMP:UniProtKB.::GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0007219; P:Notch signaling pathway; TAS:Reactome.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0007605; P:sensory perception of sound; IMP:UniProtKB.::GO:0044281; P:small molecule metabolic process; TAS:Reactome.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 185 | Q8C4J7 | 801 | TBL3_MOUSE Transducin beta-like protein 3 OS=... | 249 | 0.038 | 42.4 | 24 | 41 | GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.::GO:0032040; C:small-subunit processome; IEA:InterPro. | | | | | | | | | | | | | | | | | | | | GO:0006364; P:rRNA processing; IEA:InterPro. | 186 | B3MET8 | 667 | WDR48_DROAN WD repeat-containing protein 48 h... | 81 | 0.53 | 38.5 | 28 | 56 | | | | | | | | | | | | | | | | | | | | | | 187 | B4MFM2 | 667 | WDR48_DROVI WD repeat-containing protein 48 h... | 81 | 0.6 | 38.1 | 28 | 56 | | | | | | | | | | | | | | | | | | | | | | 188 | P07834 | 779 | CDC4_YEAST Cell division control protein 4 OS... | 65 | 0.3 | 39.3 | 35 | 51 | GO:0016363; C:nuclear matrix; IDA:SGD.::GO:0043224; C:nuclear SCF ubiquitin ligase complex; IDA:SGD. | | | | | | | | | | GO:0043130; F:ubiquitin binding; IDA:SGD. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0000082; P:G1/S transition of mitotic cell cycle; IMP:SGD.::GO:0000086; P:G2/M transition of mitotic cell cycle; IGI:SGD.::GO:0007126; P:meiosis; IMP:SGD.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IDA:SGD.::GO:0031146; P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; IDA:SGD.::GO:0030435; P:sporulation resulting in formation of a cellular spore; IEA:UniProtKB-KW. | 189 | Q10282 | 305 | GBB_SCHPO Guanine nucleotide-binding protein ... | 154 | 1.8 | 36.2 | 21 | 43 | GO:0005829; C:cytosol; IDA:PomBase.::GO:0005834; C:heterotrimeric G-protein complex; TAS:PomBase.::GO:0005634; C:nucleus; IDA:PomBase. | | | | | | | | | | GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0010619; P:activation of adenylate cyclase activity by glucose-triggered G-protein signaling pathway; TAS:PomBase.::GO:0031138; P:negative regulation of conjugation with cellular fusion; TAS:PomBase.::GO:0045014; P:negative regulation of transcription by glucose; IMP:PomBase.::GO:0030435; P:sporulation resulting in formation of a cellular spore; IEA:UniProtKB-KW. | 190 | Q969H0 | 707 | FBXW7_HUMAN F-box/WD repeat-containing protei... | 260 | 0.0000000008 | 67.4 | 25 | 43 | GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0043234; C:protein complex; IDA:UniProtKB.::GO:0019005; C:SCF ubiquitin ligase complex; IDA:UniProtKB. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0034644; P:cellular response to UV; IDA:UniProtKB.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0055088; P:lipid homeostasis; ISS:BHF-UCL.::GO:0032876; P:negative regulation of DNA endoreduplication; IMP:BHF-UCL.::GO:2000346; P:negative regulation of hepatocyte proliferation; ISS:BHF-UCL.::GO:0045746; P:negative regulation of Notch signaling pathway; ISS:BHF-UCL.::GO:2000639; P:negative regulation of SREBP-mediated signaling pathway; ISS:BHF-UCL.::GO:0010868; P:negative regulation of triglyceride biosynthetic process; ISS:BHF-UCL.::GO:0007219; P:Notch signaling pathway; TAS:Reactome.::GO:0045741; P:positive regulation of epidermal growth factor-activated receptor activity; IDA:BHF-UCL.::GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; IMP:BHF-UCL.::GO:2000060; P:positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IDA:BHF-UCL.::GO:0050821; P:protein stabilization; IDA:BHF-UCL.::GO:0016567; P:protein ubiquitination; IDA:UniProtKB.::GO:0010883; P:regulation