Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Blastomyces dermatitidis ER-3
Locus:
BDCG_00432
Length:
1332
Number of sequences:
9522
Description:
HECT domain-containing protein
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1Q757T0    839   HUL4_ASHGO Probable E3 ubiquitin-protein liga...4473e-34     145     26     45GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0004842; F:ubiquitin-protein ligase activity; ISS:RefGenome.
GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ISS:RefGenome.
2Q05086    875   UBE3A_HUMAN Ubiquitin-protein ligase E3A OS=H...1852e-27     124     39     61GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
GO:0007420; P:brain development; TAS:ProtInc.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0070936; P:protein K48-linked ubiquitination; IDA:UniProtKB.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.
3O08759    885   UBE3A_MOUSE Ubiquitin-protein ligase E3A OS=M...1823e-26     120     40     60GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.
GO:0070936; P:protein K48-linked ubiquitination; ISS:UniProtKB.
4Q15034    1050   HERC3_HUMAN Probable E3 ubiquitin-protein lig...2991e-22     108     31     50GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.
GO:0004842; F:ubiquitin-protein ligase activity; IBA:RefGenome.
GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.
5Q5U5R9    776   HECD2_HUMAN Probable E3 ubiquitin-protein lig...1905e-24     113     35     56GO:0005622; C:intracellular; IEA:InterPro.
GO:0004842; F:ubiquitin-protein ligase activity; IBA:RefGenome.
GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.
6Q5RD78    776   HECD2_PONAB Probable E3 ubiquitin-protein lig...1903e-24     113     35     56GO:0005622; C:intracellular; IEA:InterPro.
GO:0016881; F:acid-amino acid ligase activity; IEA:InterPro.
GO:0006464; P:protein modification process; IEA:InterPro.
7Q8CDU6    774   HECD2_MOUSE Probable E3 ubiquitin-protein lig...1901e-24     115     35     56GO:0005622; C:intracellular; IEA:InterPro.
GO:0004842; F:ubiquitin-protein ligase activity; IBA:RefGenome.
GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.
8Q5GLZ8    1057   HERC4_HUMAN Probable E3 ubiquitin-protein lig...3016e-21     103     28     51GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.
GO:0004842; F:ubiquitin-protein ligase activity; IBA:RefGenome.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.::GO:0007283; P:spermatogenesis; ISS:UniProtKB.
9Q6PAV2    1057   HERC4_MOUSE Probable E3 ubiquitin-protein lig...2383e-26     120     31     53GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.
GO:0004842; F:ubiquitin-protein ligase activity; TAS:UniProtKB.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.::GO:0007283; P:spermatogenesis; IMP:UniProtKB.
10Q5PQN1    1057   HERC4_RAT Probable E3 ubiquitin-protein ligas...2381e-26     122     31     53GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.
GO:0004842; F:ubiquitin-protein ligase activity; IBA:RefGenome.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.::GO:0007283; P:spermatogenesis; ISS:UniProtKB.
11Q76N89    1606   HECW1_HUMAN E3 ubiquitin-protein ligase HECW1...1870.00000002     62.8     29     44GO:0005737; C:cytoplasm; IDA:HPA.::GO:0005634; C:nucleus; IDA:HPA.
GO:0004842; F:ubiquitin-protein ligase activity; IBA:RefGenome.
GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.
12Q6I6G8    1578   HECW2_MOUSE E3 ubiquitin-protein ligase HECW2...1920.0000000005     68.2     30     45GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004842; F:ubiquitin-protein ligase activity; IBA:RefGenome.
GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.
13Q9P2P5    1572   HECW2_HUMAN E3 ubiquitin-protein ligase HECW2...1900.0000000004     68.6     29     45GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004842; F:ubiquitin-protein ligase activity; IBA:RefGenome.
GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.
14Q9UII4    1024   HERC5_HUMAN E3 ISG15--protein ligase HERC5 OS...1664e-16     88.2     36     52GO:0005829; C:cytosol; TAS:Reactome.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0042296; F:ISG15 ligase activity; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IBA:RefGenome.
GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.::GO:0045087; P:innate immune response; TAS:Reactome.::GO:0032020; P:ISG15-protein conjugation; IDA:UniProtKB.::GO:0032480; P:negative regulation of type I interferon production; TAS:Reactome.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.::GO:0000079; P:regulation of cyclin-dependent protein kinase activity; TAS:ProtInc.::GO:0050688; P:regulation of defense response to virus; IDA:UniProtKB.::GO:0009615; P:response to virus; IEA:UniProtKB-KW.
