rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
121 | Q6AXW7 | 204 | DUS18_RAT Dual specificity protein phosphatas... | 81 | 3 | 34.3 | 30 | 48 | GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IEA:InterPro.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC. | | | | | | | | | | | 122 | Q9SRK5 | 282 | LSF2_ARATH Phosphoglucan phosphatase LSF2, ch... | 58 | 3.2 | 34.7 | 36 | 57 | GO:0009507; C:chloroplast; IDA:TAIR. | | | | | | | | | | GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro. | | | | | | | | | | GO:0006470; P:protein dephosphorylation; IEA:InterPro. | 123 | P60484 | 403 | PTEN_HUMAN Phosphatidylinositol 3,4,5-trispho... | 49 | 3.3 | 34.7 | 35 | 55 | GO:0042995; C:cell projection; IDA:UniProtKB.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0009898; C:internal side of plasma membrane; IDA:UniProtKB.::GO:0035749; C:myelin sheath adaxonal region; ISS:BHF-UCL.::GO:0016605; C:PML body; IEA:UniProtKB-SubCell.::GO:0043220; C:Schmidt-Lanterman incisure; ISS:BHF-UCL.::GO:0019717; C:synaptosome; ISS:BHF-UCL. | | | | | | | | | | GO:0010997; F:anaphase-promoting complex binding; IPI:BHF-UCL.::GO:0051717; F:inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity; IDA:UniProtKB.::GO:0008289; F:lipid binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030165; F:PDZ domain binding; IPI:UniProtKB.::GO:0016314; F:phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity; IDA:UniProtKB.::GO:0051800; F:phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity; IDA:UniProtKB.::GO:0004438; F:phosphatidylinositol-3-phosphatase activity; IDA:UniProtKB.::GO:0004722; F:protein serine/threonine phosphatase activity; IDA:UniProtKB.::GO:0004725; F:protein tyrosine phosphatase activity; IDA:UniProtKB.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro. | | | | | | | | | | GO:0007092; P:activation of mitotic anaphase-promoting complex activity; IDA:BHF-UCL.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0060070; P:canonical Wnt receptor signaling pathway; IDA:BHF-UCL.::GO:0008283; P:cell proliferation; TAS:UniProtKB.::GO:0032286; P:central nervous system myelin maintenance; ISS:BHF-UCL.::GO:0021955; P:central nervous system neuron axonogenesis; ISS:BHF-UCL.::GO:0060997; P:dendritic spine morphogenesis; ISS:BHF-UCL.::GO:0021542; P:dentate gyrus development; ISS:BHF-UCL.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.::GO:0048853; P:forebrain morphogenesis; ISS:BHF-UCL.::GO:0006917; P:induction of apoptosis; ISS:UniProtKB.::GO:0046855; P:inositol phosphate dephosphorylation; IDA:UniProtKB.::GO:0007611; P:learning or memory; ISS:BHF-UCL.::GO:0045475; P:locomotor rhythm; ISS:BHF-UCL.::GO:0033555; P:multicellular organismal response to stress; ISS:BHF-UCL.::GO:0050771; P:negative regulation of axonogenesis; ISS:BHF-UCL.::GO:0030336; P:negative regulation of cell migration; IMP:UniProtKB.::GO:0045792; P:negative regulation of cell size; ISS:BHF-UCL.::GO:0031658; P:negative regulation of cyclin-dependent protein kinase activity involved in G1/S; IDA:BHF-UCL.::GO:0061002; P:negative regulation of dendritic spine morphogenesis; ISS:BHF-UCL.::GO:0090394; P:negative regulation of excitatory postsynaptic membrane potential; ISS:BHF-UCL.::GO:0051895; P:negative regulation of focal adhesion assembly; IMP:UniProtKB.::GO:2000134; P:negative regulation of G1/S transition of mitotic cell cycle; IDA:BHF-UCL.::GO:0046621; P:negative regulation of organ growth; ISS:BHF-UCL.::GO:0014067; P:negative regulation of phosphatidylinositol 3-kinase cascade; TAS:BHF-UCL.::GO:0051898; P:negative regulation of protein kinase B signaling cascade; IMP:UniProtKB.::GO:0001933; P:negative regulation of protein phosphorylation; IDA:BHF-UCL.::GO:2000808; P:negative regulation of synaptic vesicle clustering; ISS:BHF-UCL.