of lipid storage; ISS:BHF-UCL.::GO:0032880; P:regulation of protein localization; ISS:BHF-UCL.::GO:0006974; P:response to DNA damage stimulus; IDA:UniProtKB.::GO:0031146; P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; IDA:UniProtKB.::GO:0007062; P:sister chromatid cohesion; IMP:BHF-UCL.::GO:0001944; P:vasculature development; TAS:BHF-UCL. | 191 | Q9BQ87 | 522 | TBL1Y_HUMAN F-box-like/WD repeat-containing p... | 102 | 0.012 | 43.9 | 28 | 46 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 192 | A7EKM8 | 458 | LIS1_SCLS1 Nuclear distribution protein PAC1 ... | 276 | 0.07 | 41.2 | 22 | 43 | GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW. | 193 | Q4R8H1 | 569 | TBL1X_MACFA F-box-like/WD repeat-containing p... | 157 | 0.008 | 44.3 | 27 | 44 | GO:0005876; C:spindle microtubule; ISS:UniProtKB.::GO:0017053; C:transcriptional repressor complex; ISS:UniProtKB. | | | | | | | | | | GO:0008013; F:beta-catenin binding; ISS:UniProtKB.::GO:0042393; F:histone binding; ISS:UniProtKB.::GO:0003714; F:transcription corepressor activity; ISS:UniProtKB. | | | | | | | | | | GO:0060070; P:canonical Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0006508; P:proteolysis; ISS:UniProtKB.::GO:0007605; P:sensory perception of sound; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 194 | A1CUD6 | 467 | LIS11_ASPCL Nuclear distribution protein nudF... | 70 | 0.0002 | 49.3 | 40 | 60 | GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW. | 195 | Q91854 | 518 | TRCB_XENLA Beta-TrCP OS=Xenopus laevis (Afric... | 154 | 9.4 | 34.3 | 22 | 40 | | | | | | | | | | | GO:0046983; F:protein dimerization activity; IEA:InterPro. | | | | | | | | | | GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. | 196 | Q5ZIU8 | 657 | KTNB1_CHICK Katanin p80 WD40-containing subun... | 196 | 0.0002 | 49.7 | 27 | 42 | GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW. | 197 | B3NSK1 | 680 | WDR48_DROER WD repeat-containing protein 48 h... | 81 | 0.93 | 37.7 | 28 | 54 | | | | | | | | | | | | | | | | | | | | | | 198 | Q6TMK6 | 340 | GBB1_CRIGR Guanine nucleotide-binding protein... | 60 | 2.1 | 36.2 | 27 | 58 | | | | | | | | | | | GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW. | | | | | | | | | | | 199 | Q4ICM0 | 464 | LIS1_GIBZE Nuclear distribution protein PAC1 ... | 303 | 0.067 | 41.2 | 22 | 39 | GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW. | 200 | C7Z6H2 | 448 | LIS1_NECH7 Nuclear distribution protein PAC1 ... | 274 | 0.13 | 40.4 | 24 | 43 | GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW. | 201 | P54311 | 340 | GBB1_RAT Guanine nucleotide-binding protein G... | 60 | 2.3 | 36.2 | 27 | 58 | GO:0005834; C:heterotrimeric G-protein complex; TAS:RGD. | | | | | | | | | | GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0010659; P:cardiac muscle cell apoptotic process; IDA:MGI.::GO:0071456; P:cellular response to hypoxia; IDA:MGI.::GO:0007204; P:elevation of cytosolic calcium ion concentration; IMP:RGD. | 202 | P62874 | 340 | GBB1_MOUSE Guanine nucleotide-binding protein... | 60 | 2.3 | 36.2 | 27 | 58 | GO:0005834; C:heterotrimeric G-protein complex; IPI:MGI.::GO:0001750; C:photoreceptor outer segment; IDA:MGI. | | | | | | | | | | GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007200; P:activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger; IDA:MGI.::GO:0008283; P:cell proliferation; IDA:MGI.::GO:0060041; P:retina development in camera-type eye; IMP:MGI.::GO:0050909; P:sensory perception of taste; IDA:MGI. | 203 | P62873 | 340 | GBB1_HUMAN Guanine nucleotide-binding protein... | 60 | 2.3 | 36.2 | 27 | 58 | GO:0005834; C:heterotrimeric G-protein complex; IDA:MGI.::GO:0005624; C:membrane fraction; ISS:BHF-UCL. | | | | | | | | | | GO:0003924; F:GTPase activity; IDA:MGI.::GO:0051020; F:GTPase binding; IPI:UniProtKB.