rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | Q01447 | 485 | ERG24_FUSSO Delta(14)-sterol reductase OS=Fus... | 490 | 0 | 583 | 57 | 74 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0050613; F:delta14-sterol reductase activity; IEA:EC. | | | | | | | | | | GO:0016126; P:sterol biosynthetic process; IEA:UniProtKB-KW. | 2 | P38670 | 490 | ERG24_NEUCR Delta(14)-sterol reductase OS=125... | 503 | 0 | 553 | 55 | 70 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0050613; F:delta14-sterol reductase activity; IEA:EC. | | | | | | | | | | GO:0016126; P:sterol biosynthetic process; IEA:UniProtKB-KW. | 3 | O13597 | 512 | ERG24_SEPLY Delta(14)-sterol reductase OS=Sep... | 532 | 0 | 538 | 54 | 67 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0050613; F:delta14-sterol reductase activity; IEA:EC. | | | | | | | | | | GO:0016126; P:sterol biosynthetic process; IEA:UniProtKB-KW. | 4 | P78575 | 430 | ERG24_ASCIM Delta(14)-sterol reductase OS=Asc... | 479 | 3e-134 | 402 | 46 | 60 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0050613; F:delta14-sterol reductase activity; IEA:EC. | | | | | | | | | | GO:0016126; P:sterol biosynthetic process; IEA:UniProtKB-KW. | 5 | Q09195 | 424 | ERG24_SCHPO Delta(14)-sterol reductase OS=Sch... | 482 | 3e-122 | 372 | 41 | 58 | GO:0005789; C:endoplasmic reticulum membrane; ISS:PomBase.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0050613; F:delta14-sterol reductase activity; ISS:PomBase. | | | | | | | | | | GO:0006696; P:ergosterol biosynthetic process; ISS:PomBase. | 6 | Q14739 | 615 | LBR_HUMAN Lamin-B receptor OS=Homo sapiens (H... | 481 | 1e-98 | 317 | 38 | 56 | GO:0005639; C:integral to nuclear inner membrane; TAS:ProtInc. | | | | | | | | | | GO:0070087; F:chromo shadow domain binding; IPI:BHF-UCL.::GO:0003677; F:DNA binding; TAS:ProtInc.::GO:0005521; F:lamin binding; TAS:ProtInc.::GO:0016628; F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor; IEA:InterPro.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006695; P:cholesterol biosynthetic process; TAS:Reactome. | 7 | Q5R7H4 | 615 | LBR_PONAB Lamin-B receptor OS=Pongo abelii (S... | 481 | 2e-98 | 316 | 38 | 56 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005637; C:nuclear inner membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0016628; F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor; IEA:InterPro.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW. | | | | | | | | | | | 8 | O08984 | 620 | LBR_RAT Lamin-B receptor OS=Rattus norvegicus... | 486 | 3e-98 | 316 | 38 | 55 | GO:0005637; C:nuclear inner membrane; IEA:UniProtKB-SubCell.::GO:0005643; C:nuclear pore; IDA:RGD. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0016628; F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor; IEA:InterPro.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW. | | | | | | | | | | | 9 | P23913 | 637 | LBR_CHICK Lamin-B receptor OS=Gallus gallus (... | 502 | 3e-95 | 308 | 37 | 55 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005637; C:nuclear inner membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0016628; F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor; IEA:InterPro.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW. | | | | | | | | | | | 10 | Q3U9G9 | 626 | LBR_MOUSE Lamin-B receptor OS=Mus musculus (M... | 516 | 8e-94 | 304 | 36 | 53 | GO:0005637; C:nuclear inner membrane; TAS:MGI.::GO:0005652; C:nuclear lamina; TAS:MGI. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0016628; F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor; IEA:InterPro.