15Q8K4P8    1604   HECW1_MOUSE E3 ubiquitin-protein ligase HECW1...1860.00000002     62.8     28     45GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004842; F:ubiquitin-protein ligase activity; IBA:RefGenome.
GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.
16Q9VVI3    1007   NEDD4_DROME E3 ubiquitin-protein ligase Nedd-...1350.0000002     59.3     30     52GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005886; C:plasma membrane; IDA:FlyBase.
GO:0005112; F:Notch binding; IPI:UniProtKB.::GO:0019904; F:protein domain specific binding; IDA:FlyBase.::GO:0004842; F:ubiquitin-protein ligase activity; NAS:UniProtKB.
GO:0016199; P:axon midline choice point recognition; IMP:UniProtKB.::GO:0045746; P:negative regulation of Notch signaling pathway; IMP:UniProtKB.::GO:0007528; P:neuromuscular junction development; IMP:FlyBase.::GO:0007219; P:Notch signaling pathway; IEA:UniProtKB-KW.::GO:0002092; P:positive regulation of receptor internalization; IMP:FlyBase.::GO:0051965; P:positive regulation of synapse assembly; IMP:FlyBase.::GO:0031623; P:receptor internalization; IMP:UniProtKB.
17Q62940    887   NEDD4_RAT E3 ubiquitin-protein ligase NEDD4 O...1340.0000003     58.9     28     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0045121; C:membrane raft; IDA:RGD.::GO:0005902; C:microvillus; IDA:RGD.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0008022; F:protein C-terminus binding; IDA:RGD.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
GO:0006955; P:immune response; IEP:RGD.::GO:0030948; P:negative regulation of vascular endothelial growth factor receptor signaling pathway; ISS:UniProtKB.::GO:0070534; P:protein K63-linked ubiquitination; IDA:UniProtKB.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.::GO:0048814; P:regulation of dendrite morphogenesis; IDA:UniProtKB.
18P46935    887   NEDD4_MOUSE E3 ubiquitin-protein ligase NEDD4...1330.0000001     60.5     29     53GO:0005829; C:cytosol; IDA:MGI.::GO:0005624; C:membrane fraction; IDA:MGI.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0000151; C:ubiquitin ligase complex; IPI:MGI.
GO:0050815; F:phosphoserine binding; IDA:BHF-UCL.::GO:0050816; F:phosphothreonine binding; IDA:BHF-UCL.::GO:0070064; F:proline-rich region binding; IPI:MGI.::GO:0019871; F:sodium channel inhibitor activity; IDA:MGI.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:MGI.
GO:0010766; P:negative regulation of sodium ion transport; IDA:MGI.::GO:0030948; P:negative regulation of vascular endothelial growth factor receptor signaling pathway; IDA:UniProtKB.::GO:0045732; P:positive regulation of protein catabolic process; IDA:MGI.::GO:0070534; P:protein K63-linked ubiquitination; ISS:UniProtKB.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.::GO:0048814; P:regulation of dendrite morphogenesis; IMP:UniProtKB.
19Q5BDP1    821   RSP5_EMENI E3 ubiquitin-protein ligase RSP5 O...1810.0000002     59.7     26     52GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
GO:0043328; P:protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway; IDA:UniProtKB.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ISS:RefGenome.
20Q2UBP1    816   RSP5_ASPOR Probable E3 ubiquitin-protein liga...1890.00000005     61.6     28     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro.
21B8N7E5    812   RSP5_ASPFN Probable E3 ubiquitin-protein liga...1880.000000002     65.9     28     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro.
22Q8IVU3    1022   HERC6_HUMAN Probable E3 ubiquitin-protein lig...1460.00000000001     73.6     35     51GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:HPA.
GO:0004842; F:ubiquitin-protein ligase activity; IBA:RefGenome.
GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.
23P46934    1319   NEDD4_HUMAN E3 ubiquitin-protein ligase NEDD4...1240.000001     57     29     52GO:0016327; C:apicolateral plasma membrane; TAS:BHF-UCL.::GO:0005938; C:cell cortex; IDA:BHF-UCL.::GO:0000785; C:chromatin; IDA:BHF-UCL.::GO:0005829; C:cytosol; ISS:BHF-UCL.::GO:0048471; C:perinuclear region of cytoplasm; IDA:BHF-UCL.::GO:0000151; C:ubiquitin ligase complex; ISS:BHF-UCL.
