| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | O13818 | 1213 | YEE2_SCHPO Uncharacterized PH domain-containi... | 1276 | 7e-79 | 288 | 24 | 41 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.::GO:0005816; C:spindle pole body; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | | 2 | P38717 | 1229 | SIP3_YEAST Protein SIP3 OS=Saccharomyces cere... | 367 | 0.001 | 47.4 | 23 | 34 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0003712; F:transcription cofactor activity; IDA:SGD. | | | | | | | | | | GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:SGD. | 3 | P38851 | 1228 | YSP1_YEAST Protein YSP1 OS=Saccharomyces cere... | 711 | 0.00000005 | 61.6 | 20 | 37 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | | 4 | Q96P50 | 834 | ACAP3_HUMAN Arf-GAP with coiled-coil, ANK rep... | 408 | 0.00000000008 | 70.5 | 20 | 40 | | | | | | | | | | | GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0008093; F:cytoskeletal adaptor activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0017124; F:SH3 domain binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0046847; P:filopodium assembly; IEA:InterPro.::GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.::GO:0007165; P:signal transduction; IEA:InterPro. | 5 | Q8NEU8 | 664 | DP13B_HUMAN DCC-interacting protein 13-beta O... | 118 | 0.000000008 | 63.9 | 35 | 53 | GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:UniProtKB. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0008283; P:cell proliferation; IDA:UniProtKB.::GO:0007165; P:signal transduction; TAS:UniProtKB. | 6 | Q8K3G9 | 662 | DP13B_MOUSE DCC-interacting protein 13-beta O... | 407 | 0.00000001 | 63.2 | 24 | 40 | GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0008283; P:cell proliferation; ISS:UniProtKB. | 7 | Q6ZQK5 | 770 | ACAP2_MOUSE Arf-GAP with coiled-coil, ANK rep... | 394 | 0.0000002 | 58.9 | 21 | 41 | | | | | | | | | | | GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro. | 8 | Q5FVC7 | 770 | ACAP2_RAT Arf-GAP with coiled-coil, ANK repea... | 394 | 0.0000002 | 58.9 | 21 | 41 | | | | | | | | | | | GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro. | 9 | Q6IVG4 | 778 | ACAP2_RABIT Arf-GAP with coiled-coil, ANK rep... | 394 | 0.0000006 | 57.8 | 21 | 41 | | | | | | | | | | | GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro. | 10 | Q15057 | 778 | ACAP2_HUMAN Arf-GAP with coiled-coil, ANK rep... | 394 | 0.0000006 | 57.8 | 21 | 40 | | | | | | | | | | | GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro. | 11 | Q5ZK62 | 781 | ACAP2_CHICK Arf-GAP with coiled-coil, ANK rep... | 391 | 0.000001 | 56.6 | 19 | 39 | | | | | | | | | | | GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro. | 12 | Q8K3H0 | 707 | DP13A_MOUSE DCC-interacting protein 13-alpha ... | 175 | 0.000008 | 54.3 | 27 | 48 | GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0008283; P:cell proliferation; ISS:UniProtKB. | 13 | Q9UKG1 | 709 | DP13A_HUMAN DCC-interacting protein 13-alpha ... | 176 | 0.00002 | 53.1 | 27 | 49 | GO:0005829; C:cytosol; IDA:BHF-UCL.::GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IDA:BHF-UCL.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0012506; C:vesicle membrane; IDA:BHF-UCL. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0043422; F:protein kinase B binding; IPI:BHF-UCL. | | | | | | | | | | GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0008283; P:cell proliferation; IDA:UniProtKB.::GO:0008286; P:insulin receptor signaling pathway; TAS:BHF-UCL.::GO:0042981; P:regulation of apoptotic process; TAS:Reactome.::GO:0090003; P:regulation of establishment of protein localization in plasma membrane; IMP:BHF-UCL.::GO:0046324; P:regulation of glucose import; IMP:BHF-UCL. | 14 | Q1AAU6 | 1144 | ASAP1_RAT Arf-GAP with SH3 domain, ANK repeat... | 247 | 0.0005 | 48.5 | 23 | 44 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0008093; F:cytoskeletal adaptor activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0017124; F:SH3 domain binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0060271; P:cilium morphogenesis; ISS:UniProtKB.::GO:0046847; P:filopodium assembly; IEA:InterPro.::GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.::GO:0007165; P:signal transduction; IEA:InterPro. | 15 | Q8TDY4 | 903 | ASAP3_HUMAN Arf-GAP with SH3 domain, ANK repe... | 120 | 0.001 | 47.4 | 28 | 48 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro. | 16 | O97902 | 1129 | ASAP1_BOVIN Arf-GAP with SH3 domain, ANK repe... | 245 | 0.002 | 47 | 22 | 43 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0008093; F:cytoskeletal adaptor activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0017124; F:SH3 domain binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0060271; P:cilium morphogenesis; ISS:UniProtKB.::GO:0046847; P:filopodium assembly; IEA:InterPro.::GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.::GO:0007165; P:signal transduction; IEA:InterPro. | 17 | Q9UUE2 | 870 | CSX2_SCHPO Protein csx2 OS=Schizosaccharomyce... | 80 | 0.003 | 45.8 | 29 | 49 | GO:0005829; C:cytosol; IDA:PomBase.::GO:0005886; C:plasma membrane; IDA:PomBase. | | | | | | | | | | GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IDA:PomBase.