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0007270; P:neuron-neuron synaptic transmission; ISS:BHF-UCL.::GO:0046856; P:phosphatidylinositol dephosphorylation; IDA:UniProtKB.::GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:Reactome.::GO:0008284; P:positive regulation of cell proliferation; ISS:BHF-UCL.::GO:2000463; P:positive regulation of excitatory postsynaptic membrane potential; ISS:BHF-UCL.::GO:2000060; P:positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IDA:BHF-UCL.::GO:0051091; P:positive regulation of sequence-specific DNA binding transcription factor activity; IMP:BHF-UCL.::GO:0097107; P:postsynaptic density assembly; ISS:BHF-UCL.::GO:0060134; P:prepulse inhibition; ISS:BHF-UCL.::GO:0097105; P:presynaptic membrane assembly; ISS:BHF-UCL.::GO:0043491; P:protein kinase B signaling cascade; ISS:UniProtKB.::GO:0050821; P:protein stabilization; IDA:BHF-UCL.::GO:0060024; P:rhythmic synaptic transmission; ISS:BHF-UCL.::GO:0035176; P:social behavior; ISS:BHF-UCL.::GO:0060074; P:synapse maturation; ISS:BHF-UCL.::GO:0050852; P:T cell receptor signaling pathway; TAS:Reactome. | 124 | P60483 | 403 | PTEN_CANFA Phosphatidylinositol 3,4,5-trispho... | 49 | 3.3 | 34.7 | 35 | 55 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0016605; C:PML body; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0051717; F:inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030165; F:PDZ domain binding; ISS:UniProtKB.::GO:0016314; F:phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity; ISS:UniProtKB.::GO:0051800; F:phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity; ISS:UniProtKB.::GO:0004438; F:phosphatidylinositol-3-phosphatase activity; ISS:UniProtKB.::GO:0004722; F:protein serine/threonine phosphatase activity; ISS:UniProtKB.::GO:0004725; F:protein tyrosine phosphatase activity; ISS:UniProtKB.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007417; P:central nervous system development; ISS:UniProtKB.::GO:0006917; P:induction of apoptosis; ISS:UniProtKB.::GO:0046855; P:inositol phosphate dephosphorylation; ISS:UniProtKB.::GO:0030336; P:negative regulation of cell migration; ISS:UniProtKB.::GO:0051895; P:negative regulation of focal adhesion assembly; ISS:UniProtKB.::GO:0051898; P:negative regulation of protein kinase B signaling cascade; ISS:UniProtKB.::GO:0046856; P:phosphatidylinositol dephosphorylation; ISS:UniProtKB.::GO:0043491; P:protein kinase B signaling cascade; ISS:UniProtKB.::GO:0010975; P:regulation of neuron projection development; ISS:UniProtKB. | 125 | O08586 | 403 | PTEN_MOUSE Phosphatidylinositol 3,4,5-trispho... | 49 | 3.4 | 34.7 | 35 | 55 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0035749; C:myelin sheath adaxonal region; IDA:BHF-UCL.::GO:0016605; C:PML body; IEA:UniProtKB-SubCell.::GO:0043220; C:Schmidt-Lanterman incisure; IDA:BHF-UCL.::GO:0019717; C:synaptosome; IDA:BHF-UCL. | | | | | | | | | | GO:0051717; F:inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030165; F:PDZ domain binding; ISS:UniProtKB.::GO:0016314; F:phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity; ISS:UniProtKB.::GO:0051800; F:phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity; ISS:UniProtKB.::GO:0004438; F:phosphatidylinositol-3-phosphatase activity; ISS:UniProtKB.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0004722; F:protein serine/threonine phosphatase activity; ISS:UniProtKB.::GO:0004725; F:protein tyrosine phosphatase activity; ISS:UniProtKB.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro. | | | | | | | | | | GO:0007092; P:activation of mitotic anaphase-promoting complex activity; IMP:BHF-UCL.::GO:0001525; P:angiogenesis; IMP:MGI.