Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Blastomyces dermatitidis ER-3
Locus:
BDCG_00486
Length:
423
Number of sequences:
9522
Description:
mitogen-activated protein kinase MKC1
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
361P17157    305   PHO85_YEAST Cyclin-dependent protein kinase P...3121e-43     160     34     51GO:0000307; C:cyclin-dependent protein kinase holoenzyme complex; IPI:SGD.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IDA:SGD.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0050849; P:negative regulation of calcium-mediated signaling; IGI:SGD.::GO:0045719; P:negative regulation of glycogen biosynthetic process; IMP:SGD.::GO:0016242; P:negative regulation of macroautophagy; IMP:SGD.::GO:0045936; P:negative regulation of phosphate metabolic process; IGI:SGD.::GO:0043433; P:negative regulation of sequence-specific DNA binding transcription factor activity; IMP:SGD.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IGI:SGD.::GO:0016239; P:positive regulation of macroautophagy; IMP:SGD.::GO:0032878; P:regulation of establishment or maintenance of cell polarity; IGI:SGD.::GO:0032880; P:regulation of protein localization; IDA:SGD.::GO:0031647; P:regulation of protein stability; IMP:SGD.::GO:0000083; P:regulation of transcription involved in G1/S phase of mitotic cell cycle; IMP:SGD.::GO:0006974; P:response to DNA damage stimulus; IMP:SGD.
362P79432    303   CDK4_PIG Cyclin-dependent kinase 4 OS=Sus scr...3071e-43     160     35     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
GO:0051301; P:cell division; IEA:UniProtKB-KW.
363Q5EAB2    372   CDK9_BOVIN Cyclin-dependent kinase 9 OS=Bos t...3041e-43     162     34     50GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016605; C:PML body; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
364B2MVY4    303   CDK4_SHEEP Cyclin-dependent kinase 4 OS=Ovis ...3071e-43     160     35     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
GO:0051301; P:cell division; IEA:UniProtKB-KW.
365Q32KY4    303   CDK4_BOVIN Cyclin-dependent kinase 4 OS=Bos t...3071e-43     160     35     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
GO:0051301; P:cell division; IEA:UniProtKB-KW.
366Q69ZA1    1511   CDK13_MOUSE Cyclin-dependent kinase 13 OS=Mus...3121e-43     169     36     52GO:0019908; C:nuclear cyclin-dependent protein kinase holoenzyme complex; IDA:UniProtKB.::GO:0016607; C:nuclear speck; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030332; F:cyclin binding; IPI:UniProtKB.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; ISS:UniProtKB.
GO:0000380; P:alternative nuclear mRNA splicing, via spliceosome; IDA:UniProtKB.::GO:0030097; P:hemopoiesis; ISS:UniProtKB.::GO:0070816; P:phosphorylation of RNA polymerase II C-terminal domain; ISS:UniProtKB.
367P51139    411   MSK3_MEDSA Glycogen synthase kinase-3 homolog...3341e-43     162     34     51
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
368Q4KM47    358   CDK10_RAT Cyclin-dependent kinase 10 OS=Rattu...3081e-43     161     36     53
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
369Q00646    323   CDK1_EMENI Cyclin-dependent kinase 1 OS=194 /...3161e-43     160     33     50
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
370Q66HE7    352   CDKL1_RAT Cyclin-dependent kinase-like 1 OS=R...3111e-43     161     32     50GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005625; C:soluble fraction; IDA:RGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
GO:0007507; P:heart development; IEP:RGD.
371P30285    303   CDK4_MOUSE Cyclin-dependent kinase 4 OS=Mus m...3032e-43     159     35     49GO:0000307; C:cyclin-dependent protein kinase holoenzyme complex; IPI:MGI.::GO:0005667; C:transcription factor complex; IDA:MGI.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IDA:MGI.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0051726; P:regulation of cell cycle; IDA:MGI.::GO:0007165; P:signal transduction; IDA:MGI.
372P50750    372   CDK9_HUMAN Cyclin-dependent kinase 9 OS=Homo ...3042e-43     161     34     50GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016605; C:PML body; IDA:UniProtKB.::GO:0008023; C:transcription elongation factor complex; TAS:ProtInc.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; TAS:ProtInc.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IDA:UniProtKB.
GO:0008283; P:cell proliferation; TAS:ProtInc.::GO:0071345; P:cellular response to cytokine stimulus; IDA:UniProtKB.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0071157; P:negative regulation of cell cycle arrest; IDA:UniProtKB.::GO:0050434; P:positive regulation of viral transcription; TAS:Reactome.::GO:0006282; P:regulation of DNA repair; IDA:UniProtKB.::GO:0031056; P:regulation of histone modification; IDA:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0043111; P:replication fork arrest; IDA:UniProtKB.::GO:0006368; P:transcription elongation from RNA polymerase II promoter; TAS:Reactome.::GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:ProtInc.::GO:0016032; P:viral reproduction; TAS:Reactome.