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW. | | | | | | | | | | | 11 | O76062 | 418 | ERG24_HUMAN Delta(14)-sterol reductase OS=Hom... | 396 | 2e-91 | 292 | 41 | 57 | GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0005887; C:integral to plasma membrane; TAS:ProtInc.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0050613; F:delta14-sterol reductase activity; IEA:EC. | | | | | | | | | | GO:0006695; P:cholesterol biosynthetic process; TAS:Reactome. | 12 | Q71KT5 | 418 | ERG24_MOUSE Delta(14)-sterol reductase OS=Mus... | 479 | 1e-89 | 287 | 38 | 52 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0050613; F:delta14-sterol reductase activity; IEA:EC. | | | | | | | | | | GO:0006695; P:cholesterol biosynthetic process; IEA:UniProtKB-KW. | 13 | P32462 | 438 | ERG24_YEAST Delta(14)-sterol reductase OS=Sac... | 413 | 2e-87 | 282 | 38 | 59 | GO:0005783; C:endoplasmic reticulum; IDA:SGD.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0050613; F:delta14-sterol reductase activity; IDA:SGD. | | | | | | | | | | GO:0006696; P:ergosterol biosynthetic process; IMP:SGD. | 14 | Q8WMV1 | 418 | ERG24_BOVIN Delta(14)-sterol reductase OS=Bos... | 297 | 6e-85 | 275 | 48 | 62 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0050613; F:delta14-sterol reductase activity; IEA:EC. | | | | | | | | | | GO:0006695; P:cholesterol biosynthetic process; IEA:UniProtKB-KW. | 15 | Q54PP1 | 462 | ERG24_DICDI Delta(14)-sterol reductase OS=Dic... | 519 | 1e-67 | 231 | 33 | 47 | GO:0005789; C:endoplasmic reticulum membrane; ISS:dictyBase.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0050613; F:delta14-sterol reductase activity; ISS:dictyBase. | | | | | | | | | | GO:0006696; P:ergosterol biosynthetic process; IC:dictyBase. | 16 | Q7SXF1 | 478 | DHCR7_DANRE 7-dehydrocholesterol reductase OS... | 525 | 6e-66 | 226 | 31 | 47 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0047598; F:7-dehydrocholesterol reductase activity; IEA:EC. | | | | | | | | | | GO:0006695; P:cholesterol biosynthetic process; IEA:UniProtKB-KW. | 17 | Q6P4M0 | 473 | DHCR7_XENTR 7-dehydrocholesterol reductase OS... | 524 | 2e-64 | 222 | 30 | 47 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0047598; F:7-dehydrocholesterol reductase activity; IEA:EC. | | | | | | | | | | GO:0006695; P:cholesterol biosynthetic process; IEA:UniProtKB-KW. | 18 | Q5E9J5 | 475 | DHCR7_BOVIN 7-dehydrocholesterol reductase OS... | 533 | 3e-63 | 219 | 32 | 47 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0047598; F:7-dehydrocholesterol reductase activity; IEA:EC. | | | | | | | | | | GO:0006695; P:cholesterol biosynthetic process; IEA:UniProtKB-KW. | 19 | Q7ZXH1 | 473 | DHCR7_XENLA 7-dehydrocholesterol reductase OS... | 526 | 4e-63 | 219 | 30 | 47 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0047598; F:7-dehydrocholesterol reductase activity; IEA:EC. | | | | | | | | | | GO:0006695; P:cholesterol biosynthetic process; IEA:UniProtKB-KW. | 20 | O88455 | 471 | DHCR7_MOUSE 7-dehydrocholesterol reductase OS... | 525 | 1e-62 | 218 | 31 | 47 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0047598; F:7-dehydrocholesterol reductase activity; IDA:MGI. | | | | | | | | | | GO:0001568; P:blood vessel development; IMP:MGI.::GO:0030154; P:cell differentiation; IMP:MGI.::GO:0006695; P:cholesterol biosynthetic process; IEA:UniProtKB-KW.::GO:0030324; P:lung development; IMP:MGI.::GO:0035264; P:multicellular organism growth; IMP:MGI.::GO:0009791; P:post-embryonic development; IMP:MGI.::GO:0042127; P:regulation of cell proliferation; IMP:MGI. | 21 | Q9Z2Z8 | 471 | DHCR7_RAT 7-dehydrocholesterol reductase OS=R... | 525 | 2e-61 | 214 | 31 | 48 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IDA:RGD. | | | | | | | | | | GO:0047598; F:7-dehydrocholesterol