| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
31 | Q9Z1S8 | 665 | GAB2_MOUSE GRB2-associated-binding protein 2 ... | 102 | 0.19 | 39.7 | 29 | 43 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005886; C:plasma membrane; ISS:UniProtKB. | | | | | | | | | | GO:0005547; F:phosphatidylinositol-3,4,5-trisphosphate binding; IDA:UniProtKB.::GO:0043325; F:phosphatidylinositol-3,4-bisphosphate binding; IDA:UniProtKB.::GO:0005068; F:transmembrane receptor protein tyrosine kinase adaptor activity; ISS:UniProtKB. | | | | | | | | | | GO:0030316; P:osteoclast differentiation; IMP:UniProtKB.::GO:0048015; P:phosphatidylinositol-mediated signaling; IMP:UniProtKB.::GO:0008284; P:positive regulation of cell proliferation; ISS:UniProtKB.::GO:0043306; P:positive regulation of mast cell degranulation; IMP:UniProtKB. | 32 | Q9UNA1 | 814 | RHG26_HUMAN Rho GTPase-activating protein 26 ... | 180 | 0.19 | 39.7 | 20 | 42 | GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008093; F:cytoskeletal adaptor activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005100; F:Rho GTPase activator activity; NAS:UniProtKB.::GO:0017124; F:SH3 domain binding; IEA:InterPro. | | | | | | | | | | GO:0030036; P:actin cytoskeleton organization; NAS:UniProtKB.::GO:0046847; P:filopodium assembly; IEA:InterPro.::GO:0007399; P:nervous system development; NAS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. | 33 | P63034 | 400 | CYH2_MOUSE Cytohesin-2 OS=Mus musculus (Mouse... | 126 | 0.2 | 39.3 | 29 | 40 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005886; C:plasma membrane; ISS:UniProtKB. | | | | | | | | | | GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IBA:RefGenome.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.::GO:0030155; P:regulation of cell adhesion; IBA:RefGenome. | 34 | Q2WGN9 | 574 | GAB4_HUMAN GRB2-associated-binding protein 4 ... | 143 | 0.22 | 39.7 | 27 | 43 | | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | | 35 | Q7YQL5 | 802 | OPHN1_PONPY Oligophrenin-1 OS=Pongo pygmaeus ... | 391 | 0.27 | 39.3 | 18 | 40 | GO:0030424; C:axon; IEA:UniProtKB-SubCell.::GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0043197; C:dendritic spine; IEA:UniProtKB-SubCell.::GO:0005622; C:intracellular; IEA:InterPro.::GO:0045202; C:synapse; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008093; F:cytoskeletal adaptor activity; IEA:InterPro.::GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0017124; F:SH3 domain binding; IEA:InterPro. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0046847; P:filopodium assembly; IEA:InterPro.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0007165; P:signal transduction; IEA:InterPro. | 36 | Q7YQL6 | 802 | OPHN1_PANTR Oligophrenin-1 OS=Pan troglodytes... | 391 | 0.27 | 39.3 | 18 | 40 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0043197; C:dendritic spine; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008093; F:cytoskeletal adaptor activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0017124; F:SH3 domain binding; IEA:InterPro. | | | | | | | | | | GO:0046847; P:filopodium assembly; IEA:InterPro.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0007165; P:signal transduction; IEA:InterPro. | 37 | O60890 | 802 | OPHN1_HUMAN Oligophrenin-1 OS=Homo sapiens (H... | 391 | 0.28 | 39.3 | 18 | 40 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0043197; C:dendritic spine; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008093; F:cytoskeletal adaptor activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005100; F:Rho GTPase activator activity; TAS:ProtInc.::GO:0017124; F:SH3 domain binding; IEA:InterPro. | | | | | | | | | | GO:0007411; P:axon guidance; TAS:ProtInc.::GO:0046847; P:filopodium assembly; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.::GO:0006930; P:substrate-dependent cell migration, cell extension; TAS:ProtInc. | 38 | O43150 | 1006 | ASAP2_HUMAN Arf-GAP with SH3 domain, ANK repe... | 249 | 0.35 | 38.9 | 20 | 44 | GO:0032580; C:Golgi cisterna membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro. | 39 | P63035 | 400 | CYH2_RAT Cytohesin-2 OS=Rattus norvegicus (Ra... | 126 | 0.36 | 38.5 | 30 | 40 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005886; C:plasma membrane; ISS:UniProtKB. | | | | | | | | | | GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IBA:RefGenome.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:RGD. | | | | | | | | | | GO:0016358; P:dendrite development; TAS:RGD.::GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.::GO:0030155; P:regulation of cell adhesion; IBA:RefGenome. | 40 | Q99418 | 400 | CYH2_HUMAN Cytohesin-2 OS=Homo sapiens (Human... | 126 | 0.42 | 38.5 | 30 | 40 | GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005624; C:membrane fraction; TAS:ProtInc.::GO:0005886; C:plasma membrane; IDA:UniProtKB. | | | | | | | | | | GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IBA:RefGenome.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0030036; P:actin cytoskeleton organization; TAS:ProtInc.::GO:0006897; P:endocytosis; TAS:ProtInc.::GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.::GO:0030155; P:regulation of cell adhesion; IBA:RefGenome. | 41 | Q9ST43 | 145 | PH1_ARATH Pleckstrin homology domain-containi... | 103 | 0.45 | 36.6 | 31 | 45 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | | 42 | Q7SIG6 | 958 | ASAP2_MOUSE Arf-GAP with SH3 domain, ANK repe... | 161 | 0.58 | 38.5 | 23 | 45 | GO:0032580; C:Golgi cisterna membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro. | 43 | Q76MY7 | 399 | CYH2_CHLAE Cytohesin-2 OS=Chlorocebus aethiop... | 126 | 0.69 | 37.7 | 30 | 40 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005886; C:plasma membrane; ISS:UniProtKB. | | | | | | | | | | GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro. | 44 | Q6DFV3 | 1944 | RHG21_MOUSE Rho GTPase-activating protein 21 ... | 105 | 0.72 | 38.1 | 26 | 49 | GO:0030054; C:cell junction; IEA:UniProtKB-SubCell.::GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 45 | Q5T5U3 | 1957 | RHG21_HUMAN Rho GTPase-activating protein 21 ... | 105 | 0.92 | 37.7 | 26 | 49 | GO:0030054; C:cell junction; IEA:UniProtKB-SubCell.::GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0051683; P:establishment of Golgi localization; IDA:BHF-UCL.::GO:0007030; P:Golgi organization; IMP:BHF-UCL.::GO:0051684; P:maintenance of Golgi location; IMP:BHF-UCL.::GO:0072384; P:organelle transport along microtubule; IMP:BHF-UCL.::GO:0007165; P:signal transduction; IEA:InterPro. | 46 | Q6ZQ82 | 814 | RHG26_MOUSE Rho GTPase-activating protein 26 ... | 180 | 0.97 | 37.7 | 19 | 41 | GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008093; F:cytoskeletal adaptor activity; IEA:InterPro.::GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0017124; F:SH3 domain binding; IEA:InterPro. | | | | | | | | | | GO:0046847; P:filopodium assembly; IEA:InterPro.::GO:0007165; P:signal transduction; IEA:InterPro. | 47 | Q8WWW8 | 586 | GAB3_HUMAN GRB2-associated-binding protein 3 ... | 103 | 1.5 | 37 | 29 | 46 | | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | | 48 | Q3KR37 | 738 | GRM1B_HUMAN GRAM domain-containing protein 1B... | 117 | 7.3 | 34.7 | 28 | 45 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | | | | | | | | | | | | 49 | Q7Z6J4 | 655 | FGD2_HUMAN FYVE, RhoGEF and PH domain-contain... | 80 | 1.8 | 36.6 | 30 | 49 | GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; ISS:UniProtKB.::GO:0030027; C:lamellipodium; ISS:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0032587; C:ruffle membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.::GO:0031267; F:small GTPase binding; ISS:UniProtKB. | | | | | | | | | | GO:0030036; P:actin cytoskeleton organization; ISS:UniProtKB.::GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0046847; P:filopodium assembly; ISS:UniProtKB.::GO:0008624; P:induction of apoptosis by extracellular signals; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0043088; P:regulation of Cdc42 GTPase activity; ISS:UniProtKB.::GO:0008360; P:regulation of cell shape; ISS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. | 50 | Q2KI41 | 410 | CYH2_BOVIN Cytohesin-2 OS=Bos taurus (Bovine)... | 134 | 1.9 | 36.2 | 30 | 38 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005886; C:plasma membrane; ISS:UniProtKB. | | | | | | | | | | GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; ISS:RefGenome.::GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.::GO:0030155; P:regulation of cell adhesion; ISS:RefGenome. | 51 | Q9NYU2 | 1555 | UGGG1_HUMAN UDP-glucose:glycoprotein glucosyl... | 86 | 1.9 | 36.6 | 29 | 51 | GO:0005788; C:endoplasmic reticulum lumen; TAS:Reactome.::GO:0005793; C:endoplasmic reticulum-Golgi intermediate compartment; ISS:UniProtKB. | | | | | | | | | | GO:0003980; F:UDP-glucose:glycoprotein glucosyltransferase activity; IDA:UniProtKB.::GO:0051082; F:unfolded protein binding; IDA:UniProtKB. | | | | | | | | | | GO:0051084; P:'de novo' posttranslational protein folding; TAS:UniProtKB.::GO:0043687; P:post-translational protein modification; TAS:Reactome.::GO:0018279; P:protein N-linked glycosylation via asparagine; TAS:Reactome. | 52 | Q8BWT5 | 1523 | DIP2A_MOUSE Disco-interacting protein 2 homol... | 141 | 2 | 36.6 | 28 | 41 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003824; F:catalytic activity; IEA:InterPro.::GO:0008134; F:transcription factor binding; IEA:InterPro. | | | | | | | | | | GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW. | 53 | Q6P5E4 | 1551 | UGGG1_MOUSE UDP-glucose:glycoprotein glucosyl... | 86 | 2 | 36.6 | 29 | 51 | GO:0005788; C:endoplasmic reticulum lumen; ISS:UniProtKB.::GO:0005793; C:endoplasmic reticulum-Golgi intermediate compartment; ISS:UniProtKB. | | | | | | | | | | GO:0003980; F:UDP-glucose:glycoprotein glucosyltransferase activity; ISS:UniProtKB.::GO:0051082; F:unfolded protein binding; ISS:UniProtKB. | | | | | | | | | | GO:0006486; P:protein glycosylation; IEA:InterPro. | 54 | Q9JLA3 | 1551 | UGGG1_RAT UDP-glucose:glycoprotein glucosyltr... | 86 | 2.2 | 36.6 | 29 | 51 | GO:0005788; C:endoplasmic reticulum lumen; IDA:UniProtKB.::GO:0005793; C:endoplasmic reticulum-Golgi intermediate compartment; IDA:UniProtKB. | | | | | | | | | | GO:0003980; F:UDP-glucose:glycoprotein glucosyltransferase activity; IDA:UniProtKB.::GO:0051082; F:unfolded protein binding; IDA:UniProtKB. | | | | | | | | | | GO:0051084; P:'de novo' posttranslational protein folding; TAS:UniProtKB.::GO:0006486; P:protein glycosylation; IEA:InterPro. | 55 | Q6XW15 | 3085 | POLG_BTMV Genome polyprotein OS=Beet mosaic v... | 106 | 3 | 36.2 | 21 | 51 | GO:0019028; C:viral capsid; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0004197; F:cysteine-type endopeptidase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:InterPro.::GO:0003968; F:RNA-directed RNA polymerase activity; IEA:UniProtKB-KW.::GO:0005198; F:structural molecule activity; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0018144; P:RNA-protein covalent cross-linking; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:InterPro.::GO:0019079; P:viral genome replication; IEA:InterPro. | 56 | Q9S7C0 | 831 | HSP7O_ARATH Heat shock 70 kDa protein 14 OS=A... | 132 | 3.5 | 35.8 | 23 | 46 | GO:0005829; C:cytosol; IDA:TAIR.::GO:0005634; C:nucleus; IDA:TAIR.::GO:0005886; C:plasma membrane; IDA:TAIR. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0046686; P:response to cadmium ion; IEP:TAIR.::GO:0009408; P:response to heat; IEP:TAIR. | 57 | F4HQD4 | 831 | HSP7P_ARATH Heat shock 70 kDa protein 15 OS=A... | 132 | 4.2 | 35.4 | 23 | 46 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006950; P:response to stress; IEA:UniProtKB-KW. | 58 | Q80TI0 | 738 | GRM1B_MOUSE GRAM domain-containing protein 1B... | 117 | 8.1 | 34.7 | 28 | 45 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | | | | | | | | | | | | 59 | Q10165 | 923 | CNT6_SCHPO Probable ribosylation factor GTPas... | 90 | 5 | 35.4 | 29 | 47 | GO:0032153; C:cell division site; IDA:PomBase.::GO:0051286; C:cell tip; IDA:PomBase.::GO:0005829; C:cytosol; IDA:PomBase. | | | | | | | | | | GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006886; P:intracellular protein transport; NAS:PomBase.::GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; NAS:PomBase. | 60 | Q8BLR5 | 1005 | PSD4_MOUSE PH and SEC7 domain-containing prot... | 138 | 6.2 | 35 | 28 | 42 | GO:0005737; C:cytoplasm; IBA:RefGenome.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IBA:RefGenome.::GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro. |