373Q92241    304   PHO85_KLULA Negative regulator of the PHO sys...3162e-43     159     33     52
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
374P35426    303   CDK4_RAT Cyclin-dependent kinase 4 OS=Rattus ...3033e-43     159     35     49GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:RGD.::GO:0048471; C:perinuclear region of cytoplasm; IDA:RGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030332; F:cyclin binding; IPI:RGD.::GO:0004693; F:cyclin-dependent protein kinase activity; IDA:RGD.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007623; P:circadian rhythm; IEP:RGD.::GO:0031100; P:organ regeneration; IEP:RGD.::GO:0043065; P:positive regulation of apoptotic process; IMP:RGD.::GO:0045787; P:positive regulation of cell cycle; TAS:RGD.::GO:0008284; P:positive regulation of cell proliferation; IMP:RGD.::GO:0045793; P:positive regulation of cell size; IMP:RGD.::GO:0045727; P:positive regulation of translation; IMP:RGD.::GO:0055093; P:response to hyperoxia; IEP:RGD.::GO:0010288; P:response to lead ion; IMP:RGD.::GO:0033574; P:response to testosterone stimulus; IDA:RGD.::GO:0009636; P:response to toxin; IEP:RGD.
375Q3UMM4    360   CDK10_MOUSE Cyclin-dependent kinase 10 OS=Mus...3083e-43     160     36     52
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
376Q2NL51    490   GSK3A_MOUSE Glycogen synthase kinase-3 alpha ...3693e-43     163     32     49
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IDA:MGI.::GO:0050321; F:tau-protein kinase activity; IEA:EC.
GO:0003214; P:cardiac left ventricle morphogenesis; IMP:BHF-UCL.::GO:0016477; P:cell migration; IGI:MGI.::GO:0071285; P:cellular response to lithium ion; IDA:MGI.::GO:0071407; P:cellular response to organic cyclic compound; IDA:MGI.::GO:0005977; P:glycogen metabolic process; IEA:UniProtKB-KW.::GO:0044027; P:hypermethylation of CpG island; IMP:BHF-UCL.::GO:0008286; P:insulin receptor signaling pathway; IDA:BHF-UCL.::GO:0061052; P:negative regulation of cell growth involved in cardiac muscle cell development; IMP:BHF-UCL.::GO:0032007; P:negative regulation of TOR signaling cascade; IMP:BHF-UCL.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0071879; P:positive regulation of adrenergic receptor signaling pathway; IMP:BHF-UCL.::GO:0030819; P:positive regulation of cAMP biosynthetic process; IMP:BHF-UCL.::GO:2000467; P:positive regulation of glycogen (starch) synthase activity; IMP:BHF-UCL.::GO:0045823; P:positive regulation of heart contraction; IMP:BHF-UCL.::GO:0033138; P:positive regulation of peptidyl-serine phosphorylation; IDA:MGI.::GO:0010800; P:positive regulation of peptidyl-threonine phosphorylation; IDA:MGI.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.::GO:0006349; P:regulation of gene expression by genetic imprinting; IMP:BHF-UCL.::GO:0003073; P:regulation of systemic arterial blood pressure; IMP:BHF-UCL.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
377O35832    451   CKD18_RAT Cyclin-dependent kinase 18 OS=Rattu...2993e-43     162     35     52
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
378P51138    411   MSK2_MEDSA Glycogen synthase kinase-3 homolog...3323e-43     161     35     52
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
379P49840    483   GSK3A_HUMAN Glycogen synthase kinase-3 alpha ...3883e-43     162     31     48GO:0030877; C:beta-catenin destruction complex; TAS:UniProtKB.::GO:0005829; C:cytosol; TAS:BHF-UCL.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0034236; F:protein kinase A catalytic subunit binding; IPI:BHF-UCL.::GO:0004674; F:protein serine/threonine kinase activity; IDA:BHF-UCL.::GO:0050321; F:tau-protein kinase activity; TAS:UniProtKB.
GO:0006987; P:activation of signaling protein activity involved in unfolded protein response; TAS:Reactome.::GO:0003214; P:cardiac left ventricle morphogenesis; ISS:BHF-UCL.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.::GO:0005977; P:glycogen metabolic process; IEA:UniProtKB-KW.::GO:0008286; P:insulin receptor signaling pathway; ISS:BHF-UCL.::GO:0090090; P:negative regulation of canonical Wnt receptor signaling pathway; TAS:UniProtKB.::GO:0061052; P:negative regulation of cell growth involved in cardiac muscle cell development; ISS:BHF-UCL.::GO:0046325; P:negative regulation of glucose import; IMP:BHF-UCL.::GO:2000466; P:negative regulation of glycogen (starch) synthase activity; TAS:UniProtKB.::GO:0045719; P:negative regulation of glycogen biosynthetic process; TAS:UniProtKB.::GO:0046627; P:negative regulation of insulin receptor signaling pathway; IMP:BHF-UCL.::GO:0032007; P:negative regulation of TOR signaling cascade; ISS:BHF-UCL.::GO:2000077; P:negative regulation of type B pancreatic cell development; TAS:UniProtKB.::GO:0010905; P:negative regulation of UDP-glucose catabolic process; IC:UniProtKB.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:Reactome.::GO:0071879; P:positive regulation of adrenergic receptor signaling pathway; ISS:BHF-UCL.::GO:0030819; P:positive regulation of cAMP biosynthetic process; ISS:BHF-UCL.::GO:2000467; P:positive regulation of glycogen (starch) synthase activity; ISS:BHF-UCL.::GO:0045823; P:positive regulation of heart contraction; ISS:BHF-UCL.::GO:0045732; P:positive regulation of protein catabolic process; NAS:BHF-UCL.::GO:0003073; P:regulation of systemic arterial blood pressure; ISS:BHF-UCL.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
380Q15131    360   CDK10_HUMAN Cyclin-dependent kinase 10 OS=Hom...3084e-43     160     36     52
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; TAS:ProtInc.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0008285; P:negative regulation of cell proliferation; TAS:ProtInc.::GO:0007089; P:traversing start control point of mitotic cell cycle; TAS:ProtInc.