reductase activity; IMP:RGD. | | | | | | | | | | GO:0006695; P:cholesterol biosynthetic process; IDA:RGD.::GO:0045540; P:regulation of cholesterol biosynthetic process; IDA:RGD. | 22 | Q9UBM7 | 475 | DHCR7_HUMAN 7-dehydrocholesterol reductase OS... | 530 | 5e-61 | 213 | 31 | 47 | GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0016020; C:membrane; IEA:InterPro.::GO:0005640; C:nuclear outer membrane; IDA:UniProtKB. | | | | | | | | | | GO:0047598; F:7-dehydrocholesterol reductase activity; IDA:UniProtKB.::GO:0016628; F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor; IEA:InterPro. | | | | | | | | | | GO:0006695; P:cholesterol biosynthetic process; IMP:UniProtKB. | 23 | Q9LDR4 | 369 | ERG24_ARATH Delta(14)-sterol reductase OS=Ara... | 416 | 3e-56 | 197 | 33 | 52 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0050613; F:delta14-sterol reductase activity; IMP:TAIR. | | | | | | | | | | GO:0016126; P:sterol biosynthetic process; IEA:UniProtKB-KW. | 24 | Q5UQI4 | 447 | DHCR7_MIMIV Probable 7-dehydrocholesterol red... | 428 | 3e-52 | 189 | 32 | 48 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0047598; F:7-dehydrocholesterol reductase activity; IEA:EC. | | | | | | | | | | GO:0006695; P:cholesterol biosynthetic process; IEA:UniProtKB-KW. | 25 | Q9LDU6 | 432 | ST7R_ARATH 7-dehydrocholesterol reductase OS=... | 465 | 2e-48 | 178 | 29 | 47 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; IDA:TAIR.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IDA:TAIR. | | | | | | | | | | GO:0047598; F:7-dehydrocholesterol reductase activity; IEA:EC.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0009918; F:sterol delta7 reductase activity; IMP:TAIR. | | | | | | | | | | GO:0016132; P:brassinosteroid biosynthetic process; IMP:TAIR.::GO:0006695; P:cholesterol biosynthetic process; IEA:UniProtKB-KW. | 26 | P36209 | 453 | STS1_SCHPO Delta(24(24(1)))-sterol reductase ... | 504 | 4e-33 | 134 | 28 | 42 | GO:0005789; C:endoplasmic reticulum membrane; ISS:PomBase.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0000246; F:delta24(24-1) sterol reductase activity; ISS:PomBase. | | | | | | | | | | GO:0030437; P:ascospore formation; IMP:PomBase.::GO:0071473; P:cellular response to cation stress; IMP:PomBase.::GO:0006696; P:ergosterol biosynthetic process; IMP:PomBase.::GO:0090002; P:establishment of protein localization in plasma membrane; IMP:PomBase.::GO:0071210; P:protein insertion into membrane raft; IMP:PomBase.::GO:0042493; P:response to drug; IMP:PomBase. | 27 | P25340 | 473 | ERG4_YEAST Delta(24(24(1)))-sterol reductase ... | 535 | 3e-30 | 126 | 26 | 40 | GO:0005783; C:endoplasmic reticulum; IDA:SGD.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0000246; F:delta24(24-1) sterol reductase activity; IDA:SGD. | | | | | | | | | | GO:0006696; P:ergosterol biosynthetic process; IMP:SGD. | 28 | Q8MLV1 | 741 | LBR_DROME Lamin-B receptor OS=Drosophila mela... | 497 | 8e-16 | 84 | 24 | 41 | GO:0005639; C:integral to nuclear inner membrane; IDA:UniProtKB. | | | | | | | | | | GO:0003682; F:chromatin binding; IDA:UniProtKB.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0005521; F:lamin binding; IPI:UniProtKB.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006997; P:nucleus organization; IC:UniProtKB. | 29 | Q86UP9 | 222 | LHPL3_HUMAN Lipoma HMGIC fusion partner-like ... | 83 | 0.7 | 35.4 | 28 | 42 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | | | | | | | | | | | | 30 | Q66IV3 | 218 | LHPL3_XENLA Lipoma HMGIC fusion partner-like ... | 83 | 1.3 | 34.7 | 29 | 43 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | | | | | | | | | | | |