rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | O01761 | 8081 | UNC89_CAEEL Muscle M-line assembly protein un... | 221 | 0.41 | 39.3 | 20 | 41 | GO:0005887; C:integral to plasma membrane; IEA:InterPro.::GO:0031430; C:M band; IDA:WormBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:InterPro.::GO:0019902; F:phosphatase binding; IPI:WormBase.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0017048; F:Rho GTPase binding; IPI:WormBase.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IDA:WormBase.::GO:0005021; F:vascular endothelial growth factor-activated receptor activity; IEA:InterPro. | | | | | | | | | | GO:0040011; P:locomotion; IMP:WormBase.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.::GO:0030241; P:skeletal muscle myosin thick filament assembly; IMP:WormBase.::GO:0048010; P:vascular endothelial growth factor receptor signaling pathway; IEA:InterPro. | 2 | Q75AA0 | 1203 | PAN1_ASHGO Actin cytoskeleton-regulatory comp... | 47 | 0.004 | 45.8 | 60 | 79 | GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW. | 3 | Q8WZ42 | 34350 | TITIN_HUMAN Titin OS=Homo sapiens (Human). GN... | 182 | 0.2 | 40.4 | 20 | 37 | GO:0000794; C:condensed nuclear chromosome; IDA:BHF-UCL.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005576; C:extracellular region; TAS:Reactome.::GO:0031430; C:M band; IDA:BHF-UCL.::GO:0005865; C:striated muscle thin filament; IDA:BHF-UCL.::GO:0030018; C:Z disc; IDA:UniProtKB. | | | | | | | | | | GO:0051015; F:actin filament binding; IDA:BHF-UCL.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IDA:BHF-UCL.::GO:0005516; F:calmodulin binding; TAS:UniProtKB.::GO:0042802; F:identical protein binding; IPI:IntAct.::GO:0051371; F:muscle alpha-actinin binding; IPI:BHF-UCL.::GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0002020; F:protease binding; IPI:UniProtKB.::GO:0005515; F:protein binding; IPI:BHF-UCL.::GO:0043621; F:protein self-association; IDA:BHF-UCL.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro.::GO:0008307; F:structural constituent of muscle; TAS:UniProtKB.::GO:0031433; F:telethonin binding; ISS:BHF-UCL. | | | | | | | | | | GO:0048739; P:cardiac muscle fiber development; IMP:BHF-UCL.::GO:0055008; P:cardiac muscle tissue morphogenesis; IMP:BHF-UCL.::GO:0055003; P:cardiac myofibril assembly; IMP:BHF-UCL.::GO:0007076; P:mitotic chromosome condensation; IEP:BHF-UCL.::GO:0030049; P:muscle filament sliding; TAS:Reactome.::GO:0030168; P:platelet activation; TAS:Reactome.::GO:0002576; P:platelet degranulation; TAS:Reactome.::GO:0045859; P:regulation of protein kinase activity; IMP:BHF-UCL.::GO:0051592; P:response to calcium ion; IDA:BHF-UCL.::GO:0045214; P:sarcomere organization; IMP:BHF-UCL.::GO:0048769; P:sarcomerogenesis; IMP:BHF-UCL.::GO:0030241; P:skeletal muscle myosin thick filament assembly; IMP:BHF-UCL.::GO:0030240; P:skeletal muscle thin filament assembly; IMP:BHF-UCL.::GO:0006941; P:striated muscle contraction; TAS:UniProtKB. | 4 | A6WWW5 | 964 | IF2_OCHA4 Translation initiation factor IF-2 ... | 205 | 0.29 | 39.7 | 28 | 46 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW. | | | | | | | | | | | 5 | O13900 | 481 | SA114_SCHPO Pre-mRNA-splicing factor sap114 O... | 199 | 2.1 | 36.6 | 29 | 43 | GO:0005681; C:spliceosomal complex; IC:PomBase.::GO:0005686; C:U2 snRNP; ISS:PomBase. | | | | | | | | | | GO:0003723; F:RNA binding; ISS:PomBase. | | | | | | | | | | GO:0045292; P:nuclear mRNA cis splicing, via spliceosome; ISS:PomBase. | 6 | Q9R112 | 450 | SQRD_MOUSE Sulfide:quinone oxidoreductase, mi... | 49 | 2.7 | 36.2 | 47 | 57 | GO:0005743; C:mitochondrial inner membrane; IDA:MGI. | | | | | | | | | | GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 7 | Q32L53 | 366 | LFG1_BOVIN Protein lifeguard 1 OS=Bos taurus ... | 70 | 2.7 | 35.8 | 40 | 41 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | | | | | | | | | | | | 8 | Q60436 | 306 | SRRT_CRIGR Serrate RNA effector molecule homo... | 74 | 3.8 | 35.4 | 31 | 42 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005654; C:nucleoplasm; ISS:UniProtKB. | | | | | | | | | | GO:0003677; F:DNA binding; ISS:UniProtKB. | | | | | | | | | | GO:0008283; P:cell