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0048738; P:cardiac muscle tissue development; IMP:MGI.::GO:0032286; P:central nervous system myelin maintenance; IMP:BHF-UCL.::GO:0021955; P:central nervous system neuron axonogenesis; IMP:BHF-UCL.::GO:0060997; P:dendritic spine morphogenesis; IMP:BHF-UCL.::GO:0021542; P:dentate gyrus development; IMP:BHF-UCL.::GO:0043542; P:endothelial cell migration; IMP:MGI.::GO:0048853; P:forebrain morphogenesis; IMP:BHF-UCL.::GO:0006917; P:induction of apoptosis; IMP:MGI.::GO:0046855; P:inositol phosphate dephosphorylation; ISS:UniProtKB.::GO:0007611; P:learning or memory; IMP:BHF-UCL.::GO:0045475; P:locomotor rhythm; IMP:BHF-UCL.::GO:0060291; P:long-term synaptic potentiation; IMP:BHF-UCL.::GO:0060179; P:male mating behavior; IMP:BHF-UCL.::GO:0042711; P:maternal behavior; IMP:BHF-UCL.::GO:0033555; P:multicellular organismal response to stress; IMP:BHF-UCL.::GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.::GO:0050771; P:negative regulation of axonogenesis; IMP:BHF-UCL.::GO:0090344; P:negative regulation of cell aging; IMP:BHF-UCL.::GO:0030336; P:negative regulation of cell migration; ISS:UniProtKB.::GO:0045792; P:negative regulation of cell size; IMP:BHF-UCL.::GO:0061002; P:negative regulation of dendritic spine morphogenesis; IMP:BHF-UCL.::GO:0050680; P:negative regulation of epithelial cell proliferation; IMP:MGI.::GO:0090394; P:negative regulation of excitatory postsynaptic membrane potential; IMP:BHF-UCL.::GO:0051895; P:negative regulation of focal adhesion assembly; ISS:UniProtKB.::GO:0031642; P:negative regulation of myelination; IMP:MGI.::GO:0046621; P:negative regulation of organ growth; IMP:BHF-UCL.::GO:0051898; P:negative regulation of protein kinase B signaling cascade; IMP:UniProtKB.::GO:0090071; P:negative regulation of ribosome biogenesis; IMP:BHF-UCL.::GO:2000808; P:negative regulation of synaptic vesicle clustering; IMP:BHF-UCL.::GO:0007270; P:neuron-neuron synaptic transmission; IMP:BHF-UCL.::GO:0046856; P:phosphatidylinositol dephosphorylation; ISS:UniProtKB.::GO:0008284; P:positive regulation of cell proliferation; IMP:BHF-UCL.::GO:2000463; P:positive regulation of excitatory postsynaptic membrane potential; IMP:BHF-UCL.::GO:0097107; P:postsynaptic density assembly; IMP:BHF-UCL.::GO:0060134; P:prepulse inhibition; IMP:BHF-UCL.::GO:0097105; P:presynaptic membrane assembly; IMP:BHF-UCL.::GO:0060736; P:prostate gland growth; IMP:MGI.::GO:0043491; P:protein kinase B signaling cascade; IMP:UniProtKB.::GO:0002902; P:regulation of B cell apoptotic process; IMP:MGI.::GO:0033032; P:regulation of myeloid cell apoptotic process; IMP:MGI.::GO:0060024; P:rhythmic synaptic transmission; IMP:BHF-UCL.::GO:0035176; P:social behavior; IMP:BHF-UCL.::GO:0060074; P:synapse maturation; IMP:BHF-UCL. | 126 | A3LZ57 | 2212 | SEC16_PICST COPII coat assembly protein SEC16... | 188 | 3.6 | 35 | 22 | 43 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0048208; P:COPII vesicle coating; IEA:InterPro.::GO:0015031; P:protein transport; IEA:UniProtKB-KW. | 127 | P07676 | 382 | TRFA_ECOLX TrfA transcriptional repressor pro... | 50 | 5.2 | 34.3 | 36 | 54 | | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 128 | Q5R8X2 | 188 | DUS18_PONAB Dual specificity protein phosphat... | 56 | 5.9 | 33.1 | 34 | 57 | GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IEA:InterPro.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC. | | | | | | | | | | | 129 | Q4G0W2 | 176 | DUS28_HUMAN Dual specificity phosphatase 28 O... | 98 | 6.3 | 33.1 | 28 | 44 | | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IBA:RefGenome. | | | | | | | | | | | 130 | Q5BIP9 | 188 | DUS18_BOVIN Dual specificity protein phosphat... | 56 | 6.7 | 33.1 | 34 | 54 | GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IEA:InterPro.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC. | | | | | | | | | | | 131 | Q3ARP5 | 293 | LIPA_CHLCH Lipoyl synthase OS=Chlorobium chlo... | 120 | 7.3 | 33.5 | 27 | 48 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0016992; F:lipoate synthase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | | 132 | Q9Y6J8 | 313 | STYL1_HUMAN Serine/threonine/tyrosine-interac... | 83 | 9.6 | 33.1 | 28 | 49 | GO:0005622; C:intracellular; TAS:GOC. | | | | | | | | | | GO:0004721; F:phosphoprotein phosphatase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; TAS:ProtInc. |