381Q96VK3    544   BUR1_EMENI Serine/threonine-protein kinase bu...2994e-43     163     34     51GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
382Q5XIT0    507   CDKL2_RAT Cyclin-dependent kinase-like 2 OS=R...3104e-43     162     34     52GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
383Q91757    420   GSK3B_XENLA Glycogen synthase kinase-3 beta O...3384e-43     161     33     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.::GO:0050321; F:tau-protein kinase activity; IEA:EC.
GO:0060070; P:canonical Wnt receptor signaling pathway; IDA:BHF-UCL.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:BHF-UCL.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.
384Q3MJK5    1484   CDK12_RAT Cyclin-dependent kinase 12 OS=Rattu...3124e-43     167     35     52GO:0019908; C:nuclear cyclin-dependent protein kinase holoenzyme complex; IDA:UniProtKB.::GO:0016607; C:nuclear speck; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030332; F:cyclin binding; IPI:UniProtKB.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; ISS:UniProtKB.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0070816; P:phosphorylation of RNA polymerase II C-terminal domain; ISS:UniProtKB.::GO:0043405; P:regulation of MAP kinase activity; ISS:UniProtKB.::GO:0008380; P:RNA splicing; IMP:UniProtKB.
385Q3UTQ8    938   CDKL5_MOUSE Cyclin-dependent kinase-like 5 OS...2985e-43     166     36     55GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
386Q9UQ88    783   CD11A_HUMAN Cyclin-dependent kinase 11A OS=Ho...3045e-43     165     33     52GO:0005737; C:cytoplasm; IDA:HPA.::GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
GO:0006915; P:apoptotic process; NAS:UniProtKB.::GO:0007067; P:mitosis; NAS:UniProtKB.::GO:0001558; P:regulation of cell growth; IEP:UniProtKB.::GO:0050684; P:regulation of mRNA processing; IDA:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; NAS:UniProtKB.
387E1BB50    1264   CDK12_BOVIN Cyclin-dependent kinase 12 OS=Bos...3315e-43     167     34     51GO:0019908; C:nuclear cyclin-dependent protein kinase holoenzyme complex; ISS:UniProtKB.::GO:0016607; C:nuclear speck; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; ISS:UniProtKB.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0070816; P:phosphorylation of RNA polymerase II C-terminal domain; ISS:UniProtKB.::GO:0043405; P:regulation of MAP kinase activity; ISS:UniProtKB.::GO:0008380; P:RNA splicing; ISS:UniProtKB.
388Q2TBL8    361   CDK10_BOVIN Cyclin-dependent kinase 10 OS=Bos...3086e-43     159     35     52
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
389P18265    483   GSK3A_RAT Glycogen synthase kinase-3 alpha OS...3696e-43     162     33     49GO:0005829; C:cytosol; TAS:Reactome.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0034236; F:protein kinase A catalytic subunit binding; IPI:BHF-UCL.::GO:0004674; F:protein serine/threonine kinase activity; IDA:BHF-UCL.::GO:0050321; F:tau-protein kinase activity; IEA:EC.
GO:0005977; P:glycogen metabolic process; IEA:UniProtKB-KW.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
390Q6GLD8    376   CDK9_XENTR Cyclin-dependent kinase 9 OS=Xenop...3167e-43     159     34     50GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
391O76039    1030   CDKL5_HUMAN Cyclin-dependent kinase-like 5 OS...2981e-42     165     36     55GO:0032839; C:dendrite cytoplasm; ISS:BHF-UCL.::GO:0044294; C:dendritic growth cone; ISS:BHF-UCL.::GO:0005634; C:nucleus; IDA:HGNC.
GO:0005524; F:ATP binding; IDA:HGNC.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0048365; F:Rac GTPase binding; ISS:BHF-UCL.
GO:0001764; P:neuron migration; ISS:BHF-UCL.::GO:0045773; P:positive regulation of axon extension; ISS:BHF-UCL.::GO:0050775; P:positive regulation of dendrite morphogenesis; ISS:BHF-UCL.::GO:0032855; P:positive regulation of Rac GTPase activity; ISS:BHF-UCL.::GO:0046777; P:protein autophosphorylation; IDA:HGNC.
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