GO:0031698; F:beta-2 adrenergic receptor binding; IDA:UniProtKB.::GO:0050815; F:phosphoserine binding; ISS:BHF-UCL.::GO:0050816; F:phosphothreonine binding; ISS:BHF-UCL.::GO:0070064; F:proline-rich region binding; IPI:UniProtKB.::GO:0019904; F:protein domain specific binding; IPI:UniProtKB.::GO:0070063; F:RNA polymerase binding; IPI:BHF-UCL.::GO:0019871; F:sodium channel inhibitor activity; IDA:BHF-UCL.::GO:0043130; F:ubiquitin binding; IDA:BHF-UCL.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:BHF-UCL.
GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.::GO:0044111; P:development involved in symbiotic interaction; IMP:UniProtKB.::GO:0042921; P:glucocorticoid receptor signaling pathway; IDA:BHF-UCL.::GO:0010766; P:negative regulation of sodium ion transport; IDA:UniProtKB.::GO:0010768; P:negative regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage; IMP:BHF-UCL.::GO:0030948; P:negative regulation of vascular endothelial growth factor receptor signaling pathway; ISS:UniProtKB.::GO:0031175; P:neuron projection development; IEP:BHF-UCL.::GO:0046824; P:positive regulation of nucleocytoplasmic transport; IDA:BHF-UCL.::GO:0014068; P:positive regulation of phosphatidylinositol 3-kinase cascade; IMP:BHF-UCL.::GO:0045732; P:positive regulation of protein catabolic process; IDA:MGI.::GO:0050847; P:progesterone receptor signaling pathway; IDA:BHF-UCL.::GO:0070534; P:protein K63-linked ubiquitination; ISS:UniProtKB.::GO:0006622; P:protein targeting to lysosome; IDA:UniProtKB.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IDA:BHF-UCL.::GO:0032801; P:receptor catabolic process; IDA:UniProtKB.::GO:0031623; P:receptor internalization; IDA:UniProtKB.::GO:0048814; P:regulation of dendrite morphogenesis; ISS:UniProtKB.::GO:0051592; P:response to calcium ion; TAS:BHF-UCL.::GO:0019089; P:transmission of virus; IMP:BHF-UCL.::GO:0043162; P:ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway; IMP:BHF-UCL.
24Q5RBF2    959   NED4L_PONAB E3 ubiquitin-protein ligase NEDD4...1800.000001     57     26     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro.
25Q8CFI0    1004   NED4L_MOUSE E3 ubiquitin-protein ligase NEDD4...1800.000003     55.8     26     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:MGI.::GO:0019871; F:sodium channel inhibitor activity; IDA:MGI.::GO:0004842; F:ubiquitin-protein ligase activity; IBA:RefGenome.
GO:0010766; P:negative regulation of sodium ion transport; IDA:MGI.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.
26Q96PU5    975   NED4L_HUMAN E3 ubiquitin-protein ligase NEDD4...1800.000003     55.5     26     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; NAS:UniProtKB.
GO:0006883; P:cellular sodium ion homeostasis; NAS:UniProtKB.::GO:0007588; P:excretion; NAS:UniProtKB.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0045807; P:positive regulation of endocytosis; NAS:UniProtKB.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.::GO:0042176; P:regulation of protein catabolic process; NAS:UniProtKB.::GO:0010038; P:response to metal ion; IDA:UniProtKB.::GO:0006814; P:sodium ion transport; NAS:UniProtKB.::GO:0030104; P:water homeostasis; NAS:UniProtKB.
27Q0CCL1    808   RSP5_ASPTN Probable E3 ubiquitin-protein liga...1880.000000002     65.9     28     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.
GO:0043328; P:protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway; ISS:UniProtKB.
28A2QQ28    821   RSP5_ASPNC Probable E3 ubiquitin-protein liga...1880.000000004     65.1     28     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.
GO:0043328; P:protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway; ISS:UniProtKB.
29Q4WTF3    813   RSP5_ASPFU Probable E3 ubiquitin-protein liga...1880.000000002     65.9     28     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.
GO:0043328; P:protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway; ISS:UniProtKB.
30B0XQ72    813   RSP5_ASPFC Probable E3 ubiquitin-protein liga...1880.000000002     65.9     28     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.
GO:0043328; P:protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway; ISS:UniProtKB.
31Q1K9C4    1029   YFK7_SCHPO Probable E3 ubiquitin protein liga...1800.00000002     62.8     27     45GO:0005829; C:cytosol; IDA:PomBase.::GO:0005635; C:nuclear envelope; IDA:PomBase.
GO:0004842; F:ubiquitin-protein ligase activity; ISS:PomBase.
GO:0033554; P:cellular response to stress; IEP:PomBase.::GO:0030433; P:ER-associated protein catabolic process; ISS:PomBase.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ISS:RefGenome.
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