proliferation; ISS:UniProtKB.::GO:0097150; P:neuronal stem cell maintenance; ISS:UniProtKB.::GO:0031053; P:primary miRNA processing; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; ISS:UniProtKB. | 9 | Q1IHW4 | 123 | RS18_KORVE 30S ribosomal protein S18 OS=Korib... | 40 | 4.5 | 33.5 | 50 | 58 | GO:0005840; C:ribosome; IEA:UniProtKB-KW. | | | | | | | | | | GO:0019843; F:rRNA binding; IEA:UniProtKB-KW.::GO:0003735; F:structural constituent of ribosome; IEA:InterPro. | | | | | | | | | | GO:0006412; P:translation; IEA:InterPro. | 10 | P50111 | 915 | ZDS1_YEAST Protein ZDS1 OS=Saccharomyces cere... | 58 | 6 | 35 | 41 | 50 | GO:0005935; C:cellular bud neck; IDA:SGD.::GO:0005934; C:cellular bud tip; IDA:SGD.::GO:0005737; C:cytoplasm; IDA:SGD.::GO:0000131; C:incipient cellular bud site; IDA:SGD. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct.::GO:0008601; F:protein phosphatase type 2A regulator activity; IMP:SGD. | | | | | | | | | | GO:0007569; P:cell aging; IMP:SGD.::GO:0007047; P:cellular cell wall organization; IEA:UniProtKB-KW.::GO:0006342; P:chromatin silencing; IMP:SGD.::GO:0030010; P:establishment of cell polarity; IMP:SGD.::GO:0006406; P:mRNA export from nucleus; IMP:SGD.::GO:0010971; P:positive regulation of G2/M transition of mitotic cell cycle; IMP:SGD.::GO:0032880; P:regulation of protein localization; IMP:SGD. | 11 | P30427 | 4687 | PLEC_RAT Plectin OS=Rattus norvegicus (Rat). ... | 76 | 6.9 | 35 | 30 | 59 | GO:0016324; C:apical plasma membrane; IDA:RGD.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0030056; C:hemidesmosome; ISS:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IDA:RGD.::GO:0042383; C:sarcolemma; IDA:RGD. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0047485; F:protein N-terminus binding; IDA:RGD.::GO:0005200; F:structural constituent of cytoskeleton; IMP:RGD. | | | | | | | | | | GO:0030855; P:epithelial cell differentiation; IEP:RGD.::GO:0007565; P:female pregnancy; IEP:RGD.::GO:0031581; P:hemidesmosome assembly; ISS:UniProtKB.::GO:0007584; P:response to nutrient; IDA:RGD. | 12 | A5VTB2 | 959 | IF2_BRUO2 Translation initiation factor IF-2 ... | 107 | 7.7 | 35 | 31 | 53 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW. | | | | | | | | | | | 13 | Q8FXT2 | 959 | IF2_BRUSU Translation initiation factor IF-2 ... | 107 | 7.8 | 34.7 | 31 | 53 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW. | | | | | | | | | | | 14 | Q99N69 | 386 | LPXN_MOUSE Leupaxin OS=Mus musculus (Mouse). ... | 124 | 8.1 | 34.3 | 22 | 43 | GO:0042995; C:cell projection; IEA:UniProtKB-KW.::GO:0005925; C:focal adhesion; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0002102; C:podosome; IDA:UniProtKB. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0003712; F:transcription cofactor activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0050859; P:negative regulation of B cell receptor signaling pathway; IDA:UniProtKB.::GO:0033628; P:regulation of cell adhesion mediated by integrin; IMP:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 15 | A9M9Z4 | 959 | IF2_BRUC2 Translation initiation factor IF-2 ... | 107 | 8.4 | 34.7 | 31 | 53 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW. | | | | | | | | | | | 16 | B0CK11 | 959 | IF2_BRUSI Translation initiation factor IF-2 ... | 107 | 8.6 | 34.7 | 31 | 53 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW. | | | | | | | | | | | 17 | Q57AA0 | 959 | IF2_BRUAB Translation initiation factor IF-2 ... | 107 | 8.6 | 34.7 | 31 | 53 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW. | | | | | | | | | | | 18 | Q2YQR7 | 959 | IF2_BRUA2 Translation initiation factor IF-2 ... | 107 | 8.6 | 34.7 | 31 | 53 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW. | | | | | | | | | | | 19 | Q9JI55 | 4473 | PLEC_CRIGR Plectin OS=Cricetulus griseus (Chi... | 76 | 8.7 | 34.7 | 32 | 61 | GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0030496; C:midbody; IDA:UniProtKB. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW. | | | | | | | | | | | 20 | Q8YEB3 | 959 | IF2_BRUME Translation initiation factor IF-2 ... | 107 | 10 | 34.7 | 31 | 53 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW. | | | | | | | | | | |