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0071276; P:cellular response to cadmium ion; IMP:PomBase.::GO:0006886; P:intracellular protein transport; NAS:PomBase.::GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.::GO:0046685; P:response to arsenic-containing substance; IMP:PomBase.::GO:0007264; P:small GTPase mediated signal transduction; IC:PomBase. | 18 | Q9ULH1 | 1129 | ASAP1_HUMAN Arf-GAP with SH3 domain, ANK repe... | 245 | 0.003 | 45.8 | 21 | 43 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0008093; F:cytoskeletal adaptor activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0017124; F:SH3 domain binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0060271; P:cilium morphogenesis; IMP:UniProtKB.::GO:0046847; P:filopodium assembly; IEA:InterPro.::GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.::GO:0007165; P:signal transduction; IEA:InterPro. | 19 | Q8K2H4 | 740 | ACAP1_MOUSE Arf-GAP with coiled-coil, ANK rep... | 405 | 0.005 | 45.1 | 19 | 40 | | | | | | | | | | | GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0004629; F:phospholipase C activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.::GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro. | 20 | Q99J31 | 802 | OPHN1_MOUSE Oligophrenin-1 OS=Mus musculus (M... | 400 | 0.006 | 45.1 | 17 | 40 | GO:0015629; C:actin cytoskeleton; IDA:MGI.::GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0043197; C:dendritic spine; IEA:UniProtKB-SubCell.::GO:0043195; C:terminal button; IDA:MGI. | | | | | | | | | | GO:0003779; F:actin binding; IDA:MGI.::GO:0008093; F:cytoskeletal adaptor activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005100; F:Rho GTPase activator activity; IMP:MGI.::GO:0017124; F:SH3 domain binding; IEA:InterPro. | | | | | | | | | | GO:0030036; P:actin cytoskeleton organization; IDA:MGI.::GO:0046847; P:filopodium assembly; IEA:InterPro.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0030100; P:regulation of endocytosis; IMP:MGI.::GO:0051966; P:regulation of synaptic transmission, glutamatergic; IMP:MGI.::GO:0007165; P:signal transduction; IEA:InterPro.::GO:0048488; P:synaptic vesicle endocytosis; IMP:MGI. | 21 | A1A4S6 | 786 | RHG10_HUMAN Rho GTPase-activating protein 10 ... | 427 | 0.006 | 44.7 | 18 | 38 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008093; F:cytoskeletal adaptor activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0017124; F:SH3 domain binding; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0046847; P:filopodium assembly; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. | 22 | Q9QWY8 | 1147 | ASAP1_MOUSE Arf-GAP with SH3 domain, ANK repe... | 245 | 0.008 | 44.7 | 21 | 43 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0008093; F:cytoskeletal adaptor activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0017124; F:SH3 domain binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0060271; P:cilium morphogenesis; ISS:UniProtKB.::GO:0046847; P:filopodium assembly; IEA:InterPro.::GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.::GO:0007165; P:signal transduction; IEA:InterPro. | 23 | Q5U464 | 904 | ASAP3_MOUSE Arf-GAP with SH3 domain, ANK repe... | 110 | 0.015 | 43.5 | 26 | 48 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro. | 24 | Q15027 | 740 | ACAP1_HUMAN Arf-GAP with coiled-coil, ANK rep... | 75 | 0.018 | 43.1 | 32 | 55 | | | | | | | | | | | GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0004629; F:phospholipase C activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0006629; P:lipid metabolic process; IEA:InterPro.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro. | 25 | Q5RC33 | 662 | GRM1C_PONAB GRAM domain-containing protein 1C... | 431 | 0.018 | 43.1 | 22 | 38 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | | | | | | | | | | | | 26 | P0CAX5 | 802 | OPHN1_RAT Oligophrenin-1 OS=Rattus norvegicus... | 391 | 0.025 | 42.7 | 18 | 39 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0043197; C:dendritic spine; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008093; F:cytoskeletal adaptor activity; IEA:InterPro.::GO:0035255; F:ionotropic glutamate receptor binding; IPI:RGD.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0017124; F:SH3 domain binding; IEA:InterPro. | | | | | | | | | | GO:0046847; P:filopodium assembly; IEA:InterPro.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0007165; P:signal transduction; IEA:InterPro. | 27 | Q559T8 | 2102 | Y0701_DICDI Probable serine/threonine-protein... | 109 | 0.073 | 41.6 | 26 | 48 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007154; P:cell communication; IEA:InterPro. | 28 | Q8CI52 | 457 | GRM1C_MOUSE GRAM domain-containing protein 1C... | 93 | 0.09 | 40.8 | 25 | 53 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | | | | | | | | | | | | 29 | A5PK26 | 745 | ACAP1_BOVIN Arf-GAP with coiled-coil, ANK rep... | 45 | 0.15 | 40 | 29 | 69 | | | | | | | | | | | GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro. | 30 | Q8IYS0 | 662 | GRM1C_HUMAN GRAM domain-containing protein 1C... | 430 | 0.16 | 40 | 23 | 37 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | | | | | | | | | | | | 31 | Q9Z1S8 | 665 | GAB2_MOUSE GRB2-associated-binding protein 2 ... | 102 | 0.19 | 39.7 | 29 | 43 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005886; C:plasma membrane; ISS:UniProtKB. | | | | | | | | | | GO:0005547; F:phosphatidylinositol-3,4,5-trisphosphate binding; IDA:UniProtKB.::GO:0043325; F:phosphatidylinositol-3,4-bisphosphate binding; IDA:UniProtKB.::GO:0005068; F:transmembrane receptor protein tyrosine kinase adaptor activity; ISS:UniProtKB. | | | | | | | | | | GO:0030316; P:osteoclast differentiation; IMP:UniProtKB.::GO:0048015; P:phosphatidylinositol-mediated signaling; IMP:UniProtKB.::GO:0008284; P:positive regulation of cell proliferation; ISS:UniProtKB.::GO:0043306; P:positive regulation of mast cell degranulation; IMP:UniProtKB. |