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007191; P:activation of adenylate cyclase activity by dopamine receptor signaling pathway; ISS:BHF-UCL.::GO:0071870; P:cellular response to catecholamine stimulus; ISS:BHF-UCL.::GO:0071377; P:cellular response to glucagon stimulus; TAS:Reactome.::GO:0071380; P:cellular response to prostaglandin E stimulus; ISS:BHF-UCL.::GO:0006112; P:energy reserve metabolic process; TAS:Reactome.::GO:0007213; P:G-protein coupled acetylcholine receptor signaling pathway; TAS:ProtInc.::GO:0030168; P:platelet activation; TAS:Reactome.::GO:0007265; P:Ras protein signal transduction; TAS:ProtInc.::GO:0007268; P:synaptic transmission; TAS:Reactome. | 204 | P62872 | 340 | GBB1_CANFA Guanine nucleotide-binding protein... | 60 | 2.3 | 36.2 | 27 | 58 | | | | | | | | | | | GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW. | | | | | | | | | | | 205 | P62871 | 340 | GBB1_BOVIN Guanine nucleotide-binding protein... | 60 | 2.3 | 36.2 | 27 | 58 | GO:0005834; C:heterotrimeric G-protein complex; IDA:BHF-UCL.::GO:0005624; C:membrane fraction; IDA:BHF-UCL. | | | | | | | | | | GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007191; P:activation of adenylate cyclase activity by dopamine receptor signaling pathway; IDA:BHF-UCL.::GO:0071870; P:cellular response to catecholamine stimulus; IDA:BHF-UCL.::GO:0071380; P:cellular response to prostaglandin E stimulus; IDA:BHF-UCL. | 206 | Q9Y297 | 605 | FBW1A_HUMAN F-box/WD repeat-containing protei... | 70 | 2.2 | 36.6 | 30 | 50 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0019005; C:SCF ubiquitin ligase complex; IDA:UniProtKB. | | | | | | | | | | GO:0046983; F:protein dimerization activity; IEA:InterPro. | | | | | | | | | | GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0043433; P:negative regulation of sequence-specific DNA binding transcription factor activity; TAS:BHF-UCL.::GO:0045879; P:negative regulation of smoothened signaling pathway; TAS:BHF-UCL.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IMP:UniProtKB.::GO:0045862; P:positive regulation of proteolysis; IMP:UniProtKB.::GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.::GO:0031648; P:protein destabilization; IMP:UniProtKB.::GO:0016032; P:viral reproduction; TAS:Reactome.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. | 207 | B4P7H8 | 680 | WDR48_DROYA WD repeat-containing protein 48 h... | 81 | 0.65 | 38.1 | 28 | 54 | | | | | | | | | | | | | | | | | | | | | | 208 | O42249 | 317 | GBLP_ORENI Guanine nucleotide-binding protein... | 105 | 0.28 | 38.9 | 29 | 50 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0030178; P:negative regulation of Wnt receptor signaling pathway; ISS:UniProtKB.::GO:2000543; P:positive regulation of gastrulation; ISS:UniProtKB.::GO:0051302; P:regulation of cell division; ISS:UniProtKB.::GO:2000114; P:regulation of establishment of cell polarity; ISS:UniProtKB.::GO:0032880; P:regulation of protein localization; ISS:UniProtKB. | 209 | B4HND9 | 680 | WDR48_DROSE WD repeat-containing protein 48 h... | 81 | 0.93 | 37.7 | 28 | 54 | | | | | | | | | | | | | | | | | | | | | | 210 | Q28YY2 | 680 | WDR48_DROPS WD repeat-containing protein 48 h... | 81 | 1.1 | 37.4 | 28 | 54 | | | | | | | | | | | | | | | | | | | | | | 211 | B4GIJ0 | 680 | WDR48_DROPE WD repeat-containing protein 48 h... | 81 | 1.1 | 37.4 | 28 | 54 | | | | | | | | | | | | | | | | | | | | | |